Clinical trials: Muscle Disorders
Sarcopenia
Multidisciplinary Combined Exercise and Nutrition Intervention for Sarcopenia (2)
This is an empirical study, which aims to examine the effect of a 12-week combined exercise-nutrition intervention in older adults with sarcopenia and to provide data for clinical and policy decision-making of sarcopenia.
- Trial name
- MENTORS (NCT07028294)
- Testing
- Combined exercise and nutrition intervention
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Bundang Hospital
Cystic Fibrosis
Whole Body Vibration - a New Therapeutic Approach to Improve Muscle Function in CF
The purpose of this study is to evaluate the effects of whole body vibration (WBV) on muscle function in adult CF-patients.
- Trial name
- NCT00388466
- Testing
- GALILEO
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Cologne
Fibromyalgia, Systemic Lupus Erythematosus
Membrane Polyunsaturated Fatty Acid Content in Fibromyalgia and Systemic Lupus Erythematosus (SLE)
Polyunsaturated omega-3 fatty acids (ω3 PUFAs) are essential nutrients. Studies indicate that the incidence of Major Depression (MD) is inversely related to the consumption of fish (which are rich in ω3-PUFAs) and to the…
- Trial name
- NCT01460680
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Urinary Incontinence (UI)
Posture, Core Stabilization, Respiratory Muscle Strength and Quality of Life in Women With Urinary Incontinence
When the literature was examined, it was observed that there were studies on parameters such as quality of life, pelvic floor muscle strength in women with urinary incontinence, but there were not enough studies on posture…
- Trial name
- NCT06988683
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Sarcopenia, Cancer
Leucine-enriched Formulas in Patients With Tumor-induced Sarcopenia
Currently there is a lack of evidence for recommending specific oral supplements (OS) for nutritional support in patients with cancer, including leucine-enriched supplements.
- Trial name
- NCT05837741
- Testing
- Standard hypercaloric hyperproteic oral nutritional supplement, Leucine-enriched hypercaloric hyperproteic oral nutritional supplement
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Orthopaedic Fractures, Orthopaedic Trauma Fractures and Non-unions
Mindfulness in Fracture Recovery and Reduction of Opioid Reliance: Evaluating the Feasibility of Implementing a Brief, Mindfulness-based Intervention to Manage Pain and Anxiety Before and After Fracture Surgery
Breaking a bone is not only physically painful but also emotionally overwhelming. Patients often experience intense pain, anxiety, and uncertainty as they are rushed to hospital, undergo emergency treatment, and prepare for…
- Conditions
- Orthopaedic Fractures, Orthopaedic Trauma Fractures and Non-unions, Orthopaedic Trauma, Orthopaedic Surgery
- Trial name
- MIRROR (NCT07486505)
- Testing
- Mindfulness Based Intervention, Educational Recording
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McMaster University
Muscle Spasticity, Paralysis; Cerebral
The Decline in Walking Performance in Adults With Cerebral Palsy - Influence of Performance Fatigability
Due to an early brain injury occurring in antenatal or postnatal, cerebral palsy (CP) causes alteration in motor function with posture and gait disorders.
- Trial name
- FAT-GAIT (NCT06163950)
- Testing
- Fatigability assessment
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Knee Replacement Arthroplasty, Fibrosis
Knee Stiffness in Fibrosis Diathesis
At the standard follow-up moment one year after primary TKA for gonarthrosis, all patients will be checked for signs of fibrosis diathesis.
- Conditions
- Knee Replacement Arthroplasty, Fibrosis, Dupuytren's Disease
- Trial name
- NCT02294890
- Testing
- Total knee arthroplasty
- Volunteers
- 60 people
- Sponsor
- University Hospital Pellenberg
Duchenne Muscular Dystrophy (DMD)
A Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping to Evaluate the Safety and Efficacy of ENTR-601-45
This is a study of the investigational medicine ENTR-601-45 in participants who have Duchenne muscular dystrophy (DMD), a rare genetic condition.
- Trial name
- ELEVATE-45 (NCT07038824)
- Testing
- ENTR-601-45
- Where
- 15 sites in Belgium, Italy and 3 more
- Volunteers
- 24 people
- Sponsor
- Entrada Therapeutics, Inc.
