Clinical trials: Musculoskeletal Injury Trauma
Fibromyalgia, Chronic Pain Syndrome
HBOT Effect on Chronic Pain Syndrome With a History of Psychological Trauma
The aim of the study is to evaluate the effect of hyperbaric oxygen therapy (HBOT) on 2 types of patients' population suffering from chronic pain syndrome (Fibromyalgia): patients with history of psychological trauma and patients…
- Trial name
- HBOTCSA (NCT03376269)
- Testing
- HBOT, Psychotherapy
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Carpal Tunnel Syndrome, Psoriatic Arthritis
Carpal Tunnel Syndrome in Patients With Psoriatic Arthritis; Ultrasonography and Magnetic Resonance Imaging Findings
This study aimed to investigate relationship between CTS diagnosis with electrodiagnostic studies and median nerve's cross-sectional area measered by US and MRI in PsA patients.
- Trial name
- NCT05086042
- Testing
- Ultrasonography, Magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Acute Kidney Injury, Crush Injury
The Effects of Dexmedetomidine and Remifentanil on Kidney Injury After Muscle Compression Injury in Rats
The goal of this interventional preclinical study is to evaluate the potential protective effects of two intravenous anesthetic agents-dexmedetomidine and remifentanil-on kidney function in the context of muscle crush injury…
- Conditions
- Acute Kidney Injury, Crush Injury, Rhabdomyolysis
- Trial name
- NCT07094165
- Testing
- Dexmedetomidine, Remifentanil, Laparotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ankara City Hospital Bilkent
Work-related Injury
Patient Handling Techniques and New Technology for Health Care Workers
Patient handling is a major risk-factor for the development of musculoskeletal injuries in healthcare providers. To have a significant impact on injury reduction related to patient handling will require the incorporation of…
- Trial name
- NCT06285786
- Testing
- Ergonomic Training on Patient Handling Techniques
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of New Brunswick
Osteoarthritis Shoulder, Rotator Cuff Syndrome of Shoulder and Allied Disorders
FX Shoulder Prospective Clinical Study
Prospective Multi-Center Registry on study subjects with implanted devices marketed and legally commercialized in the USA by FX Shoulder Solutions.
- Conditions
- Osteoarthritis Shoulder, Rotator Cuff Syndrome of Shoulder and Allied Disorders, Fracture, Shoulder
- Trial name
- NCT06078865
- Testing
- FX Artificial Shoulder Prosthesis
- Where
- 4 sites in United States
- Volunteers
- 600 people
- Sponsor
- FX Shoulder Solutions
Muscle Atrophy, Cachexia
Vitamin K2 Supplements for Muscle Recovery
Ankle injury is one of the most common injuries which can have long term consequences. Ankle immobilization is often applied for up to six weeks to ensure healing of the soft tissue and fractured bones after such an injury.
- Trial name
- Recovery (NCT05161975)
- Testing
- Vitamin K2
- Where
- 2 sites in Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Spasticity, Muscle, Spinal Cord Injuries
Long-term Efficacy of Spasticity-correcting Surgery and Botulinum Toxin Injections for Upper Limb Spasticity Treatment
Spasticity - a variety of motor over-activity and part of the upper motor neuron syndrome - is a common cause of impaired motor function after brain injuries of different etiologies.
- Conditions
- Spasticity, Muscle, Spinal Cord Injuries, Traumatic Brain Injury, Stroke
- Trial name
- NCT03910101
- Testing
- Hand surgery and intensive rehabilitation
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Vastra Gotaland Region
Scoliosis, Spinal Deformity
Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations
Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain.
- Conditions
- Scoliosis, Spinal Deformity, Acute Pain, Chronic Pain
- Trial name
- BBESPB (NCT04697498)
- Testing
- Bilateral bi-level Erector spine plane block, General anaesthesia
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Lviv National Medical University
Spinal Cord Injuries, Spasticity, Muscle
Carry-over Effects of Repetitively Applied Transcutaneous Spinal Cord Stimulation on Spasticity
Spinal cord injury is a devastating condition, causing substantial impairment of vital body functions caudal to the lesion. A major cause of disability stems from spasticity, a common secondary sequelae.
- Trial name
- SCS-CorE (NCT03815721)
- Testing
- Stimulette r2x+
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Ultrasound, Shoulder Dislocation
Musculoskeletal Ultrasound for Diagnosis of Shoulder Dislocation Reduction
This study will compare the current standard of care post reduction plain film x ray for confirmation of shoulder reduction to point of care ultrasound.
- Conditions
- Ultrasound, Shoulder Dislocation, Musculoskeletal Injury
- Trial name
- NCT04703517
- Testing
- Point of care ultrasound
- Sponsor
- Rutgers, The State University of New Jersey
Non-union or Delayed Healing Fractures
Evaluation of the Risk for Radiographic and Clinical Nonunion in Patients With Previous Bisphosphonates Therapy.
