Clinical trials: Muscle Injury
Mechanical Ventilation
Use of Pressure Muscle Index to Avoid Over-assistance During Pressure Support Ventilation
Pressure support ventilation (PSV) is the most commonly used mode in mechanical ventilated patients. Studies have shown that over-assistance was prevalent in patients undergoing PSV.
- Trial name
- NCT05026463
- Testing
- Inspiratory support level
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- Capital Medical University
Burns
Comparison of Reversal of Neuromuscular Blockade With Sugammadex Versus Neostigmine Plus Glycopyrolate in Patients Undergoing Burn Surgery
The purpose of this study is to learn if there is a difference in recovery time when using sugammadex versus neostigmine. The researchers also hope to add further knowledge and data to the safety of using sugammadex in burn…
- Trial name
- NCT03513406
- Testing
- Sugammadex, Neostigmine, Glycopyrrolate
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Kansas Medical Center
Compartment Syndromes, Compartment Syndrome of Lower Leg
NIRST and ICG-based Perfusion Imaging in Acute Compartment Syndrome
This is a prospective observational study of patients with suspected Acute Compartment Syndrome. The primary objective of this work is to determine whether intensity changes associated with the NIRST signal, reflecting oxy- and…
- Conditions
- Compartment Syndromes, Compartment Syndrome of Lower Leg, Compartment Syndrome of Forearm
- Trial name
- NCT05672381
- Testing
- Lower extremity and/or upper extremity surgery
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Tennis Elbow
Effectiveness of Botulinum Toxin Injection in the Tennis Elbow Treatment
Some studies valued the effectiveness of botulinum toxin. Results are contradictory and we need more studies. The purpose of the study is to compare the effectiveness of botulinum toxin injection with placebo in the treatment of…
- Trial name
- TBA (NCT00437762)
- Testing
- Botulinum Toxin A Injection
- Where
- France
- Volunteers
- 61 people
- Sponsor
- University Hospital, Bordeaux
To Investigate the Change of Inter-joint Coordination and Muscle Activation in Patients With Cruciate Ligament Injury During Stair Negotiation.
Changes in Inter-joint Coordination and Muscle Activation After Cruciate Ligament Injury of the Knee Joint
Stair negotiation is an important activity of daily living. Patients with cruciate ligament injury may have difficulty in stair negotiation because of the proprioception deficit and neuromuscular deficit caused by ligament…
- Trial name
- NCT01584973
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lateral Epicondylitis, Tennis Elbow
Muscle Energy Technique Combined With Mulligan Technique in Tennis Elbow
This randomized controlled trial aims to evaluate the effectiveness of Muscle Energy Technique (MET) combined with Mulligan Mobilization With Movement (MWM) in patients with lateral epicondylitis (tennis elbow).
- Trial name
- NCT07604454
- Testing
- Muscle Energy Technique Combined With Mulligan Technique, Mulligan Mobilization With Movement
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Lahore
Lateral Epicondylitis
Effectiveness of Scapular Muscle Training in Improving Grip Strength Among Lateral Epicondylitis Patients
The effectiveness of scapular muscular training along with conventional physiotherapy on the improving the grip strength of the patients suffering with the lateral epicondylitis was assessed by diving 56 patinets in two grousp as…
- Trial name
- NCT06438328
- Testing
- Left/ Right affected arm, Grip strength
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Muhammad Naveed Babur
Perioperative Cardiavascular Complication, Peroperative Complication
Perioperative Management of Risk Factors in the Elderly Patients
In 2017, the number of operations on hospitalized patients in China was more than 57 million, of which more than 20 million were performed on elderly patients (≥65 years of age).
- Conditions
- Perioperative Cardiavascular Complication, Peroperative Complication, Perioperative Pulmonary Complication, Perioperative Neurological Complication
- Trial name
- NCT04967872
- Testing
- Implementing risk management and control plan for the elderly during perioperative period
- Where
- China
- Volunteers
- 4,782 people
- Sponsor
- Ailin Luo
Upper Extremity Dysfunction
Movement Enhancing Device for Children
The purpose of this study is to assess: 1) how infants move their bodies to explore, play, and solve problems, 2) if this is different in a high-risk group of infants, and 3) if these abilities can be advanced in a high-risk…
- Trial name
- NCT01959581
- Testing
- Movement Enhancing Device
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Muscle Spasticity
Safety and Preliminary Effectiveness of AV650 in Patients With Spasticity Due to Spinal Cord Injury
A drug called AV650 (tolperisone HCl) will be given to patients who have spasticity following a spinal cord injury. This study has three purposes: 1. To determine whether AV650 is safe for patients with spinal cord injury; 2.
- Trial name
- NCT00531466
- Testing
- tolperisone HCl (AV650)
- Where
- 10 sites in United States, Canada
- Volunteers
- 120 people
- Sponsor
- Avigen
Spinal Cord Injury
Blood Flow Restriction Exercise for Those With SCI
Spinal cord injuries (SCI) are among the most debilitating conditions an individual can sustain with the estimates of SCI incidence in the United States at 12,000 new cases per year.
