Clinical trials: Muscle Weakness | Patient
Paraparesis, Tetraparesis
Prospective Cohort Follow-up of French Patients With Profound and Multiple Disabilities: Healthcare Pathways and Quality of Life Among Patients and Their Families
The studies conducted so far concerning the medical and paramedical cares provided to patients with profound and multiple disabilities (PMD) often show important limitations: samples are too small or very heterogeneous, generally…
- Conditions
- Paraparesis, Tetraparesis, Hemiparesis, Ataxia
- Trial name
- Eval-PLH (NCT02400528)
- Testing
- quality of life questionnaires
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Gait Impairment, Cerebral Palsy (CP)
Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical Setting
The primary objective of the study is to validate the safety and clinical performance of the ABLE Kids device in pediatric patients with neurological gait disorders or muscular weakness during a 10-session gait training program…
- Conditions
- Gait Impairment, Cerebral Palsy (CP), Neuromuscular Diseases (NMD), Spinal Cord Injuries (SCI)
- Trial name
- NCT07745712
- Testing
- ABLE Kids
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- ABLE Human Motion S.L.
Weakness
Effect of All-Stim 2 Quadriceps Treatments on Limb Muscle Strength In Mechanically Ventilated Patients
Patients that are on mechanical ventilators in medical intensive care units (MICU) have extremely weak leg muscles. Currently there is no treatment to prevent or reverse this weakness.
- Trial name
- NCT02332187
- Testing
- Active electrical stimulation using an All Stim stimulator
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Gerald Supinski
Acute Pain, Atrophic
Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy
The purpose of this study is to examine deficits in activation and motor patterns, as well as central drive in patients with rotator cuff tendinopathy.
- Conditions
- Acute Pain, Atrophic, Goals, Impairment
- Trial name
- NCT02971072
- Testing
- Subacromial injection, Physical Therapy
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Postprocedural Delayed Gastric Emptying
The Effect of Oxytocin on the Gastric Emptying
The investigators are going to examine whether oxytocin has a prokinetic effect on gastric emptying in patients suffering from gastro paresis. Oxytocin infusion will be compared with sodium chloride infusion.
- Trial name
- NCT00776360
- Testing
- oxytocin
- Volunteers
- 12 people
- Sponsor
- Skane University Hospital
Mechanically Ventilated Patients
Early Directed Physical Therapy in the Management of Mechanically Ventilated Patients in a Medical Intensive Care Unit
To study all ICU patients with an independent baseline functional status, who experience a critical illness requiring intubation and mechanical ventilation, evaluating the role of protocol-directed, early physical and…
- Trial name
- NCT00322010
- Testing
- early PT OT
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Chicago
Muscle Weakness
Respiratory Muscle Training in Subacute Stroke Patients
This study is divided for development in two complementary work packages justified by the need to incorporate new strategies to optimize rehabilitation outcomes in stroke patients.
- Trial name
- RETORNUS (NCT02125760)
- Testing
- Inspiratory Muscle Training (IMT), High-intensity IMT
- Where
- Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Covid19, Diaphragm Injury
Respiratory Muscle Assesment in COVID-patients Without Hospitalization
Fatigue and exercise intolerance after survived COVID-19-infection might be related to weakness of the respiratory muscles. The aim of the project is to measure respiratory muscle function and strength in our respiratory…
- Trial name
- RMA-COVID-19 (NCT06105450)
- Testing
- Comprehensive assessment of respiratory muscle function.
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- RWTH Aachen University
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
The Effect of PEMF for Patients With Quadriceps Muscle Weakness After ACLR
In Hong Kong, over 3000 Anterior Cruciate Ligament Reconstructions (ACLR) are performed each year in order to restore knee function after an ACL injury. The ultimate goal of ACLR is to fulfil the return-to-play (RTP) criteria.
- Trial name
- NCT05184023
- Testing
- Pulse Electromagnetic Field
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Cancer, Cancer Cachexia
Effects of WB-EMS and Specific Dietary Supplements on Cancer Patients
Patients suffering from cancer often experience a loss of muscle mass and strength during disease and its therapy. Muscle wasting is the main characteristic of the so-called cancer cachexia syndrome and responsible for many…
- Conditions
- Cancer, Cancer Cachexia, Weight Loss, Muscle Loss
- Trial name
- NCT03151291
- Testing
- β-hydroxy-β-methylbutyrate (HMB), L-carnitine (LC), Eicosapentaenoic acid (EPA)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Sugammadex Reversal Time, Muscle Weakness
The Effect of Methylprednisolone on the Reversal Time of Rocuronium by Sugammadex in the Pediatric Patient Group
The aim of this study is to thoroughly investigate the interaction between methylprednisolone and sugammadex in the pediatric patient population.
