Clinical trials: Muscle Weakness | Patient
Intensive Care Unit Acquired Weakness
Blood Flow Restriction Training for Mechanically Ventilated Patients With ICU-Acquired Weakness
Patients receiving mechanical ventilation in the intensive care unit (ICU) frequently develop ICU-acquired weakness - a condition marked by widespread muscle loss and weakness caused by prolonged bed rest, severe illness, and…
- Trial name
- BFRT-ICU (NCT07802743)
- Testing
- Blood flow restriction training, Standard ICU Care and Routine Rehabilitation
- Volunteers
- 120 people
- Sponsor
- Affiliated Hospital of Jining Medical University
Flat Feet, Flexible Flatfoot
Effect of Insole Added to Exercise in Patients With Bilateral Flexible Flatfoot
Pesplanus, commonly known as 'flatfoot,' is a common pathomechanical condition characterized by a lowered medial longitudinal arch (MLA) and exaggerated pronation.
- Conditions
- Flat Feet, Flexible Flatfoot, Balance; Distorted, Muscle Weakness
- Trial name
- NCT05056298
- Testing
- Custom made insole, Strengthening exercises of extrinsic foot muscles, Strengthening exercises of intrinsic foot muscles
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Horus University
Dermatomyositis, Polymyositis
Infliximab (Remicade ) to Treat Dermatomyositis and Polymyositis
This study will examine whether infliximab (Remicade ) is safe and effective for the treatment of dermatomyositis and polymyositis.
- Trial name
- NCT00033891
- Testing
- Infliximab
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Polyneuropathy
Muscular Electrostimulation of the Sedated and Mechanically Ventilated Critically Ill Patient. Analysis of the Effect on Acquired Muscular Weakness and Its Clinical Consequences.
Even 20-50% of patients under sedation and mechanical ventilation develops myopathy and / or neuropathy which difficulties both the process of extubation and the functional recovery.
- Trial name
- NCT02033057
- Testing
- Muscular electrostimulation and percutaneus muscular biopsy.
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Universitario La Fe
AD - Alzheimer's Disease, Sarcopenia
A Study of Silkworm Pupa Powder Intervention in the Nutritional Status of Patients With Alzheimer's Disease.
The goal of this clinical trial is to learn if silkworm pupa powder works to improve the nutritional status of Alzheimer's disease patients.
- Conditions
- AD - Alzheimer's Disease, Sarcopenia, Asthenia
- Trial name
- AD (NCT07059871)
- Testing
- Silkworm pupa powder
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Zhejiang Hospital
Intensive Care Unit Acquired Weakness, Intensive Care Unit (ICU) Acquired Weakness (ICU - AW)
Functional Assessment in Critically Ill Patients
This longitudinal, prospective observational study aims to evaluate functional status in critically ill adult patients in the Intensive Care Unit using the Chelsea Critical Care Physical Assessment Tool (CPAx).
- Trial name
- NCT07191743
- Where
- Brazil
- Volunteers
- 186 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Cerebrovascular Stroke, Muscle Weakness
Mirror Therapy and Cross-Education of Muscle Strength
This study was conducted to determine whether mirror therapy has an additive effect on cross-education of the strength of neuromuscular electrical stimulation (NMES) in patients with hemiplegia.
- Trial name
- NCT04887376
- Testing
- Mirror frame, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Muscle Weakness, Critical Illness
Critical Illness Neuromuscular Abnormalities in Neurocritical Care Patients
The aim of this research is to investigate critical illness neuromuscular abnormalities in neurocritical care patients.
- Trial name
- NCT00893633
- Where
- Russia
- Volunteers
- 135 people
- Sponsor
- Clinical Institute of the Brain, Russia
Stroke, Hemiplegia and Hemiparesis
The Efficacy of Additional Motor Training Dosage During the Early Stages Post Stroke on the Upper Extremity Recovery
Intervention abstract Background: Stroke is the leading cause of long-term disability, and the second leading cause of death in the western world.
- Trial name
- EFODIN (NCT07056049)
- Testing
- High dosage, high intensity motor rehabilitation
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Adi Negev-Nahalat Eran
Vocal Cord Paresis, Acquired Vocal Cord Palsy
The Incidence and Impact of Vocal Cord Dysfunction In Patients Undergoing Thoracic Surgery
Population-based single centre, blinded, prospective cohort study of the impact of recurrent laryngeal nerve (RLN) injury on Thoracic Surgery patients.
- Trial name
- NCT02996526
- Where
- Canada
- Volunteers
- 173 people
- Sponsor
- University of Manitoba
Muscle Weakness or Atrophy, Mechanical Ventilation Complication
NMES Role to Prevent Respiratory Muscle Weakness in Critically Ill Patients and Its Association to Changes in Myokines.
