Clinical trials: Muscle Dysfunction
Urology, Pediatric Disorder
Pelvic Floor Muscle Training and Dynamic Neuromuscular Stabilization Exercises in Pediatric Patients
Dysfunctional voiding (DY) is one of the most common conditions in children. Various treatments are available. Participants will be randomly assigned to either PFMT (Group I) or PFMT+DNS (Group II).
- Trial name
- NCT07267364
- Testing
- PFMT
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Sarcopenia, Frailty at Older Adults
Targeting Sarcopenia and Frailty: Multicomponent Exercise With Focal Muscle Vibration
This study aimed to evaluate the efficacy of multicomponent exercises (aerobic exercises, strength exercises, and balance exercises), individualized with the application of a focal muscle vibration machine at the lower…
- Conditions
- Sarcopenia, Frailty at Older Adults, Cognitive Impairment, Adherence
- Trial name
- NCT07049809
- Testing
- Focal Muscle Vibration, Multicomponent Exercise
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Chronic Fatigue Syndrome., Muscular Diseases.
Clinical Trial to Evaluate the Effectiveness of Acupuncture as a Treatment in Patients Diagnosed With CFS.
background: The Chronic Fatigue Syndrome (CFS) presents many disturbances multidimensional affect holistically to people who have the disease and current management of fatigue, pain, anxiety, depression and sleep disturbances…
- Conditions
- Chronic Fatigue Syndrome., Muscular Diseases., Cognitive Impairment, Sleep Disturbances
- Trial name
- AV/AS (NCT01907711)
- Testing
- Acupuncture.
- Where
- 2 sites in Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Vall d'Hebron
Pneumatic Tourniquet, Muscle Weakness
Effect of Tourniquet Use on Muscle Thigh Function.
The use of a pneumatic tourniquet with the purpose of maintaining an operative field free of blood is a common practice in orthopedic surgery.
- Trial name
- NCT03473106
- Testing
- Pneumatic tourniquet use
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- University of Chile
Female Sexual Dysfunction
Predicting Changes in Core Muscles During Female Sexual Dysfunction: A Comprehensive Analysis Using Machine and Deep Learning
The purpose of this study is to Predicting changes in core muscles during female sexual dysfunction by A Comprehensive Analysis Using Machine and Deep Learning Female sexual dysfunction (FSD) is a common condition that affects…
- Trial name
- NCT05833685
- Testing
- no intervention
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Deraya University
Temporomandibular Dysfunction
Effects of Rocabado's Approach Versus Kraus Exercise Therapy
TMJ dysfunction is linked to trauma, joint overloading owing to para-functional behaviors, mechanical stress, and metabolic issues.
- Trial name
- NCT05618938
- Testing
- Rocabado's approach, Kraus exercises
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Myofascial Pain - Dysfunction Syndrome of TMJ
Evaluation of the Effect of Occlusal Splint Use on Masticatory Muscles
"Female patients who applied to the 'Temporomandibular Disorders (TMD) Clinic' at the Department of Prosthodontics, Istanbul University Faculty of Dentistry, with complaints of muscle pain in the maxillofacial region and who are…
- Trial name
- NCT06675747
- Testing
- Ultrasound imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul University
Temporomandibular Joint Dysfunction
Magnetic Ressonance Imaging of Temporomandibular Joint
Background: Among the instrumental devices that have been proposed over the years to integrate the clinical evaluation of temporomandibular joint disorders (TMD), imaging techniques are the most studied, showing that magnetic…
- Trial name
- MRITMJ (NCT02294799)
- Testing
- Intervention Group
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Daniela Ap. Biasotto-Gonzalez
Aortic Regurgitation
Diastolic Dysfunction in Aortic Regurgitation
Follow-up study in patients with severe aortic regurgitation after successful valve replacement. Systolic and diastolic function were assessed and persistent diastolic dysfunction was observed late (7-10 years) after operation.
- Trial name
- NCT00976625
- Testing
- Aortic Valve Replacement
- Where
- Switzerland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Bern
Pelvic-floor Disorders
Patient Evaluation of Treatment of Pelvic-floor Muscle Dysfunction.
Pelvic-floor muscle dysfunction (PFMD) affects 25% of women. It involves urinary and faecal incontinence, prolapse, sexual dysfunction, pelvic pain, and is associated with psycho-social issues (depression, anxiety), impacting…
- Trial name
- NCT06961513
- Testing
- Women's health physiotherapy
- Where
- United Kingdom
- Volunteers
- 700 people
- Sponsor
- Swansea University
Female Sexual Dysfunction
Investigation of Awareness Levels of Women Living in Turkey About Kegel Exercises and Pelvic Floor Muscles
Pelvic floor disorders affect millions of women and their lives in our country and around the world. Along with many factors such as age, obesity, menopause, smoking, number of births and mode of delivery, there is an increase in…
- Trial name
- NCT05806424
- Where
- Turkey (Türkiye)
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Cancer, Sarcopenia
JUMP Prevalence of Sarcopenia and Chemobrain in Post-cancer Patients
Therapeutic advances in oncology have transformed the prognosis of cancer patients, placing a significant number of them either in a context of recovery or in prolonged remission close to a chronic disease.
