Clinical trials: Muscle Tumor
Radical Cystectomy, Muscle-Invasive Bladder Carcinoma
Clinical Utility of VI-RADS in Diagnosis of MIBC
Bladder Cancer (BCa) is the 9th most common cancer worldwide. In general, BCa is presented as a non-muscle invasive bladder cancer (NMIBC) in 70% of patients and treated with transurethral resection of bladder tumor (TUR-BT).
- Conditions
- Radical Cystectomy, Muscle-Invasive Bladder Carcinoma, Multiparametric MRI, Vesical Imaging Report and Data System
- Trial name
- NCT05097404
- Where
- South Korea
- Volunteers
- 73 people
- Sponsor
- Samsung Medical Center
Uterine Fibroid
Microwave Ablation for Uterine Fibroids
This study is aimed to evaluate the clinical safety and effectiveness of Microwave ablation (MWA) in treating patients with uterine fibroid.
- Trial name
- NCT04073485
- Testing
- Microwave ablation
- Where
- Hong Kong
- Volunteers
- 6 people
- Sponsor
- Chinese University of Hong Kong
Non-Muscle Invasive Bladder Cancer
Mood Alterations in the Patients With Non-Muscle Invasive Bladder Cancer Treated With BCG
The purpose of this study is to evaluate mood changes in patients with Non-Muscle Invasive Bladder Cancer who are receiving intravesical Bacillus Calmete-Guerin (BCG).
- Trial name
- NCT05672615
- Testing
- Questionnaires, Daily Mood Diaries, Urine Specimen Collection
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Johns Hopkins University
Central Nervous System Embryonal Tumor With Rhabdoid Features, Central Nervous System Embryonal Tumor, Not Otherwise Specified
Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors
This phase I/II trial studies the side effects and best dose of adavosertib and irinotecan hydrochloride in treating younger patients with solid tumors that have come back (relapsed) or that have not responded to standard therapy…
- Conditions
- Central Nervous System Embryonal Tumor With Rhabdoid Features, Central Nervous System Embryonal Tumor, Not Otherwise Specified, Central Nervous System Ganglioneuroblastoma, Embryonal Tumor With Multilayered Rosettes, C19MC-Altered
- Trial name
- NCT02095132
- Testing
- Adavosertib, Irinotecan Hydrochloride
- Where
- 24 sites in United States, Canada
- Volunteers
- 76 people
- Sponsor
- National Cancer Institute (NCI)
Bladder Cancer
Efficacy and Safety Study of Apaziquone vs. Placebo in Patients With Non-Muscle Invasive Bladder Cancer (NMIBC)
This is an international, multicenter, double-blind, placebo-controlled, randomized study. All eligible patients entering the open label phase of the study will receive a single immediate instillation of apaziquone (4 mg in 40 mL…
- Trial name
- NCT01469221
- Testing
- Apaziquone
- Where
- 29 sites in United States, Czechia and 2 more
- Volunteers
- 47 people
- Sponsor
- Spectrum Pharmaceuticals, Inc
Cancer of the Head and Neck
Effects of Expiratory Muscle Strength Training on Airway Protection and Swallowing in Chronic Dysphagia After Radiation Therapy
Radiation therapy for head and neck cancer (HNC) is associated with the development of swallowing difficulties, or dysphagia. Dysphagia has profound negative effects on the health, nutritional status, and quality of life of HNC…
- Trial name
- NCT03620084
- Testing
- Expiratory Muscle Strength Training (EMST)
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Singapore General Hospital
Myasthenia Gravis
The Effect of Spinal Stabilization Exercises in Patients With Myasthenia Gravis
Myasthenia Gravis (MG) is an autoimmune disease characterized by increased exercise-induced fatigue and muscle weakness. MG is a disease caused by impaired receptor function due to antibodies to nicotinic acetylcholine receptors…
- Trial name
- NCT03743740
- Testing
- Spinal stabilization exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Hacettepe University
Metrorrhagia, Pelvic Pain
Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL)
In this project, the proposition is that the use of daily dosed Myfembree ( a combination of relugolix with estradiol and norethindrone acetate), FDA-approved medication to treat heavy menses fibroid-related symptoms, has the…
- Conditions
- Metrorrhagia, Pelvic Pain, Menorrhagia, Leiomyoma
- Trial name
- SOUL (NCT05538689)
- Testing
- Myfembree Oral Product
- Where
- 6 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
NMIBC, MIBC
A Multicenter Prospective Cohort Study on Monitoring Recurrence of Urothelial Carcinoma Based on Detection of Urinary Microscopic Residual Disease (MRD)
This was a multicenter, prospective, non-interventional, observational cohort study, and the enrolled patients were divided into four cohorts: cohort I was patients with high-risk upper tract urothelial carcinoma (UTUC) (pT3-4 or…
- Conditions
- NMIBC, MIBC, UTUC
- Trial name
- NCT06991868
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University First Hospital
Genitourinary Syndrome of Menopause (GSM), Breast Cancer
Efficacy of Non-ablative Radiofrequency Combined With Pelvic Floor Muscle Training for Genitourinary Syndrome of Menopause in Breast Cancer Survivors (RF-SGM)
The goal of this clinical trial is to find out whether non-ablative radiofrequency (RF) applied together with pelvic-floor muscle exercises can ease vaginal dryness and other symptoms of genitourinary syndrome of menopause (GSM)…
- Trial name
- NCT07034976
- Testing
- Active Radiofrequency (Capenergy C500 UpGradeC200)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Endometrial Cancer, Cardiovascular Diseases
Strive Cardio for Endometrial Cancer Survivors
STRIVE Cardio is a 12-week exercise intervention study with the goal to improve functional fitness and cardiovascular health for women who have completed treatment for non-metastatic endometrial cancer within the last five years…
- Trial name
- NCT06534008
- Testing
- 12-week home-based exercise intervention
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Jess S. Gorzelitz
Inclusion Body Myositis, Myotonic Dystrophy 1
The Use of Assistive Gait Devices Can Reduce the Risk of Falls in Patients With Neuromuscular Diseases Following a Training Period.
