Clinical trials: Muscle Mass, open to volunteers
Crohn Disease (CD)
Evaluation of Muscle Strength and Muscle Mass in Patients With Inflammatory Bowel Disease
This prospective observational study aims to evaluate the validity of ultrasonographic muscle measurements in patients with inflammatory bowel disease (IBD).
- Trial name
- IBDSARC (NCT07441447)
- Testing
- Muscle Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sakarya University
Lung Cancer, Sarcopenia
Impact of Fat-free Mass in the Carboplatin Calculated Dose and Chemotherapeutic Toxicity in Patients With Advanced NSCLC
This study evaluate the association of body composition (mainly free-fat mass), clinical and biochemical parameters with development of toxicity in patients under treatment with Carboplatin/Paclitaxel in advanced NSCLC.
- Conditions
- Lung Cancer, Sarcopenia, Toxicity
- Trial name
- NCT02734069
- Testing
- Carboplatin
- Where
- Mexico
- Volunteers
- 132 people
- Sponsor
- Instituto Nacional de Cancerologia de Mexico
Multiple Sclerosis, Sarcopenia
Investigation of the Prevalence of Sarcopenia and Dynapenia According to Disease Stage in Patients With Multiple Sclerosis and Evaluation of the Relationship Between Sarcopenia Severity and Clinical and Functional Parameters
This cross-sectional observational study aims to determine the prevalence of sarcopenia and dynapenia across disability stages in patients with multiple sclerosis (MS) and investigate their associations with clinical and…
- Conditions
- Multiple Sclerosis, Sarcopenia, Dynapenia
- Trial name
- MS-Sarcopenia (NCT07842731)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Atılım University
Type 2 Diabetes, Obesity
Impact of Semaglutide (Ozempic/Wegovy®) on Heart and Muscle Mass
The aim of this study is to use advanced MRI scans to track changes in both muscle and fat in the body and heart over a 12-month period in individuals starting semaglutide.
- Conditions
- Type 2 Diabetes, Obesity, Semaglutide, GLP-1
- Trial name
- GLIMMER (NCT07272837)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Metastatic Prostate Cancer
Creatine Supplementation and Resistance Training to Preserve Muscle Mass and Attenuate Cancer Progression
The goal of this clinical trial is to test the use of creatine monohydrate supplementation with resistance training to preserve muscle mass and help lessen prostate cancer progression.
- Trial name
- CREATINE-52 (NCT06112990)
- Testing
- creatine monohydrate, Home-based, telehealth
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Sarcopenic Obesity
Effectiveness of a Care Model for Sarcopenic Obesity in Older Adults on Fat Mass, Muscle Mass, Muscle Strength, and Physical Performance
Older adults
- Trial name
- NCT07523672
- Testing
- sarcopenic obesity modification programe
- Where
- Thailand
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Srinakharinwirot University
Nephrotic Syndrome
Ketoanalogues for Muscle Mass Loss in Nephrotic Syndrome
The goal of this non-commercial clinical trial is to assess efficacy and safety of ketoanalogues of essential amino acids in the prevention of protein-energy wasting in nephrotic syndrome.
- Trial name
- FORMA (NCT05716880)
- Testing
- Ketosteril, Medium Protein Diet (MPD)
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Military Institute od Medicine National Research Institute
Out of Hospital Cardiac Arrest, Inhospital Cardiac Arrest
Skeletal Muscle Mass on Prognosis and Recovery in Clinical Trial
The objective of this research project is to develop an automated muscle mass measurement system based on computed tomography (CT) images using deep learning and artificial intelligence, and to construct a prognostic prediction…
- Trial name
- NCT07034170
- Testing
- Enhanced Rehabilitation Program
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Glioblastoma Multiforme of Brain, Brain Cancer
The Impact of Resistance ExerciSe on Muscle Mass in GlioblaSToma Survivors
Glioblastoma patients are confronted with a debilitating disease associated with a low survival rate and poor quality of life. The goal of this study will be to reach a largely underrepresented population in the exercise…
- Trial name
- RESIST (NCT05116137)
- Testing
- Circuit-based resistance exercise (CRT)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Nova Scotia Health Authority
Sarcopenia in Elderly, Frailty at Older Adults
Effect of Micronized Creatine Monohydrate on Muscle Mass, Strength and Performance in Older Adults Submitted to Total Knee Arthroplasty
Double-blind randomized placebo-controlled clinical trial with two parallel arms. The main objective is to evaluate the efficacy and safety of creatine supplementation in older adults who have been operated on for total knee…
- Conditions
- Sarcopenia in Elderly, Frailty at Older Adults, Functional Capacity, Creatine Supplementation
- Trial name
- CREAR (NCT06925880)
- Testing
- Creatine Monohydrate
- Where
- Spain
- Volunteers
- 262 people
- Sponsor
- Consorci Sanitari del Maresme
Healthy Male Volunteers Over 65
Assessing the Impact of a Leucine Enriched Whey Protein vs Isonitrogenous Whey on Muscle Protein Synthetic Responses in the Rested and Acute Post Exercise States in Older Adults
Occupying ~45-55% of body mass, skeletal muscle is the largest organ of the body and plays a pivotal role in locomotion, structural support and whole-body metabolic health.
