Clinical trials: Muscle Dysfunction
Temporomandibular Disorder, Neck Pain
Effect of Manual Therapy on Temporomandibular Joint Dysfunction
Temporomandibular disorders (TMD) are multifactorial conditions involving the temporomandibular joint and masticatory muscles, often presenting with pain and functional limitations.
- Trial name
- NCT07210957
- Testing
- Manual Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Abant Izzet Baysal University
Diastasis of m. Rectus Abdominis
Prevalence of Diastasis m. Rectus Abdominis in Postpartum Women
This study will evaluate the prevalence of diastasis m. rectus abdominis after delivery. Relationship of Diastasis Recti Abdominis with urine leakage, pelvic floor muscle function and morphometry in postpartum women.
- Trial name
- NCT05051176
- Testing
- 2D usg and 3D/4D usg
- Where
- Slovakia
- Volunteers
- 150 people
- Sponsor
- Pavol Jozef Safarik University
Ankylosing Spondylitis
Prevalence of Temporomandibular Joint Dysfunction in Patients With Ankylosing Spondylitis
This study included 113 patients diagnosed with ankylosing spondylitis and 110 healthy volunteers. Participants in both groups were evaluated using the 'Diagnostic Criteria for Temporomandibular Disorders (DC/TMD)' diagnostic…
- Trial name
- NCT05839925
- Testing
- Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) Axis I and II
- Where
- Turkey (Türkiye)
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Fibromyalgia
The Effect of Core Exercises on Pelvic Dysfunction, Sexual Dysfunction, Pain, Sleep Quality and Quality of Life in Women With Fibromyalgia
In fibromyalgia patients, exercise is needed to reduce symptoms and to prevent muscle weakness with fatigue and pain. Core exercise retrains and strengthens deep postural spinal muscles such as the multifidus and transverse…
- Trial name
- NCT06038214
- Testing
- core exercises, home exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Inonu University
Sacroiliac Joint Dysfunction
Effects of Stecco Fascial Manipulation Versus Muscle Energy Technique on Pain Pressure Threshold, Range of Motion and Disability Among Patients With Sacroiliac Joint Dysfunction
This study holds significant importance as it directly addresses the need for effective physiotherapy interventions in patients with sacroiliac joint dysfunction, a condition that contributes substantially to lower back pain and…
- Trial name
- NCT07723014
- Testing
- Stecco fascial manipulation, Muscle energy technique
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Temporomandibular Disorder, Temporomandibular Joint Disorders
Effect of Exercises on Convergence Insufficiency in Individuals With Temporomandibular Disorders
Temporomandibular Disorder is a disorder that involves the muscles of mastication, the temporomandibular joint (TMJ), and associated structures.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome, Convergence Insufficiency
- Trial name
- NCT05761106
- Testing
- Oculomotor Therapy, Therapy for Temporomandibular Disorder
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Nove de Julho
Temporal Mandibular Joint Dysfunction
Effect of Rocabado Exercises With Strain Counter-Strain Technique on Muscles of Mastication for Pain, Jaw Function, and Quality of Life in Patients With Temporomandibular Joint Dysfunction
Temporomandibular joint dysfunction (TMD) is a common musculoskeletal disorder affecting the jaw joint and masticatory muscles, leading to pain, limited jaw function, and reduced quality of life.
- Trial name
- NCT07703059
- Testing
- Rocabado Exercise, Strain Counterstrain Technique
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Chronic Kidney Disease(CKD), Myosteatosis
The Effect of the Nutraceutical (-)- Epicatechin on Myosteatosis in Patients With Advanced CKD
Some foods have components that can prevent and treat some diseases and provide beneficial effects for health. These components naturally occurring in foods are called nutraceuticals.
- Conditions
- Chronic Kidney Disease(CKD), Myosteatosis, Mitochondrial Dysfunction, Muscle Function
- Trial name
- EPIC-CKD (NCT06631820)
- Testing
- Epicatechin extract
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Karolinska Institutet
Erectile Dysfunction
A Bioavailability Study of LY2452473 and Tadalafil
This study compares LY2452473 taken orally as a 5 milligram (mg) capsule at the same time as a 5 mg tadalafil tablet with three different combination tablets (LY900010) of 5 mg LY2452473 and 5 mg tadalafil taken orally.
- Trial name
- NCT01401543
- Testing
- LY2452473, Tadalafil, LY900010
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Muscle Weakness, Bone Health
Healthy Older People Everyday (HOPE) - Role of Healthy Diet on Muscle and Bone Health
Certain clinical syndromes eg frailty, sarcopenia, dementia, depression, cognitive impairment, vision impairment and falls in older adults carry an increased risk for poor health outcomes and if identified early, can be…
- Conditions
- Muscle Weakness, Bone Health, Cognitive Decline
- Trial name
- HOPE-DIET (NCT03786835)
- Testing
- Protein supplementation and regular physical activity
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Chronic Temporomandibular Disorders (TMD)
Endogenous Pain Inhibition Deficiency in Chronic TMD Pain
Temporomandibular disorders (TMDs) involve a range of conditions with varied causes, affecting a large portion of the U.S. population and posing challenges for diagnosis and management, especially in chronic cases.
- Trial name
- TMD-CPM (NCT06617494)
- Testing
- Pain modulation testing
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Temporomandibular Joint Dysfunction
Telerehabilitation Dual-Task Training in Temporomandibular Joint Dysfunction
This randomized controlled trial will be conducted among 18-25-year-old participants who present with temporomandibular joint dysfunction symptoms, including pain, limited range of motion, and joint crepitation.
- Trial name
- NCT07556510
- Testing
- Standard Physiotherapy Program, Dual-Task Training
- Volunteers
- 30 people
- Sponsor
- Ege University
Duchenne Muscular Distrophy (DMD)
Endomysial Fibrosis, Muscular Inflammatory Response and Calcium Homeostasis Dysfunction in Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is the most common and devastating form of muscular dystrophy, caused by an X-chromosome gene mutation resulting in the absence of the protein dystrophin.
- Trial name
- NCT01823783
- Testing
- Muscle biopsy
- Where
- 7 sites in France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Temporomandibular Joint Disorders, Pain
Pain, Central Sensitization, Kinesiophobia and Stress Level in Individuals With Temporomandibular Dysfunction
Temporomandibular dysfunction (TMD) is a musculoskeletal and neuromuscular system-related condition that affects the masticatory muscles, temporomandibular joint, and other related structures.
- Trial name
- NCT05993494
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Karadeniz Technical University
Musculoskeletal Pain, TMJ Pain
Association of Jaw Dysfunction With Neck Disability in Subjects With Chronic Cervical Spine Disorders
Since TMJ and cervical pain incidence are rising and both structures are highly interrelated anatomically and functionally. And yet no standard protocol for TMD therapy The objective of this study is to state if there is a…
- Conditions
- Musculoskeletal Pain, TMJ Pain, Cervical Pain
- Trial name
- NCT04849442
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Horus University
Chronic Fatigue Syndrome
Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder
The pathogenesis of chronic fatigue syndrome (CFS) is poorly understood and no effective therapy has been developed. Recent studies suggest that a preceding viral infection causes mitochondrial dysfunction of the brain and…
- Trial name
- CFS:M (NCT01471652)
- Testing
- Nutraceutical supplements
- Where
- United States
- Sponsor
- Columbia University
Facial Pain, Temporomandibular Disorder
Physical Exercises for Temporomandibular Disorders
Temporomandibular Disorders are a common clinical picture that appear in particular in people between the age of 20 and 40 years. About 33% of the total population shows symptoms and signs of TMD.
- Conditions
- Facial Pain, Temporomandibular Disorder, Temporomandibular Joint Disorders, Temporomandibular; Functional Disturbance
- Trial name
- NCT04819763
- Testing
- Physical therapy, Appliance therapy
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Medicine Greifswald
Rheumatic Diseases, Temporomandibular Joint Dysfunction
Treatment in Individuals With Rheumatoid Arthritis Who Have Temporomandibular Joint Dysfunction
This study was conducted to investigate the effect of manual therapy applications on pain, range of motion and joint position sense in individuals with rheumatoid arthritis who have temporomandibular joint dysfunction.
- Conditions
- Rheumatic Diseases, Temporomandibular Joint Dysfunction, Manuel Therapy
- Trial name
- NCT07171671
- Testing
- exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Sanko University
Liver Diseases, Intra-Abdominal Hypertension
Organ Dysfunction Associated With Intra Abdominal Pressures in Liver Transplantation
Patients with end stage liver disease have varying degrees of intra-abdominal hypertension (IAH) due to the presence of ascites. The perioperative events may either relieve or aggravate the intra-abdominal pressures.
- Conditions
- Liver Diseases, Intra-Abdominal Hypertension, Cirrhosis, Liver, Organ Dysfunction Syndrome
- Trial name
- OIL (NCT04463745)
- Where
- India
- Volunteers
- 25 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Epilepsy, Cognitive Dysfunction
Cognitive Function and Glymphatic System in Children with Epilepsy
Epilepsy, one of the most common neurological disorders in childhood, is a chronic brain disease characterized by neurobiological, psychological and cognitive effects.
- Conditions
- Epilepsy, Cognitive Dysfunction, Seizure, Epileptic
- Trial name
- NCT06143241
- Testing
- Threshold IMT, Antiepileptic medication
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ege University