Dose and duration of bisphosphonate therapy will increase the likelihood that patients experience delayed healing of non-union fractures.
- Trial name
- NCT01731535
- Where
- United States
- Sponsor
- University of Wisconsin, Madison
Bone Loss
Efficacy and Safety of Zoledronic Acid in Acute Spinal Cord Injury: Prevention of Bone Loss
This is a double-blind, randomized, placebo-controlled trial of zoledronic acid, 5mg, to be administered intravenously to people who have suffered an acute spinal cord fracture.
- Trial name
- NCT00844480
- Testing
- zoledronic acid
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Thomas J. Schnitzer
Pelvic Floor Disorders, Urinary Incontinence
Maternal Musculoskeletal Factors of the Hip, Lumbopelvic, Abdominal and Pelvic Floor Regions and Their Association With Mode of Delivery and Postpartum Pelvic Floor Dysfunction
This prospective observational cohort study aims to investigate the association between maternal musculoskeletal factors of the hip, lumbopelvic, abdominal, and pelvic floor regions and childbirth outcomes, as well as their…
- Conditions
- Pelvic Floor Disorders, Urinary Incontinence, Perineal Trauma, Pelvic Floor Dysfunction
- Trial name
- NCT07478159
- Testing
- Maternal Musculoskeletal Assessment
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Achilles Tendon Rupture
PATH-2: Platelet Rich Plasma in Achilles Tendon Healing
Platelet Rich Plasma in Achilles Tendon Healing Does using a Platelet Rich Plasma (PRP) injection immediately before standard casting benefit patients aged 18 or over who are suitable for nonsurgical treatment of the Achilles…
- Trial name
- PATH-2 (NCT02302664)
- Testing
- PRP Injection into Achilles tendon rupture gap, Imitation Injection into Achilles tendon rupture gap
- Where
- 18 sites in United Kingdom
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Spinal Cord Injury, Multiple Sclerosis
A Randomized Exercise Trial for Wheelchair Users
People with mobility disabilities are at greater risk than the general population for incurring health problems. Many of these conditions are preventable through behavior and lifestyle changes such as exercise and physical…
- Conditions
- Spinal Cord Injury, Multiple Sclerosis, Muscular Dystrophy, Cerebral Palsy
- Trial name
- NCT00866112
- Testing
- Educational session to promote physical activity, Minimal contact
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- University of Kansas
Partial Supraspinatus Tear, Rotator Cuff Tears (RCTs)
Platelet-Rich Plasma for Partial Rotator Cuff Tears
The goal of this clinical trial is to learn whether platelet-rich plasma (PRP) injection, made from a participant's own blood, can help heal the tendon and improve shoulder symptoms in people with partial tears of the…
- Conditions
- Partial Supraspinatus Tear, Rotator Cuff Tears (RCTs), Rotator Cuff Injury
- Trial name
- OPTIMISE (NCT07659600)
- Testing
- Platelet-Rich Plasma (PRP) Injections
- Volunteers
- 100 people
- Sponsor
- Universidade Nova de Lisboa
Muscle Injury, Muscle Soreness
Lemon Verbena Extract Oxidative Stress and Muscle Damage
In the present study, investigators investigated whether supplementation with lemon verbena extract (LVE) could improve muscle damage and biochemical indicators after exhaustive exercise challenge.
- Trial name
- NCT04742244
- Testing
- Lvemon verbena extract, maltodextrin
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Anterior Cruciate Ligament Injuries, Atrophy, Muscular
Bilateral Versus Unilateral Strength Training After ACLR
After rehabilitation completion, there remains large deficiencies between the operative (OP) and non-operative (NOP) limbs in lower-limb outcomes (e.g., size, strength, and function) and these deficits can persist for years.
- Conditions
- Anterior Cruciate Ligament Injuries, Atrophy, Muscular, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- BUST (NCT06032247)
- Testing
- Resistance exercise program- UL, Resistance exercise program- BL
- Where
- United States
- Sponsor
- University of Kansas
Osteoporotic Fractures
Effectiveness of Adipose Tissue Derived Mesenchymal Stem Cells as Osteogenic Component in Composite Grafts
Failure rates of up to 30% are reported after proximal humeral fractures despite angular-stable devices. This may devastate not only the functional outcome but also the independence of elderly patients.
- Trial name
- ROBUST (NCT01532076)
- Testing
- Cellularized composite graft augmentation, Acellular composite graft augmentation
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- University Hospital, Basel, Switzerland
Lateral Epicondylitis, Work Related Injury
Randomized Trial of Iontophoresis Versus Injection of Corticosteroids for Lateral Epicondylitis
The purpose of this project is to compare different treatment options for lateral epicondylitis. Lateral epicondylitis is a pain condition involving extensor muscles fo the forearm originating from the lateral epicondyle.
- Trial name
- NCT00257634
- Testing
- dexamethasone to injury site
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Henry Ford Health System