Clinical trials: Muscle Weakness | Patient
Post-stroke Hemiparetic Patients (at Least 6 Months Post Stroke), Age Between 18-75 Years
Evaluation of the Effects of Rehabilitation Using the "Wii" on Upper Limb Kinematics in Chronic Stroke Patients.
The purpose of this study is to evaluate changes in strategies of hemiparetic upper limb movement in chronic stroke patients following rehabilitation using the "Nintendo Wii".
- Trial name
- WII (NCT01806883)
- Testing
- WII Rehabilitation, Traditional rehabilitation
- Where
- France
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Hemiparesis
Quadriceps Muscle Activity and Gait Kinematics in Patients With Post-Stroke Stiff-Knee Gait Compared With Healthy Controls
Stiff-knee gait (SKG) is a frequent gait abnormality in people with post-stroke hemiparesis and is characterized by insufficient knee flexion during the swing phase of walking.
- Trial name
- FW QUADRI (NCT07857967)
- Where
- Luxembourg
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Frédéric Chantraine
Mechanical Ventilation Complication, Neuromuscular Electrical Stimulation
NMES to Prevent Respiratory Muscle Atrophy in Mechanically Ventilated Patients
Patients requiring prolonged time on the ventilator are susceptible to a wide range of clinical complications and excess mortality. It is therefore imperative for them to wean at the earliest possible time.
- Conditions
- Mechanical Ventilation Complication, Neuromuscular Electrical Stimulation, Muscle Weakness
- Trial name
- NCT03453944
- Testing
- VentFree prototype (VF03-K) active stimulation
- Where
- 3 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Nijmegen
Physiology
Physiopathology of Lower Cortical Activation in COPD Patients: Contribution of Cortical Neuromodulation
Patients with COPD have lower cortical activation and higher cortical inhibitory levels. The purpose of this study is to test the reversibility the lower cortical activation by counterbalancing the increased cortical inhibitory…
- Trial name
- NCT03368703
- Testing
- Anodal transcranial direct-current-stimulation
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- 5 Santé
Stroke, Upper Extremity Paresis
NIBS With mCIMT for Motor and Functional Upper Limb Recovery in Stroke Patients.
Stroke is one of the leading causes of serious long-term impairment. According to the estimates, 12,500 people suffer a new or recurrent ischemic stroke in Chile annually, which shows the magnitude of the problem.
- Conditions
- Stroke, Upper Extremity Paresis, Electric Stimulation, Occupational Therapy
- Trial name
- NCT03452254
- Testing
- Active Bihemispheric Transcranial direct current Stimulation, Modified Constraint Induced Movement Therapy
- Where
- 2 sites in Chile
- Volunteers
- 70 people
- Sponsor
- University of Chile
Generalized Myasthenia Gravis
A Safety and Tolerability Study of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness.
This is a Long-Term, Single-Arm, Open-Label, Multicenter Phase 3 follow-on trial of the ARGX-113-1704 study to evaluate the safety and tolerability of ARGX-113 in patients with gMG.
- Trial name
- ADAPT+ (NCT03770403)
- Testing
- ARGX-113
- Where
- 52 sites in United States, Belgium and 13 more
- Volunteers
- 151 people
- Sponsor
- argenx
Stroke, Motor Disorders
Functional Proprioceptive Stimulation of the Upper Limbs in Stroke Patients
Parallel-group, single-blinded controlled clinical trial. The study involved stroke patients (no more than 3 points on a scale Rankin) dived of the control group and experimental group.
- Conditions
- Stroke, Motor Disorders, Upper Extremity Paresis, Muscle Weakness
- Trial name
- NCT06143475
- Testing
- FPS group, Conventional therapy group
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Critical Illness, Intensive Care (ICU) Myopathy
Muscle Dysfunction in Critical Illness
Patients surviving critical illness suffered significant skeletal muscle dysfunction and weakness that impacts their functionality and independence.
- Conditions
- Critical Illness, Intensive Care (ICU) Myopathy, PICS, Muscle Weakness
- Trial name
- NCT03717831
- Testing
- Observational study of standard of care
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Kentucky
Stroke Rehabilitation, Cerebrovascular Stroke
Error Augmentation Motor Learning Training Approach in Stroke Patients
Deficits in upper limb (UL) functional recovery persist in a large proportion of stroke survivors. Understanding how to obtain the best possible UL recovery is a major scientific, clinical and patient priority.
- Conditions
- Stroke Rehabilitation, Cerebrovascular Stroke, Muscle Spasticity, Upper Extremity Paresis
- Trial name
- NCT04378946
- Testing
- Intensive physical rehabilitation type training, Robotic system for supporting and monitoring arm motion, Actigraph Activity Monitor
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- McGill University
Chronic Thromboembolic Pulmonary Hypertension, Inspiratory Muscle Training
Inspiratory Muscle Training in Pulmonary Hypertension
Inspiratory muscle training for 8 weeks in patients with pulmonary hypertension.