- Trial name
- NCT06623370
- Testing
- methylprednisolone
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Muscle Weakness, Fatigue
Assessing Fatiguability of Tongue Muscles in MS
Multiple Sclerosis (MS) patients with subjective dysphagia will be tested for tongue strength fatigue using a strictly defined fatigue paradigm.
- Conditions
- Muscle Weakness, Fatigue, Multiple Sclerosis, Deglutition Disorders
- Trial name
- NCT03817073
- Testing
- Iowa Oral Performance Instrument (IOPI)
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Thomas More Kempen
Pompe Disease, Muscle Weakness
Safety and Effectiveness of Resistance Exercise Training in Patients With Pompe Disease.
The purpose of this research study is to determine if exercise will help improve muscle strength, endurance, and quality of life in individuals with Pompe disease.
- Trial name
- ExercisPompe (NCT02654886)
- Testing
- Resistance Exercise Training
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, Irvine
Neuromuscular Disease
Diagnostic Evaluation of Patients With Neuromuscular Disease
The objectives of this protocol are to: 1) screen patients with various neuromuscular disorders and facilitate their entry into appropriate research protocols; 2) help resolve puzzling diagnostic neuromuscular problems and train…
- Trial name
- NCT00015470
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke
THE EFFECT OF SURGICAL MASK AND N95 MASK USE ON SURGICAL SMOKE IN OPERATING ROOM NURSES
This study was conducted to compare the effect of surgical mask and N95 mask use on physical symptoms due to surgical smoke in operating theatre nurses.
- Conditions
- Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke, Headache, Dizziness
- Trial name
- NCT07404956
- Testing
- Surgical Mask, N95 Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Pompe's Disease
Prevalence of Pompe's Disease in Respiratory Clinics
Pompe's disease is a very rare condition which causes weakness of the respiratory muscles and may therefore cause symptoms of breathlessness or even respiratory failure, requiring the use of a ventilator at night.
- Trial name
- PURF (NCT02527239)
- Testing
- Prospective observational study
- Volunteers
- 400 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Cancer, Cancer Cachexia
Effects of WB-EMS and Dietetic Treatment on Cancer Patients
This study evaluates the effects of a 12-week whole-body electromyostimulation (WB-EMS) training combined with individualized nutritional support on body composition, muscle strength and function and quality of life of patients…
- Conditions
- Cancer, Cancer Cachexia, Weight Loss, Muscle Loss
- Trial name
- NCT02293239
- Testing
- Whole-Body Electromyostimulation (WB-EMS)
- Where
- Germany
- Volunteers
- 278 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Intensive Care Unit Syndrome, Intensive Care Neuropathy
Recovery From ICUAW Following Severe Respiratory and Cardiac Failure
To observe and identify determinants of recovery from intensive care unit-acquired weakness (ICUAW) following a severe cardiorespiratory failure requiring extra-corporeal membrane oxygenation (ECMO).
- Conditions
- Intensive Care Unit Syndrome, Intensive Care Neuropathy, Intensive Care (ICU) Myopathy, Acute Respiratory Distress Syndrome
- Trial name
- CLEVERER (NCT03753412)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Barts & The London NHS Trust
Gait, Hemiplegic, Stroke
Visual Observation Scale for the Upper Limb During Walking in Patients After Stroke.
For several years now, it has been demonstrated that the upper limb plays an important role in the function of an efficient and balanced gait pattern in healthy adults.
- Conditions
- Gait, Hemiplegic, Stroke, Upper Extremity Paresis
- Trial name
- NCT05128370
- Testing
- Visual observation of arm swing during walking
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- University Hospital, Ghent
Hand Function, Stroke
TheraBracelet Phase I
This project aims to test a new technology that may improve hand function impaired from a stroke, thereby improving independence and quality of life.
- Conditions
- Hand Function, Stroke, Upper Extremity, Hemiparesis
- Trial name
- NCT03318341
- Testing
- Real Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- TheraBracelet, Inc.