Clinical trials: Muscle Mass and Strength, active
Hematologic Diseases, Chronic Myeloid Leukemia
Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant
PURPOSE: To investigate the effect of the disease and HSCT on muscle dysfunction and to investigate the prognostic role of muscle dysfunction at critical decision points in patients with hematological diseases referred to…
- Conditions
- Hematologic Diseases, Chronic Myeloid Leukemia, Acute Myeloid Leukemia, Acute Lymphoid Leukemia
- Trial name
- NCT04167683
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 144 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Primary Sjögren Syndrome, Sarcopenia
Possible Sarcopenia, Sarcopenia, and Functional Status in Patients With Primary Sjögren's Syndrome
The aim of this study is to evaluate the frequency of probable sarcopenia and sarcopenia in patients with primary Sjögren syndrome and to investigate the effects of sarcopenia on functional status, muscle strength, and quality of…
- Trial name
- NCT07804719
- Testing
- dexa, hand grip strength, myostatin, follistatin
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Mild Cognitive Impairment
Resistance Exercise Training in Individuals Aged 60 and Older With Mild Cognitive Impairment
The aging population in Chile and worldwide is increasing, with older people expected to represent 32.1% of the population by 2050.
- Trial name
- RET-MCI (NCT06470568)
- Testing
- Progressive Resistance exercise training
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Universidad de La Frontera
Sarcopenia
The Foods & Oil to Repair, Correct and Enhance Strength (FORCES) Study
The proposed research is a parallel arm, randomized placebo-controlled clinical trial designed to assess changes in muscle strength, volume, fatigue resistance, and mobility in older adults after daily consumption of 12g of…
- Trial name
- NCT06361511
- Testing
- High Linoleic Acid Foods, High Oleic Acid Foods
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Ohio State University
Heart Failure with Preserved Ejection Fraction (HFPEF), Heart Failure with Reduced Ejection Fraction
Feasibility and Effectiveness of Eccentric Exercise in Sarcopenic Older Adults with Heart Failure: a Pilot Study
This study is designed to evaluate the safety, feasibility, and effectiveness of a 12-week eccentric exercise program for older adults with sarcopenia (muscle loss) or sarcopenic obesity and chronic heart failure (HF).
- Conditions
- Heart Failure with Preserved Ejection Fraction (HFPEF), Heart Failure with Reduced Ejection Fraction, Sarcopenia in Elderly, Sarcopenic Obesity
- Trial name
- ECLYPSE-HF (NCT06826963)
- Testing
- Aerobic eccentric intervention
- Where
- 2 sites in Italy
- Volunteers
- 15 people
- Sponsor
- Universita di Verona
COPD, Quadriceps Muscle Atrophy
Clinimetric Properties of Muscle Mass and Stiffness Measurements of the Quadriceps in Patients With COPD
A large amount of patients with COPD suffer from muscle dysfunction characterized by losses of muscle mass and strength. Studies have shown an association between a loss of quadriceps muscle mass and premature death.
- Trial name
- Metriquad (NCT06994689)
- Testing
- Perimetry and ShearWave measurement of the quadriceps muscle before and after a pulmonary rehabilitation (PR) programme
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Groupe Hospitalier du Havre
Heart Failure
High-Protein Diet and HMB Supplementation in Patients With Heart Failure
The goal of this clinical trial is to evaluate the effects of a high-protein diet with or without HMB supplementation compared with a normoprotein diet on clinical, nutritional, and functional outcomes in patients with heart…
- Trial name
- NCT07731048
- Testing
- β-Hydroxy-β-Methylbutyrate (HMB), Individualized Dietary Counseling
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer
GALENOS 1 in Head and Neck, Lung, and Rectal Cancer Patients
GALENOS 1 is a prospective observational study designed to explore longitudinal changes in nutritional status and body composition in patients with head and neck squamous cell carcinoma, locally advanced rectal cancer, and lung…
- Conditions
- Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer, Lung Cancer
- Trial name
- GALENOS 1 (NCT07511413)
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Muscle Composition, Obesity
The Effects of Strength Training on Muscle Mass and Mental Health in Adults Taking Obesity Medication
The purpose of this study is to examine the effects of resistance exercise, such as weightlifting, on retention of muscle mass and mental health in individuals taking GLP-1 RAs (an obesity medication).