- Trial name
- NCT04889092
- Testing
- Blood Flow Restriction exercise, Traditional resistance exercise
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Office of Research and Development
Brachial Plexus Birth Palsy, Brachial Plexus Palsy
Evaluation of Pain, Upper Extremity Function, and Social Appearance Anxiety in Adults With Obstetric Brachial Plexus Palsy Who Underwent Shoulder Tendon Transfer Surgery
This observational study aims to evaluate pain and upper extremity function in adults with obstetric brachial plexus palsy who underwent shoulder tendon transfer surgery using the Modified Hoffer technique during childhood.
- Conditions
- Brachial Plexus Birth Palsy, Brachial Plexus Palsy, Brachial Plexus Palsy Due to Birth Trauma
- Trial name
- NCT07655271
- Testing
- Clinical Assessment Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Biruni University
Wounds and Injuries, Compartment Syndrome
Closure of Fasciotomy Wounds: A Prospective, Observational Study of a Continuous External Tissue Expander
Fasciotomy wounds are rarely able to be closed at the time of index surgery. They often require multiple returns to surgery for closure, and occasionally require skin grafting (i.e. they are never completely closed).
- Trial name
- NCT01171534
- Testing
- DermaClose fasciotomy closure, Vessel loop
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Missouri-Columbia
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Reconstruction of the Anterior Cruciate Ligament of the Knee Joint, by the Method of Stabilization of the Screw With a Bioabsorbable Method, With or Without the Use of Autogenous Spongiform Bone Grafts.
Clinical and comparative evaluation of the results of autograft healing of the tendon of the semitendinus muscle in the tibial canal, after reconstruction of the anterior cruciate ligament of the knee joint, by the method of…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Knee Injuries
- Trial name
- NCT05328544
- Testing
- ACL reconstruction of the knee joint by arthroscopic technique, with the tibial fixation method using a bioabsorbable screw (Arthrex) with the use of autogenous cancellous bone grafts, ACL reconstruction of the knee joint by arthroscopic technique, with the tibial fixation method using a bioabsorbable screw (Arthrex) without the use of autogenous cancellous bone grafts
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- eMKa MED Medical Center
Rupture of Anterior Cruciate Ligament, Muscle Degeneration
Can Targeted Exercise Improve Knee Strength Following ACLR (RATE)
Anterior cruciate ligament reconstruction (ACLR) is high volume surgery, carried out in about 2800 patients annually in Denmark per year.
- Conditions
- Rupture of Anterior Cruciate Ligament, Muscle Degeneration, Gait, Unsteady
- Trial name
- RATE (NCT02939677)
- Testing
- Targeted exercise
- Where
- Denmark
- Volunteers
- 51 people
- Sponsor
- University of Southern Denmark
Geriatric Patients
Hohenheim Malnutrition Study in Geriatric Fracture Patients
The aim of this study is to evaluate long-term effects of early and prolonged individualized and optimized nutritional support using ONS for four weeks, in combination with a defined physiotherapy regimen, on sarcopenia and other…
- Trial name
- HohMal2 (NCT03493100)
- Testing
- oral nutritional supplementation, Usual care
- Where
- Germany
- Volunteers
- 106 people
- Sponsor
- University of Hohenheim
Amputation, Traumatic
The Relationship Between Thicknesses and Isokinetic Strength of Hip Flexor and Extensor Muscles
The aim of this study is to investigate the relationship of hip muscle thicknesses measured by ultrasonography with hip flexion and extension strength and clinical parameters in prosthesis users with unilateral traumatic…
- Trial name
- NCT05827744
- Testing
- Isokinetic evaluations, Ultrasonographic evaluations
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Impingement Shoulder, Impingement Syndrome
the Thickness of the Muscles and Pain in Impingement Syndrome
Pain intensity will be measured with visual analog scale. Sonographic severity grade of shoulder impingement syndrome, serratus anterior muscle, upper trapezius and middle trapezius will be measured with USG in patients diagnosed…
- Conditions
- Impingement Shoulder, Impingement Syndrome, Pain, Shoulder
- Trial name
- NCT06665139
- Testing
- muscle thickness
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Lateral Epicondylitis
Low and High Dose Dextrose Prolotherapy in the Treatment of Lateral Epicondylitis
Lateral epicondylitis (tennis elbow) is an enthesopathy seen in 1-2% of the population aged 30-65 years, which can occur in the lateral epicondyle origo of the extensor carpi radialis brevis and longus muscles, after frequently…
- Trial name
- NCT04680936
- Testing
- Dextrose 5% in water, Dextrose 15 % in Water, Isotonic sodium chloride solution
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Tendinopathy, Enthesopathy
Hyaluronic Acid Versus Platelet-Rich Plasma for Chronic Tendinopathy and Enthesopathy
Chronic tendinopathies and enthesopathies are common musculoskeletal conditions in orthopedics and sports medicine, frequently leading to pain, impaired function, and significantly reduced quality of life.
- Conditions
- Tendinopathy, Enthesopathy, Achilles Tendinopathy, Golfer's Elbow
- Trial name
- NCT07714811
- Testing
- Hyaluronic acid injection, Autologous Platelet-Rich Plasma Injection
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Ortonika Orthopedic Medical Clinic in Lublin