Clinical trials: Musculoskeletal Injury Trauma
Arthritis
Post-traumatic Arthritis Associated With Joint Injury
Arthritis is the nation's most common cause of disability. An estimated 50 million U.S. adults (about 1 in 5) report doctor-diagnosed arthritis. Twenty three million U.S.
- Trial name
- NCT01792791
- Testing
- Tissue sample collection at the time of surgery
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duke University
Shoulder Impingement, Shoulder Pain
"Validation and Reability of the Munich Shoulder Questionnaire Into Turkish Patients"
The purpose of this study was to translate and culturally adapt the MSQ to Turkish language and test the validity and reliability of Turkish version of MSQ in shoulder dysfunction patients.
- Conditions
- Shoulder Impingement, Shoulder Pain, Shoulder Injury
- Trial name
- MSQ (NCT03956147)
- Testing
- Munich Shoulder Questionnaire
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Groin Injury, Tendinopathy
Pubalgia and Adductor Tendinopathies Refractory to Medical Treatment
Pubalgia is a pain syndrome located in the groin area. This syndrome is mainly described in young male athletes and typically affect the superficial muscles defining the boundaries of the femoral triangle, i.e.
- Trial name
- PETRA (NCT03496649)
- Testing
- Dysport 500 Unit Powder for Injection
- Where
- France
- Volunteers
- 4 people
- Sponsor
- University Hospital, Bordeaux
SCI - Spinal Cord Injury, PD - Parkinson's Disease
Differential Assessment of Hypertonia
Spasticity and rigidity are common symptoms of central nervous system injuries, such as spinal cord injury and Parkinson's disease, and result in distinct patterns of increased resistance during passive joint movements.
- Trial name
- NCT06596187
- Testing
- Continuous passive motion device (CPM) of ankle - fast, Continuous passive motion device (CPM) of ankle - slow
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Injury;Sports, Muscle Soreness
Effects of Percussion Therapy on the Biomechanics of Pickleball Movement
With increased demand on pickleball as a recreational exercise, it is of interest in investigating the biomechanical characteristics of pickleball and determining the impacts of percussion therapy on them.
- Trial name
- NCT07005934
- Testing
- Theragun Prime
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Point Loma Nazarene University
Spine Disease, Spinal Stenosis
CEUS For Intraoperative Spinal Cord Injury
Spinal cord injury following posterior decompression in patients suffering from chronic, cervicothoracic spinal cord compression is a known complication with multiple etiologies.
- Conditions
- Spine Disease, Spinal Stenosis, Spinal Injury, Spinal Cord Diseases
- Trial name
- NCT05530798
- Testing
- Definity Perflutren Lipid Microsphere Ultrasound Contrast
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Proximal Hamstring Tendinopathy, Tendinopathy
Efficacy of Eccentric Versus Isometric Exercise in Reducing Pain in Runners With Proximal Hamstring Tendinopathy
Tendon injuries are the most common injuries in sports. They are difficult to treat and cause prolonged absence and decreased athlete performance. Proximal hamstring tendinopathy (PHT) is one of them.
- Conditions
- Proximal Hamstring Tendinopathy, Tendinopathy, Eccentric Exercise, Isometric Exercise
- Trial name
- NCT04683107
- Testing
- Eccentric protocol, Isometric protocol
- Volunteers
- 42 people
- Sponsor
- University of Haifa
Musculoskeletal Injury
Cryotherapy and Joint Biomechanics During Running
The purpose of this study is to determine the immediate effects of cryotherapy on the lower extremity biomechanics during running.
- Trial name
- NCT01740661
- Testing
- Cryotherapy, Control
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Fibromyalgia, PTSD
Group Therapy for Fibromyalgia:the Effectiveness of Mindfulness -Based VS Cognitive-behavioral Therapy
This study was conducted as part of a collaboration between the Maccabi Health Fund and Bar Ilan University. Fibromyalgia is a chronic pain disorder, highly co-morbid with depression, stress, and anxiety.
- Conditions
- Fibromyalgia, PTSD, Depression, Stress
- Trial name
- NCT04265196
- Testing
- cognitive behavioral group therapy, Mindfulness-based group therapy
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Bar-Ilan University, Israel
Low Back Pain, Knee Arthritis Osteoarthritis
How Patient Education Helps Patients With Chronic Musculoskeletal Disorders Stick to Home Exercise for Pain Relief.
The study aims to evaluate the effectiveness of a structured patient education program in enhancing adherence to prescribed home exercise regimens in individuals with chronic low back pain, knee osteoarthritis, and shoulder pain.