- Trial name
- NCT06971822
- Testing
- Protein Supplementation
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Adenopathy, Uterine Fibroids
A Clinical Study on the Feasibility and Safety of Abdominal Endoscopic Single-port Surgery System to Assist Gynecological Day Surgery
In this study, a prospective study is used to select patients who will undergo intra-abdominal endoscopic single-port surgery system for benign gynecological diseases from February 2025 to December 2026 in the Second Affiliated…
- Conditions
- Adenopathy, Uterine Fibroids, Ovarian Cysts, Adnexal Mass
- Trial name
- NCT06828419
- Testing
- Domestic single-port laparoscopic surgery system
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Healthy
Muscle Mass, Quality, and the Menopause: Sex-specific Strategies to Mitigate Sarcopenia in Ageing Populations
Aging causes muscles to often become smaller and weaker resulting in physical frailty and functional impairments, such as difficulty raising from a chair, dressing, and preparing meals.
- Trial name
- NCT06806501
- Testing
- Unilateral Resistance Exercise
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Overweight or Obesity, Physical Activities
An Innovative Care Model Integrating Mobile Health Support to Promote Weight Management in Adults With Overweight or Obesity
The objective of this clinical trial is to evaluate whether an innovative care model integrating mobile health (mHealth) support improves weight management in adults with overweight or obesity.
- Conditions
- Overweight or Obesity, Physical Activities, Healthy Diet, Weight Change
- Trial name
- NCT06996431
- Testing
- EMA-based weight management intervention, Minimal Intervention
- Where
- 3 sites in Hong Kong
- Volunteers
- 876 people
- Sponsor
- The University of Hong Kong
Muscle Mass, Obesity and Overweight
Calf Circumference Adjusted for Body Composition to Assess Muscle Mass
Muscle mass is a critical indicator for malnutrition and sarcopenia assessment. Anthropometric measurements like calf circumference (CC) could be a simple and cost-effective alternative when gold standard methods are not…
- Trial name
- NCT06829004
- Volunteers
- 150 people
- Sponsor
- University of Tartu
Sarcopenia
Magnesium Supplementation as a Nutritional Intervention in Sarcopenia
Sarcopenia is a progressive condition common in older adults and is characterized by loss of muscle strength, muscle mass, and physical performance.
- Trial name
- SARCOMAG (NCT07567963)
- Testing
- Citrate Magnesium Supplementation
- Where
- Portugal
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Saúde - Universidade do Algarve
Sarcopenia
Clinical Trial to Evaluate the Efficacy of Neuromuscular Electrical Stimulation Therapy in Patients With Sarcopenia
The goal of this clinical trial is to exploratorily evaluate the safety and efficacy of a home-based lower extremity muscle strengthening and physical performance enhancement program using Neuromuscular Electrical Stimulation…
- Trial name
- NMES (NCT07668258)
- Testing
- neuromuscular electrical stimulation
- Volunteers
- 40 people
- Sponsor
- Exosystems
Aging, Frailty
A Randomized Controlled Trial Comparing Whole Body Vibration Therapy With Usual Care and Usual Care to Improve Muscle Health in Older Adults
This study is a randomized controlled trial where participants would be randomly assigned to one of 2 groups. One group would receive Whole body vibration therapy and usual care and the other group only usual care.
- Conditions
- Aging, Frailty, Sarcopenia, Muscle Strength
- Trial name
- NCT07205133
- Testing
- Whole Body Vibration Training, Otago Exercise
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Obesity & Overweight, Diabetes (DM)
Determination of Resistance Training Status for Patients on Glucagon-Like Peptide-1 Receptor Agonists
This study examines how adults who take a GLP-1 receptor agonist medication (such as semaglutide [Ozempic, Wegovy, Rybelsus], liraglutide [Saxenda, Victoza], or tirzepatide [Mounjaro, Zepbound]) perform resistance (strength)…
- Trial name
- NCT07702461
- Testing
- Glucagon-Like Peptide-1 Agonist (GLP-1)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Ohio State University
Periprosthetic Knee Infection
Analysis of Pharmacological Aspects Regarding Infection Free Survival After Surgical Treatment of a Periprosthetic Knee Infection: a Microdialysis Study
This study aims to use the technique of microdialysis to analyse the intraarticular space of the knee joint after removal of a periprosthetic joint infection affected endoprosthesis and implantation of an antibiotic-containing…
- Trial name
- PJI_K_MD (NCT07299565)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bonn