Clinical trials: Musculoskeletal Complication
Insulin Resistance, Postoperative Complication
Evaluation of Preoperative Oral Rehydration Solution in Colectomy
Elective colectomy procedures typically require bowel preparation starting 2 days prior to the surgery. Osmotic laxatives such as Colyte® are administered 2 days prior, and Nothing by mouth (NPO) is required 1 day prior to ensure…
- Trial name
- NCT02062788
- Testing
- Oral rehydration solution
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Seoul National University Hospital
Hypertension, Depression
Patient-Centred Innovations for Persons With Multimorbidity - Ontario
The aim of Patient-Centred Innovations for Persons With Multimorbidity (PACE in MM) study is to reorient the health care system from a single disease focus to a multimorbidity focus; centre on not only disease but also the…
- Conditions
- Hypertension, Depression, Anxiety, Musculoskeletal Pain
- Trial name
- PACEinMM-ON (NCT02742597)
- Testing
- TIP / IMPACT Plus Care Coordination
- Where
- 9 sites in Canada
- Volunteers
- 175 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Kidney Disease-Mineral and Bone Disorder
To Investigate the Bone and Muscle Abnormalities in Patients With Chronic Kidney Disease With MRI
Patients with chronic kidney disease (CKD) have a higher risk of fractures than those without. The purpose of this study is to develop a non-invasive Magnetic resonance imaging (MRI) method that can improve fracture risk…
- Trial name
- NCT04564924
- Testing
- DXA
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Rheumatoid Arthritis
Anti-TNFα Use During Elective Foot and Ankle Surgery in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a frequent inflammatory arthritis that can lead to severe joint deformity and often requires orthopaedic surgical interventions.
- Trial name
- NCT02242474
- Testing
- Anti-TNF suspended perioperatively, Anti-TNFα continued perioperatively
- Where
- Canada
- Volunteers
- 660 people
- Sponsor
- CHU de Quebec-Universite Laval
Scoliosis, Pain
Perioperative Methadone Use to Decrease Opioid Requirement in Pediatric Spinal Fusion Patients
Acute pain management following major surgical procedures in pediatric patients continues to be a challenge, especially after extensive posterior spine fusions.
- Trial name
- NCT02558010
- Testing
- Methadone, Normal Saline, Morphine
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Medical College of Wisconsin
Hip Osteoarthritis
Minimal Invasive Surgery in Total Hip Arthroplasty Patients; Strength, Functionality and Post Operative Complications
The aim of the present study is to explore the most efficient surgical approach in total hip replacement in short and long term when concerning strength, functionality and postoperative complications.
- Trial name
- NCT01959360
- Testing
- Direct lateral, minimal invasive, modified minimal invasive
- Where
- Norway
- Volunteers
- 59 people
- Sponsor
- Norwegian University of Science and Technology
SGA, Turner Syndrome, Noonan Syndrome, ISS
A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow
The study compares two medicines for treatment of children born small and who stay small, or with Turner Syndrome, Noonan Syndrome, or idiopathic short stature.
- Trial name
- REAL 8 (NCT05330325)
- Testing
- Somapacitan, Norditropin®
- Where
- 199 sites in United States, Austria and 31 more
- Volunteers
- 412 people
- Sponsor
- Novo Nordisk A/S
Shoulder Pain, Postoperative Pain
Suprascapular Nerve Block Efficacy for Shoulder Surgery
This study evaluates the analgesia induced by suprascapular nerve block in comparison to interscalene nerve block in arthroscopic rotator cuff repairs.
- Conditions
- Shoulder Pain, Postoperative Pain, Rotator Cuff Tears, Anesthesia
- Trial name
- NCT04364542
- Testing
- Suprascapular nerve block, Interscalene Nerve Block, Arthroscopic rotator cuff repair
- Where
- Brazil
- Volunteers
- 98 people
- Sponsor
- Ivan Simionato
Pain, Shoulder
Continuous Interscalene Block for Same Day Discharge Following Total Shoulder Arthroplasty
Total shoulder surgeries are associated with considerable postoperative pain which may prevent rehabilitation and early discharge from the hospital.
- Trial name
- NCT01785940
- Testing
- Interscalene block
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Diabetes Complications
Effectiveness of Shock Wave Therapy Versus Low Level Lazer Therapy in Diabetic Frozen Shoulder Patients.
Patients will be divided randomly into 3 groups.
- Trial name
- NCT05967923
- Testing
- Shock wave therapy, Low level lazer therapy, Routine physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- South Valley University
Pierre Robin Syndrome, Cleft Palate
Postoperative Complications After Cleft Palate Closure in Patients With Pierre Robin Sequence: Operative Considerations
In cleft surgery there is no current general agreement on the treatment strategy of patients with the Pierre Robin Sequence. The timing of surgery and the surgical approach depends on the treating physician or the hospital…
- Trial name
- NCT02658318
- Where
- Belgium
- Volunteers
- 92 people
- Sponsor
- AZ Sint-Jan AV
Autosomal Dominant Hypocalcemia (ADH)
Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1
The primary purpose of the study is to understand the effectiveness, safety, and tolerability of encaleret when compared to standard of care (SoC) treatment in participants with Autosomal Dominant Hypocalcemia Type 1 (ADH1).
- Trial name
- CALIBRATE (NCT05680818)
- Testing
- Encaleret, Standard of Care
- Where
- 25 sites in United States, Australia and 8 more
- Volunteers
- 67 people
- Sponsor
- Calcilytix Therapeutics, Inc., a BridgeBio company
Respiration, Artificial, Critical Care
Weaning Algorithm for Mechanical VEntilation
To compare the duration of mechanical ventilation and the weaning period between two groups of patients managed with either Standard Care or with mechanical ventilation adjusted according to the Beacon Caresystem, in patients…
- Conditions
- Respiration, Artificial, Critical Care, Respiratory Insufficiency, Intensive Care (ICU) Myopathy
- Trial name
- WAVE (NCT03697785)
- Testing
- Beacon Care System
- Where
- 2 sites in United Kingdom
- Volunteers
- 286 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Pain, Postoperative, Osteoarthritis, Knee / Osteoarthritis, Hip
iPACK Block vs. Periarticular Infiltration for TKA Pain Control
This study aims to retrospectively compare two different multimodal analgesic techniques for pain management after total knee arthroplasty (TKA).
- Trial name
- NCT07267650
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Turgutlu State Hospital
Hyperphosphatemia
The Effect of Oral Niacinamide on Plasma Phosphorus Levels in Peritoneal Dialysis Patients
Hyperphosphatemia is common in the peritoneal dialysis population. Current strategies are insufficient to optimize phosphorus control.
- Trial name
- NCT00508885
- Testing
- Niacinamide
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Washington University School of Medicine
Knee Osteoarthritis
Effect of Foot Massage on Pain and Analgesic Consumption in Total Knee Prosthesis
This randomized controlled trial aims to examine the effects of foot massage combined with cold application on postoperative pain, patient satisfaction, and analgesic consumption in individuals undergoing Total Knee Arthroplasty…
- Trial name
- NCT07126340
- Testing
- Foot Massage and Cold Application, Cold Application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alev Keskin
Complications After Gastric Bypass Operation
Complications After Bariatric Surgery - a Clinical Trial
The number of obese is increasing rapidly. Bariatric surgery is used to a greater and greater extent as treatment of obesity to obtain a greater and more permanent weight loss.
- Trial name
- NCT01930838
- Testing
- Gastric bypass operation
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Aarhus
Blood Loss, Surgical, Scoliosis
Local Subfascial and Intramuscular Tranexamic Acid Administration in Pediatric Patient Undergoing Scoliosis Surgery, Double Blind Randomized Control Trial
We hypothesized that local administration of tranexamic acid will minimize blood loss and blood product administration in pediatric patient undergoing scoliosis surgery
- Trial name
- NCT04622397
- Testing
- Tranexamic acid injection, Saline
- Volunteers
- 30 people
- Sponsor
- Cairo University
Ovarian Tumor
Assess Cancer in Ovarian Tumors With Biomarkers.
Purpose The OvaRI assay clinical trial is directed at evaluating a novel proteomics-based blood test. This test is for a physician to use towards differentiating benign from malignant ovarian tumors prior to surgical…
- Trial name
- NCT00436189
- Testing
- Blood Draw
- Where
- 18 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Ciphergen Biosystems
Arthrodesis, Degenerative Arthritis
INBONE Total Ankle Arthroplasty(TAA)Using Calcaneal Stem Fixation
The primary objective of this study is to evaluate the radiographic outcomes of Total Ankle Arthroplasty in patients having a calcaneal stem.
- Conditions
- Arthrodesis, Degenerative Arthritis, Rheumatoid Arthritis, Complications; Arthroplasty, Mechanical
- Trial name
- NCT01366989
- Testing
- Radiographic evaluation of previously implanted patients
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stryker Trauma and Extremities
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