Clinical trials: Muscle Weakness | Patient
Muscle Weakness
Evaluation of Muscle Strength by Transcutaneous Electrical Stimulation
Acquired Neuromyopathy of Resuscitation (NMAR) is a common condition. Its diagnosis is difficult and often late because it is based on a clinical assessment of muscle strength (MRC score) requiring the patient to be awake and…
- Trial name
- STRENGTH-ICU (NCT03270163)
- Testing
- Transcutaneous electrical stimulation, Magnetic stimulation, ultrasound measurement
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Hemiparesis
Efficacy of Tele-rehabilitation Intervention on Hand, Cognitive Functions & Depression of Hemiparetic Patients
Information and communication technologies (ICT) are used in telerehabilitation to deliver rehabilitation treatments to patients in their homes or other locations.
- Trial name
- NCT06997978
- Testing
- Tele-rehabilitation, Hand rehabilitation program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ahmed Alshimy
Stroke, Biofeedback
Biofeedback Gait Training by Target Biomechanical Parameters in the Early Recovery Period of Stroke
Single-blinded controlled clinical trial. Biofeedback training courses based on target biomechanical gait parameters are being studied.
- Conditions
- Stroke, Biofeedback, Gait, Hemiplegic, Gait Training
- Trial name
- TargetGait (NCT06299943)
- Testing
- Biofeedback gait training by biomechanical target parameter
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Neuromuscular Disorders
Screening Questionnaire for Respiratory Muscle Weakness and Sleep-disordered Breathing in Neuromuscular Disorders
It is the aim of this project to develop and validate a German language screening questionnaire for symptoms of respiratory muscle weakness and sleep-disordered breathing (SDB) in patients with neuromuscular disorders.
- Trial name
- NCT02833168
- Testing
- patient-filled questionnaires, spiromanometry
- Where
- 2 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Universität Münster
Stroke, Parkinson's Disease
Inpatient Physical Activity Function Through Enhanced Participation Levels in Animal-Assisted Therapy Programs
Thousands of canines are used for therapy in health care centers throughout the United States as part of a volunteer therapy team, yet little is known about the outcomes provided by these teams.
- Conditions
- Stroke, Parkinson's Disease, Muscle Weakness
- Trial name
- NCT02606006
- Testing
- Canine Animal-Assisted Therapy, Standard of Care Physical Therapy
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Muscular Dystrophies
Study of Albuterol and Oxandrolone in Patients With Facioscapulohumeral Dystrophy (FSHD)
This is a study to determine whether albuterol or oxandrolone, alone or in combination, are able to increase strength and muscle mass in patients with FSHD.
- Trial name
- NCT00027391
- Testing
- Albuterol, Oxandrolone
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- FDA Office of Orphan Products Development
Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis), Gait Disorder
Isokinetic Strength Training in Hemiparetic Patient With Knee Extension Thrust
The purpose of this study is to assess the impact of an isokinetic strength training of knee flexor and extensor muscles on walking performance in hemiparetic patients with knee extension thrust.
- Trial name
- ISOWALK (NCT05887440)
- Testing
- isokinetic strength training of knee extensor and flexor muscles
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Rennes University Hospital
Muscle Weakness
Electromyography in Patients on Chronic Pyridostigmine Therapy
We intend to measure evoked EMG at two sites in subjects who are chronically taking pyridostigmine.
- Trial name
- NCT02364180
- Testing
- Electromyography (EMG)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Toledo Health Science Campus
Stroke, Upper Extremity Paresis
The Efficacy of Upper Limb Rehabilitation With Exoskeleton in Patients With Subacute Stroke.
Loss of arm function is a common and distressing consequence of stroke. Neurotechnology-aided rehabilitation could be a promising approach to accelerate the recovery of upper limb functional impairments.
- Trial name
- PowerUPS-REHAB (NCT04697368)
- Testing
- Exoskeleton-Assisted Upper Limb Rehabilitation, Traditional Upper Limb Rehabilitation
- Where
- 7 sites in Italy
- Volunteers
- 94 people
- Sponsor
- IRCCS San Raffaele Roma
Knee Osteoarthritis, Knee Arthritis
Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy
This is a randomized control trial to determine if there is a measurable change in voluntary quadriceps activation, RTD, pain, and function before and after a single session of manual physical therapy.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity
- Trial name
- NCT04234282
- Testing
- Manual Physical Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jennifer Moreno Clinic
Progressive Supranuclear Palsy, Dementia
Efficacy Study for Treatment of Dementia in Progressive Supranuclear Palsy
to show that 1. patients improve and stabilize after 12 -24 week treatment with rivastigmine in memory function 2. use of rivastigmine has a positive effect on apathy in PSP patients 3.
- Trial name
- psp (NCT00522015)
- Testing
- rivastigmine
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Tuebingen
COPD (Chronic Obstructive Pulmonary Disease), Muscle Weakness | Patient
Floor-Lift Series Pulmonary Rehabilitation for COPD: Short- and Long-Term Outcomes in a North African Setting
Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and functional disability, with pulmonary rehabilitation (PR) representing one of the most effective non-pharmacological interventions.
- Trial name
- FLS (NCT07277855)
- Testing
- Floor-Lift Series (FLS) Pulmonary Rehabilitation Program
- Where
- Algeria
- Volunteers
- 16 people
- Sponsor
- Benazzouz Redouene Sid Ahmed
Sarcopenia, Stroke, Acute
Effects of Mobility Dose on Discharge Disposition in Critically Ill Stroke Patients
The primary aim of the study is to assess the mobility dose in neurocritical care patients with ischemic stroke or intracranial hemorrhage and its effects on discharge disposition and patient outcomes.
- Conditions
- Sarcopenia, Stroke, Acute, Muscle Weakness, Critical Illness
- Trial name
- NCT03347656
- Where
- 3 sites in United States, Germany
- Volunteers
- 164 people
- Sponsor
- Beth Israel Deaconess Medical Center
Weaning Failure
Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU
Mechanical ventilation is a life-saving treatment frequently applied in intensive care unit (ICU). Nonetheless, by putting at rest the respiratory muscles, it can lead to respiratory muscle weakness and atrophy, which are…
- Trial name
- TrainToWean (NCT04658498)
- Testing
- Procedure: Usual Care (UC), Procedure: UC + HI-IMT
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- KU Leuven
Knee Osteoarthritis
Hip Abductor Strengthening Exercises in Knee Osteoarthritis
The aim of this randomized controlled trial is to find the effect of hip abductor strengthening exercises on pain, range of motion, functional disability and balance in patient with knee osteoarthritis.
- Trial name
- NCT06845657
- Testing
- Hip Abductor Strengthening Exercises, Conventional Treatment
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Neuromuscular Diseases, Hemiparesis
Validation Study of Posturology Platforms for Evaluating Postural Control of Hemiparetic and Neuro-muscular Patients
The instrumental evaluation of standing postural control by posturographic analysis supplements the clinical evaluation and, as such, is recommended by the French National Authority for Health (HAS 2007).
- Conditions
- Neuromuscular Diseases, Hemiparesis, Charcot-Marie-Tooth Disease
- Trial name
- KPLATES (NCT04283175)
- Testing
- Posturological examination on KPlates and AMTI platforms, Berg Balance Scale (BBS)
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cystic Fibrosis
1STST and Muscle Weakness in CF Patients
The investigators know that peripheral muscle weakness and exercise intolerance are prevalent (56%) in cystic fibrosis (Trooster et al, 2009). Physical inactivity is likely to be an important underlying factor.
- Trial name
- NCT03117764
- Testing
- Microfet Dynamometer, 1 minute sit to stand test, Accelerometer
- Where
- Belgium
- Volunteers
- 81 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Muscle Weakness, Weaning Failure
Abdominal Muscle Thickness in Mechanically Ventilated Patients
The purpose of the study is to determine to what extent the abdominal muscles contribute to airway pressure, in order to investigate the correlation between muscles weakness and extubation outcome in mechanically ventilated…
- Trial name
- NCT03567564
- Testing
- Abdominal muscles ultrasound
- Where
- 2 sites in Canada, Italy
- Volunteers
- 35 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Intensive Care Unit Acquired Weakness, Muscle Weakness
Early Assessment of Quadriceps Muscle Recovery by Dynamometry and 3D Ultrasound in Intensive Care Patients Under Invasive Mechanical Ventilation
Patients in intensive care often develop acquired muscle weakness (ICUAW or Intensive Care Unit Acquired Weakness) due to immobilization and muscle atrophy.
- Trial name
- DYNAMOREA (NCT07069959)
- Testing
- Early assessment of quadriceps muscle strength
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Stroke, Hemiparesis
EEG Brain-Machine Interface Control of an Upper-Limb Robotic Exoskeleton for Robot-Assisted Rehabilitation After Stroke
The goal of this study is to develop a clinically feasible, low-cost, nonsurgical neurorobotic system for restoring function to motor-impaired stroke survivors that can be used at the clinic or at home.
- Trial name
- NeuroExo (NCT05374486)
- Testing
- NeuroExo co-robot neurorehabilitation system
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Houston