Clinical trials: Muscle Tumor
Non-muscle Invasive Bladder Cancer (NMIBC)
Evaluating the Safety and Performance of the Eight Medical Hyperthermia System IV 1.0 for HIVEC in NMIBC.
The goal of this clinical trial is to evaluate the safety and performance of the Eight Medical Hyperthermia System IV 1.0 when used to deliver recirculating hyperthermic intravesical chemotherapy (HIVEC) with mitomycin C (MMC) in…
- Trial name
- NCT07758881
- Testing
- Hyperthermic intravesical chemotherapy (HIVEC)
- Where
- 2 sites in Belgium
- Volunteers
- 30 people
- Sponsor
- Eight Medical International BV
HCC - Hepatocellular Carcinoma
Sarcopenia and Systemic Therapy in HCC
This is a multi-center, retrospective observational study in patients with liver cancer (HCC) to assess the impact of sarcopenia (muscle loss) on the prognosis, duration, and tolerance of systemic treatment.
- Trial name
- Sarco HCC (NCT06805552)
- Where
- Italy
- Volunteers
- 270 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Non-Muscle Invasive Bladder Cancer (NMIBC)
Study of APL-1202 in Non-Muscle Invasive Bladder Cancer Patients Who Are Resistant to One Induction Course of BCG Treatment
A Phase Ib, open label, non randomized study to measure the safety and PK characteristics of APL-1202 at steady-state in adult male and female BCG resistant NMIBC patients when it is administered alone and concurrently with BCG.
- Trial name
- NMIBC (NCT03672240)
- Testing
- APL-1202
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Asieris Pharmaceutical Technologies Co., Ltd.
Stem Cell Transplantation
Adherence, Viability, Clinical Evolution and Therapeutic Efficacy in Patients Undergoing Bone Marrow Transplantation
Hematological neoplasms originate from the differentiation and proliferation of abnormal lymphatic or myeloid cells that alter the constitution of elements of the blood, bone marrow and lymph nodes.
- Trial name
- NCT06134297
- Testing
- Cycle ergometer, Strength Training - elastic band and shin guards, Cycle ergometer, elastic band and shin guards
- Where
- Brazil
- Volunteers
- 93 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Giant Cell Tumors
Tenosynovial Giant Cell Tumors (TGCT) Observational Platform Project
TGCT is a rare disease that is difficult to manage, surgical resection is the primary treatment currently available. To date no disease registry exists and there is little data available detailing the management of patients with…
- Trial name
- TOP (NCT02948088)
- Where
- 15 sites in United States, Austria and 6 more
- Volunteers
- 183 people
- Sponsor
- Daiichi Sankyo
Head and Neck Neoplasms
DAHANCA 25A: Resistance Training and Dietary Supplements as Intervention for Regaining Muscle Mass Following Radiotherapy in Head and Neck Cancer Patients
The purpose of this study is to investigate whether resistance training in combination with dietary supplementation is tolerable among head and neck cancer patients and to evaluate the possible effect on muscle mass, strength and…
- Trial name
- NCT01025518
- Testing
- Resistance training, Protein and creatine
- Where
- 2 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- Danish Head and Neck Cancer Group
Adult Angiosarcoma, Adult Desmoplastic Small Round Cell Tumor
Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma
This phase I trial is studying the side effects and best dose of cixutumumab given together with doxorubicin hydrochloride and to see how well they work in treating patients with unresectable, locally advanced, or metastatic soft…
- Conditions
- Adult Angiosarcoma, Adult Desmoplastic Small Round Cell Tumor, Adult Epithelioid Sarcoma, Adult Extraskeletal Myxoid Chondrosarcoma
- Trial name
- NCT00720174
- Testing
- Cixutumumab, Doxorubicin Hydrochloride, Laboratory Biomarker Analysis
- Where
- 13 sites in United States
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
Bladder Cancer
High-power Green-light Laser Endoscopic Submucosal Dissection for Non-muscle-invasive Bladder Cancer
A retrospective study was designed in this study. The surgeon performed high-power green-light laser endoscopic submucosal dissection (HPL-ESD) for the treatment of primary non-muscle-invasive bladder cancer (NMIBC).
- Trial name
- NCT05290623
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Shandong Provincial Hospital
Breast Cancer Female
Biofeedback Training on Shoulder Muscles Strength Post Mastectomy
PURPOSE:The purpose of the study is to evaluate the effect of biofeedback on shoulder muscles strength post mastectomy. BACKGROUND: The most common complications following mastectomy are pain, ipsilateral lymphedema of the upper…
- Trial name
- NCT06226688
- Testing
- Biofeedback device and other group control group, Control group
- Where
- 2 sites in Egypt
- Volunteers
- 54 people
- Sponsor
- Cairo University
Neuroblastoma, Rhabdomyosarcoma
A Vaccine Study for High Risk Cancers
The purpose of this study is to determine the safety and immunological effects of a vaccine for people diagnosed with high risk neuroblastoma, osteogenic sarcoma, and rhabdomyosarcoma.
- Conditions
- Neuroblastoma, Rhabdomyosarcoma, Osteogenic Sarcoma
- Trial name
- NCT00944580
- Testing
- MAGE-A1, MAGE-A3, and NY-ESO-1 Vaccine
- Sponsor
- Penn State University
Breast Cancer, Shoulder Dysfunction
Effectiveness of a Visual Biofeedback Program Versus Conventional Physiotherapy on Shoulder Mobility, Strength, and Function in Women After Breast Cancer Surgery
This study aims to evaluate the effectiveness of a physiotherapy program incorporating visual biofeedback compared to a conventional physiotherapy program in improving shoulder function in women following breast cancer surgery.
- Trial name
- NCT07542106
- Testing
- Experimental Group: Physiotherapy + Visual Biofeedback
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Cancer
Nab-paclitaxel in Combination with Gemcitabine for Pediatric Relapsed and Refractory Solid Tumors
This is a research study for people who have a solid tumor that was not effectively treated by conventional therapy or for which there is no known effective therapy.
- Trial name
- NCT03507491
- Testing
- Gemcitabine, Nab-paclitaxel
- Where
- 4 sites in United States
- Volunteers
- 24 people
- Sponsor
- Emory University
Colorectal Cancer
EDICT - Exercise inDuced Changes In Colorectal Cancer Tissues
This pilot study looks to explore the biological effects of exercise on cancer and muscle cells using a two week exercise program (HIThigh intensity training) on 20 patients with newly diagnosed and operable colorectal cancer…
- Trial name
- EDICT (NCT02056691)
- Testing
- Exercise programme, Muscle biopsy
- Where
- 2 sites in United Kingdom
- Volunteers
- 16 people
- Sponsor
- The Royal Bournemouth Hospital
Fibroid Uterus, Polyp Uterus
Comparison of Operative Hysteroscopy Performed in the Operating Room Versus Outpatient Settings
This is an observational prospective monocentric study which aims to compare operative hysteroscopies performed in the operating room under general or loco-regional anesthesia and those performed outside the operating room…
- Conditions
- Fibroid Uterus, Polyp Uterus, Retained Products of Conception
- Trial name
- NCT07146659
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Bladder Cancer
Mitomycin C Versus Bacillus Calmette-Guerin in the Intravesical Treatment of Non-Muscle-Invasive Bladder Cancer Patients
The purpose of this study is to compare the bladder cancer treatments, Mitomycin C (MMC) and Bacillus Calmette Guerin (BCG), to find out which is better.
- Trial name
- NCT00974818
- Testing
- Mitomycin C (MMC), Bacillus Calmette-Guerin (BCG)
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Bladder Cancer
Optimal Adjuvant Intravesical Therapy for Intermediate Risk Non Muscle Invasive Bladder Cancer: A Randomized Controlled Trial
The objective of this prospective, single-center randomized controlled trial is to identify the optimal adjuvant intravesical therapy in patients with intermediate risk (IR) non muscle invasive bladder cancer by comparing two…
- Trial name
- NCT05146635
- Testing
- Intravesical Bcg, Intravesical chemotherapy (epirubicin)
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Uterine Fibroid
The Efficacy and Safety of Preoperative Misoprostol in Blood-loss Reduction During Myomectomy.
Open myomectomy remains the principal treatment for symptomatic fibroids in sub-Saharan countries irrespective of fertility desires.
- Trial name
- MM (NCT03509168)
- Testing
- Misoprostol Pfizer Brand, Non-insertion of Misoprostol Pfizer Brand
- Where
- Uganda
- Volunteers
- 46 people
- Sponsor
- Makerere University
Cancer, Palliative Care
Therapeutic Touch in Cancer Patients Receiving Palliative Care
This study aims to examine the effect of therapeutic touch applied to advanced cancer patients receiving palliative care on sleep quality and fatigue severity.
- Conditions
- Cancer, Palliative Care, Therapeutic Touch, Sleep
- Trial name
- NCT07524179
- Testing
- Therapeutic Touch, Routine Palliative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Erzurum Technical University
Rhabdomyosarcoma
Clinico-biological Study/Characterization of Rhabdomyosarcoma in Adolescents and Young Adults, 15-25-year-old Patients
Rhabdomyosarcoma (RMS) stands for the most frequent soft tissue sarcoma in children and, adolescents and young adults (AYA, 15-25-year-old population), accounting for approximately half of the whole soft tissue sarcomas in these…
- Trial name
- RMS-AJA-1701 (NCT03462888)
- Where
- 20 sites in France
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Centre Oscar Lambret
Bladder Cancer, Urinary Bladder Neoplasms
A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)
Researchers are looking for new ways to treat high-risk non-muscle invasive bladder cancer (HR NMIBC). NMIBC is cancer in the tissue that lines the inside of the bladder and has not spread to the bladder muscle or outside of the…
- Trial name
- NCT07222488
- Testing
- MK-3120
- Where
- 17 sites in United States, Austria and 10 more
- Volunteers
- 45 people
- Sponsor
- Merck Sharp & Dohme LLC
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