Clinical trials: Musculoskeletal Injury Trauma
HIV Infections, Alcohol Drinking
Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort: The 4F Study
The purpose of this study is to follow a cohort of HIV-infected adults who have alcohol and/or drug use to: 1) test the associations between alcohol (and illicit drugs and polypharmacy (multiple prescribed medications)) and falls…
- Conditions
- HIV Infections, Alcohol Drinking, Substance-Related Disorders, Bone Diseases
- Trial name
- NCT03414411
- Where
- United States
- Volunteers
- 251 people
- Sponsor
- Boston University
Spinal Cord Injury, Bone Loss
Effect of Teriparatide, Vibration and the Combination on Bone Mass and Bone Architecture in Chronic Spinal Cord Injury
Spinal cord injury (SCI) results in marked acute loss of bone. This study evaluates the effect of teriparatide (PTH) and the use of vibration as a form of mechanical stimulation on bone mass.
- Conditions
- Spinal Cord Injury, Bone Loss, Osteoporosis
- Trial name
- NCT01225055
- Testing
- Teriparatide, vibration
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Thomas J. Schnitzer
Spinal Cord Injuries, Osteoporosis
Simvastatin to Prevent SCI-Induced Bone Loss
This is a double blind, randomized, placebo -controlled clinical trial with the primary goal of determining the osteogenic benefits of simvastatin in acute SCI.
- Trial name
- NCT02946424
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Craig Hospital
Musculoskeletal Diseases, Median Nerve Disease
The Relationship Between Ultrasonographic Findings and Sleep Quality in Carpal Tunnel Syndrome
The aim of our study is to determine the relationship between disease severity and sleep quality in CTS patients and to compare the findings with healthy controls.
- Conditions
- Musculoskeletal Diseases, Median Nerve Disease, Carpal Tunnel Syndrome, Ultrasound
- Trial name
- NCT05742776
- Testing
- Assessment of Sleep Quality
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Lateral Epicondylitis
Treatment of Intractable Common Extensor Tendon Injury Using Mesenchymal Stem Cells (Allo-ASC)
The aim of this study is to evaluate the efficacy and safety of intra-tendon injection of allogeneic adipose-derived mesenchymal stem cells (Allo-ASC) in intractable common extensor tendinosis patients in comparison with a…
- Trial name
- NCT03449082
- Testing
- High concentration of Allo-ASC, Low concentration of Allo-ASC, Fibrin glue
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Carpal Tunnel Syndrome (CTS), Rheumatic Diseases
Comparison of Initial Treatment for Carpal Tunnel Syndrome Related to Rheumatic Diseases: Corticosteroid Injection Versus Nighttime Splinting
The aim of this study is to evaluate the effects of corticosteroid injection verses nighttime splinting as initial treatments on wrist function, quality of life, and sleep quality in patients with rheumatoid disease-related…
- Trial name
- NCT07042282
- Testing
- Nighttime Splinting, Corticosteroid Injection, Evaluation and Dynamic Adjustment
- Where
- 3 sites in China
- Volunteers
- 248 people
- Sponsor
- Yun Qian
Acute Kidney Injury, Abdominal Compartment Syndrome
Physiologic Signals and Signatures With the Accuryn Monitoring System (The Accuryn Registry)
The Accuryn Registry Study is an open-ended, global, multi-center, retrospective and prospective, single-arm data collection study with an FDA cleared device. The target population are cardiovascular surgery patients.
- Conditions
- Acute Kidney Injury, Abdominal Compartment Syndrome, Intraabdominal Hypertension, Cardiovascular Surgery
- Trial name
- NCT04585555
- Testing
- Accuryn Monitoring System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Potrero Medical
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Spinal Cord Injuries
Gut Peptides and Bone Remodeling in Individuals With Spinal Cord Injury
Both GLP-2 and GIP reduce bone resorption (measured as CTX) in healthy persons. In this study, we will investigate whether GLP-2 and GIP is reducing CTX in individuals with spinal cord injury.
- Trial name
- NCT05181150
- Testing
- Meal test, GIP, GLP-2
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Chronic Pain, Disability Physical
Physical Therapy to Treat Chronic Pain in Survivors of Trauma
This study will assess the effects of physical therapy (PT) for individuals who are survivors of trauma (SOT) and have chronic pain.
- Trial name
- NCT03933189
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Vermont
Degenerative Disc Disease, Trauma Injury
A Safety Study on Posterior Pedicle Screw System
The goal of this study is to assess the MUST MINI system safety in patient who will undergo a posterior cervical spine fusion intervention.
- Conditions
- Degenerative Disc Disease, Trauma Injury, Tumor
- Trial name
- MUST MINI PMS (NCT05821920)
- Testing
- MUST MINI system
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Medacta International SA
Multiple Sclerosis, Muscle Spasticity
Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe Spasticity.
This study is being conducted to compare the impact of somnolence (sleepiness) on cognition (awareness) as well as the safety and effectiveness of tizanidine hydrochloride capsules versus Zanaflex® (tizanidine hydrochloride…
- Conditions
- Multiple Sclerosis, Muscle Spasticity, Spinal Cord Injury, Stroke
- Trial name
- NCT00047580
- Testing
- tizanidine hydrochloride capsule
- Where
- 16 sites in United States
- Volunteers
- 120 people
- Sponsor
- Elan Pharmaceuticals
Spinal Cord Injuries, Myofascial Pain Syndrome
Effectiveness of Dry Needling as a Treatment of Shoulder Myofascial Pain Syndrome in Spinal Cord Injury Patients
Shoulder pain in people with spinal cord injury is one of the most prevalent in acute and chronic patients because of weakness in shoulder periarticular muscles, and also because of overuse of these part of the body in assistive…
- Conditions
- Spinal Cord Injuries, Myofascial Pain Syndrome, Shoulder Pain, Puncture
- Trial name
- NCT03709797
- Testing
- Dry needling in infraspinatus muscle
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de León
Orthopedic Disorder, Nontraumatic Injury
Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use
The investigator aims to conduct an open pilot study (N=6; 5 completers) to test the feasibility, acceptability, and credibility of an asynchronous web-based mind-body intervention (Toolkit for Resilient Life beyond Pain and…
- Conditions
- Orthopedic Disorder, Nontraumatic Injury, Substance Use, Upper Extremity Problem
- Trial name
- NCT06366633
- Testing
- Web-TIRELESS
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Jafar Bakhshaie
Knee Osteoarthritis
FAST and PSFS: Assessment and Validation of Two Functional Scales in Patients With Knee OA in Singapore
The new National One-Rehab framework mandates the use of the Patient-Specific Functional Scale (PSFS) as an outcome measure to track patients' rehabilitation progress.
- Trial name
- NCT05590663
- Testing
- Physiotherapy
- Where
- Singapore
- Volunteers
- 150 people
- Sponsor
- SingHealth Polyclinics
Compartment Syndrome
Study of New Catheter & Pressure Monitor System to Help Prevent Compartment Syndrome From Developing in the Injured Leg
An investigation of a new catheter and pressure monitor system that may help to prevent a complication called compartment syndrome from developing in an injured leg.
- Trial name
- TS2 (NCT00681616)
- Testing
- Compartment Monitoring System (CMS), Compartment Monitoring System with Active Fluid Removal, Compartment Monitoring System without fluid removal
- Where
- 13 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Twin Star Medical, Inc.
Musculoskeletal Injury, Hypogonadism
Adaptions and Resiliency to Multi-Stressor OpeRations
Non-combat-related muscle, tendon and bone injuries are the most common injuries suffered by military personnel, particularly in new recruits.
- Conditions
- Musculoskeletal Injury, Hypogonadism, Hormonal Contraception
- Trial name
- ARMOR (NCT06455969)
- Testing
- Goserelin 3.6 MG, Multi-Stressor Training, Testosterone gel (AndroGel 5g)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bradley Nindl
Concussion, Brain, Musculoskeletal Pain
The Impact of Eye and Body Training on the Injury Rate of Concussions in Female Soccer Players
The research project aims to find out how special training influences the frequency and severity of injuries among female footballers in the top Swiss league.
- Trial name
- NCT06473883
- Testing
- Training recommendation
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- BrainCare Medical Group
Abdominal Compartment Syndrome, Intra-abdominal Hypertension
Peritoneal Vacuum Therapy to Reduce Inflammatory Response From Abdominal Sepsis/Injury
This pilot study will evaluate the effectiveness in actively removing the peritoneal fluid through the use of a commercial suction device compared to passive drainage of the same peritoneal fluid drained through standard surgical…
- Trial name
- SAD (NCT01355094)
- Testing
- KCI AbThera, "Stampede" VAC
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Acute Spinal Cord Injury, Spinal Cord Injuries
Spasticity and Functional Recovery After SCI
Spasticity is one of the most common symptoms manifested in humans with spinal cord injury (SCI). However, the neural mechanisms underlying the development of spasticity over time after an acute SCI are not yet understood.
- Trial name
- NCT06030531
- Testing
- Measures of spasticity, connectivity and analysis of single nucleotide polymorphisms and biomarkers of inflammation, Analysis of biomarkers
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab