Clinical trials: Muscle Rupture
Achilles Tendon Rupture
Impact of Achilles Tendon Rupture on the Achilles Tendon and Calf Muscles
The aim of this study is to measure the recovery following Achilles tendon rupture. The investigators will use an ultrasound scan to look at the Achilles tendon, they will complete calf strength tests and use questionnaires to…
- Trial name
- ARCH (NCT05683080)
- Testing
- Routine Clinical Care
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Leicester
Sciatic Leg Pain, Hamstring Muscle Tightness
Acute Effects of Neurodynamics on Strength and Endurance in Athletes
This study explores the acute effects of neurodynamics, an intervention commonly used by physical therapist to improve nerve mobility and decrease pain, on the strength and muscular endurance in the athletic population.
- Conditions
- Sciatic Leg Pain, Hamstring Muscle Tightness, Hamstring Muscle Strain, Hamstring Muscle Strength
- Trial name
- NCT07721220
- Testing
- Sciatic Slider, Sciatic Tensioner, Mechanically loaded neurodynamic sciatic floss
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- High Point University
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction
Clinical and Functional Outcomes After ACL Reconstruction Versus Primary Repair
The anterior cruciate ligament (ACL) is the primary structure responsible for controlling anterior-posterior translation and rotational stability of the knee joint.
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction, Isokinetic Test
- Trial name
- NCT07318272
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gazi University
Muscle Weakness, Anterior Cruciate Ligament Rupture
Does Gabapentin Reduce Quadriceps Muscle Weakness After Anterior Cruciate Ligament Reconstruction?
Anterior cruciate ligament (ACL) injury is a common sport injury in both professional and recreational athletes. Furthermore, persistent quadriceps weakness and wasting are frequently observed after anterior cruciate ligament…
- Trial name
- NCT03496389
- Testing
- Gabapentin, Tramadol, Panadol
- Volunteers
- 30 people
- Sponsor
- Hospital Authority, Hong Kong
Rupture of Anterior Cruciate Ligament
Biomechanical Analysis of Dynamic Tasks and Muscular Strength Following Anterior Cruciate Ligament Reconstruction
Background Anterior cruciate ligament (ACL) injuries are one of the most common sporting injuries of the knee. ACL reconstruction (ACLR) has become one of the most common surgical procedures in an attempt to increase joint…
- Trial name
- NCT02771548
- Testing
- Anterior Cruciate Ligament Reconstruction
- Where
- Ireland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Dr Neil Welch ASCC
Rotator Cuff Tears, Tendon Thickening
Perianchor Cyst Formation, Tendon Healing, and Clinical Outcomes Following Arthroscopic Rotator Cuff Repair
Perianchor cyst formation is frequently observed after arthroscopic rotator cuff repair; however, its clinical significance remains unclear.
- Conditions
- Rotator Cuff Tears, Tendon Thickening, Tendon Injuries, Muscle Weakness
- Trial name
- NCT07661680
- Testing
- MRI
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Childbirth
A Clinical Phase II Study of the Materna Device to Shorten Delivery Time During Childbirth
This feasibility study is a prospective, non-randomized, single arm study to evaluate safety and prevention of maternal pelvic soft-tissue damage using the Materna Medical Device.
- Trial name
- NCT06698185
- Testing
- Materna Prep Device
- Where
- United States
- Sponsor
- Materna Medical
Rotator Cuff Injuries, Rotator Cuff Repair Rehabilition
Efficacy of Adding Early Scapular Muscles Strengthening Exercise After Rotator Cuff Repair on Scapula Kinematics
The study investigates the effect of accelerate rehabilitation protocol(adding scapular strengthen exercises (lower trapezius and serratus anterior) from week 1) after arthroscopic rotator cuff repair on scapular upward rotation…
- Conditions
- Rotator Cuff Injuries, Rotator Cuff Repair Rehabilition, Supraspinatus Tear
- Trial name
- NCT06851650
- Testing
- Rehabilition protocol after rotator cuff repair surgery
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Muscle Tear
Registry of Celution Device for Processing ADRCs and Healing in Muscle and Ligament Sports Injuries
This registry study will compile information about patients who are scheduled to receive or have received Adipose Derived Regenerative cells (ADRCs) prepared by Celution device to treat muscle and ligament sports injuries.
- Trial name
- ACHILLES (NCT02770755)
- Where
- United Kingdom
- Sponsor
- Cytori Therapeutics
Pelvic Floor; Rupture, Old (Postpartum)
Correlation Between Creatine Phosphokinase and Pelvic Floor Muscle Strength in Postnatal Women
The purpose of this study is to determine the correlation between creatine phosphokinase and pelvic floor muscle strength in post-partum women.