Carpal Tunnel Syndrome Treatment
Dorsovolar Kinesiotape in Carpal Tunnel Syndrome
This study aimed to compare the short- and medium-term efficacy of dorso-volar kinesiotape (KT) added to home exercises (HE) with sham-KT and HE alone in the treatment of mild or moderate carpal tunnel syndrome (CTS) in terms of…
- Trial name
- NCT05997823
- Testing
- kinesiotape, home exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Selcuk University
Muscle Damage, Muscle Inflammation
The Effects of High Dose Fish Oil Supplementation on Delayed Onset Muscle Soreness and Inflammatory Markers
The purpose of this study is to determine the effects of fish oil supplementation (Lovaza, GlaxoSmithKline) on muscle strength, muscle soreness and inflammation following exercise.
- Trial name
- NCT00805870
- Testing
- Lovaza (omega-3-acid ethyl esters), Wheat Germ Oil
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western Michigan University
Insomnia, Healthy Adult
The Impact of Acute Pain on Sleep Parameters in the Insomnia Population and Healthy Controls
This study investigates how acute exercise-induced muscular pain affects sleep quality and sleep architecture in people with insomnia compared to healthy sleepers.
- Conditions
- Insomnia, Healthy Adult, Sleep, Musculoskeletal Pain
- Trial name
- NCT07826650
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Neuromuscular Diseases
Muscle Oxygenation in Effort in Neuromuscular Diseases
Previous studies showed modifications of muscle oxygenation parameters in muscular dystrophies du to an impairment or an absence of dystrophin.
- Trial name
- OXYNEMU (NCT02789059)
- Testing
- muscle oxygenation
- Where
- 3 sites in France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Rhabdomyolysis
RhabdomYolyse in Intensive caRe
Analysis of the outcome of patients < 18 years old, treated in an intensive care unit for severe rhabdomyolysis, regardless of etiology (renal failure rate, death rate, organ replacement rate)
- Trial name
- RYR (NCT06101680)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Central Hospital, Nancy, France
Knee Osteoarthritis
Exercise With Dual Task in Knee Osteoarthritis
The purpose of this study is to evaluate the neuromuscular and perceptual responses, pain intensity and performance in patients with severe knee osteoarthritis in a preoperative setting with low-load resistance training with a…
- Trial name
- DTOA (NCT05280080)
- Testing
- Resistance exercise
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- University of Valencia
Critical-Illness, Polyneuropathy
Neurological Outcome in Surgical and Non-surgical Septic Patients
Systemic inflammation and sepsis cause multi organ failure including severe neurologic impairment in the course of disease. Neurologic failure typically presents as critical-illness-polyneuropathy/-myopathy and septic…
- Conditions
- Critical-Illness, Polyneuropathy, Myopathy, Septic Encephalopathy
- Trial name
- NOSEPP (NCT02442986)
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- University of Rostock
Supraspinatus Tear or Rupture, Not Specified as Traumatic
Ultrasound of Supraspinatus Muscle Tears
The supraspinatus is a relatively small muscle of the upper back that runs from the supraspinatus fossa superior portion of the scapula to the greater tubercle of the humerus.
- Trial name
- NCT03171883
- Volunteers
- 30 people
- Sponsor
- Assiut University
Infertility, Female, Fibroid Uterus
Impact of Esmya on Fertility to Infertile Women With Fibroids Managed With Assisted Reproduction Techniques
Fibroid is a frequent pathology of infertile women. Its deleterious effect on the infertility would be due to the mechanical way. The interest of the resection of intramural fibroids is discussed.
- Trial name
- NACRE (NCT03349190)
- Testing
- ULIPRISTAL ACETATE
- Where
- 23 sites in France, New Caledonia
- Volunteers
- 127 people
- Sponsor
- ASSOCIATION POUR LE DEVELOPPEMENT EN FECONDATION IN VITRO
Ptosis, Eyelid
Phenylephrine Versus Eyelid Taping for Muller's Muscle-Conjunctival Resection (MMCR) Evaluation
This research study aims to compare whether Phenylephrine 2.5% ophthalmic eye drop solution can serve as a better indicator of the effect of a drooping upper eyelid (ptosis) by covering part of the upper portion of the field of…
- Trial name
- NCT05890027
- Testing
- Phenylephrine Ophthalmic, Eyelid Tape
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Temporomandibular Dysfunction (TMD)
Cervical Proprioception, Masticatory Pain Threshold and Craniovertebral Angle in TMD
Temporomandibular disorder (TMD) is a group of conditions involving the masticatory muscles, temporomandibular joint (TMJ), and associated structures of the head, neck, and cervical region.
- Trial name
- NCT07681570
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
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