Clinical trials: Muscle Disorders
Nocturia, Sleep Deprivation
Abdominal Muscle Exercises on Nocturia and Sleep Quality in Women With Type 2 Diabetes
Nocturia is the leading cause of sleep disruption with its subsequent negative impact on general health and QoL for a large proportion of the adult population.
- Trial name
- NCT05222477
- Testing
- pelvic floor exercise, Abdominal muscles exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Non Ruptured Tendon Injuries, Tendinopathy
Tissue Repair Device (VergenixTM STR) in Patients With Epicondylitis (Tennis Elbow)
The VergenixTM STR device is intended for the repair of non ruptured tendon injuries (Tendinopathy).
- Trial name
- CP-STR-01 (NCT02309307)
- Testing
- Tissue Repair Device (VergenixTM STR)
- Where
- 3 sites in Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Collplant
Isolated Cervical Dystonia, Complex Dystonia
Functional MRI and DTI in the Preoperative Assessment of Dystonia
The aim of this study is to evaluate the organization of the motor circuit in a group of patients suffering from dystonia compared with a group of healthy controls.
- Conditions
- Isolated Cervical Dystonia, Complex Dystonia, Spasticity
- Trial name
- IRMF-DIFF (NCT02877836)
- Testing
- magnetic resonance imaging (fMRI)
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Temporomandibular Disorder
Botulinumtoxin A as a Treatment for Myalgia and Myofacial Pain in Patient With Temporomandibulardisorders
Both patients and remitters ask for treatment with Botulinumtoxin A (BTX) with the hope that it will be an effective aid for pain, but little is known regarding if the effect is dose dependent.
- Trial name
- NCT06941636
- Testing
- 5U/0,1 ml Botulinum toxin A, 10U/0,1 ml Botulinum toxin A
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Region Stockholm
Malnutrition; Moderate
The Correlation Among Nutrition, Muscle Strength, Masticatory and Swallow Ability of Inpatient Elders
The masticatory performance would affect the nutritional status of elderly people. the prevalence of undernutrition among elderly inpatients is %20-50%.
- Trial name
- NMM (NCT04492644)
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- China Medical University Hospital
Stress Urinary Incontinence
Assessment of Pelvic Floor Muscle Training Using Modern Conservative Methods in the Therapy of Stress Urinary Incontinence
The eim is to evaluate the clinical effectiveness of pelvic floor muscle training (PFMT) in conservative therapy in women with objective, urodynamic stress urinary incontinence using home exercise training with the medical…
- Trial name
- Aniball-inco (NCT06673875)
- Testing
- conservative treatment of stress urinary incontinence - pelvic floor muscle training, vaginal device Aniball INCO
- Where
- Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Brno University Hospital
Chronic Low-back Pain, Muscle Atrophy
Effect of an Aquatic Exercise Program in Patients With Chronic Low Back Pain
The goal of this pilot randomized controlled trial is to compare the effects of aquatic therapy versus standard care on paraspinal and gluteal morphology and function in individuals with chronic low back pain.The main questions…
- Conditions
- Chronic Low-back Pain, Muscle Atrophy, Diagnostic Imaging, Exercise Therapy
- Trial name
- NCT05823857
- Testing
- Aquatic Therapy, Standard Care
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Concordia University, Montreal
Fibromyalgia
Exercise-based Motivational Interviewing for Fibromyalgia
Fibromyalgia (FMS), defined as the presence of both chronic widespread pain and the finding of 11/18 tender points on examination, affects 2% of the general population.
- Trial name
- NCT00573612
- Testing
- Attention Control Counseling, Motivational Interviewing
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Subacute Stroke, Balance Deficits
Effects of Inspiratory Muscle Training and Abdominal Drawing-In Maneuver on Balance, Gait and Pulmonary Function in Stroke Patients
This study examines how Inspiratory Muscle Training (IMT) combined with the Abdominal Drawing-In Maneuver (ADIM) affects balance, gait, and breathing in stroke patients.
- Trial name
- NCT06838871
- Testing
- Inspiratory Muscle Training (IMT) with Abdominal Drawing-In Maneuver (ADIM) training
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Sahmyook University
COPD
Impact of COPD on Muscle Regeneration
Muscle weakness and atrophy are important consequences of chronic obstructive pulmonary disease (COPD) and can affect both respiratory and peripheral muscles.
- Trial name
- NCT02557165
- Testing
- Muscle biopsies
- Volunteers
- 27 people
- Sponsor
- Laval University
Duchenne Muscular Dystrophy
A Pharmacokinetic Study of Oral Deflazacort in Children and Adolescent Subjects With Duchenne Muscular Dystrophy
Study to characterize the single-state and steady-state dosing of oral deflazacort in pediatric and adolescents subjects.
