Clinical trials: Muscle Disuse Atrophy, active
Muscle Atrophy, Disuse Atrophy
Effect of Knee Position on Muscle Loss During Leg Immobilization
This study looks at what happens to leg muscles when the knee is kept straight or bent during five days of wearing a brace. We want to find out if keeping the knee bent (so the thigh muscle is stretched) helps prevent muscle loss…
- Conditions
- Muscle Atrophy, Disuse Atrophy, Immobilization
- Trial name
- NCT07690150
- Testing
- Knee immobilization brace (0°) for 5 days, Knee immobilization brace (60°) for 5 days
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Atrophy of Muscle Due to Disuse, Rehabilitation
Sex-specific Determinants of Early-phase Recovery From Skeletal Muscle Disuse
This project is a 2-phase, randomized clinical trial that includes 7 days of unilateral leg disuse (Phase 1), immediately followed by 1 week of bilateral leg rehabilitation (Phase 2).
- Trial name
- MAC (NCT04151901)
- Testing
- Resistance Exercise Rehabilitation, Walking-based rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Mitochondrial Energetics, Dietary Nitrate
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men
Diminished use of skeletal muscle, such as occurs with many chronic diseases (e.g., heart failure or cancer cachexia), denervation, bedrest, immobilization (e.g., limb casting or bracing), etc., is a common clinical condition…
- Conditions
- Mitochondrial Energetics, Dietary Nitrate, Disuse Atrophy (Muscle) of Lower Leg
- Trial name
- NCT07161973
- Testing
- Beetroot Juice - Active
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Indiana University
Muscle Disuse, Muscle Disuse Atrophy
Muscle Response to Different Amounts of Dietary Protein During Leg Immobilization
Individuals who sustain musculoskeletal injuries (MSKI) can experience a rapid loss of muscle mass due to declines in muscle loading and activation that occur post-injury (i.e., disuse atrophy).
- Trial name
- NCT07069426
- Testing
- 20 grams protein, 40 grams protein
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Healthy, Muscle Disuse Atrophy
The Effects of Protein Supplementation With or Without Urolithin A During Single-leg Immobilization
There are times in life when people cannot use their muscles, such as during illness or injury. Muscle and mitochondria (the 'energy factory' in cells) health decline very quickly when people cannot use their muscles, but certain…
- Trial name
- NCT05814705
- Testing
- Protein supplement, Protein supplement with Urolithin A
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- McMaster University