Clinical trials: Musculoskeletal Injury Trauma
Anterior Cruciate Ligament Injury, Patellofemoral Pain Syndrome
Sports Rehabilitation Therapy for Knee Joint Sports Injuries: A Case Study of Anterior Cruciate Ligament Injury and Patellar Chondromalacia
The primary objective of this clinical trial is to verify the superiority of a digital diagnosis and treatment system for the conservative management of knee sports injuries-based on wearable sensors, machine vision, and large…
- Trial name
- NCT07423819
- Testing
- Muscle Strength Training, Lower limb balance and stability exercises, Stretching and Relaxation
- Where
- 4 sites in China
- Volunteers
- 160 people
- Sponsor
- Peking University Third Hospital
Cardiovascular Risk Factor, Diabetes Mellitus, Type 2
Evaluation of a Physical Activity Referral Scheme
The study will evaluate the effectiveness of a co-developed exercise referral scheme. Participants will be recruited to one of three groups 1. Co-developed exercise referral scheme, 2. Usual care exercise referral scheme, 3.
- Conditions
- Cardiovascular Risk Factor, Diabetes Mellitus, Type 2, Anxiety, Depression
- Trial name
- NCT03490747
- Testing
- Physical activity referral scheme, Usual care exercise referral scheme
- Where
- United Kingdom
- Volunteers
- 68 people
- Sponsor
- Paula Watson
Temporomandibular Joint Disorders
Alloplastic Total Temporomandibular Joint (TMJ) Replacement Registry
Prospective data will be collected in approximately 200 patients treated with an TMJ replacement. Patients will be followed up according to the standard (routine) for up to 5 years after the treatment.
- Trial name
- NCT03991728
- Where
- 23 sites in Brazil, Colombia and 13 more
- Volunteers
- 200 people
- Sponsor
- AO Innovation Translation Center
Evaluation of TMJ With CBCT in Pediatric Trauma Patients, Temporomandibular Joint Disorders
The Influence of Pediatric Dental Trauma on Temporomandibular Joint Disorders: A Retrospective Clinical and Radiological Analysis
This retrospective study received ethical approval from the Ethics Committee of Dicle University Faculty of Medicine, Diyarbakır, Turkey (Decision No:03.05.2012-567).
- Conditions
- Evaluation of TMJ With CBCT in Pediatric Trauma Patients, Temporomandibular Joint Disorders, Dental Trauma, Anterior Teeth Fracture
- Trial name
- DentTraumaTMJ (NCT07268443)
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Dicle University
Spinal Cord Injury, Spasticity
Extracorporeal Shockwave Therapy as an Additional Treatment for Spasticity Secondary to Spinal Cord Injury
Spasticity is a common consequence of spinal cord injury and can have a profound impact on quality of life. The goal of this study is to learn if an intervention called focused extracorporeal shockwave therapy can enhance the…
- Trial name
- NCT07894991
- Testing
- Focused extracorporeal shockwave therapy, Botulinum toxin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kessler Foundation
Musculoskeletal Pain
Vitamin D to ENhance TraUma REcovery
The main objective of this study is to determine whether the administration of a single dose of Vitamin D in the Emergency Department following a motor vehicle collision can improve musculoskeletal pain severity as well as reduce…
- Trial name
- VENTURE (NCT05458024)
- Testing
- Vitamin D 2
- Where
- 4 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Shoulder Pain, Shoulder Impingement
Assessment of Shoulder Rehabilitation Practices and Documentation Protocols at Riphah Rehabilitation Center
This study aims to evaluate Riphah Rehabilitation Center's shoulder rehabilitation procedures and documentation guidelines. The study will specifically assess the efficacy of shoulder rehabilitation procedures, their methodology…
- Conditions
- Shoulder Pain, Shoulder Impingement, Rotator Cuff Injury
- Trial name
- NCT06773442
- Testing
- Rehabilitation Practices Group, Documentation Protocols Group
- Where
- 2 sites in Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Spinal Cord Injury
Bone Strength After Spinal Cord Injury
Background: After a traumatic spinal cord injury, a severe bone loss in the paralyzed extremities is observed. This leads to a osteoporosis which is connected to a high fracture risk.
- Trial name
- NCT01853488
- Testing
- DXA, pQCT
- Where
- Switzerland
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Orthopedic Disorder, Trauma Injury
X-BS Ortho Bone Graft Study
Randomised investigation of the osteoconductive performance and safety of CE-marked FDBS bone graft (GraftR3®), with contextual reference to CE-marked IBS (MBCP® Putty), in the filling of orthopaedic bone defects.
- Conditions
- Orthopedic Disorder, Trauma Injury, Extremity Injury
- Trial name
- NCT06326827
- Testing
- FDBS (GraftR3®), IBS (MBCP® Putty)
- Volunteers
- 200 people
- Sponsor
- Advanced Medical Solutions Ltd.
