Clinical trials: Musculoskeletal Injuries
Degenerative Disc Disease, Kyphosis
Post-Market Clinical Follow-up Study of A-SPINE's Products
This is a post-market clinical follow-up study that use questionnaires such as Visual Analog Scale (VAS), the Neck Disability Index (NDI), or the Oswestry Disability Index (ODI) to compare the clinical improvement effects before…
- Conditions
- Degenerative Disc Disease, Kyphosis, Scoliosis, Trauma
- Trial name
- NCT04848376
- Testing
- (1) SmartLoc (2) SmartLoc Evo (3) Winloc(4) Vigor PEEK Cervical Disc Spacer (5) Combo C (6) Polymer Lumbar Disc Spacer (7) X'Plo (8) Rainboo (9) Combo L
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- A-Spine Asia Co., Ltd.
Acute Respiratory Distress Syndrome ARDS
Driving Pressure-guided Tidal Volume Ventilation in the Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) is associated with high mortality, some of which can be attributed to ventilator-induced lung injury (VILI) when artificial ventilation is not customized to the severity of lung injury.
- Trial name
- DRIVENT (NCT06322758)
- Testing
- Tidal volume customization in the acute respiratory distress syndrome
- Volunteers
- 750 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteopenia
The Natural History of Injury-Related Disuse Osteopenia
Determine the severity and time course (natural history) of disuse osteopenia that occurs in the lower extremity(ies) and lumbar spine of patients sustaining lower extremity injuries that require the patient to maintain…
- Trial name
- NCT03868085
- Testing
- dual energy x-ray absorptiometry
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Milton S. Hershey Medical Center
Wrist Fractures, Shoulder Pain
Shoulder Proprioceptive Training During Immobilization of the Wrist
The goal of this randomized clinical trial is to compare how a program of proprioceptive exercises for the shoulder could influence in pain, functionality, quality of life and shoulder muscle overload in people that are…
- Trial name
- NCT05943340
- Testing
- Proprioceptive exercises
- Volunteers
- 28 people
- Sponsor
- University of Malaga
Osteoporosis
Does Vibration Therapy Induce Higher Than Normal Bone Strains and Strain Rates Than Those Experienced During Habitual Daily Activities
The overall aim of this study is to test the hypothesis that vibration exercise can induce higher than normal bone strains and strain rates than are experienced during habitual locomotor activities.
- Trial name
- NCT01430858
- Testing
- Strain Gauge, Vibration therapy
- Where
- United Kingdom
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Shoulder Dislocation
The Arthroscopic Treatment of Recurrent Anterior Shoulder Instability
The objective of this study is to investigate arthroscopic treatments of recurrent anterior shoulder instability. Functional outcomes of arthroscopic anatomic glenoid reconstruction with bone graft will be compared to the gold…
- Trial name
- ATRASI (NCT02510625)
- Testing
- Anatomic Glenoid Reconstruction, Arthroscopic bankart Repair
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Shoulder Dislocation, Blood Flow Restriction Training
Intervention of Shoulder Blood Flow Restriction Training on Shoulder Joint Pain and Function of Judo Athletes
To observe the effect of shoulder low load blood flow restriction training on pain, function, strength and joint motion of the subjects with shoulder joint dysfunction.
- Trial name
- whsu (NCT06470789)
- Testing
- Shoulder blood restriction training
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Yang Liu
Subacromial Impingement Syndrome
Ultrasonography Guided Subacromial Sodium Hyaluronate Injection in Rotator Cuff Disease
This study will be performed to examine the effect of ultrasound-guided subacromial sodium hyaluronate injection in patients with impingement syndrome without rotator cuff complete tear.
- Trial name
- NCT01735058
- Testing
- Sodium Hyaluronate, Normal saline
- Where
- Iran
- Volunteers
- 48 people
- Sponsor
- Isfahan University of Medical Sciences
Osteoarthritis, Hip, Joint Deformities, Acquired
Efficacy of Aquamantys for Reducing Transfusions With Anterior Supine Intermuscular Approach Total Hip Arthroplasty
The purpose of this study is to establish whether or not there is a clinical advantage to the use of Aquamantys® System from Medtronic Advanced Energy (formerly Salient Surgical Technologies) in patients undergoing primary total…
- Conditions
- Osteoarthritis, Hip, Joint Deformities, Acquired, Hip Dislocation, Congenital, Osteonecrosis
- Trial name
- Aquamantys (NCT01583465)
- Testing
- Aquamantys, standard electrocautery (Bovie)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Joint Implant Surgeons, Inc.
Hip Dysplasia, Hip Injuries
PENG Block vs. ESP Block for Pediatric Hip Surgery
The study compares the effectiveness and safety of the pericapsular nerve blockade vs. ESPB in pediatric patients who underwent hip surgeries.
- Conditions
- Hip Dysplasia, Hip Injuries, Hip Fractures, Hip Disease
- Trial name
- NCT06087549
- Testing
- Pericapsular nerve group block using 0.2% ropivacaine, Erector Spinae Plane Block using 0.2% ropivacaine, Standard care
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Orthopedic Disorder
Elbow Outcomes Clinical Study (WELBOW)
WELBOW study is an international, ambispective and prospective, single arm, multicenter, observational, non-comparative, Post-Market Clinical Follow-up (PMCF).
- Trial name
- WELBOW (NCT04173377)
- Where
- 7 sites in Belgium, Canada and 2 more
- Volunteers
- 310 people
- Sponsor
- Stryker Trauma and Extremities
Scoliosis, Acute Kidney Injury
Effects of Goal-directed Fluid Therapy on Post-operative Outcomes in Children Undergoing Scoliosis Repair
Surgery for scoliosis correction, the abnormal curvature of the spine, is a major procedure often undertaken in adolescents. In adult anesthesia, there is a large volume of literature debating how to optimize fluids administered…
- Trial name
- CardioQ-RP (NCT02463175)
- Testing
- Plasmalyte, Goal-directed fluid therapy (GDT)
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of British Columbia
Fasciitis, Plantar
Efficacy of Focused Shock Waves Combined With Adjuvant Therapy With Tendon Supplement
Physical treatment with focused shock waves is effective in the treatment of tendonitis. Food supplements could facilitate the healing of tendinopathies when combined with shock wave therapy.
- Trial name
- NCT04664712
- Testing
- Tendisulfur Pro, Focused shock wave
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Osteoporosis, Diagnoses Disease
Normative Database for HR-pQCT-Based Radius and Tibia Strength
A novel methodology was recently developed and validated by the applicants to compute bone strength at the distal radius and tibia using second-generation HR-pQCT reconstructions.
- Conditions
- Osteoporosis, Diagnoses Disease, Fracture, Bone Strength
- Trial name
- NODARATIS (NCT03219099)
- Where
- Switzerland
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Subacromial Impingement Syndrome
Comparison of Supervised Rehabilitation and Home Exercise Programs in Subacromial Impingement Syndrome
This randomized controlled trial aims to compare the effectiveness of physiotherapist-supervised rehabilitation and home exercise programs in individuals with subacromial impingement syndrome (SAIS).
- Trial name
- SAIS-REHAB (NCT07568340)
- Testing
- Supervised Rehabilitation Program, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Air or Gas Embolism, Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy Registry
The purpose of the Hyperbaric Oxygen Therapy Registry (HBOTR) is to provide real world patient outcome and side effect information from electronic health records submitted to a specialty specific hyperbaric registry as part of…
- Conditions
- Air or Gas Embolism, Carbon Monoxide Poisoning, Clostridial Myositis and Myonecrosis (Gas Gangrene), Crush Injury, Compartment Syndrome & Other Acute Traumatic Ischemias
- Trial name
- HBOTR (NCT02483650)
- Volunteers
- 5,000 people
- Sponsor
- U.S. Wound Registry
Spasticity
A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity.
The purpose of the study is to assess the safety and efficacy of increasing doses of Corabotase (also known as IPN10200) with the aim to evaluate the Pharmacodynamics (PD) profile of Corabotase and to establish the total…
- Trial name
- LANTIMA (NCT04752774)
- Testing
- Corabotase, Dysport
- Where
- 81 sites in United States, Austria and 12 more
- Volunteers
- 240 people
- Sponsor
- Ipsen
Fractures, Osteoporosis
Effectiveness of an Educational Program in the Prevention of Osteoporosis and Fractures
The study will elucidate the effectiveness of an educational program in the prevention of osteoporosis and fractures. A random sample of the female population in Southern Finland (Uusimaa region) within the age group of 60-70…
- Trial name
- NCT00589615
- Testing
- multidisciplinary osteoporosis prevention educational program
- Where
- Finland
- Volunteers
- 2,181 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Fracture, Bone Fracture
AI Assisted Detection of Fractures on X-Rays (FRACT-AI)
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Fracture, Bone Fracture, Dislocation, Fracture Multiple
- Trial name
- FRACT-AI (NCT06130397)
- Testing
- Cases reading, Ground truthing
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Osteoporosis, Age-Related, Humeral Fractures
Teriparatide for Fracture Repair in Humans
This study will test the hypothesis that daily subcuaneous administration of 20µg of teriparatide (TPTD) as compared to daily subcuaneous placebo for twelve weeks accelerates proximal 2-segment humerus fracture healing and…
- Trial name
- TERAFRAP (NCT02091492)
- Testing
- Teriparatide
- Where
- Austria
- Sponsor
- Medical University of Vienna