Clinical trials: Musculoskeletal Disorders, open to volunteers
Mucopolysaccharidoses, Progressive Pseudorheumatoid Dysplasia
Pediatric Arthropathy Beyond Inflammation: Clinical Spectrum and Diagnostic Approach at Assiut University Children Hospital
To identify the most common underlying causes of non-inflammatory arthropathy in children presenting to Assiut University Children Hospital for through clinical evaluation, laboratory testing, and imaging, in order to improve…
- Conditions
- Mucopolysaccharidoses, Progressive Pseudorheumatoid Dysplasia, Farber Disease, Osteogenesis Imperfecta
- Trial name
- NCT07173010
- Volunteers
- 35 people
- Sponsor
- Assiut University
Fibromyalgia
Manual Diaphragmatic Release on Exercise Capacity and Quality of Life in Women With Fibromyalgia
Evaluate the effect of manual diaphragmatic release on exercise capacity, inspiratory muscles strength, symptoms severity, and health-related quality of life in women diagnosed with fibromyalgia.
- Trial name
- NCT07641166
- Testing
- Manual Diaphragmatic Release, Aerobic Training
- Volunteers
- 60 people
- Sponsor
- Middle East University
Tooth Loss, Alveolar Bone Loss
Immediate Molar Implants With Customized Healing Abutments in Different Post-Extraction Socket Classes
Immediate implant placement into a fresh extraction socket shortens overall treatment time and reduces the number of surgical procedures, but the fit between the implant and the socket walls, and the resulting soft-tissue…
- Conditions
- Tooth Loss, Alveolar Bone Loss, Jaw, Edentulous, Partially
- Trial name
- IMPLA-CHA (NCT07801573)
- Testing
- Immediate implant placement with customized healing abutment
- Where
- Bulgaria
- Volunteers
- 60 people
- Sponsor
- Plovdiv Medical University
Shoulder Disease, Shoulder Impingement
Cross-sectorial Use of Patient-Reported Outcomes in Chronic Degenerative Shoulder Conditions
This research project aims to test if systematic (extensive) use of patient-reported outcomes across treatment boundaries can 1.
- Conditions
- Shoulder Disease, Shoulder Impingement, Shoulder Osteoarthritis, Shoulder Frozen
- Trial name
- C-PRO (NCT06435494)
- Testing
- Systematic use of patient reported outcome measures in clinical work with the patients
- Where
- 6 sites in Denmark
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Rotator Cuff Syndrome, Shoulder Instability
Virtual Reality Intervention in Patients With Persistent Shoulder Pain
Shoulder pain is very common and can make daily activities difficult. Many people have shoulder pain for a long time, even after treatment.
- Conditions
- Rotator Cuff Syndrome, Shoulder Instability, Frozen Shoulder
- Trial name
- NCT07390227
- Testing
- Exercise with Virtual reality, education on shoulder pain, simulation de-briefing
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- HAN University of Applied Sciences
Psoriatic Arthritis, Ultrasound Assessment
Apremilast and Adalimumab in Psoriatic Arthritis Patients
The aim of this work is to compare the efficacy of Apremilast combined with Methotrexate versus Adalimumab combined with Methotrexate
- Conditions
- Psoriatic Arthritis, Ultrasound Assessment, TNF
- Trial name
- NCT07398651
- Testing
- Adalimumab, Apremilast
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Osteogenesis Imperfecta
Audio-vestibular Evaluation of Children and Young Adults With Osteogenesis Imperfecta
The aim is to determine whether vestibular deficits are present in OI, then to establish whether a correlation exists between genetic type, severity of OI and audiovestibular phenotype.
- Trial name
- AVOI (NCT05419960)
- Testing
- Vestibular Assessment, Petrous bone Computed Tomography (CT), Magnetic Resonance Imaging (MRI)
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Shoulder Adhesive Capsulitis
Feasibility, Usability and Preliminary Efficacy of Home-based FES Fro Adhesive Capsulitis
The purpose of this study is to investigate the feasibility, usability and preliminary efficacy of a home-based Functional Electrical Stimulation(FES) in individuals with shoulder adhesive capsulitis.
- Trial name
- NCT07227662
- Testing
- Home based FES in combination with usual therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Maryland, Baltimore
Hip Dysplasia, Hypermobility Syndrome
Dynamic Lycra Garments for Hip Dysplasia Feasibility Study
Dynamic lycra garments are deployed in rehabilitation and exercise to support unstable areas of the body, enhance sensory feedback to improve movement patterns, reduce fatigue and pain and improve function.
- Trial name
- HIPlycra (NCT07438873)
- Testing
- Lycra Shorts
- Volunteers
- 12 people
- Sponsor
- Royal National Orthopaedic Hospital NHS Trust
Education, Joint Diseases
The Application of Artificial Intelligence in Wrist and Hand Joint Ultrasound
1. To develop an AI system that can automatically identify standard sections and save images during wrist and hand joint ultrasound scans, while labeling key anatomical structures. 2.
