Clinical trials: Muscle Mass
Sarcopenia
Dietary Strategy to Tackle Sarcopenia in Early Elderly Subjects (FOOP-Sarc)
The main objective of the present study is to add knowledge of the potential health effects and mechanism of action by a dietary strategy based on a VOO rich in phenolic compounds (156 mg hydroxytyrosol and tyrosol/kg oil) alone…
- Trial name
- FOOP-Sarc (NCT05485402)
- Testing
- Refined olive oil (38.6 mg hydroxytyrosol and tyrosol/kg oil), Virgin olive oil rich in phenolic compounds (156 mg hydroxytyrosol and tyrosol/kg oil), Maltodextrin
- Where
- Spain
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Menopause Related Conditions, Exercise Training
Effects of Estrogen on Muscle Gain During 12-weeks of Exercise in Post-menopausal Women
As females age and transition through menopause, the decline in oestrogen level profoundly affects skeletal muscle mass and function.
- Trial name
- HER-MUSCLE (NCT07617454)
- Testing
- Estrogel, Physical exercise
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mette Hansen
Healthy Experienced Weight Training Males
The Effects of HMB, ATP, and HMB Plus ATP on Muscle Mass, Strength, and Power in Resistance Trained Athletes
The purpose of this study is to determine the effects of 12 weeks of HMB free acid gel, ATP, and HMB free acid gel plus ATP supplementation in trained individuals during a periodized training program on skeletal muscle…
- Trial name
- NCT01508338
- Testing
- HMB, Peak ATP and HMB, ATP
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Metabolic Technologies Inc.
Sarcopenia
A 24-week Off-drug Extension Study in Sarcopenic Elderly Who Completed Treatment in the 6-month Core Study
This extension study was a 24-week off-drug follow-up of the core CBYM338E2202 (NCT ) study and the main objective was to determine the long-term durability of bimagrumab (BYM338) effect after a 6-month treatment period.
- Trial name
- NCT02468674
- Testing
- bimagrumab
- Where
- 30 sites in United States, Australia and 10 more
- Volunteers
- 160 people
- Sponsor
- Novartis Pharmaceuticals
Sarcopenia, Cirrhosis
Muscle Mass Via UltraSound in Cirrhosis (MMUSCLE)
The goal of this observational cohort study is to learn about loss of muscle mass and muscle strength (sarcopenia) in patients with cirrhosis.
- Conditions
- Sarcopenia, Cirrhosis, Malnutrition
- Trial name
- MMUSCLE (NCT06345547)
- Testing
- ultrasound
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Hospital, Antwerp
Sarcopenia, Sarcopenia in Elderly
Effects of Aquatic Exercise in Older Adults With Sarcopenia:A Randomized Trial
Sarcopenia is a geriatric syndrome characterized by age-related loss of skeletal muscle mass, strength, and physical performance, leading to increased risk of falls, functional decline, and reduced quality of life.
- Trial name
- NCT07575958
- Testing
- Aquatic Exercise Program, Home Exercise Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Lean Body Mass
Does Muscle Mass At Intensive Care Unit Admission Determine Mortality: the Memo Study
This retrospective monocentric study aims to investigate whether a low muscle mass at ICU admission and its loss over the ICU stay predicts mortality, and in what proportion we can counteract it by nutritional support.
- Trial name
- MEMO (NCT05834894)
- Testing
- exposure(s) of interest : intensive care unit
- Where
- Switzerland
- Volunteers
- 4,000 people
- Sponsor
- University Hospital, Geneva
ACL Injury
Effects of HMB Supplementation on Recovery Following ACL Surgery
The anterior cruciate ligament (ACL) is a primary stabilizer of the knee, and thus when ACL injury occurs participation in physical activity is compromised.
- Trial name
- NCT02602561
- Testing
- HMB
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Metabolic Technologies Inc.
Rheumatoid Arthritis
The Effects Of Low Intensity Training With Blood Flow Restriction In Rheumatoid Arthritis Patients
Rheumatoid arthritis (RA) patients showed systemic manifestations that may lead to a reduction in muscle strength, muscle mass and, consequently, to a reduction in physical function.
