Clinical trials: Musculoskeletal Injuries
Knee Injuries, Knee Arthritis
Kinematic Parameters to Predict Knee Diseases.
There is no study to explore the prediction of knee diseases using kinematic parameters of knee during gait. The aim of this study is to explore the possibility of predicting knee diseases by gait parameters.
- Trial name
- NCT03130400
- Testing
- Observational gait analysis procedure
- Where
- China
- Volunteers
- 1,914 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Achilles Tendinitis, Tendinopathy
Clinical Trial to Evaluate the Adjuvant Effect of Shock Wave Therapy in the Insertional Achilles Tendinopathy
Background: There is no consensus regarding the treatment of insertional tendinopathies. The good results of the eccentric training in the management of the non-insertional Achilles tendinopathy were not reproducible in the…
- Trial name
- NCT02757664
- Testing
- Shock Wave Therapy, Eccentric Exercises
- Where
- Brazil
- Volunteers
- 119 people
- Sponsor
- Federal University of São Paulo
Shoulder Pain, Shoulder Injuries
Efficacy of a Criteria Based Clinical Pathway for Rehabilitation of Shoulder Injuries
The goal of this clinical trial is to compare the current standard of care for rehabilitation of non-operative shoulder injuries to a novel, criteria-based approach (CRISP).
- Trial name
- CRISP (NCT06536114)
- Testing
- CRISP: Criteria-Based Approach for the Rehabilitation for Non-Operative Shoulder Injuries, Standard of Care
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- United States Naval Medical Center, San Diego
Tendinopathy
Efficacy of Therapeutic Percutaneous Electrolysis Simple vs Multiple vs Laser Therapy in Supraspinatus Tendinopathy.
Supraspinatus tendinopathy is one of the main pathologies that cause functional alterations in the glenohumeral joint. It reduces the quality of life of the population suffering from this injury.
- Trial name
- NCT07695792
- Testing
- Simple electrolysis percutaneous, Multifiliar Electrolysis percutaneus, Laser
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad Pontificia de Salamanca
Musculoskeletal Diseases, Musculoskeletal Injury
Prevalence of Musculoskeletal Symptoms in the Cambridge NIHR BioResource
Musculoskeletal diseases, such as osteoarthritis, represent a large proportion of the global burden of disease with hip and knee osteoarthritis alone being the 11th greatest cause of disease burden.
- Trial name
- NCT04632563
- Testing
- Questionnaire including MSK-HQ (Musculoskeletal Health Questionnaire)
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Cancers, Cardiovascular Diseases
Cohort of Swedish Men
The Cohort of Swedish Men began in 1997, when all men born between 1918 and 1952 and residing in two counties in central Sweden received a questionnaire including about 350 items concerning diet and other lifestyle factors.
- Conditions
- Cancers, Cardiovascular Diseases, Cataract, Gastrointestinal Diseases
- Trial name
- COSM (NCT01127711)
- Volunteers
- 48,850 people
- Sponsor
- Karolinska Institutet
Arthritis, Osteoarthritis
The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study
Adolescents and young adults who hurt their knees playing sports or doing recreational activities can develop joint damage, muscle weakness, inactivity, and weight gain which might lead to an increased risk of osteoarthritis…
- Conditions
- Arthritis, Osteoarthritis, Arthritis Knee, Osteo Arthritis Knee
- Trial name
- SOARPOC (NCT04956393)
- Testing
- Immediate 8-Week SOAR Program, Delayed 8-Week SOAR Program
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Shoulder Impingement
Therapeutic Approaches for Subjects With Scapula Dyskinesis
The investigators will test whether conscious control with manual guides and video or EMG biofeedback will enhance 3-D kinematics of scapula in shoulder dysfunction subjects with different type of scapula dyskinesis.
- Trial name
- NCT03252444
- Testing
- Conscious control, Conscious control+biofeedback
- Where
- Taiwan
- Volunteers
- 139 people
- Sponsor
- National Taiwan University Hospital
Plantar Fascitis
Low-Level Laser Therapy for Plantar Fasciitis
Plantar fasciitis (PF), a degenerative injury of the connective tissue in the foot, results in pain-related disability in Service Members and contributes to decreased physical activity and excessive healthcare costs.
- Trial name
- NCT05763381
- Testing
- Photobiomodulation Therapy (PBMT)
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- The Geneva Foundation
Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ), Oxygen
Topical Oxygen Therapy for BRONJ
A randomized clinical trial comparing Blue®m oral gel and autologous PRF membrane as adjuncts to surgical debridement in BRONJ/MRONJ patients.
- Conditions
- Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ), Oxygen, Topical Administration, Wound Healing
- Trial name
- OXY-BRONJ Tria (NCT07725107)
- Testing
- Topical Blue®m application, PRF membrane placement
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Mansoura University
Distal Radius Fracture, Osteoporosis
Utility of Cortical Bone Tissue Properties in the Assessment of Fracture Risk
The objective of this study is to determine whether a new minimally invasive method for in vivo measurement of cortical bone tissue properties can identify those who are at risk for fragility fractures of the hip and radius.
- Conditions
- Distal Radius Fracture, Osteoporosis, Hip Fractures
- Trial name
- NCT03076034
- Testing
- Reference Point Indentation
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Fracture, Dislocation
Ketamine-propofol Versus Ketamine Alone for Procedural Sedation in Adults
Using Ketamine for procedural sedation in adults is often uncomfortable for emergency physicians because of the significant proportion of patients experimenting recovery agitation.
- Trial name
- NCT01544725
- Testing
- Procedural sedation with ketamine-propofol combination, Procedural sedation with ketamine alone
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Lateral Epicondylitis, Lateral Elbow Tendinopathy (Tennis Elbow)
Ultrasonographic Examination of Other Enthesitis Sites in Patients With Lateral Epicondylitis
Lateral epicondylitis (LE) is the tendinopathy of the common extensor tendon. Although exact etiology remains unclear, it is believed to be caused by overuse.
- Trial name
- NCT07314840
- Testing
- Madrid Sonographic Enthesitis Index
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Cerebral Palsy, Muscular Dystrophy
Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders
Background: People with cerebral palsy, spina bifida, muscular dystrophy, or spinal cord injury often have muscle weakness and problems controlling how their legs move. This can affect how they walk.
- Conditions
- Cerebral Palsy, Muscular Dystrophy, Spina Bifida, Incomplete Spinal Cord Injury
- Trial name
- NCT05726591
- Testing
- EA-KAFO
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Tennis Elbow
Comparative Effects of Shockwave Therapy and Eccentric Exercises in Patients With Lateral Epicondylitis
The goal of this randomized controlled trial is to compare the effects of shockwave therapy and eccentric exercises on pain, functional ability, quality of life, grip strength and range of motion in patients with lateral…
- Trial name
- NCT07523893
- Testing
- Shockwave Therapy, Eccentric exercises
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Ibadat International University, Islamabad
Knee Osteoarthritis, Arthritis
Inflammatory Response Conventional Total Knee Replacement Versus Mako Total Knee Replacement
Total knee Arthroplasty (TKA) is a highly effective treatment for knee osteoarthritis. Mid- to long-term follow-up studies have shown good clinical outcomes following TKA; despite these results, there is a high incidence of…
- Conditions
- Knee Osteoarthritis, Arthritis, Surgery
- Trial name
- NCT04192006
- Testing
- Total Knee Arthroplasty
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University College, London
Pain
Platelet-rich-plasma Treating Tennis Elbow
The study is to compare the efficacy of autologous platelet concentrate injections to corticosteroid injection in patients suffering from tennis elbow with respect to pain and function.
- Trial name
- NCT00757289
- Testing
- PRP Injection, Corticosteroid Injection
- Where
- Netherlands
- Volunteers
- 106 people
- Sponsor
- Zimmer Biomet
Chronic Musculoskeletal Pain, Posttraumatic Stress Disorder (PTSD)
Neurobiological and Psychological Benefits of Exercise in Chronic Pain and PTSD
The wars in Iraq and Afghanistan are creating a new generation of Veterans, including an increasing number of women Veterans, who present with comorbid PTSD and chronic pain conditions from recent deployment-related physical…
- Conditions
- Chronic Musculoskeletal Pain, Posttraumatic Stress Disorder (PTSD), Mild or Moderate Traumatic Brain Injury
- Trial name
- EXCPPTSD (NCT03283163)
- Testing
- Exercise Testing and Training
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Primary Osteoarthritis, Secondary Osteoarthritis
Clinical and Radiological Outcomes of Medacta Shoulder System
This is a post-marketing surveillance on Medacta Shoulder System
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Rotator Cuff Tear Arthropathy, Rheumatoid Arthritis Shoulder
- Trial name
- NCT03547947
- Testing
- Medacta Shoulder System
- Where
- 6 sites in France, Germany and 1 more
- Volunteers
- 200 people
- Sponsor
- Medacta International SA
Pubic Symphysis Diastasis
Percutaneous TightRope Fixation for Traumatic Pubic Symphysis Diastasis
This study is done to evaluate the safety of a minimal anterior approach to the pubis symphysis and to examine the efficacy of TightRope for internal fixation of pubic symphysis traumatic diastasis.
- Trial name
- NCT05763784
- Testing
- Tightrope
- Sponsor
- University of Texas Southwestern Medical Center
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