Clinical trials: Musculoskeletal Pain
Osteoarthritis, Arthritis, Rheumatoid
Low Dose Naltrexone for Chronic Pain in Osteoarthritis and Inflammatory Arthritis
Over 100 million Americans report chronic pain. One of the most common causes of chronic pain is osteoarthritis (OA). OA is attributable to "wear and tear," but reasons for pain are complex.
- Conditions
- Osteoarthritis, Arthritis, Rheumatoid, Arthritis, Psoriatic
- Trial name
- NCT04115020
- Testing
- Naltrexone
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Knee Osteoarthritis
Effect of Retro Walking Versus Isometric Multi-angular Exercises on Pain and Functional Performance in Knee Osteoarthritis in Geriatric Population
Osteoarthritis is a leading musculoskeletal cause of disability in elderly persons all over the world and a major cause of physical limitations and reduced quality of life (1).
- Trial name
- NCT06274346
- Testing
- Multiangular Isometric exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Delta University for Science and Technology
Cervical Spondylosis
Efficacy of Dynamic Exercise and Multi-angle Isometric Exercise in Cervical Spondylosis
Exercises are widely regarded as the primary approach for managing cervical spondylosis. Although several studies have examined the effectiveness of multi-angle isometric exercises and dynamic exercises in patients with cervical…
- Trial name
- NCT07048288
- Testing
- Multi-angle isometrics, Kinesio taping, Dynamic exercise
- Where
- India
- Volunteers
- 52 people
- Sponsor
- King Saud University
Temporomandibular Disorders (TMD), Myofascial Pain - Dysfunction Syndrome of TMJ
Adjunctive Acupuncture for Persistent Myofascial Temporomandibular Disorder Pain
Temporomandibular disorders (TMDs) can cause persistent pain in the jaw muscles and limitations in jaw function. Occlusal splints are commonly used to manage these symptoms, but some patients continue to experience pain despite…
- Trial name
- NCT07820488
- Testing
- Adjunctive Acupuncture
- Where
- Portugal
- Volunteers
- 30 people
- Sponsor
- Universidade do Porto
Chronic Disease
Integrative Therapy of Chronic Diseases
The observational study aims to investigate the extent to which a two-week stay in an internal medicine clinic for integrative medicine and naturopathy results in an improvement of complaints, impairments, quality of life…
- Trial name
- InteChron (NCT04927403)
- Testing
- multimodal integrative naturopathic therapy concept
- Where
- 3 sites in Germany
- Volunteers
- 1,000 people
- Sponsor
- Universität Duisburg-Essen
Myofascial Pain Syndrome
Effects of Thai Massage on EMG
The purpose of this study is to determine the effect of Thai massage on electromyogram in patients with chronic upper back pain associated with myofascial trigger points.
- Trial name
- NCT02067325
- Testing
- Thai massage
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Mae Fah Luang University Hospital
Fibromyalgia
The Effect of Digital Cognitive Behavioural Therapy for Insomnia on Physical Activity in Fibromyalgia
The goal of this clinical trial is to learn if a digital sleep therapy program (digital Cognitive Behavioural Therapy for Insomnia or dCBT-I) works to improve quality of life and movement in adults with fibromyalgia who also have…
- Trial name
- PainLESS-2 (NCT07465991)
- Testing
- Digital Cognitive Behavioural Therapy for Insomnia, Sleep Hygiene Education Materials
- Where
- 2 sites in United Kingdom
- Volunteers
- 142 people
- Sponsor
- University of Oxford
Knee Osteoarthritis
Exercise Therapy for Osteoarthritis Pain: How Does it Work?
International guidelines recommend exercise as the first choice treatment for knee osteoarthritis (KOA). Muscle strengthening training (MST) and behavioural graded activity (BGA) show comparable effects on KOA pain, but the…
- Trial name
- KOA-PAIN (NCT04362618)
- Testing
- Muscle Strengthening Training, Behavioral graded activity
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- Vrije Universiteit Brussel
Myofascial Trigger Point Pain
Manual Compression and Stretching for The Myofascial Trigger Points in Upper Trapezius and Levator Scapulae
To compare the effectiveness of manual compression and stretching for myofascial trigger points in upper trapezius and levator scapulae in male office workers
- Trial name
- NCT05873010
- Testing
- Manual Compression and Stretching
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Superior University
Cervical Radiculopathy, Cervical Spondylosis
Transcutaneous Auricular Vagus Nerve Stimulation Combined With Cervical Epidural Injection for Cervical Radiculopathy
This is a prospective, randomized, double-blinded, sham-controlled trial conducted to investigate the efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS) combined with cervical epidural injection in…
- Conditions
- Cervical Radiculopathy, Cervical Spondylosis, Radicular Pain
- Trial name
- NCT07557823
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Cervical Epidural Injection
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Fibromyalgia
Effect of Milnacipran on Pain Processing and Functional Magnetic Resonance Imaging (fMRI) Activation Patterns in Patients With Fibromyalgia
The purpose of this study is to evaluate the effect of milnacipran on how the brain processes pain in patients with fibromyalgia and to assess the relationship between this effect and brain activation patterns during functional…
- Trial name
- NCT00793520
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Forest Laboratories
Hyperglycemia, Hypercholesterolemia
Glucose Metabolism Disorders and Metabolic Syndrome Before and After Primary Hip and Knee Replacement
Osteoarthritis patients undergoing primary hip and knee replacement are followed-up and changes in their glucose metabolism and other metabolic parameters (obesity, cholesterol levels) are examined.