The planned project is an intervention study to assess the risk of falling after adaptation of an assistive gait devices in patients with the following neuromuscular diseases: Inclusion body myositis, myotonic dystrophy, limb…
- Conditions
- Inclusion Body Myositis, Myotonic Dystrophy 1, Myotonic Dystrophy 2, Facio-Scapulo-Humeral Dystrophy
- Trial name
- Risk of fall (NCT07072676)
- Testing
- Assistive gait devices combined with physiotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- LMU Klinikum
Cancer Survivors, Obesity
Inspiratory Muscle Training in Obese Breast Cancer Survivors
The investigators propose a randomized controlled trial to determine the effectiveness of inspiratory muscle training in improving exercise tolerance among stage 0-III obese breast cancer survivors.
- Conditions
- Cancer Survivors, Obesity, Breast Cancer
- Trial name
- IMOCS (NCT05193149)
- Testing
- Inspiratory muscle training, Exercise training
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Colorectal Cancer
Core Stability Program in Colorectal Cancer Survivors
The purpose of this study is to determine the effects of physical training program to improve deep stabilizer muscle in colorectal cancer survivors
- Trial name
- NCT02052050
- Testing
- core stability
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Granada
Uterine Fibroids
Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 3)
The primary objective of this study was to show superiority in the treatment of HMB of vilaprisan in subjects with uterine fibroids compared to placebo.
- Trial name
- NCT03400943
- Testing
- Vilaprisan (BAY1002670)
- Where
- 103 sites in United States, Bulgaria and 7 more
- Volunteers
- 93 people
- Sponsor
- Bayer
BRCA1 Mutation, High-grade Serous Ovarian Cancer
Breast Cancer BRCA1 Carriers: a Pilot Study
The purpose of this study is to examine how a single dose of MIFEPREX® (mifepristone) affects the breast tissue in patients with BRCA1 (a gene that normally acts to restrain the growth of cells in the breast, but if it mutates…
- Conditions
- BRCA1 Mutation, High-grade Serous Ovarian Cancer, TNBC - Triple-Negative Breast Cancer
- Trial name
- NCT05062174
- Testing
- Mifepristone 200 MG, Prophylactic mastectomy
- Where
- 2 sites in United States
- Sponsor
- Indiana University
Sarcopenia, Oncology
Effect of Sarcopenia on the Occurrence of Toxicity Related to Anti-cancer Treatments
The goal of this clinical trial is to learn about the effect of sarcopenic status on the occurrence of treatment-related toxicity during the first course of anti-cancer treatment in several types of cancers.
- Conditions
- Sarcopenia, Oncology, Physical Inactivity, Toxicity Due to Chemotherapy
- Trial name
- SARC-ONCO (NCT06274268)
- Testing
- Sarcopenia diagnostic test
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Centre Hospitalier Metropole Savoie
Endometriosis, Adenomyosis of Uterus
Artificial Intelligence Into Ultrasound Diagnostics in Reproductive Medicine
The goal of this observational study is to develop and validate artificial intelligence (AI)-based algorithms that support ultrasound diagnosis of endometriosis, adenomyosis, myometrial masses, uterine malformations, and impaired…
- Conditions
- Endometriosis, Adenomyosis of Uterus, Leiomyoma (Uterine Fibroids), Uterine Neoplasms
- Trial name
- AUDRIE (NCT07810920)
- Where
- Hungary
- Volunteers
- 1,600 people
- Sponsor
- Semmelweis University
Leiomyoma
A Study to Evaluate the Safety and Effectiveness of Asoprisnil in the Treatment of Uterine Fibroids
This study was designed to determine the safety and effectiveness of 3 asoprisnil doses compared to placebo, taken for 12 weeks by women with uterine fibroids.
- Trial name
- NCT00160459
- Testing
- Asoprisnil
- Volunteers
- 129 people
- Sponsor
- Abbott
Myoma, Uterine Bleeding, Dysfunctional
Observation of Long-term Effects on Endometrium and Uterine Fibroids in Women With Ulipristal Acetate Therapy
A prospective observational study on italian women undergoing ulipristal acetate (uPa) therapy for symptomatic myomas and its impact on symptomatology and moreover on myomas architecture.
- Conditions
- Myoma, Uterine Bleeding, Dysfunctional, Uterine Bleeding Heavy, Dysmenorrhea
- Trial name
- NCT03972917
- Testing
- Transvaginal ultrasonographic examination
- Where
- Italy
- Volunteers
- 89 people
- Sponsor
- University of Campania Luigi Vanvitelli
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.