Clinical trials: Muscle Rigidity
Glaucoma, Primary Open Angle Glaucoma
Changes in Ocular Rigidity After Trabeculectomy in Patients With POAG
It has been hypothesized that the biomechanical properties of the optic nerve head and/or sclera play a role in the development of glaucoma.
- Conditions
- Glaucoma, Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma
- Trial name
- NCT02544646
- Testing
- Changes in Ocular rigidity
- Where
- Austria
- Volunteers
- 53 people
- Sponsor
- Medical University of Vienna
MDC1A, SELENON-related Myopathy
The Natural History of Patients With Mutations in SEPN1 (SELENON) or LAMA2
SEPN1 (SELENON) is a rare congenital myopathy due to mutations in the SELENON gene. MDC1A is a rare congenital muscle dystrophy due to mutations in the LAMA2 gene.
- Trial name
- NCT04478981
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 38 people
- Sponsor
- Radboud University Medical Center
Osteoporosis
Arteos II Study: Relationship Between Osteoporosis and Arterial Rigidity Within Fractured Patients Cohort
The investigators planned to study relationship between osteoporosis and arterial rigidity within fractured patients cohort.
- Trial name
- ARTEOS2 (NCT01587456)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Central Hospital, Nancy, France
Toxicant Exposure, Firefighter
Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)
This randomized, placebo-controlled crossover trial will test the feasibility and acceptability of using colesevelam in male firefighters with high per- and polyfluoroalkyl substances (PFAS) exposure.
- Conditions
- Toxicant Exposure, Firefighter, Occupational Exposure to Chemicals
- Trial name
- ENGINE (NCT07226440)
- Testing
- Colesevelam
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Glaucoma
The Effect of Selective Laser Trabeculoplasty (SLT) on Ocular Rigidity
The purpose of this study is to examine the influence of selective laser trabeculoplasty (SLT) on ocular rigidity in glaucoma patients.
- Trial name
- SLT/ORA (NCT01247831)
- Testing
- Selective Laser Trabeculoplasty
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Technische Universität Dresden
PARKINSON DISEASE (Disorder)
Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms
This study tests a new, non-invasive brain stimulation device called Sphere V3.0 to help improve movement problems in people with Parkinson's disease.
- Trial name
- NCT07182058
- Testing
- Transcranial Electrical Stimulation Device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- U: The Mind Company
Cardiovascular Diseases
Vytorin on Carotid Intima-media Thickness and Overall Rigidity
Comparison of the effect on the progression of the carotid intima-media interphase thickness (GIM), arterial rigidity according to the measurement of the pulse wave speed and direct measurement of the carotid and aortic…
- Trial name
- VYCTOR (NCT00738296)
- Testing
- ezetimibe (+) simvastatin, simvastatin, pravastatin
- Volunteers
- 90 people
- Sponsor
- Hospital Universitario 12 de Octubre
Erectile Dysfunction
TRIP-patch vs Duplex
To measure saturation and desaturation of the cavernosal tissue with a cutaneous placed penile sensor, before and during full rigidity.
- Trial name
- NCT06402097
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- St. Antonius Hospital
Temporomandibular Disorder
Analysis of the Effects of the Osteopathic Manipulative Treatment in Carriers of Temporomandibular Disorders
The purpose of this study is to determine whether osteopathic manipulative treatment associated to Dentistry care and speech therapy improves pain and function in individuals with temporomandibular disorders.
- Trial name
- NCT02974166
- Testing
- Conventional Group, Osteopathic Group, Ibuprofen
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Instituto Brasileiro de Osteopatia
Parkinson Disease, Tremor, Limb
Effects of a Dynamic Upper Limb Orthosis in Patients With Parkinson's Disease
This is a randomized controlled clinical trial aimed at Parkinson's disease patients. Its objective is to evaluate the effects of a dynamic upper limb orthosis to achieve maximum hand functionality, reducing tremor and rigidity
- Conditions
- Parkinson Disease, Tremor, Limb, Rigidity, Muscle
- Trial name
- NCT04815382
- Testing
- Dynamic Upper Limb Orthosis
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Burgos
Myocardial Infarction, Acute, Myocardial Strain
Assessment of the Effects of Long-term Lipid-lowering Therapy in Patients With Primary STEMI or NSTEMI
In a single-center, open-label, prospective, controlled, clinical study, it is planned to include 300 patients hospitalized in the cardiology department of SBHI Penza regional clinical hospital n.a. N.N. Burdenko.