- Conditions
- Low Back Pain, Knee Arthritis Osteoarthritis, Shoulder Disease, Shoulder and Upper Arm Injury
- Trial name
- NCT07764354
- Testing
- Educational with musculoskeletal condition, Standard physical therapy program
- Where
- Saudi Arabia
- Volunteers
- 120 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Osgood-Schlatter Disease, Apophysitis
A Comparison of Two Different Treatment Approaches for Adolescents With Osgood Schlatter
The most common growth-related injury is Osgood Schlatter, which affects up to 1 in 5 physically active adolescents. It can cause long-term pain and potential discontinuation of sports and physical activity, with sequela well…
- Conditions
- Osgood-Schlatter Disease, Apophysitis, Osteochondrosis; Tibia, Physeal Injury
- Trial name
- SOGOOD (NCT05174182)
- Testing
- A novel treatment approach, Usual care
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Hvidovre University Hospital
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Plus Finasteride Treatment After Spinal Cord Injury
The purpose of this study is to determine whether testosterone plus finasteride treatment will improve musculoskeletal health, neuromuscular function, body composition, and metabolic health in hypogonadal men who have experienced…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injuries
- Trial name
- NCT02248701
- Testing
- Testosterone Enanthate, Finasteride
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Hemiparesis After Stroke, Traumatic Brain Injury
Partial Blocks of Rectus Femoris and Soleus With Botulinum Toxin Type A (Xeomin®) to Improve Gait in Hemiparesis
The most common motor deficiency after stroke or traumatic brain injury is hemiparesis. Most hemiparetic patients recover walking, but rarely with a speed permitting easy ambulation outdoors with family or friends.
- Trial name
- GENUFLEX (NCT03119948)
- Testing
- Botulinum toxin injection
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoarthritis, Knee
Clinical Trial to Evaluate the Efficacy and Safety of MegaCarti® in Knee Cartilage Defects
Subjects aged 50 to 65 years with knee cartilage defects will undergo microfracture treatment for cartilage regeneration and MegaCarti® will be applied.
- Trial name
- NCT06249828
- Testing
- MegaCarti®, Microfracture
- Where
- 7 sites in South Korea
- Volunteers
- 61 people
- Sponsor
- L&C Bio
Musculoskeletal Injury
Use of an Integrated Orthotic and Rehabilitation Initiative for Treatment of Lower Extremity Musculoskeletal Disorders
The Intrepid Dynamic Exoskeletal Orthosis (IDEO) is a custom, energy storage and return ankle orthosis proven to improve functional ability when coupled with a customized high-intensity rehabilitation program.
- Trial name
- NCT05780502
- Testing
- Passive Dynamic Brace
- Where
- United States
- Volunteers
- 370 people
- Sponsor
- Wake Forest University Health Sciences
Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree
The Effect of Low-Intensity Blood Flow Restriction Therapy on the Management of Acute Ankle Sprains
The primary objective of this study is to evaluate the feasibility of implementing BFR in the rehabilitation treatment of isolated ankle sprains as well as to evaluate the clinical benefits of BFR when compared to standard…
- Conditions
- Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree, Musculoskeletal Injury
- Trial name
- NCT05596162
- Testing
- Blood Flow Restriction Therapy, Standard Physical Therapy
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Covid19, Trauma
Impact of COVID-19 Pandemic on Orthopaedic Practice
The COVERT Collaborative is led by a group of academic surgeons that is looking into the impact of the unprecedented COVID-19 pandemic on Trauma and Orthopaedic practice.
- Conditions
- Covid19, Trauma, Orthopedic Disorder, Anesthesia
- Trial name
- COVERT (NCT05026788)
- Testing
- type of treatment
- Where
- United Kingdom
- Volunteers
- 5,000 people
- Sponsor
- Imperial College Healthcare NHS Trust
Musculoskeletal Injury, Quality of Life
Quality of Life and Life Satisfaction in Pediatric and Adolescent Gymnasts Through Injury
This study aims to assess the quality and life and life satisfaction of pediatric and adolescent gymnasts throughout their musculoskeletal injury recovery.
- Trial name
- NCT05110729
- Where
- United States
- Volunteers
- 1,218 people
- Sponsor
- University of Colorado, Denver
Growth Hormone Treatment, Growth Hormone Deficiency
Growth Hormone Deficiency in Mild Traumatic Brain Injury
The goal of this randomized control trial is to test if growth hormone therapy is a safe and effective treatment for patients suffering from growth hormone deficiency and persistent post-concussion symptoms.
- Conditions
- Growth Hormone Treatment, Growth Hormone Deficiency, Concussion, Mild, Concussion Post Syndrome
- Trial name
- NCT05660356
- Testing
- Growth Hormone
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Musculoskeletal Injury
Body Asymmetries in Athletes and Injury Risk
The study will assess the associations between various asymmetries (strength, flexibility, balance, etc.) in different athletes.
- Trial name
- TELASI (NCT03518827)
- Testing
- Asymmetry measurement
- Where
- 2 sites in Slovenia
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- University of Primorska