Clinical trials: Musculoskeletal, open to volunteers
Femoro-acetabular Impingement
Single-center Comparative Study of Variation in Acetabular Anteversion According to Pelvic Tilt in Patients With Femoro-acetabular Impingement and Healthy Volunteers.
The main objective is to show that the upper acetabular anteversions calculated in standing, sitting, sitting hip in maximum flexion and supine positions are lower in patients with symptomatic DWI compared to healthy volunteers.
- Trial name
- VARIA-CFA (NCT05678894)
- Testing
- Scanner and EOS imaging
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Migraine in Children, Complex Regional Pain Syndromes
Supraspinal Processing of Sensory Aspects of Pain
The goal of this basic science study is to learn about the brain mechanisms of chronic pain across different chronic pain syndromes in pediatric patients.
- Conditions
- Migraine in Children, Complex Regional Pain Syndromes, Musculoskeletal Pain, Functional Abdominal Pain Syndrome
- Trial name
- SCP (NCT05814497)
- Testing
- Multisensory Task, Graphesthesia, Divided attention
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Myositis, Dermatomyositis
Environmental Risk Factors for the Anti-synthetase Syndrome
Background: Like other complex diseases, autoimmune diseases are the result of numerous causes, including genetic and environmental factors.
- Conditions
- Myositis, Dermatomyositis, Polymyositis, Juvenile Dermatomyositis
- Trial name
- NCT01276470
- Where
- 8 sites in United States
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Bone Loss, Jaw, Edentulous
Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
The objective of this study is to test the bone formation capacity of a 3D printed scaffold with a plastic material called Polycaprolactone (PCL), compared to the use of synthetic bone grafts, for bone formation in the maxilla or…
- Conditions
- Bone Loss, Jaw, Edentulous, Edentulous Mouth, Jaw Fractures
- Trial name
- OSTEOPRINT (NCT06773923)
- Testing
- PCL Scaffold, PTFE + Bio-Oss®
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Inclusion Body Myositis
IBM Dietary Surveillance Study
The goal of this observational study is to understand how diet may influence the disease characteristics of inclusion body myositis (IBM).
- Trial name
- NCT07535996
- Testing
- Whole-Body Dual-Energy X-ray Absorptiometry, Anthropometry, Capillary Blood Sampling
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University
Bone Resorption
Guided Bone Regeneration Using Fixed vs Non-Fixed Resorbable Collagen Membranes
The aim of this clinical trial is to compare the horizontal bone gain when grafting a bone substitute with non fixed resorbable collagen membranes (control group), versus fixed resorbable collagen membranes (test group) in…
- Trial name
- NCT06334159
- Testing
- Horizontal GBR with the use of non-resorbable pins for the stabilization of the collagen membrane, Horizontal GBR without the use of non-resorbable pins for the stabilization of the collagen membrane
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia
Palliative Care Needs of Children With Rare Diseases and Their Families
The palliative care needs of family caregivers of children with rare diseases and their children are largely unmet, including the need for support to prepare for future medical decision making.
- Conditions
- Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia, Asparagine Synthetase Deficiency, CHARGE Syndrome
- Trial name
- FACE-Rare (NCT06938542)
- Testing
- Family Centered pediatric palliative care for family caregivers of children with rare diseases.
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Shoulder Impingement Syndrome, Rotator Cuff Injuries
The Role of Pectoralis Minor Tightness in the Development of Rotator Cuff Tears
This study investigates whether tightness of a small chest muscle called the pectoralis minor is associated with the development of partial rotator cuff tears in the shoulder.
- Conditions
- Shoulder Impingement Syndrome, Rotator Cuff Injuries, Pectoralis Minor Tightness, Pectoralis Minor Muscle Tension
- Trial name
- PMinor-Rotator (NCT07228936)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gazi University
Adolescent Idiopathic Scoliosis (AIS)
Investigation of Shoulder Position, Upper Extremity Proprioception, and Function in Adolescents With Idiopathic Scoliosis Using Braces
This study aims to investigate the effects of brace use on shoulder position, upper extremity proprioception, and upper extremity function in adolescents with idiopathic scoliosis.
- Trial name
- NCT06904157
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gözde Yagci (Gür)
Muscular Dystrophies, Myopathies
Observational Study to Observe Variations of Gait Parameters in Patients With Neuromuscular Diseases
This study has the general objective of observing walking parameters during a clinical test to objectively estimate fatigue in patients with neuromuscular diseases.