- Conditions
- Chronic Thromboembolic Pulmonary Hypertension, Inspiratory Muscle Training, Inspiratory Muscle Weakness, Pulmonary Arterial Hypertension
- Trial name
- NCT03102294
- Testing
- inspiratory muscle training
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Federal University of São Paulo
Subacromial Impingement Syndrome, Musculoskeletal Diseases
Comparison of Two Different Treatment Methods
A number of previous studies investigated the effects of kinesiotaping (KT) in subacromial impingement syndrome (SIS).
- Conditions
- Subacromial Impingement Syndrome, Musculoskeletal Diseases, Musculoskeletal Injury, Musculoskeletal Pain
- Trial name
- NCT05071469
- Testing
- Kinesiotaping, Mulligan Mobilization Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Banu BAYAR
Hemiparesis
Outcome Measures of Modified Constraint Induced Movement Therapy Versus Dual Task Training on Upper Extremity and Cognitive Functions in Patients With Hemiparesis
All stroke patients were assessed via isokinetic dynamometer, Montreal cognitive assessment scale (MOCA) and Fugl Myer Upper extremity (FMUE) before and after the treatment program.
- Trial name
- NCT06457022
- Testing
- Modified Constraint Induced Movement therapy, Dual task training in the form of cognitive - motor task, Conventional physiotherapy rehabilitation program
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Ahmed Alshimy
Knee Arthroscopic Surgery, Arthrogenic Muscle Inhibition
Blood Flow Restriction Training in Knee Arthropathy
Arthrogenic muscle inhibition (AMI) is the key neurophysiological cause of impeding quadriceps activation following anterior cruciate ligament reconstruction (ACLR).
- Conditions
- Knee Arthroscopic Surgery, Arthrogenic Muscle Inhibition, Quadriceps Muscle Weakness
- Trial name
- NCT07837154
- Testing
- Blood flow restriction training with 60%-80% occlusion
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Yuxiu Ji
Hypertension, Pulmonary
Effects of Inspiratory Muscle Training in Patients With Pulmonary Hypertension
This study aims to determine the possible effects of inspiratory muscle training on cardiovascular, respiratory, physical and psychosocial functions in patients with PH.
- Trial name
- NCT04152187
- Testing
- Inspiratory muscle training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Dokuz Eylul University
Stroke, Upper Extremity Paresis
Effects of Bihemispheric Transcranial Direct Current Stimulation on Motor Function in Stroke Patients
Motor impairment (impairment of movement) due to stroke is one of the leading disabilities in adults. In addition to established means of facilitating motor recovery after stroke such as physical and occupational therapy, a…
- Conditions
- Stroke, Upper Extremity Paresis, Transcranial Direct Current Stimulation
- Trial name
- NCT03839316
- Testing
- tDCS
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Baskent University
Bariatric Surgery Candidate, Muscle Weakness
Inspiratory Muscle Training and Pulmonary Function in Patients Submitted to Bariatric Surgery
Obesity is defined as a body mass index greater than or equal to 30 kg / m2 and represents a public health problem that affects the world population.
- Conditions
- Bariatric Surgery Candidate, Muscle Weakness, Complication,Postoperative, Respiratory Muscle
- Trial name
- NCT05575089
- Testing
- Inspiratory muscle training - Powerbreath, Aerobic exercise in cycle ergometer, Deep breathing exercises
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Universidade Cidade de Sao Paulo
Cancer, Cancer Cachexia
Effects of WB-EMS and Specific Dietary Supplements on Cancer Patients
Patients suffering from cancer often experience a loss of muscle mass and strength during disease and its therapy. Muscle wasting is the main characteristic of the so-called cancer cachexia syndrome and responsible for many…
- Conditions
- Cancer, Cancer Cachexia, Weight Loss, Muscle Loss
- Trial name
- NCT03151291
- Testing
- β-hydroxy-β-methylbutyrate (HMB), L-carnitine (LC), Eicosapentaenoic acid (EPA)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Muscle Weakness
Effect of Mode of Femoral Nerve Analgesia on Quadriceps Muscle Strength
Quadriceps muscle strength is an important determinant of quality of recovery in elderly patients after total knee arthroplasty.
- Trial name
- NCT02007850
- Testing
- ropivacaine
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Seoul National University Hospital
Intensive Care Unit (ICU) Acquired Weakness (ICU - AW), Muscle Weakness
Nutrient Pattern Analysis in Critically Ill Patients (NAChO)
Little is known about nutritional Parameters that potentially influence the course of intensive-care unit acquired weakness (ICU - AW).
- Trial name
- NAChO (NCT02839018)
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Stroke, Hemiplegia
Effects of Intermitted Theta Burst Stimulation (iTBS) on Motor Recovery of Upper Extremity in Chronic Stroke Patients
This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of upper…
- Conditions
- Stroke, Hemiplegia, Hemiparesis After Stroke, Hand Functionality
- Trial name
- NIMBLE (NCT07073248)
- Testing
- Intermittent Theta Burst Stimulation
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Danderyd Hospital