Clinical trials: Musculoskeletal Injury Trauma
Musculoskeletal Injuries
Pre- and Post-neuromusculoskeletal Injury Risk Evaluation for Return-to-Duty Enhancement
The purpose of this study is to develop comprehensive and efficient pre- and post- musculoskeletal injury (MSKI) risk assessments for Service members, incorporating both objective and subjective measures.
- Trial name
- PREPARE (NCT05111925)
- Testing
- PREPARE Initial Clinical Assessment - Pilot (two iterations), PREPARE Initial Clinical Assessment - Pre-Injury (one iteration), PREPARE Initial Clinical Assessment - Post-Injury (up to three iterations)
- Where
- 2 sites in United States
- Volunteers
- 2,690 people, healthy volunteers welcome
- Sponsor
- Womack Army Medical Center
Lateral Epicondylitis, Work Related Injury
Randomized Trial of Iontophoresis Versus Injection of Corticosteroids for Lateral Epicondylitis
The purpose of this project is to compare different treatment options for lateral epicondylitis. Lateral epicondylitis is a pain condition involving extensor muscles fo the forearm originating from the lateral epicondyle.
- Trial name
- NCT00257634
- Testing
- dexamethasone to injury site
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Henry Ford Health System
Spinal Cord Injury, Spasticity
The Effect of Whole Body Vibration on Spasticity in Persons With Spinal Cord Injury
Extended periods of tilt table standing have been observed to improve spasticity in individuals with spinal cord injury (SCI). The purpose of this study is to determine the effect of three sessions of whole body vibration while…
- Trial name
- NCT02127606
- Testing
- Vibration with tilt-table standing
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Kessler Foundation
Muscle Weakness, Problems Moving Their Arms and Legs
Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults
People with cerebral palsy (CP), muscular dystrophy (MD), spina bifida, or spinal cord injury often have muscle weakness, and problems moving their arms and legs.
- Trial name
- NCT06998134
- Testing
- Extension assist knee ankle foot orthosis (EA-KAFO)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Compartment Syndrome
Phase I, Arteriocyte Magellan MAR01 Therapy - Compartment Syndrome and Battlefield Trauma
Compartment syndrome (CS) is a condition resulting from increased pressure within a compartment, which compromises circulation and can lead to critical limb ischemia.
- Trial name
- Magellan MAR01 (NCT01837264)
- Testing
- Magellan®
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Arteriocyte, Inc.
Spondylolisthesis, Lumbar Region, Spinal Trauma With Neurological Deficit
Adult Patient Outcomes After Spine Surgery With Fibergraft BG Putty/Viper Prime
The Viper Prime/Expedium spine systems are intended to provide immobilization and stabilization of spinal segments in skeletally mature patients as an adjunct to fusion in the treatment of acute and chronic instabilities or…
- Conditions
- Spondylolisthesis, Lumbar Region, Spinal Trauma With Neurological Deficit, Degeneration of Lumbar Intervertebral Disc
- Trial name
- NCT06704906
- Testing
- Use of Viper Prime/Expedium system with Fibergraft BG Putty
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Nitin Agarwal
Diabetes, Prediabetes
Meta-Analyses of the Effect of Plant Protein Versus Animal Protein on Cardiometabolic Risk
Vegetarian diets have been associated with a reduced risk of preventable diseases such as type 2 diabetes and cardiovascular disease. These effects may be mediated through direct or indirect pathways.
- Conditions
- Diabetes, Prediabetes, Metabolic Syndrome, Dysglycemia
- Trial name
- NCT02037321
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Traumatic Brain Injuries
Assessment of the Effects of Early Proprioceptive Stimulations in Patients With Severe Traumatic Brain Injury
"Severe traumatic brain injury (TBI) is a serious condition, common in young adults. It leads to sensorimotor and cognitive sequelae that hinder social reintegration.
- Trial name
- TC-Mouv (NCT05094999)
- Testing
- Proprioceptive stimulations
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Whiplash Injury of Cervical Spine, Muscle Weakness
Influence of Directional Preference on Movement Coordination Deficits in Individuals With Whiplash Associated Disorders
The aim of this prospective observational study is to investigate whether the presence or absence of directional preference impacts movement coordination impairments as measured in patients with Whiplash Associated Disorders…
- Trial name
- NCT06143228
- Where
- 2 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- D'Youville College
Scoliosis, Spinal Deformity
Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations
Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain.
- Conditions
- Scoliosis, Spinal Deformity, Acute Pain, Chronic Pain
- Trial name
- BBESPB (NCT04697498)
- Testing
- Bilateral bi-level Erector spine plane block, General anaesthesia
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Lviv National Medical University
Major Depressive Disorder, Dysthymia
Project to Improve Symptoms and Mood in People With Spinal Cord Injury
Depression is likely the most prevalent and disabling psychological complication associated with spinal cord injury (SCI). Yet no controlled depression treatment trials have been performed in this population.
- Conditions
- Major Depressive Disorder, Dysthymia, Spinal Cord Injuries
- Trial name
- PRISMS (NCT00592384)
- Testing
- venlafaxine XR
- Where
- 6 sites in United States
- Volunteers
- 133 people
- Sponsor
- University of Washington
Musculoskeletal Injury
Use of a Self-Directed Exercise Program (SDEP) Following Selected Lower Extremity Fractures
The purpose of this study is to compare the effectiveness and value of clinic-based physical therapy (PT) and a home-based, self-directed exercise program (SDEP).
- Trial name
- NCT04612478
- Testing
- Self-Directed Exercise Program, Clinic-Based Physical
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Wake Forest University Health Sciences
Acute Spinal Cord Injury.
Risedronate for the Prevention of Osteoporosis in People With Spinal Cord Injury.
The purpose of this study is to find out if Risedronate works to prevent osteoporosis after spinal cord injury.
- Trial name
- NCT00150696
- Testing
- Risedronate
- Where
- 2 sites in Canada
- Volunteers
- 38 people
- Sponsor
- Toronto Rehabilitation Institute
Hallux Limitus
Kinetic Control Versus Dynamic Taping on First Metatarsophalangeal Joint in Athletes With Functional Hallux Limitus
This study is conducted to investigate and compare the effect of adding either kinetic control retraining or dynamic taping to the standard treatment program on first metatarsophalangeal joint dorsiflexion active range of motion…
- Trial name
- NCT07692113
- Testing
- the standard treatment, Dynamic taping, kinetic control
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Rhabdomyolysis, Acute Kidney Injury
Use of a Vacuum Mattress During Laparoscopic Sleeve Gastrectomy to Reduce the Concentration of Rhabdomyolysis Markers and Acute Renal Failure
This prospective clinical trial aimed to assess the usefulness of the usage of a vacuum mattress during laparoscopic sleeve gastrectomy (LSG) in the reduction of levels of rhabdomyolysis markers (myoglobin, creatine kinase…
- Conditions
- Rhabdomyolysis, Acute Kidney Injury, Bariatric Surgery Candidate
- Trial name
- NCT06338423
- Testing
- vacuum mattress, Standard Mattress
- Where
- Poland
- Volunteers
- 1,184 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Musculoskeletal Injury
Can Immediate Post-injury Fluoxetine Improve the Recovery Trajectories of Victims in Bodily Trauma?
With this prospective double-blinded, placebo controlled clinical trial we hypothesize that immediate (post-injury) intervention with Fluoxetine will prevent/mitigate the development of negative psychiatric symptomology such as…
- Trial name
- NCT06046859
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Florida
Work-Related Condition, Burnout, Caregiver
Effectiveness of the Healthy Workplace Participatory Program With Peer-led Teams in Public Sector Healthcare Facilities
Safety \& Health through Integrated, Facilitated Teams (SHIFT) is an intervention study to enhance employee health, safety, and well-being in public sector healthcare institutions in New England.
- Conditions
- Work-Related Condition, Burnout, Caregiver, Work-related Injury, Musculoskeletal Pain
- Trial name
- SHIFT (NCT04251429)
- Testing
- CPH-NEW Healthy Workplace Participatory Program
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Lowell
Shoulder Pain
Trial for Shoulder Pathology and Pain in Chronic SCI
This research study will investigate in a 12-week home exercise program to see whether it is effective in improving shoulder pathology and reducing shoulder pain in persons with chronic spinal cord injury.
- Trial name
- NCT03521856
- Testing
- shoulder exercise, education
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Miami
Acute Spinal Cord Injury
Early FES Cycling in Acute Spinal Cord Injury for Neuromuscular Preservation and Neurorecovery
Spinal cord injury (SCI) is a devastating condition that often leads to paralysis and multiple health problems such as muscle wasting, bone loss and spasticity.
- Trial name
- NCT05255679
- Testing
- Early FES, Delayed FES
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of Alberta
Glenohumeral Internal Rotation Deficit (GIRD)
Effect of Joint Mobilization and Movement Control Exercises on Shoulder Pain and Function in Fast Bowlers (RCT)
The goal of this clinical trial is to determine combined effects of the Kinetic control for shoulder on pain, range, and function among fast bowlers.
- Trial name
- RCT (NCT07229274)
- Testing
- Kinetic control for shoulder internal rotation with mobilization with movement, stretches, strengthening and mobilization with movement
- Where
- 2 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- Lahore University of Biological and Applied Sciences