Clinical trials: Muscle Tumor
Muscle-Invasive Bladder Carcinoma, Programmed Cell Death Protein 1 Inhibitor
Treating Muscle-invasive Bladder Cancer With A Non-surgical Method Consisting of Anti-PD-1 Therapy and Chemoradiation
The goal of this Phase 2 trial is to evaluate a non-surgical bladder-preserving treatment mode which consists of neoadjuvant chemotherapy plus anti-programmed cell death protein 1 (anti-PD-1) therapy followed by radiotherapy plus…
- Conditions
- Muscle-Invasive Bladder Carcinoma, Programmed Cell Death Protein 1 Inhibitor, Radiotherapy
- Trial name
- BCIRT-01 (NCT05975307)
- Testing
- Toripalimab, Gemcitabine, Cisplatin
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Sun Yat-sen University
Non Muscle Invasive Bladder Cancer
Prospective Randomized Comparison of Transurethral Resection by Mean of White Light and Narrow Band Imaging
To date, fluorescence and narrow band imaging cystoscopy have been tested in many prospective within patient trials but only as an "add on" procedure.
- Trial name
- NCT01004211
- Testing
- Narrow band imaging transurethral resection, Standard transurethral resection
- Where
- 2 sites in Italy
- Volunteers
- 188 people
- Sponsor
- Paolo Puppo
Leiomyoma, Uterine
Clinical Research on the Application of Single-channel Uterine Fibroid Morcellation System in Laparoscopic Myomectomy
Research Purpose The purpose of this study is to explore whether the application of a single-channel uterine fibroid morcellation system compared to a multi-channel specimen retrieval bag during laparoscopic myomectomy can…
- Trial name
- NCT06442605
- Testing
- single-channel uterine fibroid morcellation system, Multi-channel specimen retrieval bag + conventional laparoscopic uterine fibroid morcellator
- Where
- China
- Volunteers
- 22 people
- Sponsor
- First People's Hospital of Hangzhou
Non-muscular Invasive Bladder Cancer
BCG for Therapeutic Use Phase I Clinical Trial
This clinical study adopted a single-arm, open, single-centertrial design. The purpose of this study was to evaluate the safety and tolerability, PK characteristics, shedding and immune response characteristics of BCG for…
- Trial name
- NCT06100653
- Testing
- BCG for therapeutic use
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Liver Cancer, Sarcopenia
Relationship Between Liver Cancer and Sarcopenia
By tracking the short-term and long-term results of patients after hepatectomy, the difference of short-term results between patients with sarcopenia and patients without sarcopenia was analyzed, and the correlation between…
- Trial name
- NCT05339919
- Testing
- gait speed; ct scan;grip strength and chair stand test
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Fatigue Syndrome, Chronic, Epstein-Barr Virus Infection
Mental Training for CFS Following EBV Infection in Adolescents
The general aim of this study is to investigate the effect of an individually tailored mental training program in adolescents developing chronic fatigue syndrome (CFS) after an acute Epstein Barr-virus (EBV) infection.
- Trial name
- NCT02499302
- Testing
- Mental training
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital, Akershus
Leiomyoma, Laparoscopic Myomectomy
Temporary Clipping of the Uterine Arteries During Laparoscopic Myomectomy
The aim is to verify, whether intraoperative temporary clipping of the uterine vessels with vascular clips can reduce blood loss significantly.
- Trial name
- NCT01530802
- Testing
- clipping of uterine arteries during laparoscopic myomectomy
- Where
- 2 sites in Germany
- Volunteers
- 166 people
- Sponsor
- Charite University, Berlin, Germany
Muscle-Invasive Bladder Carcinoma, Bladder Cancer
Bladder Preservation or Cystectomy for MIBC
In this research study, investigators will assess whether it is feasible to use information from the genes of a tumor combined with evaluation of the tumor response to systemic therapy to determine if bladder sparing…
- Conditions
- Muscle-Invasive Bladder Carcinoma, Bladder Cancer, Urothelial Carcinoma
- Trial name
- NCT07821177
- Testing
- Gemzar, Cisplatin, Adrucil
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Dana-Farber Cancer Institute
Cancer, Cachexia
Mitochondrial Respiratory Function in Mammalian Skeletal Muscle
The purpose of this study is to determine whether skeletal muscle mitochondrial function is altered in patients with head and neck cancer compared to healthy controls.
- Trial name
- NCT02650570
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Menorrhagia, Dysfunctional Uterine Bleeding
Study of Conventional Laparoscopic Hysterectomy Versus Robot-Assisted Laparoscopic Hysterectomy at a Teaching Institution
Approximately 600,000 women undergo hysterectomy each year in the United States, of which 12% are laparoscopic. The most common indications for hysterectomy are: symptomatic uterine leiomyomas (40.7%), endometriosis (17.7%), and…
- Conditions
- Menorrhagia, Dysfunctional Uterine Bleeding, Leiomyoma, Pelvic Pain
- Trial name
- NCT01581905
- Testing
- Conventional Laparoscopic Hysterectomy (LH), Robot Assisted Hysterectomy
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Dupuytren Contracture, Disease Progression
Natural Disease Progress of Dupuytren Disease
Dupuytren disease (DD) is a progressive fibromatosis of the palmar fascias of the hand and fingers, which may lead to extension deficits of the fingers.