- Trial name
- JUMP (NCT05800535)
- Testing
- Study of the adverse effects of long-term oncological treatments, Study of the long-term side effects of oncological treatments on the anxiety-depressive and cognitive state of patients
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Fibromyalgia Syndrome, Fibromyalgia Impact Questionnaire
Effects of Conscious Connected Breathing Exercises on Fibromyalgia
Our aim in this study is to investigate the effects of conscious connected breathing exercises on sexual function, sleep, and mood in fibromyalgia patients.
- Conditions
- Fibromyalgia Syndrome, Fibromyalgia Impact Questionnaire, Breathing Pattern Disorder, Female Sexual Dysfunction (FSD)
- Trial name
- NCT07030374
- Testing
- conscious connected breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Adana City Training and Research Hospital
Community-Dwelling Older Adults, Aging
The Efficacy of a Technology-Assisted Block Training Program on Cognitive Function, Hand Dexterity, and Grip Strength in Community-Dwelling Older Adults: A Mixed-Methods Research
Block-building activities represent a promising tool for enhancing cognitive and hand function in older adults. When integrated with technological support, they offer personalized training advantages; however, their comprehensive…
- Conditions
- Community-Dwelling Older Adults, Aging, Cognitive Decline, Hand Dexterity
- Trial name
- NCT07315724
- Testing
- Technology-Assisted Block Training Program
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Respiratory Insufficiency, Weaning, Ventilator
Parasternal Intercostal Ultrasound vs RSBI for Weaning Prediction
Mechanical ventilation is essential in the management of critically ill patients, but deciding the proper time to wean and extubate remains a significant challenge.
- Conditions
- Respiratory Insufficiency, Weaning, Ventilator, Respiration, Artificial, Intensive Care Units
- Trial name
- NCT07144878
- Testing
- Parasternal Intercostal Ultrasound and RSBI Assessment
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Benha University
Cardiac Surgery
Cardiac Surgery and Diaphragm Function
Diaphragm dysfunction is common after cardiac surgery and may delay weaning from mechanical ventilation and cause respiratory distress.
- Trial name
- NCT02208479
- Testing
- Non invasive ultrasound measurement of the diaphragm thickness during breathing
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Grenoble
Spinal and Bulbar Muscular Atrophy
Clinical Trial of Mexiletine Hydrochloride for Spinal and Bulbar Muscular Atrophy
The purpose of this clinical trial is to evaluate the efficacy and safety of mexiletine hydrochloride in patients with spinal and bulbar muscular atrophy.
- Trial name
- Med-SBMA (NCT06862596)
- Testing
- Mexiletine hydrochloride
- Where
- 5 sites in Japan
- Volunteers
- 68 people
- Sponsor
- Masahisa Katsuno
Deglutition Disorders
Study of a Series of Patients Treated for Retrograde Cricopharyngeal Muscle Dysfunction Syndrome
R-CPD syndrome (Retrograde Cricopharyngeal Dysfunction syndrome) is an inability to burp. It is a syndrome whose diagnosis is clinical, and for which there is effective treatment.
- Trial name
- R-CPD-Syndrome (NCT06174831)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Down Syndrome, Autonomic Dysfunction
Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome
Down syndrome (DS), the most common genetic cause of intellectual disability, is associated with widespread organ dysfunction, including abnormalities in the autonomic nervous system (ANS).
- Trial name
- DIVE (NCT07238465)
- Testing
- Cold Stress, Maximal Dynamic Exercise, Isometric Handgrip Exercise with Post-Exercise Muscle Ischemia
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Chronic Low Back Pain, Urinary Incontinence
Radiofrequency and Pelvic Floor-Core Exercise for Chronic Low Back Pain in Women With Pelvic Floor Dysfunction
The goal of this clinical trial is to learn whether capacitive-resistive radiofrequency, a supervised core and pelvic floor exercise programme, or both together reduce low back pain in premenopausal women with chronic…
- Conditions
- Chronic Low Back Pain, Urinary Incontinence, Pelvic Floor Disorders
- Trial name
- NCT07906431
- Testing
- Capacitive-resistive radiofrequency, Lumbopelvic-pelvic floor therapeutic exercise
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- SERGIO MONTERO NAVARRO