- Trial name
- NCT02251600
- Testing
- Deflazacort
- Where
- 4 sites in United States
- Volunteers
- 24 people
- Sponsor
- PTC Therapeutics
Spasticity, Muscle
Dry Needling and Botulinum Toxin in the Management of Poststroke Spasticity
Stroke is a clinical picture that can result in loss of motor, sensory and cognitive functions or coma. Approximately 75% of stroke survivors develop disability and one of the causes of disability is the presence of spasticity.
- Trial name
- NCT03747900
- Testing
- Botulinum Toxin Type A, Botulinum Toxin Type A and dry needling.
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Tennis Elbow, Lateral Epicondylitis
The Effect of Blood Flow Restriction Training on Tennis Elbow
The goal of this randomized controlled clinical trial is to investigate the effects of blood flow restriction training on the parameters surrounding tennis elbow afflicted patients including pain, disability, and grip strength.
- Conditions
- Tennis Elbow, Lateral Epicondylitis, Lateral Epicondylitis, Unspecified Elbow
- Trial name
- NCT06490692
- Testing
- Blood Flow Restriction Training, Conventional Strength Training
- Where
- Lebanon
- Volunteers
- 25 people
- Sponsor
- Cairo University
Traumatic Brain Injury
Functional and MRI Evaluation of the Robot-assisted and Traditional Rehabilitation Programs on the Muscle
Walk recovery is one of the goals of rehabilitation programs in patients with acquired brain injury. Recent experiences have shown the effectiveness of rehabilitation programs including traditional physiotherapy in combination…
- Trial name
- NCT04768192
- Testing
- Physical Rehabilitation without lokomat, Physical Rehabilitation with Lokomat
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Eugenio Medea
Multiple Sclerosis, Spasticity, Muscle
Performance and Long-term Safety of FlowOx2.0™, Multiple Sclerosis, Spasticity and Pain
This study is based on a 4-week double-blind, randomized, controlled, parallel design investigation to investigate the impact of intermittent negative pressure on spasticity and pain in people with multiple sclerosis (pwMS)…
- Conditions
- Multiple Sclerosis, Spasticity, Muscle, Pain
- Trial name
- NCT05598736
- Testing
- FlowOx 2.0
- Where
- Norway
- Volunteers
- 58 people
- Sponsor
- Otivio AS
Bruxism
Neuromuscular Function and Performance in Athletes With or Without Bruxism
The aim of this study is to evaluate the associations between bruxism and neuromuscular function, as well as athletic performance, in a population of amateur athletes.
- Trial name
- CHAINSPORT (NCT07556211)
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mainjot Amélie
Marfan Syndrome
Cardiorespiratory and Muscular Rehabilitation of Children and Young Adults With Marfan Syndrome.
Marfan syndrome (MFS) is a rare genetic disease (1/5000) characterized by the association of ocular impairment, cardiovascular disease and musculoskeletal disease.
- Trial name
- Marfanpower (NCT03236571)
- Testing
- Rehabilitation program
- Where
- France
- Volunteers
- 28 people
- Sponsor
- University Hospital, Toulouse
Obesity, Overweight
A Study to Investigate Weight Management With Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Adults With Obesity or Overweight
The main purpose of this study is to evaluate the efficacy and safety of Bimagrumab and Tirzepatide, alone or in combination, in adults with obesity or overweight, with at least one obesity related comorbidity, without Type 2…
- Trial name
- NCT06643728
- Testing
- Bimagrumab, Tirzepatide
- Where
- 12 sites in United States
- Volunteers
- 252 people
- Sponsor
- Eli Lilly and Company
Sarcopenia, Critical Illness
ICU Sarcopenia Rates by Abdominal CT: Sepsis vs. Trauma
Using abdominal computed tomography (CT) imaging, the investigators will estimate total body muscle mass at two time points in Intensive Care Unit (ICU) by assessing cross-sectional muscle areas at the L3 vertebral body level.
- Conditions
- Sarcopenia, Critical Illness, Sepsis, Trauma
- Trial name
- NCT03982628
- Testing
- Abdominal CT imaging
- Where
- Canada
- Volunteers
- 146 people
- Sponsor
- University of Calgary
Acute Heart Failure, Congestive Heart Failure
The Role of intraABDOminal Pressure and Point Of Care UltraSound to Guide Decongestive Therapy in Heart Failure
Systemic venous congestion is the primary therapeutic target of intravenous loop diuretics in patients admitted for acute heart failure (AHF).
- Conditions
- Acute Heart Failure, Congestive Heart Failure, Intraabdominal Hypertension, Cardio-Renal Syndrome
- Trial name
- ABDOPOCUS-HF (NCT07008365)
- Testing
- Furosemide 20 Milligrams
- Where
- 2 sites in Spain
- Volunteers
- 168 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
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