Clinical trials: Musculoskeletal Complication
Postoperative Pain
Comparison of the Efficacy of PENG Block in Combination With LFCN Block and Wound Infiltration
The ultrasound-guided approach for the blockade of articular branches of femoral and obturator nerves, pericapsular nerve group (PENG) block, is an effective method for postoperative analgesia in hip surgeries.
- Trial name
- NCT04681222
- Testing
- LFCN, Wound infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Derince Training and Research Hospital
Urolithiasis and Aging, Renal Calcul and Metabolic Diseases
Metabolic Assessment of Aging Men With Urinary Lithiasis
Urinary lithiasis is a common disease on young adults, but not so far on aging people. Nowadays, the investigators are seeing a gradative growth on men above sixty years old, mainly in industrialized countries.
- Conditions
- Urolithiasis and Aging, Renal Calcul and Metabolic Diseases, Urolithiasis and Osteoporosis
- Trial name
- NCT01246531
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Total Parenteral Nutrition-induced Cholestasis, Cholestasis
Compassionate Use of Omegaven in Children
This is a single-assignment study to evaluate whether Omegaven (IV fish oil) is effective at treating liver disease in children on long-term IV nutrition.
- Conditions
- Total Parenteral Nutrition-induced Cholestasis, Cholestasis, Short Bowel Syndrome, Gastroschisis
- Trial name
- NCT02370251
- Testing
- Omegaven
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Oklahoma
Chronic Kidney Diseases, Bone Loss
Bone in CKD Alkali Response (BICARb Pilot Trial)
The goal of this clinical trial is to test whether potassium citrate improves skeletal health in adults and children with chronic kidney disease.
- Trial name
- BICARb (NCT05918029)
- Testing
- Potassium Citrate Extended Release Oral Tablet, Potassium Citrate and Citric Acid Oral Solution
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Albert Einstein College of Medicine
Renal Osteodystrophy
Renal Osteodystrophy: A Fresh Approach
There are two major goals of this project: 1. Comparison of DXA and QCT for diagnosis of bone loss in CKD-5 patients and determination of the prevalence of low bone turnover in CKD-5 patients with bone loss. 2.
- Trial name
- NCT00859612
- Where
- United States
- Volunteers
- 464 people
- Sponsor
- Hartmut Malluche, MD
Autoimmune Diseases, Cardiovascular Disorders
Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
This multi-arm, multi-site study investigates the safety, tolerability, and efficacy of stem cell therapy for the treatment of various acute and chronic conditions.
- Conditions
- Autoimmune Diseases, Cardiovascular Disorders, Diabetes Complications, Integumentary Disease
- Trial name
- NCT04684602
- Testing
- PrimePro™/ PrimeMSK™
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Thomas Advanced Medical LLC
Dental Implant Failure, Periodontal Bone Loss
A Retrospective Analysis of Failures of Oral Implants
The purpose of this retrospective study is to investigate and identify factors associated with the failure of dental implants within the population rehabilitated with dental implants at the Folktandvården Specialistklinik in…
- Trial name
- NCT02369562
- Testing
- Evaluation of the failure rate of dental implants
- Where
- Sweden
- Volunteers
- 2,670 people, healthy volunteers welcome
- Sponsor
- Malmö University
End Stage Renal Disease, Hyperparathyroidism, Secondary
Mineral and Bone Disorders Outcomes in Stage 5D of Chronic Kidney Disease
The MBD-5D is a prospective observational study with a case-cohort and a cohort design. Eligible patients are receiving hemodialysis and have secondary hyperparathyroidism.
- Trial name
- MBD-5D (NCT00995163)
- Where
- Japan
- Volunteers
- 8,020 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Pelvic Floor Disorders, Urinary Incontinence
Maternal Musculoskeletal Factors of the Hip, Lumbopelvic, Abdominal and Pelvic Floor Regions and Their Association With Mode of Delivery and Postpartum Pelvic Floor Dysfunction
This prospective observational cohort study aims to investigate the association between maternal musculoskeletal factors of the hip, lumbopelvic, abdominal, and pelvic floor regions and childbirth outcomes, as well as their…
- Conditions
- Pelvic Floor Disorders, Urinary Incontinence, Perineal Trauma, Pelvic Floor Dysfunction
- Trial name
- NCT07478159
- Testing
- Maternal Musculoskeletal Assessment
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Chronic Low Back Pain, Sacroiliitis
Effectiveness of Ultrasound Guided Platelet Rich Plasma Injections in the Sacroiliac Joint
This prospective study will be quantitatively analyzing the effectiveness of platelet-rich-plasma (PRP) injections into the sacroiliac (SI) joint in relieving sacroiliitis and low back pain originating from the SI joint.
