Clinical trials: Musculoskeletal Complication
Chronic Kidney Disease (Stage 3-4), Chronic Kidney Disease Mineral and Bone Disorder
Phosphate Assessment in Chronic Kidney Disease Patients Study
The proposed pilot feeding study aims to explore novel pathways in phosphate metabolism and identify new biomarkers, as well as to develop a compound index for assessing phosphate overload with high validity and reliability.
- Trial name
- PACK (NCT07368946)
- Testing
- Dietary Phosphorus Intake
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Arthropathy of Knee, Arthropathy of Hip
Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery
The purpose of this research study is to evaluate effects of respiratory strengthening exercises on breathing function, in people who have orthopedic surgery.
- Conditions
- Arthropathy of Knee, Arthropathy of Hip, Lower Extremity Fracture, Orthopedic Disorder
- Trial name
- NCT05381818
- Testing
- Daily Inspiratory Muscle Training (dIMT), Acute Inspiratory Muscle Training (aIMT), Standard of Care (SOC)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Florida
Bone Diseases, Metabolic Syndrome X
Effect of Exercise and Phytoestrogen on Bone, Metabolic Syndrome Criteria and Complaints of the Early Menopause
The aim of the study is to compare the effect of a progressive, periodized exercise training designed to impact bone, CHD-risk-factors and menopausal complaints versus the combined effect of exercise and "phytoestrogen"…
- Conditions
- Bone Diseases, Metabolic Syndrome X, Coronary Disease
- Trial name
- NCT00663104
- Testing
- exercise, exercise + cimicifuga racemosa
- Where
- Germany
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Arthroplasty, Replacement, Knee, Pain, Postoperative
GENIVS Block Versus Adductor Canal Block After Total Knee Arthroplasty
The goal of this clinical trial is to learn whether the ultrasound-guided GENIVS block is not worse than (non-inferior to) the adductor canal block in reducing opioid use after total knee arthroplasty performed under spinal…
- Conditions
- Arthroplasty, Replacement, Knee, Pain, Postoperative, Osteoarthritis, Knee
- Trial name
- GENIVS-ACB (NCT07901348)
- Testing
- GENIVS block, Adductor Canal Block (ACB) Only
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Hip Osteoarthritis
Fascia Iliaca Block for Postoperative Pain Control After Elective Hip Arthroplasty
This clinical trial aims to assess the analgesic efficacy of ultrasound-guided FIB using different analgesic combinations administered into the iliac fascia compartment.
- Trial name
- FIB-PAIN (NCT06534697)
- Testing
- Naropin, 0.2% Injectable Solution in Sodium chloride, Naropin, 0.2% Injectable Solution in dextrose 5%, Dextrose 10 % in Water
- Volunteers
- 210 people
- Sponsor
- Foisor Orthopedics Clinical Hospital
Pelvic Girdle Pain, Pubic Symphysis Diastasis
Pelvic Girdle Pain Early Postpartum: Underlying Condition and Associated Factors
Background: Pregnancy-related pelvic girdle pain (PGP) can appear during pregnancy, directly after labour or can be delayed to 3 weeks postpartum.
- Conditions
- Pelvic Girdle Pain, Pubic Symphysis Diastasis, Diastasis Recti
- Trial name
- NCT03835650
- Where
- Poland
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Żelazna Medical Centre, LLC
Healthy Volunteers, Musculoskeletal Complication
Use of Specially Designed Pediatric MR Coils on Clinical Scanners
The purpose of this research study is to test the use of new Magnetic Resonance Imaging (MRI) coils. An MRI takes pictures of body parts using a large magnet and a computer.
- Trial name
- NCT01795989
- Testing
- 1.5T MRI Elbow Coil
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Post Mastectomy Complications
Post Mastectomy Shoulder Problems and Kinesio Taping
Applications of new treatment modality which is Kinesio tape in post mastectomy shoulder problems.
- Trial name
- NCT02749539
- Testing
- Kinesio tape, physiotherapy program
- Volunteers
- 70 people
- Sponsor
- Cairo University
Rheumatoid Arthritis, Chronic Kidney Diseases
Physical Activity and Cardiovascular Risk
Physical activity (PA) is essential for the prevention and treatment of chronic conditions. Despite its benefits, global physical inactivity is prevalent, contributing to chronic diseases and premature mortality.
- Conditions
- Rheumatoid Arthritis, Chronic Kidney Diseases, Endothelial Dysfunction, Arterial Stiffness
- Trial name
- PACaR (NCT06440369)
- Testing
- Training group, Physical activity orientation group
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Franche-Comté
Bunions, Postoperative Pain
Dose-Escalation Study of HTX-034 Following Bunionectomy
This was a Phase 1b/2, randomized, blinded, active-controlled study. Phase 1b evaluated escalating doses of HTX-034 compared with bupivacaine HCl.