- Trial name
- NCT06883669
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Flat Feet, Flexor Tendon Rupture
Medial Displacement Calcaneal Osteotomy and FDL- Transfer - With a Human, Allogeneic Cortical Bone Screw
The goal of this observational study is to compare the use of a screw made of human bone (Shark-Screw®, Surgebright-GmbH) with the metal/Bio-Tenodesis screw (Arthrex) in the treatment of the symptomatic flatfoot using the…
- Conditions
- Flat Feet, Flexor Tendon Rupture, Tibialis Posterior Dysfunction, Deformity, Foot
- Trial name
- NCT05643079
- Testing
- medializing calcaneal osteotomy and/or transfer of the flexor digitorum longus tendon (FDL) with metal/Bio-Tenodesis screws, medializing calcaneal osteotomy and/or transfer of the flexor digitorum longus tendon (FDL) with Shark Screws®
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Orthopedic Hospital Vienna Speising
Anterior Knee Pain
Effects of Training Frequency on Patellofemoral Pain Rehabilitation.
This clinical trial aims to determine the optimal frequency of exercise therapy for improving pain, function, and quality of life in participants with patellofemoral pain.
- Trial name
- ETFRPPRRCT (NCT06808386)
- Testing
- Strengthening 2 times per week, Strengthening 3 times per week
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- University of Nove de Julho
Patellofemoral Pain Syndrome
Popliteus Muscle Release Versus Kinesio Taping
The aim of the current study is to compare the effect of popliteus muscle release and Kinesio taping on pain intensity, function, dynamic balance, and quadriceps muscle strength in patients with patellofemoral pain syndrome.
- Trial name
- NCT07290296
- Testing
- Traditional Physical Therapy Treatment, Popliteus Muscle Release, Kinesio Taping
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Back Pain, Low Back Pain
Low Back and Neck Pain in Nursing Students at The University of The West Indies
The purpose of this study is to identify the prevalence of neck and low back pain in nursing students enrolled at the University of the West Indies, Mona; to assess their knowledge, attitude and practice of good spine health and…
- Conditions
- Back Pain, Low Back Pain, Musculoskeletal Pain, Neck Pain
- Trial name
- NCT07167888
- Testing
- Clinical Control Group (Group A), Spine Exercise Program (Group B)
- Where
- Jamaica
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Hip Osteoarthritis
MOVE-HIP: Ceramic Hip Resurfacing Versus Total Hip Arthroplasty Using Activity Monitoring
MOVE-HIP is a pragmatic, multicenter randomized clinical trial comparing ceramic hip resurfacing arthroplasty with contemporary total hip arthroplasty in adults with symptomatic hip osteoarthritis who are considered clinically…
- Trial name
- MOVE-HIP (NCT07839403)
- Testing
- Ceramic-on-Ceramic Hip Resurfacing Arthroplasty, Contemporary Total Hip Arthroplasty
- Where
- Sweden
- Volunteers
- 220 people
- Sponsor
- Danderyd Hospital
Knee Osteoarthritis
MultiCenter IDE Study of the PEEK-OPTIMA™ Femoral Component vs a CoCr Alloy TKA Femoral Component of Similar Design
The purpose of this investigational device exemption (IDE) study is to monitor the performance (safety and efficacy) of the Maxx Orthopedics, Freedom Total Knee® System, with a femoral component of similar design, manufactured…
- Trial name
- NCT06627673
- Testing
- Total Knee Arthroplasty
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Maxx Orthopedics Inc
Hemiparesis, Paraparesis
Immediate Effects On Gait and Spasticity After The Use Of Passive Kinesiotherapy Equipment In The Lower Limbs Of Neurological Patients
Undergo assessment of muscle tone (Ashworth Scale), gait (BAIOBIT) and risk of falling (Timed Up and Go) before using the device; Use the device on the spastic lower limb(s) for 30 minutes; Go through the same assessment carried…
- Conditions
- Hemiparesis, Paraparesis, Tetraparesis, Cerebral Palsy
- Trial name
- NCT06696040
- Testing
- Passive mobilization using a device
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Fernanda Trubian
Centronuclear Myopathy
Multispectral Optoacoustic Tomography for Advanced Imaging of Centronuclear Myopathy
Twenty patients with centronuclear myopathy and twenty age- and sex-matched, muscle-healthy controls will undergo diagnostic examination.
- Trial name
- MOSAIC (NCT07021820)
- Testing
- MSOT
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Subacromial Impingement Syndrome
Effects of Different Kinesio Taping Methods in Subacromial Impingement Syndrome
This prospective, randomized controlled trial aims to compare the effects of two different kinesio taping techniques on pain, shoulder function, acromiohumeral distance, and shoulder proprioception in patients with subacromial…
- Trial name
- NCT07891481
- Testing
- Conventional Kinesio Taping, Scapular Kinesio Taping, Therapeutic Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Pamukkale University
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Impact of Muscle Degeneration in Chronic Low Back Pain
Surgical interventions for the removal of intervertebral disc fragments or to enlarge a narrow spine canal are commonly performed worldwide and are considered efficient.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Radiculopathy, Back Pain
- Trial name
- NCT04273828
- Testing
- Lumbar decompressive surgery
- Where
- Brazil
- Volunteers
- 168 people
- Sponsor
- Hospital Israelita Albert Einstein