Clinical trials: Muscle Dysfunction
Temporomandibular Disorders (TMDs)
Investigation of the Effects of Different Treatment Approaches in Jaw (Temporomandibular) Joint Disorders
Temporomandibular joint disorders (TMD) are common conditions that may cause jaw pain, limited jaw movement, and reduced quality of life.
- Trial name
- NCT07392671
- Testing
- Conventional Physiotherapy and Rehabilitation Program, Limbic-Oriented Manual Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Pelvic Floor Abnormalities
Pelvic Floor Exercises During Gestation in the Prevention of Urinary Incontinence and Pelvic Floor Muscle Dysfunction
Urinary incontinence is any involuntary loss of urine. During gestation, hormonal and mechanical factors favor the incidence of urinary loss that may persist after delivery in up to 50% of women.
- Trial name
- NCT00740428
- Testing
- Pregnants for receive the physical therapy guide
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Neuromuscular Diseases, Congenital Diaphragmatic Hernia
Respiratory Muscles and Work of Breathing in Children
Respiratory muscle testing allows a quantitative assessment of inspiratory and expiratory muscles in children of any age with primary or secondary respiratory muscle impairment, in order to better understand the pathophysiology…
- Conditions
- Neuromuscular Diseases, Congenital Diaphragmatic Hernia, Lung Diseases, Cardiac Diseases
- Trial name
- WOB&MR_Ped (NCT05051254)
- Testing
- Esogastric pressure measurement
- Where
- France
- Volunteers
- 550 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myofascial Pain Dysfunction Syndrome, Trigger Points, Myofascial
PRP vs PRP+Betamethasone vs Betamethasone Injection for Upper Trapezius Myofascial Pain
Brief Summary Myofascial pain syndrome (MPS) is a common musculoskeletal condition characterized by active trigger points (TrPs), which are hypersensitive, painful nodules within taut bands of skeletal muscle.
- Conditions
- Myofascial Pain Dysfunction Syndrome, Trigger Points, Myofascial, Trigger Point in Trapezius Muscle
- Trial name
- UMAY-RCT (NCT07547605)
- Testing
- Autologous Platelet-Rich Plasma (PRP), PRP plus Betamethasone, Betamethasone (Diprospan)
- Where
- 2 sites in Cyprus
- Volunteers
- 150 people
- Sponsor
- University of Kyrenia
Cognitive Decline, Sarcopenia
Holistic Integration for Healthy Longevity and Aging in Place
Background: Taiwan is experiencing rapid population aging, with a growing prevalence of chronic diseases and functional impairments among older adults.
- Conditions
- Cognitive Decline, Sarcopenia, Depression Disorders, Nutrition Disorder
- Trial name
- HIHOPE (NCT06882434)
- Testing
- Local intervention program, Referral Process, Telehealth Education & Digital Integration
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Mastication Disorder, Mandibular Dysfunction
Comparative Evaluation of Masticatory Efficiency of Implant Supported Overdenture
the goal of this clinical trial To evaluate the effects of different base materials of mandibular implant supported overdenture with bar/clip attachment on masticatory efficacy.
- Trial name
- NCT05877092
- Testing
- implants with overdentures
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Chronic Fatigue Syndrome, Cognitive Impairments
Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome
Over the past decade, the Rochester Center for Behavioral Medicine (RCBM) has evaluated many patients with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT01071044
- Testing
- Lisdexamfetamine Dimesylate
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rochester Center for Behavioral Medicine
Temporomandibular Disorder
Relationship Between Cervical Pain and Temporomandibular Dysfunction Craniovertebral Angle, Jaw Functional Limitation and Cervical Mobility
The aim of this study is to examine temporomandibular dysfunctions, jaw functional limitation, cervical mobility and craniovertebral angles and possible relations between individuals with cervical pain and individuals without…
- Trial name
- TMJ (NCT06623552)
- Testing
- Neck Pain and Disability Scale (NPDS), Fonseca Anamnestic Index (FAI), Evaluation of Jaw Functional Limitation
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Temporomandibular Joint Disorders
Treatment of Temporomandibular Dysfunction With Hypertonic Dextrose Injection
Dysfunction of the jaw, associated with pain in the jaw or about the jaw in the face can be quite long lasting and debilitating.
- Trial name
- NCT01617356
- Testing
- Injection of 20% dextrose/ 0.2% lidocaine, Injection of 1 ml of 0.8 SW/0.2% lidocaine
- Where
- Argentina
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Frusso, Ricardo, M.D.
Urinary Incontinence, Erectile Dysfunction
Effectiveness of Physiotherapy to Treat the Urinary Incontinence and Erectile Dysfunction Post Retropubic Prostatectomy
The prostate cancer is the most common parenchymal neoplasia in men over 45 years old. Radical prostatectomy is curative treatment is most used today.