- Trial name
- NCT06502392
- Testing
- Assessment of creatine phosphokinase, Assessment of pelvic floor muscle strength
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Cairo University
Arthritis, Osteoarthritis
The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study
Adolescents and young adults who hurt their knees playing sports or doing recreational activities can develop joint damage, muscle weakness, inactivity, and weight gain which might lead to an increased risk of osteoarthritis…
- Conditions
- Arthritis, Osteoarthritis, Arthritis Knee, Osteo Arthritis Knee
- Trial name
- SOARPOC (NCT04956393)
- Testing
- Immediate 8-Week SOAR Program, Delayed 8-Week SOAR Program
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Rotator Cuff Tear
Assessment of Muscle Function and Size in Older Adults With Rotator Cuff Tear
Adequate upper limb function is critically important to maintenance of independence and prevention of disability in older adults.
- Trial name
- ARC (NCT01459536)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Delivery; Trauma, Pelvic Floor; Perineal Rupture, Obstetric
Perineal Preparation for Pregnant Ladies.
Pregnant participants will be recruited at the obstetrics outpatient clinic during their visits 4 weeks before the due date. They are randomized into two groups. The first group will be educated to do digital perineal massage.
- Conditions
- Delivery; Trauma, Pelvic Floor; Perineal Rupture, Obstetric, Pelvic Floor Muscle Weakness
- Trial name
- NCT03287258
- Testing
- 3 program, one program
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Rotator Cuff Tendinosis
Blood Flow Restriction Training in Patients With Shoulder Pain
This study was planned to investigate the effect of blood flow restriction exercise training on shoulder muscle strength and muscle thickness, and to determine the change in pain and symptoms in patients with rotator cuff…
- Trial name
- NCT04333784
- Testing
- Exercise training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Hacettepe University
Rotator Cuff Tears, Muscle Atrophy or Weakness
E-CEL UVEC Cells as an Adjunct Cell Therapy for the Arthroscopic Rotator Cuff Repair in Adults
This is a phase 1b investigator-initiated clinical trial that will evaluate the safety and feasibility of E-CEL UVEC® cells with the aim of improving outcomes for patients with full-thickness rotator cuff tears who undergo…
- Conditions
- Rotator Cuff Tears, Muscle Atrophy or Weakness, Tendon Rupture - Shoulder, Safety Issues
- Trial name
- NCT04057833
- Testing
- E-CEL UVEC
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hospital for Special Surgery, New York
Rotator Cuff Tears, Rotator Cuff Injuries
Rotator Cuff Tear Severity and Scapular and Rotator Cuff Muscle Activation Patterns
Rotator cuff tears are common musculoskeletal injuries that can lead to altered scapular and rotator cuff muscle activation patterns and reduced function.
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Shoulder Pain
- Trial name
- NCT05946343
- Testing
- Surface Electromyography (sEMG) Assessment
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ahram Canadian University
Rotator Cuff Tears
Motions of the Bones and Activation of the Muscles of the Shoulder Girdle During Basic and Common Arm Movement
A comprehensive understanding of healthy shoulder motion is a valuable contribution to the academic literature and provides a basis of comparison for various shoulder pathologies and treatments.
- Trial name
- NCT04571268
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- More Foundation
Lateral Epicondylitis, Tennis Elbow
The Effect of Tendon Tears on Lateral Epicondylitis
Common extensor tendon (CET) tears that can be detected with ultrasonography (US) may be associated with worsening clinical and other ultrasonographic parameters in patients with LE.
- Conditions
- Lateral Epicondylitis, Tennis Elbow, Tendon Tear
- Trial name
- NCT06206109
- Where
- Turkey (Türkiye)
- Volunteers
- 227 people
- Sponsor
- Dokuz Eylul University
ACL Tear, ACL-injury
Do Patients With ACL Tears Demonstrate Weakness of the Soleus Muscle?
The goal of this prospective, cross-sectional study is to test the strength of the soleus muscle in participants who have a ACL tear confirmed by MRI.
- Conditions
- ACL Tear, ACL-injury, ACL - Anterior Cruciate Ligament Rupture
- Trial name
- ACL (NCT06235736)
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Meniscus Tear
Influence of Kinesio Tapping on Quadriceps Muscle Peak Torque and Bioelectrical Activity After Meniscectomy
A Pretest post-test control group design will be used to investigate the effect of kinesio taping on electrical activity and peak torque of the quadriceps femoris muscle during concentric and eccentric contraction after…
- Trial name
- NCT05715177
- Testing
- Cura Kinesio-taping
- Where
- Saudi Arabia
- Volunteers
- 132 people
- Sponsor
- University of Jazan