- Conditions
- Muscular Dystrophies, Myopathies, Spinal Muscular Atrophy (SMA), Charcot Marie Tooth Disease
- Trial name
- NCT06666816
- Testing
- inapplicable
- Where
- 2 sites in Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Axial Spondyloarthritis and Ankylosing Spondylitis
Effects of Land- and Water-Based Exercise in Axial Spondyloarthritis
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by pain, morning stiffness, restricted spinal mobility, and systemic manifestations.
- Trial name
- NCT07833033
- Testing
- Land-Based Combined Exercise Program, Aquatic Combined Exercise Program, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Izmir University of Economics
Work-Related Musculoskeletal Disorders
The Impact of Back-supporting Exoskeletons for Manual Order Picking in Danish Warehouses - The RELAX Project
This study investigates the long-term effects of implementing a passive back-support exoskeleton during manual order-picking work in a real-world warehouse environment.
- Trial name
- RELAX (NCT07561112)
- Testing
- Use of an occupational passive back-exoskeleton
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Cerebral Palsy, Muscle
How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery.
Cerebral palsy (CP) is a motor disorder caused by an injury to the immature brain. Even though the brain damage does not change, children with CP will have progressively weaker, shorter and stiffer muscles that will lead to…
- Conditions
- Cerebral Palsy, Muscle, Muscle Contracture, Muscle Spasticity
- Trial name
- CPTDBiopsy (NCT05506228)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eva Ponten
Osteoarthitis, Osteoporosis
Evaluation of Musculoskeletal Aging and Related Disorders Via Advanced Clinical Imaging
Study Overview This clinical research focuses on the development and validation of a multimodal artificial intelligence (AI) platform designed for the automated diagnosis and precise staging of two major musculoskeletal…
- Trial name
- NCT07474571
- Testing
- No Interventions
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Lateral Epicondylitis, Lateral Elbow Tendinopathy (Tennis Elbow)
Ultrasonographic Examination of Other Enthesitis Sites in Patients With Lateral Epicondylitis
Lateral epicondylitis (LE) is the tendinopathy of the common extensor tendon. Although exact etiology remains unclear, it is believed to be caused by overuse.
- Trial name
- NCT07314840
- Testing
- Madrid Sonographic Enthesitis Index
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Education, Joint Diseases
The Application of Artificial Intelligence in Wrist and Hand Joint Ultrasound
1. To develop an AI system that can automatically identify standard sections and save images during wrist and hand joint ultrasound scans, while labeling key anatomical structures. 2.
- Trial name
- NCT06883669
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Back Pain, Low Back Pain
Low Back and Neck Pain in Nursing Students at The University of The West Indies
The purpose of this study is to identify the prevalence of neck and low back pain in nursing students enrolled at the University of the West Indies, Mona; to assess their knowledge, attitude and practice of good spine health and…
- Conditions
- Back Pain, Low Back Pain, Musculoskeletal Pain, Neck Pain
- Trial name
- NCT07167888
- Testing
- Clinical Control Group (Group A), Spine Exercise Program (Group B)
- Where
- Jamaica
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Centronuclear Myopathy
Multispectral Optoacoustic Tomography for Advanced Imaging of Centronuclear Myopathy
Twenty patients with centronuclear myopathy and twenty age- and sex-matched, muscle-healthy controls will undergo diagnostic examination.
- Trial name
- MOSAIC (NCT07021820)
- Testing
- MSOT
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Congenital Adrenal Hyperplasia, Hypogonadotropic Hypogonadism
Growing up With the Young Endocrine Support System (YESS!)
Transition from paediatric to adult endocrinology is a challenge for adolescents, families and doctors. Up to 25% of young adults with chronic endocrine disorders are lost to follow-up ('drop-out') once the young adult moves out…
- Conditions
- Congenital Adrenal Hyperplasia, Hypogonadotropic Hypogonadism, Growth Hormone Deficiency, Combined Pituitary Hormone Deficiency
- Trial name
- YESS (NCT04252001)
- Testing
- YESS! game, Snake '97, Transition-toolkit
- Where
- 7 sites in Belgium, Netherlands and 2 more
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- dr. Laura C. G. de Graaff-Herder
Bruxism, Pelvic Pain
Bruxism, Pelvic Pain, Erectile Dysfunction, and Anxiety in Young Adult Men
Bruxism is a parafunctional activity characterized by clenching or grinding of the teeth during wakefulness or sleep. Increasing evidence suggests that bruxism is not only related to orofacial structures but may also be…
- Conditions
- Bruxism, Pelvic Pain, Myofascial Pain - Dysfunction Syndrome of TMJ, Myofascial Pain Dysfunction Syndrome
- Trial name
- NCT07469345
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Akdeniz University