- Trial name
- NCT02226237
- Testing
- group of pelvic floor exercises, anal electrostimulation group
- Where
- Brazil
- Volunteers
- 237 people
- Sponsor
- Barretos Cancer Hospital
Duchenne Muscular Dystrophy, Cardiomyopathies
The Preventive Efficacy of Carvedilol on Cardiac Dysfunction in Duchenne Muscular Dystrophy
Purpose This cardiac dysfunction in patients with Duchenne muscular dystrophy is associated with minor cardiac damage as indicated by elevation of plasma cardiac troponin I (cTnI).
- Trial name
- NCT00606775
- Testing
- Carvedilol
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Suzuka Hospital
Critical Illness, ICU Acquired Weakness
Muscle Evaluation Using Ultrasound in the Critically Ill
Critical illness is associated with ICU acquired weakness and diaphragmatic dysfunction. Ultrasound can evaluate the muscle mass non invasively and provides the ability for a muscle follow up during and after the ICU stay.
- Trial name
- ULTRAMUSCLE (NCT03550222)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Temporomandibular Joint Dysfunction Syndrome
Efficacy of Low Level LASER Therapy in Treating Temporomandibular Muscle Disorders
This study aimed to evaluate the sustainability of the efficacy of using low level laser therapy and CAD/CAM Michigan splint in improving the range of mandibular movements, muscle activity and reducing the pain.
- Trial name
- RCT (NCT05901701)
- Testing
- Low Level LASER therapy, Hard occlusal splint
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Ain Shams University
Abnormally Decreased Muscle Contraction
Abdominal Wall Evaluation in Low Back Pain
The purpose of this study was to evaluate feed-forward contraction of the transversus abdominis and thickness of the transversus abdominis, obliquus internus, and obliquus externus during calm and standardized respiration in low…
- Trial name
- NCT01488760
- Where
- Brazil
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Hematologic Diseases, Acute Myeloid Leukemia
Muscle Dysfunction in Patients With Haematological Diseases
PURPOSE: To evaluate the prevalence and prognostic value of sarcopenia in patients diagnosed with hematological cancer diseases.
- Conditions
- Hematologic Diseases, Acute Myeloid Leukemia, Acute Lymphoid Leukemia, Myelodysplastic Syndromes
- Trial name
- NCT05150561
- Where
- Denmark
- Volunteers
- 216 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Eustachian Tube Dysfunction
Eustachian Tube Dysfunction Assessment
The purpose of the study is to understand the exact mechanism of the activity of paratubal muscles in opening eustachian tube in patients with the functional eustachian tube and those with the eustachian tube dysfunction problem.
- Trial name
- ETDA (NCT02667301)
- Testing
- EMG recording, Tympanic Cavity Air Exchange Test, Tympanometer test
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Stratejik Yenilikci Girisimler Ltd.
Polycystic Ovary Syndrome, Hypothalamic Amenorrhea
Body Fat as Determinant of Female Gonadal Dysfunction
Reproduction requires from women enough energy depots to warrant an adequate nutritional supply to the fetus. Hence, adipose tissue is able to communicate with female hypothalamic-pituitary-ovary axis.
- Trial name
- NCT03841981
- Testing
- Anthropometric and physical examination, Indirect calorimetry, accelerometer and seven-day dietary recall, Biochemical, hormonal and metabolic phenotyping
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Urinary Dysfunction, Vaginal Prolapse
Effects of Kegel Ball and Pelvic Floor Exercises on Sexual Function, Unrınary Incontinence and Quality of Life in Women
Urinary incontinence and sexual dysfunction are common conditions that can significantly impact quality of life. Although surgical and medical treatments are available, many individuals seek non-invasive alternatives.
- Conditions
- Urinary Dysfunction, Vaginal Prolapse, Sexual Function Scores, Kegel Exercises
- Trial name
- NCT07048145
- Testing
- Vaginal Kegel Exercise Ball, Pelvic Floor Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- sahra sultan kara
Liver Diseases, Intra-Abdominal Hypertension
Organ Dysfunction Associated With Intra Abdominal Pressures in Liver Transplantation
Patients with end stage liver disease have varying degrees of intra-abdominal hypertension (IAH) due to the presence of ascites. The perioperative events may either relieve or aggravate the intra-abdominal pressures.
- Conditions
- Liver Diseases, Intra-Abdominal Hypertension, Cirrhosis, Liver, Organ Dysfunction Syndrome
- Trial name
- OIL (NCT04463745)
- Where
- India
- Volunteers
- 25 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Dyspareunia
Physiotherapy Intervention in Climacteric Women With Dyspareunia
Aim: To evaluate the effectiveness of physical therapy intervention techniques in the improvement of dyspareunia in climacteric women. Study design: This is a randomized controlled trial.
- Trial name
- NCT02804048
- Testing
- superficial heat pelvic floor muscle, superficial heat low back, Pelvic Floor Muscle Training
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Hospital de Clinicas de Porto Alegre