- Conditions
- Hyperglycemia, Hypercholesterolemia, Persistent Postoperative Pain, Hip Replacement
- Trial name
- HyTe-2 (NCT01743313)
- Where
- Finland
- Volunteers
- 155 people
- Sponsor
- Coxa, Hospital for Joint Replacement
Musculoskeletal Pain
Stretching and Musculoskeletal Pain
The purpose of this study is to assess whether a daily, 15-minute stretching routine for one year reduces musculoskeletal pain and improves quality of life in personnel working in the radiology and cardiology departments at Mayo…
- Trial name
- NCT04617379
- Testing
- Stretching
- Where
- 6 sites in United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hypophosphatemia, Hypophosphatemic Rickets
Open Label Trial Assessing Safety and Efficacy of Burosumab (KRN23), in a Patient With ENS and Hypophosphatemic Rickets
A 52 week, open label trial to assess the safety and efficacy of KRN23, an investigational antibody to FGF23, in a single pediatric patient with Epidermal Nevus Syndrome(ENS) and associated hypophosphatemic rickets A 26 weeks…
- Conditions
- Hypophosphatemia, Hypophosphatemic Rickets, Pain, Chronic
- Trial name
- NCT03581591
- Testing
- Burosumab
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Redwood Dermatology Sciences
Subacromial Impingement Syndrome, Subacromial Pain Syndrome
Copenhagen Cohort of Patients With Shoulder Pain
The COPAIN study is comprised of three studies; a cross-sectional study (study 1), a prospective study (study 2) and a randomized controlled trial (study 3).
- Conditions
- Subacromial Impingement Syndrome, Subacromial Pain Syndrome, Subacromial Impingement
- Trial name
- COPAIN (NCT05549674)
- Testing
- The COPAIN study is observational. There is no intervention.
- Where
- Denmark
- Volunteers
- 218 people
- Sponsor
- Hvidovre University Hospital
Rotator Cuff Tear or Rupture, Not Specified as Traumatic, Pain, Shoulder
Effectiveness of The Neuromuscular Control-Based Exercise Training in the Treatment of Partial-Thickness Rotator Cuff Tears
The aim of this study is to determine and compare the effects of neuromuscular control exercises for the shoulder, and standard conservative exercise programs, which are different forms of exercise and have an important role in…
- Trial name
- NCT05128474
- Testing
- Neuromuscular Control-Based Exercise Training Group, Conventional Exercise Training Group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Istanbul University - Cerrahpasa
Hip Pain Chronic, Femoro Acetabular Impingement
Education and Exercise for Patients With Longstanding Hip and Groin Pain
Longstanding hip and groin pain (LHGP) is a common and debilitating problem in young to middle aged individuals. These patients often get referred to orthopedic departments.
- Conditions
- Hip Pain Chronic, Femoro Acetabular Impingement, Groin Injury
- Trial name
- HIPSTER (NCT05853640)
- Testing
- Usual care, HIPSTER
- Where
- Sweden
- Volunteers
- 122 people
- Sponsor
- Lund University
Bursitis
Steroid Injection for the Treatment of Greater Trochanteric Pain Syndrome
The objective of this study is to conduct a randomized, single-blinded placebo controlled trial comparing two modalities for the treatment of pain and mobility associated with trochanteric bursitis: (1) injection of…
- Trial name
- NCT00863889
- Testing
- Depomedrol injection, Lidocaine, Marcaine
- Where
- United States
- Sponsor
- Emory University
Temporomandibular Joint Disorders
Nd-YAG Laser Versus Epidermal Growth Factor For Myogenic Tempromandibular Disorder.
A clinical trial comparing the potential effect of 2 different modalities (Nd-YAG Laser Versus Epidermal growth factor injection) on pain reduction in patients suffering from myogenic tempromandibular disorder.
- Trial name
- NCT06044974
- Testing
- Nd-YAG Fotona, Epidermal Growth Factor
- Where
- Egypt
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hallux Valgus, Surgery
Evaluation of the Efficacy of VR on Pain and Anxiety When Performing an Ultrasound-controlled Ankle Block.
The purpose of this study is to observe or not a reduction on pain and anxiety felt by the patient when performing an ultrasound-controlled ankle block in preparation for forefoot surgery, using a virtual reality device instead…
- Trial name
- VRBLOC (NCT03677323)
- Testing
- Virtual reality, Droleptan, Propofol
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Clinique Saint Jean, France