Clinical trials: Muscle Rigidity
Erectile Dysfunction
the Diagnostic Value of Rigiscan Test (Nocturnal Penile Tumescence and Rigidity, NPTR) in Chinese Males
The purpose of this study is to evaluate the diagnostic value of Rigiscan (nocturnal penile tumescence and rigidity, NPTR ) test in erectile dysfunction of Chinese males.
- Trial name
- NPTR (NCT02573805)
- Testing
- Rigiscan test
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Dementia, Paratonia
Safety and Effectiveness of Botulinum Toxin in Elderly Patients With Dementia and Muscle Stiffness
Aim of the study is to perform a pilot study to assess the impact of Botulinum toxin on muscle tone, and caregiver burden in individuals who are cognitively impaired and who are fully dependent.
- Trial name
- NCT02212119
- Testing
- Botulinum Toxin, Saline
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Assistive Technology Clinic, Canada
Hepatic Transplantation
Evaluation of Hepatic Rigidity by Ultrasonic Impulse Elastography in Liver Transplant Patients
Interventional study with minimal risks and constraints, prospective, mono-centric.
- Trial name
- SUPERSONIC (NCT03174327)
- Testing
- Hepatic Transplantation
- Where
- France
- Volunteers
- 63 people
- Sponsor
- Rennes University Hospital
Cerebral Palsy, Hypertonia
Use of EMG to Assess Clinical Hypertonia
A handheld surface electromyography device will be tested by clinicians on children with limb hypertonia, and inter-rater reliability will be assessed with and without the device.
- Conditions
- Cerebral Palsy, Hypertonia, Spasticity, Dystonia
- Trial name
- NCT00472914
- Testing
- portable surface electromyography
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Southern California
Muscle Tone Abnormalities, Rigidity, Muscle
Neurophysiological Evaluation of Muscle Tone
The primary objective of this study is to apply a biomechanical system (the NeuroFlexor) associated with the EMG recording to study the physiological mechanisms that contribute to the regulation of muscle tone in healthy subjects…
- Conditions
- Muscle Tone Abnormalities, Rigidity, Muscle, Spasticity, Muscle
- Trial name
- NCT05070780
- Testing
- Robot-assisted examination
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Parkinson's Disease (PD)
Observational Study Evaluating Robotic Spinal Mobilization in 16 Parkinson's Disease Participants. The Study Recorded Changes in Mobility, Sit-to-stand Performance, and Pain Scores After a 2-week Intervention With the BackHug Device.
The goal of this completed observational pilot study was to evaluate the immediate and short-term clinical effects of robotic spinal mobilization on motor and non-motor symptoms in community-dwelling adults with Parkinson's…
- Trial name
- NCT07384364
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- Pacla Medical Limited
Movement Disorders, Parkinson's Disease
A Study of Movement Disorders Using the QMAT At-Home Testing Device
Background: Parkinson s disease (PD) affects half a million Americans, causing slow movements, tremors, stiffness, and trouble walking.
- Trial name
- NCT01905839
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Microlaryngoscopy, Rigid Bronchoscopy
Use of Sugammadex for Reversal of Paralysis in Microlaryngoscopy
Use of Muscle relaxant and reversal with Sugammadex at end of airway procedures will reduce the time to extubation after end of procedure
- Trial name
- NCT03111121
- Testing
- Sugammadex, neostigmine, glycopyrrolate
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Erectile Dysfunction
TRIP-Patch vs the Rigiscan
In men without erectile problems, night time erections occur during the REM-sleep. For this study the current diagnostic test, the Rigiscan is compared, with the data from the TRIP-Patch during the night.
- Trial name
- TRIP-Patch (NCT05219071)
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital
Parkinsons Disease
First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD)
This study is researching an experimental drug called ALN-SNCA (called "study drug"). The study is focused on people with early Parkinson's disease, a disorder of the nervous system that affects movement.
- Trial name
- NCT07216066
- Testing
- ALN-SNCA
- Where
- 3 sites in Canada, Netherlands
- Volunteers
- 46 people
- Sponsor
- Regeneron Pharmaceuticals
PARKINSON DISEASE (Disorder), Rigidity
Spinal Mobility, Rigidity, and Kinesiophobia in PD and TMD
Axial rigidity and loss of spinal mobility commonly observed in Parkinson's disease (PD) lead to postural deformities and substantial reductions in trunk flexibility.
- Conditions
- PARKINSON DISEASE (Disorder), Rigidity, Temporomandibular Disorders (TMDs), Mobility
- Trial name
- NCT07850674
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Anesthesia
Succinylcholine or Rocuronium for Rigid Bronchoscopy Under General Anesthesia
Myorelaxation is generally used as a part of general anesthesia for interventional rigid bronchoscopy. Succinylcholine is most often used because its short duration of action but rocuronium can be used since sugammadex permits a…
- Trial name
- Broncho-SR (NCT01579864)
- Testing
- succinylcholine, rocuronium
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Hopital Foch
Parkinson Disease
Effects of Whole Body Vibration in Parkinson's Disease Symptoms
The goal of this clinical trial is to know the effects of an intervention in Parkinson's disease symptoms. The main question it aims to answer are: Is whole body vibration able to reduce rigidity in Parkinson's participants? Can…
- Trial name
- NCT05621031
- Testing
- Whole body Vibration, Habitual Therapy
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- University of Seville
Articular; Rigid
Physiotherapeutic Case Studies in Frozen Shoulder Pathology
The stiff shoulder presents symptoms such as pain, loss of mobility and strength, being more common the idiopathic origin associated to the female gender.
- Trial name
- CH-Case (NCT05175586)
- Testing
- First data analysis, Second data analysis, database
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- GEMA LEÓN BRAVO
Cleft Palate
Comparison of Different Feeding Appliances for Cleft Palate Babies
This study will compare flexible , rigid feeding plates and a special feeding bottle for children with cleft palate.
- Trial name
- NCT06103162
- Testing
- flexible feeding plate
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Dementia, Gait
Fine and Gross Motor Function and Relationship With Muscle Tone in Older Adults With and Without Dementia
The purpose of this study was (1) to investigate changes in gait, balance, fine motor function, and muscle tone, and (2) to find out if there is a correlation between muscle tone/presence of paratonia and motor function (gross…
- Conditions
- Dementia, Gait, Balance, Muscle Tone
- Trial name
- NCT03479567
- Testing
- Gait accelerometry, balance accelerometry, Fine motor skill test
- Where
- Belgium
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University Ghent
Cough
Effect of Magnesium on Remifentanil Induced Cough
The hypothesis of this study is that Magnesium sulfate pretreatment (50mg/kg) will reduce the incidence of cough and chest wall rigidity caused by remifentanil administration.
- Trial name
- NCT05237791
- Testing
- Magnesium sulfate
- Volunteers
- 78 people
- Sponsor
- Seoul National University Bundang Hospital
Chronic Kidney Disease Requiring Chronic Dialysis, Cardiovascular Calcification
The Intravenous Amino Acid Therapy for Vascular Rigidity in End Stage Renal Disease
The goal of this study is to learn if giving amino acids through the dialysis machine can help protect the blood vessels and heart in people with kidney failure.
- Trial name
- NASCAR (NCT07392697)
- Testing
- Amino Acid Supplementation, Sterile Saline Arm
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Haukeland University Hospital
Dementia, Paratonia
Short-term Effect of Positioning Cushions and Harmonic Techniques on Paratonia in Persons With Dementia
This study investigated the short-term effect of both harmonic techniques and supporting cushions on muscle tone, range of motion, pain and daily care activities in 22 patients with moderate to severe paratonia.
- Trial name
- NCT03538405
- Testing
- Supporting cushions, Harmonic techniques
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- University Ghent
COPD
The Effects of Different Physiotherapy Approaches in Stable COPD Patients.
In our study, the effects of Kinesio Taping (KT), Rigid Taping (RT), Thoracic Mobilization (TM) and Core Stabilization (KS) approaches on respiratory muscle morphology, respiratory muscle strength, exercise capacity and quality…
- Trial name
- NCT05335304
- Testing
- intervention group 1, intervention group 2, intervention group 3
- Volunteers
- 65 people
- Sponsor
- Muğla Sıtkı Koçman University