- Trial name
- NCT04398329
- Testing
- HTX-034 low dose, HTX-034 high dose, Luer lock applicator
- Where
- 4 sites in United States
- Volunteers
- 78 people
- Sponsor
- Heron Therapeutics
NEC, Gastroschisis
Neokare Safety and Tolerability Assessment in Neonates With GI Problems
With an increasing body of evidence to support a causal link between drinking milk that contain cow's milk protein (CMP) and the development of gastrointestinal disturbance in infants, many clinicians avoid the use of CMP…
- Conditions
- NEC, Gastroschisis, Intestinal Perforation, Atresia, Intestinal
- Trial name
- NCT05293353
- Testing
- NeoKare Breast Milk Fortifier
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Implant Complication, Bone Resorption
Standard Implants With Bone Regeneration vs Short Implants
A study designed as a randomized controlled trial of parallel group design will be conducted at the Dental clinic of the University of Valencia to compare, considering different parameters, the rehabilitation with dental implants…
- Trial name
- NCT03524885
- Testing
- Short implant placement, Bone regeneration with longer implants
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Familial Hypophosphatemic Rickets
Calcimimetics in Hypophosphatemic Rickets
Currently, large oral doses of phosphate and 1,25(OH)2D (calcitriol) are the standard treatment of patients with familial hypophosphatemic rickets (XLH).
- Trial name
- CHR (NCT00844740)
- Testing
- Cinacalcet
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Acute Kidney Injury
Acute Kidney Injury in Severe Trauma
Acute kidney injury (AKI) represents a serious complication following severe injury associated with adverse outcome. Main goals of the presented study were to define the incidence of AKI and to evaluate the validity of AKI…
- Trial name
- NCT03433079
- Testing
- Neutrophil gelatinase-associated lipocalin (NGAL), Arterial lactate, Interleukin-6 (IL-6)
- Where
- Czechia
- Volunteers
- 81 people
- Sponsor
- University Hospital Ostrava
Bariatric Surgery Candidate, Muscle Weakness
Inspiratory Muscle Training and Pulmonary Function in Patients Submitted to Bariatric Surgery
Obesity is defined as a body mass index greater than or equal to 30 kg / m2 and represents a public health problem that affects the world population.
- Conditions
- Bariatric Surgery Candidate, Muscle Weakness, Complication,Postoperative, Respiratory Muscle
- Trial name
- NCT05575089
- Testing
- Inspiratory muscle training - Powerbreath, Aerobic exercise in cycle ergometer, Deep breathing exercises
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Universidade Cidade de Sao Paulo
Acute Myeloid Leukemia, Brain Glioblastoma
Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer
This randomized pilot clinical trial studies health care coach support in reducing acute care use and cost in patients with cancer.
- Conditions
- Acute Myeloid Leukemia, Brain Glioblastoma, Estrogen Receptor Negative, Extensive Stage Small Cell Lung Carcinoma
- Trial name
- NCT03154190
- Testing
- Best Practice, Laboratory Biomarker Analysis, Supportive Care
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Stanford University
Acute Leukemia, Adenomatous Polyposis
Familial Investigations of Childhood Cancer Predisposition
NOTE: This is a research study and is not meant to be a substitute for clinical genetic testing. Families may never receive results from the study or may receive results many years from the time they enroll.
- Conditions
- Acute Leukemia, Adenomatous Polyposis, Adrenocortical Carcinoma, AML
- Trial name
- SJFAMILY (NCT03050268)
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- St. Jude Children's Research Hospital
Acute Kidney Injury, Rhabdomyolysis
Myoglobin Removal With CytoSorb in Rhabdomyolysis
The aim of this observational study is to assess whether myoglobin removal with CytoSorb® ameliorates endothelial damage in severe rhabdomyolysis patients who are admitted to the intensive care unit.
- Conditions
- Acute Kidney Injury, Rhabdomyolysis, Endothelial Dysfunction
- Trial name
- NCT06503289
- Testing
- Cytosorb therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Scoliosis
Sensorial and Physiological Mechanism-based Assessments of Perioperative Pain
The overall goal of this proposal is to determine if quantitative sensory testing (QST) assessing pain modulation can be used as a clinical tool to optimize perioperative pain management.
- Trial name
- RCT (NCT03537612)
- Testing
- Clonidine, Morphine
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Dr. Jean A. Ouellet, MD, FRCSC
Erector Spinae Plane Block, Wound Infiltration
Postoperative Pain in Lumbar Disc Surgery
This study included 46 patients who underwent lumbar disc herniation surgery under general anesthesia. After the operation, US-guided ESPB was performed on Group E, and WI was performed on Group W.
- Conditions
- Erector Spinae Plane Block, Wound Infiltration, Lumbar Disc Herniation, Postoperative Pain
- Trial name
- Pain (NCT06844747)
- Testing
- erector spinae plane block(ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
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