Particularly, muscle respiratory wasting will occur early (18 to 69 hours) in up to 60% of patients with mechanical ventilation (MV), leading rapidly to diaphragmatic weakness, which is associated with prolonged MV use, longer…
- Conditions
- Muscle Weakness or Atrophy, Mechanical Ventilation Complication, Electrical Stimulations
- Trial name
- NCT05536531
- Testing
- Neuromuscular electrical stimulation (NMES)
- Where
- Chile
- Volunteers
- 32 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Sepsis, Critical Illness
MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients
The goal of this clinical trial is to learn if a new medical device that sends electrical signals to the thigh muscles is safe and easy to use for people in the ICU (Intensive Care Unit) who are at risk of losing muscle strength.
- Conditions
- Sepsis, Critical Illness, ICU-acquired Muscle Weakness, ICU-acquired Weakness
- Trial name
- ICUAW (NCT07362862)
- Testing
- Electrical Muscle Stimulation System
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Health Discovery Labs
Heart Failure
Exercise Capacity and Fatigue in Heart Failure Patients With and Without Inspiratory Muscle Weakness
In patients with heart failure, diaphragm dysfunction contributes to decreased quality of life while simultaneously increasing morbidity and mortality.
- Trial name
- NCT06428227
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Gazi University
Neuromuscular Electrical Stimulation, Intensive Care Unit Acquired Weakness
Effects of Neuromuscular Electrical Stimulation on Muscle Mass and Strength in Critically Ill Patients After Cardiothoracic Surgery
The purposes of this study are 1) to determine whether neuromuscular electrical stimulation (NMES) is effective in preventing loss of muscle mass and strength and 2) to observe the time variation of MLT and strength from…
- Conditions
- Neuromuscular Electrical Stimulation, Intensive Care Unit Acquired Weakness, Muscle Wasting, Muscle Loss
- Trial name
- Catastim 2 (NCT02391103)
- Testing
- Compex 3 Professional (CefarCompex Medical AB) stimulator
- Volunteers
- 54 people
- Sponsor
- Medical University of Vienna
Pain, Soreness
Benefit of CoQ-10 in Patients on Statins
This study will investigate whether a supplement called co-enzyme Q10 can help ease or eliminate some of the side effects that result from taking statin medications.
- Conditions
- Pain, Soreness, Weakness, Fatigue
- Trial name
- CoQ-10 (NCT00997269)
- Testing
- Co-enzyme Q-10
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Stony Brook University
Stroke, Hemiparesis
Concomitant Application of TENS and NMES on Chronic Stroke
Stroke is a cerebrovascular disorder that can lead to permanent disability and a decline in quality of life. Chronic stroke patients often experience decreased balance control, which negatively affects activities of daily living…
- Trial name
- TENS NMES (NCT06619262)
- Testing
- Transcutaneous Electrical Nerve Stimulation, Neuromuscular and Muscular Electrical Stimulation, Exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Inflammatory Response, Weakness, Muscle
CORTERAS STUDY: The Effect of Corticosteroids on Early Recovery After Major Surgery in Elderly Patients
Major surgery induces a systemic inflammatory response, which can influence the post-operative morbidity, such as coagulation disorders and post-operative muscle weakness, hampering early recovery after surgery.
- Trial name
- CORTERAS (NCT05220319)
- Testing
- Methylprednisolone, NaCl 0.9%
- Where
- Belgium
- Volunteers
- 751 people
- Sponsor
- Ziekenhuis Oost-Limburg
Multiple Sclerosis, Muscle Weakness
Foot Muscles Training in Sclerosis
The study tries to assess the efficacy of an 8-week IFM training programme on stability in patients diagnosed with Multiple Sclerosis
- Conditions
- Multiple Sclerosis, Muscle Weakness, Training Group, Sensitivity
- Trial name
- NCT06665607
- Testing
- Intrinsic Mucle Training
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Inés Llamas-Ramos
Hemiparesis
Stability of Hemiparetic Patients During a Daily Complex Task
Among the repercussions of hemiparesis following stroke, disturbed stability is responsible for a high risk of falls. Picking up objects from the ground, frequently trained in rehabilitation due to its risk of falling and its…
- Trial name
- HemiSym (NCT07082036)
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
The Effectiveness of Novel Rehabilitation Device on Upper Limb Impairment Among Patients With Stroke
Usability and Effectiveness of a Novel Bilateral Upper Limb Training Device for Stroke Patients With Hemiparesis: A Preliminary Study
Background and Study Aims Stroke is a leading cause of long-term disability worldwide, affecting millions of individuals each year.
- Trial name
- Synslai (NCT06956677)
- Testing
- Novel UE rehabilitation device training, The UE functional training, Conventional occupational therapy
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- Chang Gung Memorial Hospital