- Trial name
- TBFR (NCT05869370)
- Testing
- High intensity resistance training, Low intensity resistance training combined with blood flow restriction
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Federal University of Rio Grande do Sul
Quadriceps Femoris Measurement as a Surrogate of Muscle Mass Assessment in Critically Ill Children
Ultrasound and MRI Measurement of Quadriceps Femoris Muscle in Critically Ill Children
A vast majority of children admitted to paediatric intensive care (PICU) present with faltering growth during their admission. Muscle mass loss is an early, intense and frequent phenomenon in this setting, which is associated…
- Trial name
- Echo-QF-IRM (NCT05108441)
- Testing
- Ultrasound and magnetic resonance imaging measurements of quadriceps femoris
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Hospices Civils de Lyon
Sarcopenia
RELIEF - Resistance Training for Life
Sarcopenia is an age-related gradual loss of muscle mass and strength and is associated with physical disability and mortality risk.
- Trial name
- RELIEF (NCT05063279)
- Testing
- Progressive resistance training
- Where
- Norway
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Stian Ellefsen
Out of Hospital Cardiac Arrest, Inhospital Cardiac Arrest
Skeletal Muscle Mass on Prognosis and Recovery in Clinical Trial
The objective of this research project is to develop an automated muscle mass measurement system based on computed tomography (CT) images using deep learning and artificial intelligence, and to construct a prognostic prediction…
- Trial name
- NCT07034170
- Testing
- Enhanced Rehabilitation Program
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Sarcopenia, Diabetes Mellitus
Glucose Metabolism, Muscle Mass/Function and Inflammation in the Elderly
A thorough characterization of glucose metabolism and "inflammaging" in elderly subjects will help determine to what extent each of these factors affects muscle mass/function and contributes to age-related muscle wasting.
- Trial name
- NCT02426073
- Where
- 2 sites in Italy
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Exercise, Nutrition Therapy
Effects of Whey Protein and Collagen Supplementation
The present project aims to investigate the effects of high-quality protein (whey protein) vs. low-quality protein (collagen) on muscle mass and function (e.g., strength and power) during a 10-wk resistance training program in…
- Conditions
- Exercise, Nutrition Therapy, Resistance Training, Muscle Strength
- Trial name
- NCT04213586
- Testing
- Whey protein supplementation, Collagen supplementation
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidade Norte do Paraná
Body Composition, Muscle Mass
EMS Combined With Resistance Training in Weight Lifters
The purpose of this randomized controlled trial is to determine the effects of Electrical Muscle Stimulation (EMS) combined with resistance training on muscle mass, muscular strength, body composition, and power in trained…
- Conditions
- Body Composition, Muscle Mass, Muscle Strength
- Trial name
- NCT07484646
- Testing
- EMS + Resistance Training, Resistance Training Only
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Tetraplegia/Tetraparesis, Rehabilitation Treatment
Efficacy of Robotic Upper Limb Rehabilitation Training in Patients With Tetraplegia
The goal of this clinical trial is to evaluate the efficacy of upper-limb robotic rehabilitation training (PABLO®) for recovering muscle strength in the scapulohumeral region and the proximal upper limb-compared to standard…
- Conditions
- Tetraplegia/Tetraparesis, Rehabilitation Treatment, Gaining Skeletal Muscle Mass and Strength
- Trial name
- TRRAT (NCT07860827)
- Testing
- Robotic Rehabilitation with PABLO®, Standard Gym Rehabilitation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Head and Neck Cancer Patients, Lean Body Mass
Lean Body Mass in Head and Neck Cancer Patients During Cisplatin-based Chemoradiation
The goal of this clinical trial is to investigate the changes in body composition in head and neck cancer patients during treatment.
- Conditions
- Head and Neck Cancer Patients, Lean Body Mass, Body Composition Changes
- Trial name
- NCT05890859
- Testing
- DXA scan, Physical testing
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Department of Public Health, Denmark
Low-Calorie Diet, Diet, High-Protein
The Effect of Diet Counseling for Low Calorie-High Protein on the Body Composition, Inflammation Marker, and Oxidative Stress Marker in Obese People With Weight Cycling
The world prevalence of obesity in adult population in 2014 was nearly 13% while in Indonesia, it has reached 32.9% in the same year. Obesity is an established risk factors for cardiovascular diseases.
- Conditions
- Low-Calorie Diet, Diet, High-Protein, Obesity; Pituitary, Weight Cycling
- Trial name
- NCT03374150
- Testing
- diet counseling
- Where
- 2 sites in Indonesia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia