Clinical trials: Muscle Synthesis
- Condition Muscle Synthesis
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Muscle Function
A Pilot Clinical Trial on the Efficacy of Two Carnitine-Based Products on Muscle Function in Healthy Older Adults
This study evaluates two L-Carnitine-based products on muscle function in healthy older adults (55 to 70 years old). These products are suspected to improve muscle function and possibly promote building of muscle mass.
- Trial name
- 15CAHL (NCT02317536)
- Testing
- Carnipure Product 1, Carnipure Product 2
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Muscle Anabolism
Biomarkers of Muscle Anabolism (MK-0000-082)
This study will evaluate the ability of comparative proteomics to identify early biomarkers of muscle anabolism.
- Trial name
- NCT00812396
- Testing
- Comparator: low dose testosterone, Comparator: high dose testosterone
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Overweight
Daily Protein Intake Distribution and MPS (ARCIII)
To determine whether a balanced total daily dietary protein distribution supplemented with whey protein during a weight-loss intervention will result in increased muscle protein synthesis
- Trial name
- NCT02315014
- Testing
- whey protein
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy Elderly Muscle, Anabolically Resistant Elderly Muscle
Protein Nutrition for Muscle Hypertrophy in Older Adults
The primary objective is to determine the effect of reduced activity on the stimulation of myofibrillar FSR with protein feeding in the elderly.
- Trial name
- NCT02315391
- Testing
- isolated whey protein, micellar whey protein, glycine
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Muscle Synthesis
Effects of Protein Blends on Muscle Protein Synthesis in Healthy Older Adults
During aging there is a tendency for muscle protein synthesis (growth) to become less efficient and the resulting consequence leads to reduced muscle mass (sarcopenia) which can affect strength and mobility.
- Trial name
- NCT01847261
- Testing
- Soy Dairy Protein Blend, Positive Control (Dairy Whey Protein)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- DuPont Nutrition and Health
Muscle Synthesis
Protein Blends (Soy, Whey and Casein) for Muscle Synthesis
Soy protein is a high quality, plant-based protein that is comparable to milk, meat and eggs. Soy protein has a digestion rate (intermediate) compared to whey (fast) and casein (slow).
- Trial name
- NCT01358305
- Testing
- Protein Blend
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- DuPont Nutrition and Health
Protein Synthesis Overnight
Protein Intake on Muscle Protein Synthesis Overnight
This trial is an exploratory study in order to determine whether the ingestion of one type of protein (milk protein/CHO/Fat) vs.placebo (CHO/Fat) 2 hours before bed time results in the extension of the post-prandial window of…
- Trial name
- NCT02041143
- Testing
- Milk protein
- Where
- Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy
GLPG0492 Pharmacodynamics
GLPG0492 is a selective androgen receptor modulator: the compound should help protect against (or help restore) muscle loss in case of immobilization (e.g.
- Trial name
- NCT01538420
- Testing
- GLPG0492
- Where
- Belgium
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Lakefront Biotherapeutics NV
Muscle Protein Synthesis
Effect of Protein-nutrition Beverages on Muscle Protein Synthesis in Women
This study investigates whether a protein-nutrition beverage can increase muscle protein synthesis to a similar magnitude as a control beverage.
- Trial name
- NCT02282566
- Testing
- Protein-nutrition beverage
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Muscle Anabolism
A Study to Evaluate the Effect of Testosterone on Muscle Fractional Synthetic Rate (MK-0000-064)
This is a study to evaluate the use of fractional synthetic rate as an early biomarker of muscle anabolism (muscle build-up).
- Trial name
- NCT00816712
- Testing
- Comparator: Testosterone 300 mg, intramuscular injection, Comparator: Testosterone 100 mg, Intramuscular injection
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Nutrition
Impact of Protein Formulations on the Stimulation of Muscle Protein Synthesis
The overall objective of this study is to determine the effects of ingesting protein that slowly releases amino acids into the blood vs.
- Trial name
- NCT07501403
- Testing
- Control Protein then Extended Release Nutritional Protein, Extended Release Protein then Control Nutritional Protein
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- VitaKey Inc.
Ventral Incisional Hernia
Open Complex Ventral Incisional Hernia Repair Using Biosynthetic Material for Midline Fascial Closure Reinforcement
Prospective, multicenter, observational study to evaluate performance of GORE® BIO-A® Tissue Reinforcement when used to reinforce midline fascial closure in single-staged open complex ventral incisional hernia repair.
- Trial name
- COBRA (NCT01325792)
- Testing
- GORE® BIO-A® Tissue Reinforcement
- Where
- 9 sites in United States, Netherlands
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- W.L.Gore & Associates
Tendon Injuries
A Methodology Study to Assess Muscle Damage After Eccentric Exercise
An isolated bout of unaccustomed maximal eccentric exercise is associated with muscle force loss for 2-4 days, mild reversible muscle tenderness, and ultra-structural damage to the muscle fibers, elevation of muscle proteins in…
- Trial name
- NCT02014662
- Testing
- Eccentric exercise
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline