Clinical trials: Musculoskeletal Injuries
Osteoarthritis Knees Both Post-Traumatic
Preventing Knee Osteoarthritis Through Exercise and Education Following Knee Injury
This study evaluates the preliminary efficacy of an 8-week exercise and education intervention on musculoskeletal health of young adults with a previous sport-related knee injury that are at high risk of post-traumatic…
- Trial name
- NCT04363476
- Testing
- SHRED Osteoarthritis program
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Sport Injury Prevention Research Centre
Radiation Induced Fibrosis
Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer Patients
This study will evaluate the efficacy of losartan (LOS), an FDA-approved transforming growth factor beta-1 (TGF-β1) blocker, to decrease radiation induced fibrosis (RIF) in the breast and the lung of breast cancer patients…
- Trial name
- NCT05637216
- Testing
- Losartan 25 milligram capsule
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Shaw Cancer Center
Shoulder Impingement Syndrome
Conservative or Operative Treatment for the Shoulder Impingement Syndrome?
Study hypothesis: The impingement syndrome of the rotator cuff is a common cause of shoulder pain for which the most effective treatment is unknown.
- Trial name
- NCT00349648
- Testing
- acromioplasty
- Where
- Finland
- Volunteers
- 140 people
- Sponsor
- Kanta-Häme Central Hospital
Multiple Sclerosis, Muscular Dystrophy
Enhance Wellness for Individuals With Long-Term Physical Disabilities
This project is an adaptation trial, testing the efficacy of an evidence-based community wellness program, Enhance Wellness (http://www.projectenhance.org/enhancewellness.aspx), in a sample of middle and older-aged adults living…
- Conditions
- Multiple Sclerosis, Muscular Dystrophy, Post-polio Syndrome, Spinal Cord Injury
- Trial name
- NCT02815878
- Testing
- Enhance Wellness
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hip Osteoarthritis, Hip Necrosis
H1 Hip Resurfacing Arthroplasty
This is a prospective, non-randomized, consecutive series, multicentre, observational study to evaluate the clinical outcome of ceramic-on- ceramic hip resurfacing arthroplasty using the ceramic, non-porous, non-cemented H1 Hip…
- Conditions
- Hip Osteoarthritis, Hip Necrosis, Hip Dysplasia
- Trial name
- H1HRA (NCT03326804)
- Testing
- H1 Hip Resurfacing Arthroplasty
- Where
- 2 sites in United Kingdom
- Volunteers
- 250 people
- Sponsor
- Embody Orthopaedic Limited
Multiple Sclerosis, Spinal Cord Injury
Power Over Pain (POP) Study
Many individuals with multiple sclerosis (MS), spinal cord injury (SCI), acquired amputation (AMP), muscular dystrophy (MD), and low back pain (LBP) experience pain. There has been little research on how to treat this pain.
- Conditions
- Multiple Sclerosis, Spinal Cord Injury, Chronic Pain, Other and Unspecified Amputation Stump Complications
- Trial name
- POP (NCT01800604)
- Testing
- Pain Self-Management Intervention #1, Pain Self-Management Intervention #2, Pain Self-Management Intervention #3
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- University of Washington
Shoulder Dislocation
Comparison of Sedation/Analgesia: Midazolam/Morphine Vs Propofol/Remifentanil
For reduction of dislocated shoulder, sedation with propofol and remifentanil should give satisfactory operating conditions and pain relief, and significantly reduce the time to full recovery, compared with morphine and midazolam
- Trial name
- NCT00326352
- Testing
- Sedation with propofol and remifentanil
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Edinburgh
Trauma, Congenital Bone and Joint Abnormalities
Telemedicine Consultation in Trauma and Orthopedic
The purpose of this study is to determine whether telemedicine consultations (lead by standard scheme)allows to increase quality of anatomical and functional outcomes and improve clinical work-flow at patients with acute bone and…
- Conditions
- Trauma, Congenital Bone and Joint Abnormalities, Joint Diseases, Orthopedic Surgery Complications
- Trial name
- TeleTO (NCT00815243)
- Testing
- Telemedicine consultation, Treatment plan
- Where
- 5 sites in Ukraine
- Volunteers
- 300 people
- Sponsor
- Donetsk National Medical University
Subacromial Impingement Syndrome, Morphologic Change
Conservative Physiotherapy and Acromion Morphology
In this study, we aimed to evaluate the short-term effects of conservative physiotherapy in the subacromial impingement syndrome (SIS) and its relation to the acromion morphology.
- Trial name
- NCT04392934
- Testing
- a conservative physiotherapy protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hasan Kalyoncu University
Myelopathy Cervical, Cervical Spondylosis
Establishing the Validity and Reliability of a Dexterity Assessment Tool
Every year, thousands of Canadians are diagnosed with degenerative cervical myelopathy (DCM), a form of non-traumatic injury caused by spinal cord compression in the neck.
- Conditions
- Myelopathy Cervical, Cervical Spondylosis, Spinal Cord Compression
- Trial name
- NCT05910593
- Testing
- Dexterity Assessment Tool
- Where
- Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Osteoarthritis, Tendinopathy
Comparative Effectiveness of Particulate Versus Nonparticulate Steroid Injections for Musculoskeletal Conditions
This aims of this study are: 1. To determine if particulate or non-particulate corticosteroid injections are more effective at treating pain from musculoskeletal pathologies of the hip, glenohumeral joint, biceps tendon, or…
- Conditions
- Osteoarthritis, Tendinopathy, Impingement Shoulder
- Trial name
- NCT04278833
- Testing
- Triamcinolone or Betamethasone, Dexamethasone
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Stanford University
Vertebral Compression Fracture
Vertebral Augmentation Using VCFix Spinal System in Stand-alone Configuration
This study will review the safety and possibility of the VCFix Spinal System. This is a proof-of-concept study and an initial review of the surgical procedure and how well the VCFix device works, to who that the VCFix is safe and…
- Trial name
- NCT07259811
- Testing
- VCFix Spinal System in stand-alone configuration
- Where
- 2 sites in Germany
- Volunteers
- 10 people
- Sponsor
- Amber Implants B.V.
Shoulder Impingement Syndrome
Effects of Eccentric Training for Shoulder Abductors in Subjects With Shoulder Impingement Syndrome
The aim of the study was to evaluate the effect of eccentric strength training for shoulder abductors on force steadiness in subjects with subacromial impingement syndrome (SIS).
- Trial name
- NCT01090271
- Testing
- Isokinetic eccentric training
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Universidade Federal de Sao Carlos
Rotator Cuff Tear
The Effects of Kinesio Tape Application With Different Verbal Input Given to With Patients With Rotator Cuff Tear
The aim of the study to investigate the effectiveness KT application with different verbal inputs on pain, function and range of motion (ROM) on patient with rotator cuff tear.
- Trial name
- NCT03073655
- Testing
- Negative Verbal Input, Neutral Verbal Input, Positive Verbal Input
- Volunteers
- 87 people
- Sponsor
- Istanbul University
Hallux Rigidus, Hallux Limitus
Short Term Follow-up of Patient Implanted With the Metatarso-Phalangeal Prosthesis METIS®
The great toe is vital for normal, pain free ambulation. Decreased function associated with osteoarthritis of the first matatarsal phalangeal joint (MTP I) often called Hallux Rigidis or Hallux Limitus leading to a painful great…
- Conditions
- Hallux Rigidus, Hallux Limitus, Hallux Valgus, Osteoarthritis
- Trial name
- NCT01284985
- Where
- 4 sites in Czechia, Netherlands and 2 more
- Volunteers
- 60 people
- Sponsor
- Integra LifeSciences Services
Subacromial Impingement
Comparative Effects of Conscious Abdominal Contraction and Closed Kinetic Chain Exercises
Subacromial pain syndrome is a general term used to describe pain which originates from the shoulder and can spread towards the neck or down the arm. It's the most common reason for shoulder pain.
- Trial name
- NCT06106048
- Testing
- Closed kinetic chain exercises, Abdominal contraction exercises
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Sehat Medical Complex
Epicondylitis, Lateral
Epicondylar Muscle Activation in Tennis Players
Epicondylitis is one of the most common pathologies in tennis players. The search for an effective treatment is necessary for the relief of symptoms and the return to sports practice.
- Trial name
- NCT06160011
- Testing
- Electrical dry needling + Conventional physiotherapy, Dry needling + Conventional physiotherapy, Conventional physiotherapy
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Osteoporosis, Accidental Falls
Geriatric Health Exam Osteoporosis Screening
BACKGROUND: The World Health Organization Fracture Risk Assessment Tool (WHO FRAX®) Taiwanese calculator is freely available on line to help osteoporosis management.
- Conditions
- Osteoporosis, Accidental Falls, Fracture
- Trial name
- NCT01934387
- Where
- Taiwan
- Volunteers
- 1,319 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Proximal Humeral Fracture, Fracture Dislocation
Exactech Proximal Humerus Fracture Plate System Post Market Clinical Follow-up
The objective of this study is to collect and evaluate long-term clinical outcomes data in order to better understand the safety and performance of the Equinoxe Proximal Humerus Fracture Plates over time.
- Conditions
- Proximal Humeral Fracture, Fracture Dislocation, Non-Union Fracture
- Trial name
- NCT05703958
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Exactech
Fractures, Osteoporosis
OSTPRE-Fracture Prevention Study
The purpose of this study is to determine the effect of calcium 1000 mg/d and vitamin-D3 800 IU/d divided in two daily doses on the incidence of falls and fractures, bone mineral density and bone metabolism in postmenopausal…
- Trial name
- OSTPRE-FPS (NCT00592917)
- Testing
- calcium carbonate and cholecalciferol
- Where
- Finland
- Volunteers
- 3,432 people
- Sponsor
- Kuopio University Hospital
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