Clinical trials: Musculoskeletal Symptom
Muscle Weakness, Muscle; Fatigue, Heart
The Impact of Beef on Muscle Fatigue in Older Adults
The goal of this controlled-feeding cross-over diet intervention is to compare a beef diet to a vegetarian diet on muscle fatigue in older adults.
- Conditions
- Muscle Weakness, Muscle; Fatigue, Heart, Older Adults
- Trial name
- NCT05860088
- Testing
- Beef Diet, Vegetarian Diet
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Indiana University
Postoperative Pain, Shoulder Pain
Comparative Efficacy of Buprenorphine Transdermal Patch Versus Tramadol in Postoperative Analgesia for Shoulder Arthroscopy
This study compares the efficacy, safety, and patient satisfaction of the Buprenorphine 10 mg transdermal patch versus Tramadol for postoperative analgesia in shoulder arthroscopic surgery.
- Conditions
- Postoperative Pain, Shoulder Pain, Opioid Analgesia, Tramadol
- Trial name
- NCT06742554
- Testing
- Buprenorphine transdermal patch, Tramadol
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- medina medical center
Low Back Pain, Lumbar Spinal Stenosis
Improvement of Low Back Pain After Decompression in Patients with Degenerative Spinal Canal Stenosis
Degenerative lumbar spine disease is a leading cause of disability in the world; it encompasses conditions such as spondylolisthesis, disc degeneration, and lumbar spinal stenosis.
- Trial name
- NCT05791422
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Assiut University
Shoulder Pain, Rotator Cuff Impingement Syndrome
Bupivacaine or Radiofrequency for Shoulder Pain
Comparative study between pulsed radiofrequency in suprascapular nerve or bupivacaine block for chronic shoulder pain
- Conditions
- Shoulder Pain, Rotator Cuff Impingement Syndrome, Impingement Syndrome, Adhesive Capsulitis
- Trial name
- NCT05778422
- Testing
- Suprascapular nerve block with bipuvacaine, Pulsed radiofrequency
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Hip Osteoarthritis, Knee Osteoarthritis
Fit-Joints: Getting Fit for Hip or Knee Replacement
Osteoarthritis leads to reduced independence and quality of life. Total hip replacement is a successful and cost-effective surgical intervention to relieve pain and improve functioning in patients with osteoarthritis.
- Trial name
- Fit-Joints (NCT02885337)
- Testing
- Multi-Modal Frailty Intervention, Usual Care
- Where
- 2 sites in Canada
- Volunteers
- 41 people
- Sponsor
- McMaster University
Lumbar Disc Herniation, Pain, Postoperative
mTLIP vs. ITP Blocks in Lumbar Disc Surgery
to compare ultrasonography (USG)-guided intertransverse process block and modified thoracolumbar interfascial plan (mTLIP) block in the treatment of postoperative pain in patients undergoing lumbar disc herniation surgery under…
- Conditions
- Lumbar Disc Herniation, Pain, Postoperative, Regional Aneshesia
- Trial name
- NCT06391541
- Testing
- modified thoracolumbar interfacial plan block (mTLIP), Intertransverse process block (ITP)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Knee Osteoarthritis, Pain
Magnetotherapy Versus Microwave Combined With Exercise for Knee Osteoarthritis.
The high prevalence of knee osteoarthritis and the absence of well-defined protocols for the application of Magnetotherapy (MT), makes it necessary to investigate the effect of this therapy on patients with knee osteoarthritis.
- Trial name
- MT-MW-EX (NCT04866745)
- Testing
- Magnetotherapy plus exercise, Microwave plus exercise
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Castilla-La Mancha
Myasthenia Gravis
Exploring Outcomes and Characteristics of Myasthenia Gravis 2
The goal of this prospective observational study is to create a network repository of clinical data and biological samples to help researchers learn more about myasthenia gravis.
- Trial name
- EXPLORE-MG2 (NCT06002945)
- Testing
- Blood sample
- Where
- 10 sites in United States
- Volunteers
- 311 people
- Sponsor
- Yale University
Pain, Pain Intervention
Impact on Patients With Neuromuscular and Musculoskeletal Conditions Associated With Benign Chronic Pain Using Atlas Profilapxis
AtlasPROfilax®is a method performed in 2 authorized centers in Colombia focused on patients with chronic non-malignant pain. The study seeks to see the effectiveness of the method in different pathologies through a randomized…
- Trial name
- Atlasprofilax (NCT07745088)
- Testing
- Atlasprofilax Therapy
- Where
- Colombia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fundacion Nacional Somos
Urolithiasis, Renal Colic
Metabolic Workup in Patients Suffering From Kidney Stone Disease and Osteopenia
Patients suffering from acute renal colic are evaluated by non contrast computerized tomography with excellent identification rates of urinary stones.
