Clinical trials: Muscle Rupture
Shoulder Impingement Syndrome, Rotator Cuff Injuries
The Role of Pectoralis Minor Tightness in the Development of Rotator Cuff Tears
This study investigates whether tightness of a small chest muscle called the pectoralis minor is associated with the development of partial rotator cuff tears in the shoulder.
- Conditions
- Shoulder Impingement Syndrome, Rotator Cuff Injuries, Pectoralis Minor Tightness, Pectoralis Minor Muscle Tension
- Trial name
- PMinor-Rotator (NCT07228936)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gazi University
Rotator Cuff Tear, Muscle Atrophy
Stromal Vascular Fraction Cell Therapy to Improve the Repair of Rotator Cuff Tears
Rotator cuff disease is one of the most prevalent musculoskeletal conditions across the world. Patients with chronic rotator cuff tears often have substantial muscle atrophy and fatty infiltration.
- Conditions
- Rotator Cuff Tear, Muscle Atrophy, Tendon Tear
- Trial name
- NCT03332238
- Testing
- Autologous Stomal Vascular Fraction Material, Ringer's solution
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Hospital for Special Surgery, New York
Muscle Tear, Hand Injuries
Hand Therapy Approach on Lumbrical Muscle Tears in Sport Climbers
This study aimes to analyze the effectiveness of a Hand Therapy protocol in the management of patients who suffer from a tear of a lumbrical muscle, regarding on the symptoms during the clinical examination, the disability in…
- Conditions
- Muscle Tear, Hand Injuries, Splints
- Trial name
- NCT05694078
- Testing
- Hand Therapy Splinting Protocol
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hand Therapy Barcelona
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
Vitamin D to Improve Quadricep Muscle Strength
Quadriceps muscle strength is one of the key determinants for patients to fulfill the Return-to-Play (RTP) criteria after an anterior cruciate ligament reconstruction (ACLR), in which the muscle size is directly linked to muscle…
- Conditions
- Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT05174611
- Testing
- Vitamin D3
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Hamstring Injury, Muscle Rupture
Effect of NMES+ on Hamstring Lesion (3a/3b)
The goal of this clinical trial is to analyze the effect of the electrical stimulation superimposed onto movement in healthy semi-professional athletes who sustained a type 3a/3b hamstring strain injury.
- Conditions
- Hamstring Injury, Muscle Rupture, Hamstring Sprain
- Trial name
- NCT05786300
- Testing
- NMES+, Rehab
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Università degli studi di Roma Foro Italico
Rotator Cuff Tear
Did MRI Appearance of Supraspinatus Muscle Atrophy Changes After Repair of All Kind of Rotator Cuff Tear?
There are two purpose of this study, first is to find whether arthroscopic rotator cuff repair is changing the appearance of supraspinatus muscle atrophy in each and every patient.
- Trial name
- NCT02628457
- Testing
- arthroscopic rotator cuff repair
- Where
- South Korea
- Volunteers
- 209 people
- Sponsor
- CM Chungmu Hospital
Hamstring Muscle Repair, Hamstring Rupture
Clinical and Functional Outcomes at Least 2 Years After Hamstring Muscle Repair
This study is to evaluate functional outcomes of a new, intraoperative lateral positioning of the anchors on the tuber ischiadicum, in comparison to regular anatomical anchoring direct on top of the tuber ischiadicumafter…
- Trial name
- HamRepair (NCT04867746)
- Testing
- data collection by health questionnaires, assessment of muscle strength, assessment of gait
- Where
- Switzerland
- Volunteers
- 13 people
- Sponsor
- University Hospital, Basel, Switzerland
Post-Infarction Heart Rupture, Post-Infarction Ventricular Septal Defect
Mechanical Complications of Acute Myocardial Infarction
Although the incidence of post-AMI mechanical complications has decreased in the last decades, mortality in patients who develop these complications after AMI still remains very high.
- Conditions
- Post-Infarction Heart Rupture, Post-Infarction Ventricular Septal Defect, Post-Infarction Mitral Papillary Muscle Rupture
- Trial name
- CAUTION (NCT03848429)
- Testing
- Surgery for mechanical complications of acute myocardial infarction
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Maastricht University Medical Center
Rupture of Anterior Cruciate Ligament
Evaluation of rGH Therapy to Prevent Muscle Atrophy in Patients With ACL Tears
Anterior cruciate ligament (ACL) tears are among the most frequent traumatic knee injuries that occur in physically active individuals.
- Trial name
- NCT02420353
- Testing
- Somatropin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Rotator Cuff Injury (RCI), Metabolic Syndrome (MetS)
Impact of Metabolic Syndrome on Rehabilitation Outcomes in Rotator Cuff Injury
This prospective comparative study aims to investigate the effect of Metabolic Syndrome (MetS) on the outcomes of a standardized rehabilitation program in patients with Rotator Cuff Injuries (RCI).
- Trial name
- RMY-METS (NCT06946472)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Elif Dilara Durmaz
Shoulder Impingement Syndrome, Adhesive Capsulitis
Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management (HSSM)
Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management (HSSM) is a limited lateral approach to the shoulder arthroscopically guided.
- Conditions
- Shoulder Impingement Syndrome, Adhesive Capsulitis, Rotator Cuff Tear, Hill-Sachs Lesion
- Trial name
- HLSSM (NCT05897866)
- Testing
- Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management
- Where
- Syria
- Volunteers
- 44 people
- Sponsor
- Issa, Abdulhamid Sayed, M.D.
ACL - Anterior Cruciate Ligament Rupture
Description of Return to Sport in Amateur Athletes Who Underwent Several Functional Tests (K-STARTS, Vertical Jumps and Soleus Muscle Strength) After Initial ACL Reconstruction
ACL injuries are incapacitating for both professional and amateur athletes, with long-term repercussions on performance and return to sport (RTS). Surgical reconstruction of the ACL is the main treatment option.
- Trial name
- K-STARTS + (NCT07249645)
- Testing
- Physical tests
- Volunteers
- 230 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Meniscal Tear
Effect of Rehabilitation Programs Based on Eccentric Exercise of Knee Extensor Muscles in Isotonic and Isokinetic Conditions After Partial Menisectomy
A randomized clinical trial involving 32 individuals submitted to partial menisectomy will be conducted. Participants will be randomized into: Group I, submitted to a muscular rehabilitation program based on eccentric isokinetic…
- Trial name
- NCT02961530
- Testing
- Isokinetic eccentric exercises, Isotonic eccentric exercises
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Ventricular Septal Defect, Papillary Muscle Rupture
Mechanical Complications of Acute Myocardial Infarction: a Multicenter Prospective Study
In 2019, the international study titled "CAUTION Study - 1" (MeChanical complicAtions of acUte myocardial infarcTion: an InternatiOnal multiceNter cohort study), a retrospective multicenter study, was launched and registered on…
- Conditions
- Ventricular Septal Defect, Papillary Muscle Rupture, Cardiac Rupture, Pseudoaneurysm
- Trial name
- CAUTION 2 (NCT06676345)
- Testing
- Surgical treatment, Percutaneous treatment
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- Maastricht University Medical Center
Rupture of Anterior Cruciate Ligament, Muscle Degeneration
Can Targeted Exercise Improve Knee Strength Following ACLR (RATE)
Anterior cruciate ligament reconstruction (ACLR) is high volume surgery, carried out in about 2800 patients annually in Denmark per year.
- Conditions
- Rupture of Anterior Cruciate Ligament, Muscle Degeneration, Gait, Unsteady
- Trial name
- RATE (NCT02939677)
- Testing
- Targeted exercise
- Where
- Denmark
- Volunteers
- 51 people
- Sponsor
- University of Southern Denmark
Muscle Injuries
Efficacy of Platelet Rich Plasma for Treatment of Muscle Rupture With Haematoma
This is a multicenter, simple blind, masking of outcomes assessors, parallel, randomised clinical trial in patient with muscle rupture and with hematoma production.
- Trial name
- PRP-RICE (NCT01440725)
- Testing
- Autologous Platelet-rich plasma (PRP), Evacuation of haematoma
- Where
- Spain
- Volunteers
- 71 people
- Sponsor
- Institut de Terapia Regenerativa Tissular
Arthroplasty Complications, Muscle Weakness
Achilles Tendon for the Treatment of Gluteus Medius Insufficiency
Residual limping after total hip arthroplasty is a serious complication that lacks effective treatment. The purpose of this study is to evaluate a surgical treatment for residual limping and compare its results with non-surgical…
- Conditions
- Arthroplasty Complications, Muscle Weakness, Muscle Atrophy, Muscle Tear
- Trial name
- HLS (NCT05206838)
- Testing
- Surgical reconstruction of gluteus medius with Achilles tendon allograft
- Where
- Sweden
- Volunteers
- 44 people
- Sponsor
- Sahlgrenska University Hospital
Rotator Cuff Tears, Surgery
The Effect of Humeral Head Depressor Muscle Co-Activation Training in Terms of Functional Outcomes
Recent systematic reviews, and meta-analyses concluded that rotator cuff and scapular strengthening exercises should be included in rehabilitation programs for patients with middle-size rotator cuff muscle tear.
- Trial name
- NCT04154592
- Testing
- Humeral Head Depressor Muscle Co-Activation Training- Experimental Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Hacettepe University
Rotator Cuff Tendonitis, Bicipital Tendonitis
Diclofenac Patch for Treatment of Mild to Moderate Tendonitis or Bursitis
The primary purpose of this study is to assess the effectiveness of once daily application of a diclofenac sodium patch to the skin near or over the painful area.
- Conditions
- Rotator Cuff Tendonitis, Bicipital Tendonitis, Subdeltoid Bursitis of the Shoulder, Subacromial Bursitis of the Shoulder
- Trial name
- NCT00640939
- Testing
- diclofenac sodium
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- Cerimon Pharmaceuticals
Rotator Cuff Tears
Effect of the Muscle Strength and Range of Motion Training for Post-platelet Rich Plasma Injection in People With Rotator Cuff Partial Tear
Background: Although it is known that Platelet-Rich Plasma injections have a remarkable pain relief effect for patients with partial tears of the rotator cuff in the shoulder joint, many patients still experience limited muscle…
- Trial name
- NCT06192459
- Testing
- Modality physical therapy, Combined therapy:
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Hospital, Ministry of Health and Welfare