- Conditions
- Muscle Composition, Obesity, Quality of Life (QOL)
- Trial name
- STRONG (NCT07652333)
- Testing
- Resistance Exercise, GLP-1 RAs
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Spinal Cord Injury, Spinal Cord Injuries
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injury
- Trial name
- NCT04460872
- Testing
- Testosterone Enanthate, Locomotor Training
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- North Florida Foundation for Research and Education
Sarcopenia, Possible Sarcopenia
HB05P on Muscle Health
The purpose of this pilot study is to evaluate whether HB05P, a health functional food ingredient containing pasteurized Akkermansia muciniphila HB05, improves muscle strength, and to evaluate its safety.
- Trial name
- NCT07749118
- Testing
- HB05P
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Heart Failure, Sarcopenia
Multivariate Biomarker Study for Sarcopenia in Heart Failure
In the United Kingdom, heart failure (HF) affects about 900,000 people with 60,000 new cases annually. Up to 60% of people living with HF also experience sarcopenia, known as loss of muscle mass and strength.
- Conditions
- Heart Failure, Sarcopenia, Muscle Weakness, Body Weight
- Trial name
- NCT06217640
- Testing
- Dual X Ray Absorptiometry
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Prostate Cancer
The Effect of Pulsed Electromagnetic Field Therapy on Muscle Mass and Muscle Strength in Prostate Cancer Patients Treated With Androgen Deprivation Therapy
This study is to assess the effect of Pulsed electromagnetic fields (PEMF) on improving muscle mass and strength in prostate cancer patients with ADT.
- Trial name
- NCT07057375
- Testing
- Pulsed electromagnetic fields Thearpy
- Where
- Hong Kong
- Volunteers
- 110 people
- Sponsor
- Chinese University of Hong Kong
Physical Performance, Leg Muscle Mass
Lower-Limb Muscle Mass and Cardiovascular and Muscular Performance in Males and Females
The aim of this study will be to examine the relationship between leg muscle mass and muscle strength, aerobic capacity, anaerobic power, and jumping performance in young adults.
- Conditions
- Physical Performance, Leg Muscle Mass, Muscle Strength, Aerobic Capacity
- Trial name
- NCT07440615
- Testing
- Physical Performance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Uludag University
Obesity (Disorder)
Tirzepatide and Muscle Outcomes in Obesity
This study is evaluating whether a dual glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist, tirzepatide, can affect the function, structure and metabolism of skeletal muscles…
- Trial name
- TIRMO (NCT07373834)
- Testing
- Tirzepatide
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Sarcopenia, Sarcopenia in Elderly
Effects of Aquatic Exercise in Older Adults With Sarcopenia:A Randomized Trial
Sarcopenia is a geriatric syndrome characterized by age-related loss of skeletal muscle mass, strength, and physical performance, leading to increased risk of falls, functional decline, and reduced quality of life.
- Trial name
- NCT07575958
- Testing
- Aquatic Exercise Program, Home Exercise Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Endometrial Cancer
Metabolic Effect of Exercise and Diet in Endometrial Cancer Patients Eligible for Staging Surgery.
Background: Endometrial cancer is one of the diseases linked to obesity in women. In Mexico, about 7.6 women out of every 100,000 are diagnosed with this type of cancer, and nearly three-quarters of these women have obesity.
- Trial name
- NCT07025213
- Testing
- Diet and exercise., Diet.
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- National Institute of Cancerología
Crohn Disease (CD)
Evaluation of Muscle Strength and Muscle Mass in Patients With Inflammatory Bowel Disease
This prospective observational study aims to evaluate the validity of ultrasonographic muscle measurements in patients with inflammatory bowel disease (IBD).
- Trial name
- IBDSARC (NCT07441447)
- Testing
- Muscle Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sakarya University
Multiple Sclerosis, Sarcopenia
Investigation of the Prevalence of Sarcopenia and Dynapenia According to Disease Stage in Patients With Multiple Sclerosis and Evaluation of the Relationship Between Sarcopenia Severity and Clinical and Functional Parameters
This cross-sectional observational study aims to determine the prevalence of sarcopenia and dynapenia across disability stages in patients with multiple sclerosis (MS) and investigate their associations with clinical and…
- Conditions
- Multiple Sclerosis, Sarcopenia, Dynapenia
- Trial name
- MS-Sarcopenia (NCT07842731)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Atılım University
Sarcopenic Obesity
Effectiveness of a Care Model for Sarcopenic Obesity in Older Adults on Fat Mass, Muscle Mass, Muscle Strength, and Physical Performance
Older adults
- Trial name
- NCT07523672
- Testing
- sarcopenic obesity modification programe
- Where
- Thailand
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Srinakharinwirot University