- Conditions
- Myocardial Infarction, Acute, Myocardial Strain, Arterial Stiffness, Quality of Life
- Trial name
- CONTRAST-2 (NCT04347434)
- Testing
- Atorvastatin 80mg
- Where
- Russia
- Volunteers
- 300 people
- Sponsor
- Penza State University
Erectile Dysfunction Following Radical Prostatectomy, Urinary Incontinence of Non-organic Origin
Viberect Penile Vibratory Stimulation to Enhance Recovery of Erectile Function and Urinary Continence Post-Prostatectomy
The purpose of this study is to evaluate whether using penile vibratory stimulation with the Viberect handheld device can help the recovery of erections and urinary control after radical prostatectomy.
- Trial name
- NCT01718704
- Testing
- Viberect device
- Where
- 2 sites in United States
- Sponsor
- Johns Hopkins University
Muscle Weakness
The Effect of Dynamic and Rigid Tape Application on the Asymmetry of the Lower Limbs
This is a prospective randomized three brachial, single-blinded, placebo-controlled trial, which aims at assessing the impact of the gluteal muscle taping with a dynamic tape and a non-elastic tape on the activation of the…
- Trial name
- NCT04345224
- Testing
- Dynamic tape, Rigid tape
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- John Paul II University in Biała Podlaska
Muscle Rigidity, Spasm
Intravenous Immunoglobulin (IVIg) for the Treatment of Stiff-Man Syndrome (SMS)
Stiff-man Syndrome (SMS) is a chronic, progressive disorder of the nervous system. It is associated with painful muscle spasms and rigidity involving muscles of the limbs, trunk, and neck.
- Conditions
- Muscle Rigidity, Spasm, Stiff Man Syndrome
- Trial name
- NCT00001550
- Testing
- IVIg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Pain, Muscle Rigidity
Investigation on a Topical Cosmetic Pain Lotion (Egyfil) for Stiffness and Pain Relief
The application of a novel topical formulation for the treatment of muscular pain and stiffness (Egyfil), containing hyaluronic acid, SH-Polypeptide-6 and SH-Oligopeptide-1, is investigated to evaluate efficacy and safety in 26…
- Trial name
- NCT05711953
- Testing
- Egyfil Pain Lotion
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Contrad Swiss SA
Flatfoot
Foot Positions Affect Knee and Ankle Proprioception, Balance, Vertical Jump, and Muscle Activity in Individuals With Flexible and Rigid Flatfoot and Chronic Ankle Instability
To investigate the effect of various foot positions affect knee and ankle proprioception, balance, vertical jump, and muscle activity in individuals with flexible and rigid flatfoot and chronic ankle instability
- Trial name
- NCT05899855
- Testing
- No intervention
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Parkinson Disease
A Multifactorial Exercise Program to Reduce Falls in People With Parkinson Disease
The primary objective of this study is to investigate the effects of a theoretically driven, highly challenging exercise program (balance and strengthening exercises) in reducing fall rate, improving balance and reducing fear of…
- Trial name
- NCT02302144
- Testing
- Balance & Strengthening Exercises
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Boston University Charles River Campus
Parkinson Disease
Effects of Deep Brain Stimulation on Motor, Mood, and Cognitive Symptoms in Parkinson's Disease
The purpose of this trial is to study the mood and cognitive effects of deep brain stimulation in Parkinson's disease.
- Trial name
- NCT00360009
- Testing
- DBS of the STN, DBS of the GPI
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Florida
Biceps, Muscle Rigidity
Blood Flow Technique Effect on the Muscle Mechanics
This study will be a study in which we take measurements with the myotonPRO device to determine whether the resistant exercises performed without the blood flow restrictive technique and with the blood flow restrictive technique…
- Trial name
- NCT06861699
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Okan University
Depression
Cognitive and Affective Processes Online
This study will provide data for evaluating the psychometric characteristics of the tests assessing cognitive flexibility, including their (1) internal consistency, (2) feasibility and tolerability, their (3) convergent and…
- Trial name
- NCT05736471
- Testing
- Computational dissociation of the causes of cognitive rigidity in depression
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota