Clinical trials: Muscle Morphology
Low Back Pain, Paraspinal Muscles
Effect of Neuromuscular Electrical Stimulation in Patients With Chronic Low Back Pain
This study evaluates the effect of a 10-week long intervention with the StimaWELL 120MTRS system on multifidus morphology and function in individuals with chronic low back pain.
- Trial name
- NCT04891692
- Testing
- StimaWell 120MTRS system
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Concordia University, Montreal
Anterior Knee Pain Syndrome
Knee Extensor Muscle Properties in Young Women Symptomatic and Asymptomatic for Anterior Knee Pain
This study aims to compare the knee extensors' mechanical, morphological and myoelectric properties between subjects affected by anterior knee pain and a healthy control group.
- Trial name
- NCT02734030
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Muscle Strength, Athletic Performance
Nordic vs Blood Flow Restriction Nordic Exercise in Elite Female Pole Vaulters
The purpose of this randomized controlled trial is to compare the effects of Nordic Hamstring Exercise (NHE) and Blood Flow Restriction-assisted Nordic Hamstring Exercise (BFR-NHE) on hamstring muscle strength, muscle morphology…
- Conditions
- Muscle Strength, Athletic Performance, Hamstring Adaptation, Sports Injury Prevention
- Trial name
- NCT07705698
- Testing
- Nordic Hamstring Exercise, Blood Flow Restriction-Assisted Nordic Hamstring Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Toros University
Neck Muscle Issue, Sternocleidomastoid; Contracture
Functional and Morphological Characteristics of Neck Muscles in Acrobatic Skydivers
An observational cohort study, following the Strengthening the Reporting of Observational Studies in Epidemiology(STROBE) guidelines.
- Conditions
- Neck Muscle Issue, Sternocleidomastoid; Contracture, Deltoid Muscle Strain
- Trial name
- NCT04784195
- Testing
- Observation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Fibroid, Leiomyoma
Novel MRI Strategies as a Non-invasive Biomarker in Women With Uterine Fibroids
Fibroids are present in up to 80% of women of reproductive age. Associated heavy menstrual bleeding is often an indication for surgery. At present there are no long-term medical treatments for fibroids.
- Trial name
- NCT00746031
- Testing
- GnRH analogue (Zoladex), GnRH antagonist-Cetrorelix
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Edinburgh
Urinary Incontinence
Postpartum Pelvic Floor Muscle Training in Women With and Without Injured Pelvic Floor Muscles
Although pregnancy and childbirth are associated with happiness and a positive life change for most women, it can also be considered as risk periods for injuries to the pelvic floor and development of pelvic floor dysfunction.
- Trial name
- NCT01069484
- Testing
- Postpartum pelvic floor muscle training
- Where
- Norway
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Hypertrophy, Contraction
Resistance Training Effects on Muscle Morphological, Mechanical and Contractile Properties
The aim of the research project is to investigate the influence of resistance-training prescription (repetition duration, time under tension and training volume) and sex have on morpho-functional adaptations of upper and…
- Trial name
- NCT04845295
- Testing
- resistance training
- Where
- Serbia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Tetraplegia
Electrical Stimulation in Denervated Muscles of the Upper Limbs
In the last decade the stimulation of denervated muscles got more attention. Not at least because of the promising results of the RISE project (Use of electrical stimulation to restore standing in paraplegics with long-term…
- Trial name
- NCT03698136
- Testing
- Stimulation of denervated muscles
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Spastic Cerebral Palsy (sCP)
Botulinum Neurotoxin for Children With CP: a Delicate Balance Between Clinical Benefits and Muscular Harm
A cross-sectional design study will be carried out to explore the morphological muscle properties and alterations in muscle composition on a macroscopic level in children with spastic cerebral palsy (CP).
- Trial name
- Bo-Balance (NCT06991725)
- Where
- Belgium
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Axial Spondylarthritis (axSpA), Myofascial Trigger Point Pain (MTrP)
Ultrasonographic Assessment of Thoracolumbar Fascia in AxSpA and Controls With Trigger Point Evaluation
The goal of this observational study is to evaluate whether changes in the thoracolumbar fascia (TLF)-a connective tissue in the lower back-are related to pain and disease severity in patients with axial spondyloarthropathy…
- Conditions
- Axial Spondylarthritis (axSpA), Myofascial Trigger Point Pain (MTrP), Ultrasound Exams
- Trial name
- NCT06978374
- Testing
- Sonographic examination of thoracolumbar fascia, manual examination of MTrP
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Ankara University
Myoma, Uterine Bleeding, Dysfunctional
Observation of Long-term Effects on Endometrium and Uterine Fibroids in Women With Ulipristal Acetate Therapy
A prospective observational study on italian women undergoing ulipristal acetate (uPa) therapy for symptomatic myomas and its impact on symptomatology and moreover on myomas architecture.
- Conditions
- Myoma, Uterine Bleeding, Dysfunctional, Uterine Bleeding Heavy, Dysmenorrhea
- Trial name
- NCT03972917
- Testing
- Transvaginal ultrasonographic examination
- Where
- Italy
- Volunteers
- 89 people
- Sponsor
- University of Campania Luigi Vanvitelli
Low Back Pain, Multifidus
Effects of Isolated Lumbar Extension Resistance Training Alone and in Combination with General Exercise and Manual Therapy
This study examines effects of machine-based isolated lumbar extension resistance exercise (ILEX) on paraspinal muscle morphology and function, as well as pain intensity, disability and quality of life in patients with chronic…
- Conditions
- Low Back Pain, Multifidus, Exercise Therapy, Diagnostic Imaging
- Trial name
- NCT06890052
- Testing
- Targeted exercise program, Targeted exercise as part of an integrative therapy program
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Wuerzburg
Back Disorder, Smartphone Addiction
Correlation Between Smartphone Addiction and Back Dysfunction and Core Muscle Morphology and Performance in Asymptomatic Young Adults
The purpose of this study is to investigate the association between smartphone addiction and back pain, function, and lumbar stabilizer cross-sectional area and thickness compared with non-addicted teenagers.
- Trial name
- NCT05321030
- Where
- Egypt
- Volunteers
- 136 people
- Sponsor
- Cairo University
Low Back Pain, Muscle Atrophy
Effect of a Supervised Exercise Program in Patients With Chronic Low Back Pain
This study evaluates the effect of a supervised exercise program on paraspinal muscle morphology and function, as well as disability/function in patients with non-specific chronic low back pain.
- Conditions
- Low Back Pain, Muscle Atrophy, Diagnostic Imaging, Exercise Therapy
- Trial name
- NCT04257253
- Testing
- Targeted exercise program, General exercise program
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Concordia University, Montreal
Patellofemoral Syndrome
Effect of Hip Adduction Combination With Knee Extension Exercise on Morphology of Quadriceps Muscles, Pain and Functional Outcomes in Patients With PFPS
Quadriceps retraining, especially the vastus medialis oblique muscle strengthening, plays an important role in clinical management of patellofemoral pain syndrome.
- Trial name
- NCT00166777
- Testing
- exercise training
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Obesity, Sarcopenia
Effectiveness of Combined GLP-1/GIP Dual Agonist Therapy and Structured Exercise on Skeletal Muscle Morphology, Quality, and Physical Function in Overweight and Obese Individuals
This randomized controlled trial aims to investigate the effects of a 24-week home-based progressive resistance exercise program combined with tirzepatide treatment on skeletal muscle mass, muscle quality, and functional capacity…
- Conditions
- Obesity, Sarcopenia, Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities
- Trial name
- NCT07609160
- Testing
- Resistance exercise, Lifestyle recommendations
- Volunteers
- 108 people
- Sponsor
- Acibadem University
Patellar Tendinopathy
Effects of Resistance Training on Patellar Tendon Properties in People With Patellar Tendinoapthy
This study aims to investigate the effects of two different resistance training interventions on the structural, morphological, mechanical, and functional properties of the thigh muscles (in particular the quadriceps femoris) and…
- Trial name
- PTGRAZ_26/27 (NCT07682051)
- Testing
- Eccentric Training, Heavy-Slow Resistance Training
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- University of Graz
Fibromyalgia Syndrome
The Efficacy of a Telerehabilitation Pilates Program in Fibromyalgia Syndrome Patients
The study aims to evaluate the effects of a telerehabilitation-based clinical pilates program in patients with fibromyalgia syndrome. A randomized controlled trial was designed.
- Trial name
- NCT06791954
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Chronic Low-back Pain, Muscle Atrophy
Effect of an Aquatic Exercise Program in Patients With Chronic Low Back Pain
The goal of this pilot randomized controlled trial is to compare the effects of aquatic therapy versus standard care on paraspinal and gluteal morphology and function in individuals with chronic low back pain.The main questions…
- Conditions
- Chronic Low-back Pain, Muscle Atrophy, Diagnostic Imaging, Exercise Therapy
- Trial name
- NCT05823857
- Testing
- Aquatic Therapy, Standard Care
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Concordia University, Montreal
Inclusion Body Myositis
IBM Dietary Surveillance Study
The goal of this observational study is to understand how diet may influence the disease characteristics of inclusion body myositis (IBM).
- Trial name
- NCT07535996
- Testing
- Whole-Body Dual-Energy X-ray Absorptiometry, Anthropometry, Capillary Blood Sampling
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University