- Conditions
- Urolithiasis, Renal Colic, Osteopenia
- Trial name
- NCT04080973
- Testing
- CT scan, 24 hour urine collection
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Ziv Hospital
Arthritis Shoulder, Rotator Cuff Injuries
Onlay Versus Inlay Humeral Component in Reverse Total Shoulder Arthroplasty
The goal of this study is to compare the effect of different ways to place the component that goes at the top of the humerus (upper arm) in reverse total shoulder replacement.
- Trial name
- NCT05297305
- Testing
- Tornier Ascend Flex stem, Tornier Perform Stem Reverse+
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Corewell Health East
Post-thoracotomy Pain Syndrome
IMPACT OF OPERATIVE POSITIONING ON THE DEVELOPMENT OF SHOULDER PAIN AFTER PULMONARY LOBECTOMY BY VATS
The investigators want to be able to show a 66% decrease in the incidence of shoulder pain in the "support" group compared to the "suspension" group.
- Trial name
- POVA (NCT04415242)
- Testing
- positioning
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Fibromyalgia, Pain, Chronic
Pain Severity in Fibromyalgia Syndrome
Fibromyalgia Syndrome (FMS) is a complex syndrome that mainly includes the musculoskeletal system and is characterized by many symptoms such as chronic widespread pain, fatigue and sleep disorders, cognitive dysfunctions…
- Trial name
- NCT05481086
- Testing
- No Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Kutahya Health Sciences University
Obesity, Bone Loss
The Effect of Gastric Bypass Surgery on Gut Hormones Related to Bone Remodeling and Intestinal Growth.
The overall purpose is to explore the link between the gut and the bones by investigating meal stimulated changes in the blood level of a number of hormones and markers related to intestinal growth and bone turnover in patients…
- Trial name
- NCT01700686
- Testing
- Meal test and dexa scan
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- University of Copenhagen
Lumbar Disc Herniation
Plane Block vs Intravenous Patient Controlled Analgesia
Acute postoperative pain begins with surgical trauma and decreases with tissue healing. Untreatable postoperative pain is one of the most important problems due to the increase in respiratory, cardiac and thromboembolic…
- Trial name
- NCT04457986
- Testing
- Erector spina plane block (ESP), Modified thoracolumbar interfacial plane block (MTI), Intravenous patient controlled analgesia (IV-PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Diskapi Teaching and Research Hospital
Fibromyalgia
Effects of Diatermy in Patients With Fibromyalgia.
Diathermy is a non-invasive pain therapy based on the local application of high-frequency electromagnetic waves. This procedure produces deep heat promotes tissue repair and influences pain sensitivity.
- Trial name
- FIBDIAT (NCT06414369)
- Testing
- Diathermy, Simulated Diathermy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Camilo Jose Cela University
Fibromyalgia, Central Neuropathic Pain
Nitrous Oxide as Treatment for Fibromyalgia
The purpose of this study is to explore a potential role of nitrous oxide in treating pain associated with fibromyalgia.
- Trial name
- NCT05357066
- Testing
- Nitrous oxide gas for inhalation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Musculoskeletal Pain
Topical CBD for Musculoskeletal Pain
Rationale: CBD is commonly being used as an over-the-counter treatment for musculoskeletal pain; however, no clinical trial has been performed to establish efficacy of CBD in humans for musculoskeletal pain.
- Trial name
- NCT05170451
- Testing
- CBD, Control
- Where
- United States
- Sponsor
- University of Virginia
Gout, Arthritis, Gouty
Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients (AR882-302)
This study will assess the serum uric acid lowering effect and safety of AR882 in gout patients at two doses compared to placebo over 12 months
- Conditions
- Gout, Arthritis, Gouty, Hyperuricemia, Gout Chronic
- Trial name
- NCT06439602
- Testing
- AR882 50 mg, AR882 75 mg
- Where
- 68 sites in United States, Australia and 3 more
- Volunteers
- 818 people
- Sponsor
- Arthrosi Therapeutics
Farber Disease, Farber's Disease
Farber Disease Natural History Study
The primary objective of this study is to establish the natural history of Farber disease (acid ceramidase deficiency) through the collection and analysis of retrospective and prospective data on patients diagnosed with Farber…
- Conditions
- Farber Disease, Farber's Disease, Farber Lipogranulomatosis, Acid Ceramidase Deficiency
- Trial name
- NCT03233841
- Where
- 15 sites in United States, Argentina and 7 more
- Volunteers
- 45 people
- Sponsor
- Sumitomo Pharma Switzerland GmbH
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