Clinical trials: Muscle Disorders
MSDs, Muscle Pain
Team-based Ergonomics Educational Model for Workplace WELLNESS Improvement: A Pilot Study
This research is being done to explore the potential benefit of a physical therapist-guided stretching program on musculoskeletal pain and well-being.
- Trial name
- TEEM WELLNESS (NCT03831737)
- Testing
- stretching exercises
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Adhesive Capsulitis
Comparative Effect of ART and MET on Pain, ROM and Functional Disability in AC Patients With Trigger Points
The aim of this study to determine the Comparative effect of active release technique and muscle energy technique on pain, ROM and functional disability in adhesive capsulitis patients with trigger points.
- Trial name
- NCT05448612
- Testing
- Active Release Technique and muscle energy technique
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- University of Lahore
Muscle Atrophy
Protein Ingestion and Skeletal Muscle Atrophy
The effect of different protein intakes on skeletal muscle atrophy during short term unilateral leg immobilisation.
- Trial name
- NCT03797781
- Testing
- Lower limb immobilisation (leg brace) with varying levels of protein intake
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Childhood Soft Tissue Sarcoma, Childhood Liver Cancer
Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of liposomal doxorubicin in treating children who have…
- Conditions
- Childhood Soft Tissue Sarcoma, Childhood Liver Cancer, Bone Cancer, Brain Tumor
- Trial name
- NCT00019630
- Testing
- doxorubicin HCl liposome
- Where
- 2 sites in United States
- Sponsor
- National Cancer Institute (NCI)
Tendinopathy
Eccentric Exercise in Epicondylitis
There is more and more evidence of the importance of the role of kinesitherapy in the management of epicondylitis, specifically (but not exclusively) of eccentric exercise.
- Trial name
- NCT03996928
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Andaluz Health Service
Spinal Muscular Atrophy Type II, Spinal Muscular Atrophy Type III Non Ambulant
Safety and Efficacy of Olesoxime (TRO19622) in 3-25 Years SMA Patients.
Assess the efficacy and the safety of olesoxime in SMA type 2 or type 3 non ambulant patients aged 3-25 years
- Trial name
- NCT01302600
- Testing
- Olesoxime
- Where
- 22 sites in Belgium, France and 5 more
- Volunteers
- 165 people
- Sponsor
- Hoffmann-La Roche
Pain, Postoperative, Coronary Artery Disease
Pecto-Intercostal Fascial Block vs. Transversus Thoracic Muscle Plane Block in Cardiac Surgery
In patients undergoing open cardiac surgery, pain control is an essential part of the enhanced recovery process. The current study aimed to evaluate the analgesic efficacies of ultrasound-guided pecto-intercostal fascial block…
- Trial name
- NCT04791592
- Testing
- Single-injection, ultrasound-guided bilateral PIF block., Single-injection, ultrasound-guided bilateral TTMP block.
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ondokuz Mayıs University
Recurrent or Refractory Solid Tumors, Ewing Sarcoma
Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors
This is a Phase 1 study of the combination of two drugs: MM-398 and Cyclophosphamide. The goal is to find the highest dose of MM-398 that can be given safely when it is used together with the chemotherapy drug Cyclophosphamide.
- Conditions
- Recurrent or Refractory Solid Tumors, Ewing Sarcoma, Rhabdomyosarcoma, Neuroblastoma
- Trial name
- NCT02013336
- Testing
- MM-398 (Irinotecan Sucrosofate Liposome Injection) plus cyclophosphamide
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- South Plains Oncology Consortium
Obesity, Type 2 Diabetes Mellitus
Molecular Regulation of Muscle Glucose Metabolism
This protocol is being conducted to determine the mechanisms responsible for insulin resistance, obesity and type 2 diabetes.
- Trial name
- NCT01581736
- Testing
- U100 Humulin, Exercise
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Fibromyalgia
The Effect of Tai Chi in Treating Fibromyalgia
To evaluate the effect of Tai chi on Fibromyalgia
- Trial name
- NCT02257034
- Testing
- Taichi, Dance
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Chengdu PLA General Hospital
Sarcopenia, Arteriosclerosis
Effects of Lower Body EMS Training in Postmenopausal Women
This study evaluates the effects of a 8-week lower body Electrical Muscle Stimulation (EMS) training program on body composition, muscle function, and arteriosclerosis markers in postmenopausal women.
- Conditions
- Sarcopenia, Arteriosclerosis, Arterial Stiffness, Blood Pressure, Postmenopausal Women
- Trial name
- LB-EMS-PMW (NCT07385534)
- Testing
- Lower-body Electromyostimulation (LB-EMS) device, Lower Body Resistance Training
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Seoul National University
Fibromyalgia, Chronic Low-back Pain
Effects of the COVID-19 Pandemic on Fibromyalgia Patients
In this study, the effects of the symptoms related to the diseases of patients with fibromyalgia during the COVID-19 pandemic, their limitations in their social and business life, the need for different drugs, stress levels and…
- Trial name
- NCT04730934
- Testing
- Perceived stress scale, Fibromyalgia impact questionnaire, The drugs used before and during the pandemic, the patient's job status, physical activity conditions, pain status
- Where
- Turkey (Türkiye)
- Volunteers
- 1,360 people, healthy volunteers welcome
- Sponsor
- Kars State Hospital
Tendinopathy, Rotator Cuff
Real Dry Needling and Placebo Dry Needling Applied With and Without Ultrasound Guidance on the Infraspinatus Muscle
The infraspinatus muscle is one of the four muscles that form the rotator cuff. The dry needling technique involves inserting a sterile needle to stimulate a myofascial trigger point with the aim of reducing pain and increasing…
- Trial name
- DN-INFR-RCT (NCT06583707)
- Testing
- Dry needling with and without ultrasound guidance
- Where
- Spain
- Volunteers
- 76 people
- Sponsor
- University of Alcala
Lateral Epicondylitis, Tennis Elbow
Effectiveness of the Astym Technique, the Graston Technique, and Therapeutic Ultrasound in the Treatment of Lateral Epicondylosis.
The purpose of this study is to examine the effectiveness of three common techniques for the treatment of lateral epicondylosis.
- Conditions
- Lateral Epicondylitis, Tennis Elbow, Posterolateral Rotator Instability
- Trial name
- NCT03234192
- Testing
- Therapeutic ultra sound, Astym Treatment Technique, Graston Treatment Technique
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- NYU Langone Health
Temporomandibular Disorders (TMD)
Effects of a Biopsychosocial Approach Added to Physiotherapy in Temporomandibular Disorders
Temporomandibular disorders are conditions that affect the jaw joint and surrounding muscles and may cause pain, limited jaw movement, stress, sleep problems, and teeth grinding.
- Trial name
- TMD-BPS (NCT07320144)
- Testing
- Physiotherapy Program, Biopsychosocial Intervention
- Volunteers
- 40 people
- Sponsor
- Betül Özata
Diabetic Neuropathy, Sarcopenia
The Relation Between Diabetic Neuropathy and Muscle Mass in Type 2 Diabetes Mellitus Patients
The goal of this observational study is to evaluate the relation between diabetic neuropathy in type 2 diabetes mellitus patients and muscle mass
- Trial name
- NCT06958302
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Critical Illness
Quadriceps Muscle Activation and Oxygenation Responses During Usual Care Compared to Individualized Interval and Constant Work Rate Bed-cycling. An Experimental Study.
### Study Summary - AcuteBike-ICU Bed-cycling is commonly used as part of early rehabilitation in critically ill patients in the intensive care unit (ICU).
- Trial name
- AcuteBike-ICU (NCT07882719)
- Testing
- usual care constant work rate bedcycling, Individualized constant work rate bedcycling, Individualized interval bedcycling
- Volunteers
- 29 people
- Sponsor
- KU Leuven
Sarcopenia, Anabolic Resistance
Strength Training and Resveratrol
The main goal of this study is to find out if supplementing with resveratrol improves skeletal muscle adaptations to strengthening exercise (resistance training or strength training) in adults age 60+, and to determine whether…
- Trial name
- STaR (NCT06585865)
- Testing
- Resistance training, Resveratrol 500 mg oral once daily.
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Musculoskeletal Pain, Acute Pain
A Randomized Trial of NSAID Dosing Strategies
This study will compare the efficacy of two different non-steroidal anti-inflammatory drugs (NSAIDs) ketorolac and ibuprofen for people with acute moderate or severe musculoskeletal pain.
- Trial name
- NCT05239767
- Testing
- NSAID
- Where
- United States
- Volunteers
- 407 people
- Sponsor
- Montefiore Medical Center
Sports Physical Therapy
Comparative Effects of High and Moderate Intensity Resistance Training in Young Football Players
Football playing is an intermittent sport requiring high intensity dynamic movements, such as acceleration, sprinting and jumping. Higher levels of strength and power are crucial for young football players.
- Trial name
- NCT06479551
- Testing
- high intensity-low volume resistance training, Moderate intensity-high volume resistance training
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Riphah International University
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