- Trial name
- DD (NCT01923103)
- Where
- Netherlands
- Volunteers
- 261 people
- Sponsor
- University Medical Center Groningen
Bladder Cancer, Liquid Biopsy
Guiding Value of Urinary Tumor DNA Testing in Repeat Transurethral Resection of Non-Muscle-Invasive Bladder Cancer
Non-muscle-invasive bladder cancer (NMIBC) accounts for approximately 75% of newly diagnosed bladder cancers and is characterized by a high risk of recurrence and progression.
- Conditions
- Bladder Cancer, Liquid Biopsy, Repeat Transurethral Resection of Bladder Tumor
- Trial name
- NCT07187635
- Testing
- Second Transurethral Resection of Bladder Tumor (re-TURBT), utDNA Testing (Urine Tumor DNA Detection)
- Where
- 7 sites in China
- Volunteers
- 196 people
- Sponsor
- Tianjin Medical University Second Hospital
Metastatic Invasive Breast Cancer, Metastatic Invasive Gynecologic Cancer
Promoting Active Living Among People With Advanced Cancer
Individuals with metastatic cancer are living longer but often face persistent fatigue, functional decline, and psychological distress. Physical activity is generally safe for this population and may alleviate symptom burden.
- Trial name
- NCT07238023
- Testing
- Acceptance- and mindfulness-based physical activity promotion
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Oklahoma
Temporomandibular Joint Disorders
Laser Therapy on TMJ Disorders After Head and Neck Cancer.
Temporomandibular disorder (TMD) is a term describing musculoskeletal conditions of the face, jaw and temporal regions. TMD is frequently associated with pain and/or dysfunction such as impaired jaw function, pain in the…
- Trial name
- NCT05868460
- Testing
- High intensity laser, traditional physical therapy exercise program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Muscle Invasive Bladder Cancer, High Risk Urothelial Carcinoma of the Upper Urinary Tracts
Dose Dense MVAC for Muscle Invasive Bladder Cancer
Standard treatment for early stage bladder cancer is chemotherapy with methotrexate (M), vinblastine (V), adriamycin (A), and cisplatin (C) followed by surgical removal of any remaining cancer and the bladder with the intent of…
- Trial name
- NCT01031420
- Testing
- single arm dose dense MVAC
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- Fox Chase Cancer Center
Handgrip Strength Test, Sarcopenia
Feasibility of Systematic Handgrip Strength (HGS) Testing and Short-term Changes in Muscle Strength in Digestive Cancer Patients Treated by Chemotherapy
Sarcopenia is defined as a loss in skeletal muscle mass and function (strength and/or performance). There is a high prevalence in elderly and in patients with cancer.
- Conditions
- Handgrip Strength Test, Sarcopenia, Digestive Cancer, Muscle Strength
- Trial name
- FIGHTDIGO (NCT02797197)
- Testing
- handgrip strength test, chemotherapy
- Volunteers
- 201 people
- Sponsor
- CHU de Reims
Prostate Cancer, Metastatic Prostate Cancer
The Effect of a Structured Strength and Endurance Training Program on Quality of Life, Fitness, Blood Parameters and Survival in Prostate Cancer Patients
Prostate cancer is the second most common cancer among men. Many patients experience a significantly reduced quality of life due to either the cancer itself or the side effects of treatment.
- Conditions
- Prostate Cancer, Metastatic Prostate Cancer, Prostate Cancer (Post Prostatectomy), Prostate Cancer Patients Treated by Radiotherapy
- Trial name
- ZMoveMent-1 (NCT07126860)
- Testing
- Structured combined resistance and aerobic training, Standard of Care
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Fibroids
Barbed Suture Versus Traditional Suture Material for Laparoscopic Myomectomy
The objective of this study is to determine if the use of a new type of barbed suture material for laparoscopic myomectomy (surgical removal of fibroids) versus the traditional approach of suturing with conventional suture…
- Trial name
- NCT01347385
- Testing
- Laparoscopic myomectomy with unidirectional barbed suture, Traditional suture material
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Sunnybrook Health Sciences Centre
Arthralgia, Musculoskeletal Complications
Vitamin D Deficiency, Muscle Pain, Joint Pain, and Joint Stiffness in Postmenopausal Women Receiving Letrozole For Stage I-III Breast Cancer
This phase II trial is studying vitamin D deficiency, muscle pain, joint pain, and joint stiffness in postmenopausal women receiving letrozole for stage I-III breast cancer.
- Conditions
- Arthralgia, Musculoskeletal Complications, Pain, Recurrent Breast Cancer
- Trial name
- NCT00416715
- Testing
- letrozole, calcium carbonate, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Breast Cancer, Upper Extremity
Combined Upper Extremity Resistance and Aerobic Exercise Training in Patients With Breast Cancer
According to updated data from the International Agency for Research on Cancer (IARC) for 2022, breast cancer in women is responsible for one in four cancer cases and one in six cancer deaths worldwide and is the second leading…
- Conditions
- Breast Cancer, Upper Extremity, Resistance Exercise, Aerobic Exercise
- Trial name
- NCT07070791
- Testing
- Upper Extremity Aerobic Exercise Training, Upper Extremity Progressive Resistance Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
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