- Conditions
- Chronic Low Back Pain, Sacroiliitis, Sacroiliac; Backache, Platelet Rich Plasma
- Trial name
- NCT03122119
- Testing
- Platelet Rich Plasma Joint Injection
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Star Spine and Sport
Renal Osteodystrophy
Cholecalciferol Versus Doxercalciferol in the Treatment of Secondary Hyperparathyroidism in Chronic Kidney Disease
The majority of patients with moderate to severe chronic kidney disease (CKD) (stages 3 and 4) develop secondary hyperparathyroidism (2°HPT), but the optimal therapy to control hyperparathyroidism in this group is unknown.
- Trial name
- NCT00285467
- Testing
- doxercalciferol, Cholecalciferol
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Indiana University
Hip Osteoarthritis, Pain, Acute
Lumbar Plexus and Suprainguinal Fascia Iliaca Blocks For Total Hip Replacement
The nerves from lumbar plexus (LP) are the current target to achieve analgesia after a total hip arthroplasty (THA). Lumbar plexus block (LPB) is an alternative that provides optimal postoperative analgesia.
- Conditions
- Hip Osteoarthritis, Pain, Acute, Pain, Postoperative, Opioid Use
- Trial name
- NCT03744065
- Testing
- lumbar plexus block, suprainguinal fascia iliaca block
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University of Chile
X Linked Hypophosphatemic Rickets
Growth Hormone Treatment in Children With Hypophosphatemic Rickets
This study evaluates the effect on height of a two year treatment with growth hormone in 19 children with X linked hypophosphatemic rickets.
- Trial name
- GH-XLH (NCT02720770)
- Testing
- norditropine simplex
- Volunteers
- 19 people
- Sponsor
- Bicetre Hospital
Spinal Stenosis, Spondylolisthesis
Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures
The purpose of this retrospective data review is to evaluate the health economic drivers and complications of two surgical procedures: transsacral lumbar interbody fusion and transforaminal lumbar interbody fusion when used in…
- Conditions
- Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease (DDD)
- Trial name
- NCT02171169
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Baxano Surgical, Inc.
Freeman-Sheldon Syndrome, Arthrogryposis Distal Type 2A
Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome
Freeman-Sheldon syndrome (FSS) is a rare muscle disorder present before birth, involving primarily problems of the face and skull and the hands and feet.
- Conditions
- Freeman-Sheldon Syndrome, Arthrogryposis Distal Type 2A, Whistling Face Syndrome, Craniocarpotarsal Dysplasia
- Trial name
- STOP-FSS (NCT01144741)
- Testing
- PTSD Checklist-Civilian (PCL-C), Modified Flanagan Quality of Life Scale, Center for Epidemiologic Studies Depression Scale (CES-D)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Freeman-Sheldon Research Group, Inc.
Fraser Syndrome, Fryns Syndrome
Genetic Analysis of Fraser Syndrome and Fryns Syndrome
This study will examine blood or other tissue samples from patients with Fraser syndrome and patients with Fryns syndrome to try to identify the gene responsible for these diseases.
- Conditions
- Fraser Syndrome, Fryns Syndrome, Chromosomal Abnormalities, Abnormalities, Multiple
- Trial name
- NCT00032877
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Cancer, Pancreatic Cancer
9-ING-41 in Patients With Advanced Cancers
GSK-3β is a potentially important therapeutic target in human malignancies. The Actuate 1801 Phase 1/2 study is designed to evaluate the safety and efficacy of 9-ING-41, a potent GSK-3β inhibitor, as a single agent and in…
- Conditions
- Cancer, Pancreatic Cancer, Sarcoma, Renal Cancer
- Trial name
- NCT03678883
- Testing
- 9-ING-41, Gemcitabine - 21 day cycle, Doxorubicin.
- Where
- 66 sites in United States, Belgium and 5 more
- Volunteers
- 350 people
- Sponsor
- Actuate Therapeutics Inc.
Diabetic Neuropathy, Arthritis
Effect of Holofiber Socks and Bedding on Pain and Quality of Sleep in Subjects With Chronic Foot Pain
This study is designed to assess the effects of socks and bedding materials on foot pain, the level of blood oxygen existing in the feet and quality of sleep in subjects who have chronic foot pain from either diabetic neuropathy…
- Conditions
- Diabetic Neuropathy, Arthritis, Peripheral Arterial Disease, Plantar Fasciitis
- Trial name
- NCT00458497
- Testing
- Holofiber fabric, PET fabric
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Southern California Institute for Research and Education
End Stage Renal Disease
Elbow Pain in Hemodialysis Patients and Its Effect on Daily Living Activities of the Patients
The study will include the patients undergoing hemodialysis.
- Trial name
- NCT04188210
- Testing
- Presence of elbow pain in patients with end stage renal disease
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Namik Kemal University
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
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