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Musculoskeletal Pain, Musculoskeletal Pain Disorder
Dutch Version Fear-Avoidance Component Scale (FACS)
Chronic musculoskeletal disorders such as low back and neck pain are responsible for an enormous global burden. Fear-avoidance (FA) can be a predictor for the transition from subacute to chronic low back pain.
- Conditions
- Musculoskeletal Pain, Musculoskeletal Pain Disorder, Fear of Pain, Fear of Injury
- Trial name
- NCT03994861
- Testing
- Assessment of disability and behavior (by questionnaires)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Osteoarthritis, Knee, Osteochondral Defect
The Impact of Covid-19 on Patients Waiting for Knee Surgery
The Covid-19 pandemic has led to the postponement and cancellation of elective orthopaedic surgeries worldwide. These delays to elective procedures combined with ongoing demand have led to increasingly longer waiting list times.
- Conditions
- Osteoarthritis, Knee, Osteochondral Defect, Cartilage Injury, Cartilage Damage
- Trial name
- NCT05124613
- Testing
- Survey
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- University of Manchester
Injuries
Incidence of Acute Injuries in Boxing
A prospective cohort study with 9 months follow up was carried out in 2017-2018. Boxers of both sexes 18 years and older from all 7 boxing clubs in Iceland were invited to participate in the study.
- Trial name
- NCT06264323
- Where
- Iceland
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Diaphragm Injury, Muscle Weakness
Electromyography for Diaphragm Effort
Mechanical ventilation may be necessary to save the life of a patient due to an accident, pneumonia or surgery. The ventilator then temporarily takes over the function of the respiratory muscles.
- Conditions
- Diaphragm Injury, Muscle Weakness, Weaning Failure, Physiological Stress
- Trial name
- Edi2Pdi (NCT03580720)
- Testing
- Inspiratory threshold loading protocol
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Osteoarthritis, Knee
Clinical Trial to Evaluate the Efficacy and Safety of MegaCarti® in Knee Cartilage Defects
Subjects aged 50 to 65 years with knee cartilage defects will undergo microfracture treatment for cartilage regeneration and MegaCarti® will be applied.
- Trial name
- NCT06249828
- Testing
- MegaCarti®, Microfracture
- Where
- 7 sites in South Korea
- Volunteers
- 61 people
- Sponsor
- L&C Bio
Aging, Rehabilitation
Physical Function of Older Citizens During Municipality-based Rehabilitation
When choosing outcomes to assess rehabilitation's effect or progress, it is essential to consider the constructs being measured and their value to the patient and the psychometric properties.
- Conditions
- Aging, Rehabilitation, Frailty, Sarcopenia
- Trial name
- NCT04862481
- Where
- Denmark
- Volunteers
- 115 people
- Sponsor
- University College Absalon
Flexible Flatfoot, Lumbar Spine Injury
Relationship Between Flexible Flat Foot and Lumbar Proprioception
The purpose of this study was to determine the relationship between flexible flatfoot and lumbar proprioception.
- Conditions
- Flexible Flatfoot, Lumbar Spine Injury, Proprioceptive Disorders
- Trial name
- NCT06879756
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Cairo University
Centreal Neurological Condition, Acquired Brain Injury (Including Stroke)
Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower Extremities
Spasticity is an umbrella term for impairments of muscle tone and control in people with damage to the brain and spinal cord. It is highly prevalent and results in pain, stiffness, and contribute to difficulties in activities of…
- Conditions
- Centreal Neurological Condition, Acquired Brain Injury (Including Stroke), Multiple Sclerosis, Spinal Cord Injury
- Trial name
- ICE (NCT07303582)
- Testing
- Cryoneurolysis, Botulinum toxin
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Oxford University Hospitals NHS Trust
Injury of Musculoskeletal System
Study of the Effect of Kinesio Taping and Proprioceptive Exercise on the Stability of Ankle in Amateur Soccer Players
Soccer is a sport that attracts many participants and leads to a substantial number of injuries, especially of the ankle. Enhancement of functional joint stability by kinesio taping proprioceptive training may be important both…
- Trial name
- NCT02863562
- Testing
- Kinesio taping, Proprioceptive exercises
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Abdominal Compartment Syndrome, Intra-abdominal Hypertension
Peritoneal Vacuum Therapy to Reduce Inflammatory Response From Abdominal Sepsis/Injury
This pilot study will evaluate the effectiveness in actively removing the peritoneal fluid through the use of a commercial suction device compared to passive drainage of the same peritoneal fluid drained through standard surgical…
- Trial name
- SAD (NCT01355094)
- Testing
- KCI AbThera, "Stampede" VAC
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary