Clinical trials: Musculoskeletal Symptom
Osteoarthritis of Knee, Healthy Participants
Evaluation of Muscle Oxygenation and Recovery Dynamics in Individuals With Knee Osteoarthritis
Knee osteoarthritis (OA) is a degenerative joint disease characterized by pain, muscle weakness, and functional limitations that significantly affect lower limb muscle performance.
- Trial name
- NCT07471204
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Fibromyalgia (FM), Chronic Fatigue Syndrome (CFS)
Molecular Response to Custom Manual Physiotherapy Treatment of Fibromyalgia & Chronic Fatigue Syndrome (CFS)
Fibromyalgia (FM)and Chronic Fatigue Syndrome (CFS) are complex diseases often presenting overlapping symptomatology. Manual therapy (MT) protocols report benefits for pain treatment of FM, but the underlying mechanisms for…
- Trial name
- NCT04174300
- Testing
- Manual Therapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Multiple Sclerosis, Spasticity
One Year, Open Label, Dose Escalation Long-term Safety Study in Multiple Sclerosis (MS) Subjects With Spasticity
Clinical protocol OS440-3003 is a multicenter, open-label, non-randomized, uncontrolled, dose escalation study to evaluate the safety and tolerability of Arbaclofen Extended Release Tablets over 1 year in Multiple Sclerosis (MS)…
- Trial name
- NCT01844232
- Testing
- arbaclofen
- Where
- 35 sites in United States, Russia and 1 more
- Volunteers
- 150 people
- Sponsor
- RVL Pharmaceuticals, Inc.
Shoulder Pain, Postoperative Pain
The Analgesic Effect of (SHAC) Block Versus Suprascapular Nerve Block in Arthroscopic Shoulder Surgeries
The aim of the study is to compare the post-operative analgesic effect of Shoulder anterior capsule (SHAC) block with Suprascapular nerve block for arthroscopic shoulder surgery with a hypothesis that both Shoulder anterior…
- Trial name
- NCT06529393
- Testing
- SHAC block, suprascapular nerve block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Knee Osteoarthritis, Postoperative Pain
Ultrasound-Guided PASC Block vs Femoral-Sciatic Nerve Block for Postoperative Analgesia After Total Knee Arthroplasty
This randomized, double-blind comparative study evaluates postoperative analgesic efficacy and motor effects of ultrasound-guided para-sartorial compartments (PASC) block versus ultrasound-guided combined femoral-sciatic nerve…
- Conditions
- Knee Osteoarthritis, Postoperative Pain, Total Knee Arthroplasty
- Trial name
- NCT07320833
- Testing
- Ultrasound-Guided Femoral Nerve Block plus Sciatic Nerve Block, Ultrasound-Guided Para-sartorial Compartments Block
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Ain Shams University
Hemifacial Microsomia, Mucormycosis
Clinical Evaluation of Patient-Specific 3D-Printed Titanium Implants for Facial Reconstruction.
This clinical study aims to evaluate the effectiveness of patient-specific 3D-printed titanium facial implants in the reconstruction and aesthetic correction of facial defects.
- Conditions
- Hemifacial Microsomia, Mucormycosis, Oral Squamous Cell Carcinoma, Microgenia
- Trial name
- 3DFACE (NCT07654647)
- Testing
- Patient-specific titanium implants for facial reconstruction
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Latakia University
Old Age; Debility, Muscle Weakness
Probiotic-Muscle Study
This study will examine the effect of probiotic supplementation (Bacillus coagulans) on muscle protein synthesis in older adults in response to a plant-based diet.
- Conditions
- Old Age; Debility, Muscle Weakness, Protein Deregulation, Protein Deposition
- Trial name
- NCT04297111
- Testing
- Probiotic
- Where
- Ireland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Breast Cancer, Arthralgia
Observational Study to Evaluate Mechanisms of Aromatase Inhibitor Associated Musculoskeletal Symptoms
Early stage hormone receptor positive breast cancer is typically treated with adjuvant endocrine therapy in order to decrease risk of breast cancer recurrence and to improve overall survival from the disease.
- Trial name
- NCT02118636
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Lynn Henry
Myofascial Pain Syndrome of Neck, Trigger Point Pain, Myofascial
Effects of Pressure Release of Myofascial Trigger Points on Mechanical Neck Pain.
The study aims to compare the effectiveness of myofascial trigger point treatment using pressure release versus a control group in patients with mechanical neck pain, randomly assigned.
- Conditions
- Myofascial Pain Syndrome of Neck, Trigger Point Pain, Myofascial, Myofacial Pain
- Trial name
- NCT06051799
- Testing
- Myofascial trigger points pressure release, Therapeutic exercise and postural hygiene
- Where
- Spain
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Shoulder Surgery, Shoulder Pain
Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block
This prospective observational study aims to evaluate the incidence of hemidiaphragmatic paralysis in patients receiving interscalene brachial plexus nerve block with prolonged neural blockade.
- Conditions
- Shoulder Surgery, Shoulder Pain, Shoulder Injuries, Shoulder Arthritis
- Trial name
- NCT04209504
- Testing
- Ultrasound, Ropivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Chronic Pain, Musculoskeletal Pain
Feasibility of At-Home Telehealth Yoga for Treating Chronic Pain
This feasibility study will evaluate yoga as a treatment for chronic musculoskeletal pain. The experimental treatment is yoga delivered via a tablet computer to participants at home ("teleyoga").
- Trial name
- NCT04074109
- Testing
- Teleyoga, In-person yoga
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Palo Alto Veterans Institute for Research
Leg Length Inequality
Reliability of Clinical Limb-length Measurements Methods
There are numerous ways to measure limb length discrepancy in the clinical practice, although their reliability and accuracy are not well known.
- Trial name
- NCT05122533
- Testing
- EOS, Clinical limb length measurements
- Where
- Hungary
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Chronic Neuropathic Pain and Fibromyalgia
Ambulatory Infusions of Lidocaine and Ketamine for Management of Chronic Pain
As lidocaine and ketamine provide analgesia by acting on different molecular pathways, administering them together may produce synergistic effects, which can allow for using a lower dose of each medication and thereby reducing…
- Trial name
- NCT04123652
- Testing
- Lidocaine Hydrochloride 2% Intravenous Solution, DIN 02421992
- Where
- Canada
- Volunteers
- 162 people
- Sponsor
- Allevio Pain Management Clinic
Peripheral Arterial Disease
Mechanisms That Produce the Leg Dysfunction of Claudication & Treatment Strategies
Intermittent claudication afflicts 5% of the US population older than 55 years of age and develops along with hardening of the arteries of the legs.
- Trial name
- NCT01970332
- Testing
- Revascularization Surgery, Supervised exercise therapy
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Nebraska
HIV, Osteoporosis
Fracture and Bone Mineral Density in HIV+ Patients Recently Started on Antiretroviral Therapy (ART)
In a group of HIV-positive patients under observation since their first exposure to ART or monitored off of ART, BMD changes over one year will be determined.
- Trial name
- NCT01591252
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Alabama at Birmingham
Peripheral Nerve Disease, Muscular Injury
Innervation Characteristics and Determination of Nerve Entry Points of the Musculus Semispinalis Capitis
The aim of this study is to determine the innervation characteristics and nerve entry points of the musculus semispinalis capitis.
- Trial name
- NCT06569563
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Medipol University
NMO Spectrum Disorder, Spasticity, Muscle
A Phase IIb Study of Nabiximols for Spasticity Due to Neuromyelitis Optica Spectrum Disorders
The goal of this clinical trial is to evaluate the safety and efficacy of nabiximols, a cannabinoid spray, for the treatment of moderate to severe spasticity in adult patients with AQP4-IgG positive and antibody-negative NMOSD.
- Trial name
- SENS-NMO (NCT05974293)
- Testing
- Nabiximols
- Where
- United States
- Sponsor
- Michael, Levy M.D.,Ph.D.
Stroke, Spastic Hemiplegia
Effects of Neuromuscular Electrical Stimulation on Flexor Spasticity and Function in Stroke Patients
In this study, the investigators aimed to determine the effects of botulinum neurotoxin type A injections for wrist and finger flexor spasticity and neuromuscular electrical stimulation therapy applied to wrist and finger flexors…
- Trial name
- NCT06725069
- Testing
- Neuromuscular Electrical Stimulation, Control (Standard treatment)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Chronic Pain, Musculoskeletal Pain
Posturographic Characteristics of Eccentric, Isometric and Concentric Movements
Determine the posturographic characteristics of eccentric, isometric and concentric movements in healthy subjects as well as in subjects with chronic, orthopedic conditions / pain not involving the lower extremities.
- Trial name
- NCT02577653
- Testing
- Posturographic evaluation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Carrick Institute for Graduate Studies
Duchenne Muscular Dystrophy, Lower Urinary Tract Symptoms
Examination of Lower Urinary System Symptoms With Duchenne Muscular Dystrophy
The aim of this study is to examine the prevalence of lower urinary tract symptoms (LUTS) in children with Duchenne Muscular Dystrophy (DMD) and the relationship between functional level, posture, muscle strength, pelvic floor…
- Conditions
- Duchenne Muscular Dystrophy, Lower Urinary Tract Symptoms, Muscle Weakness, Posture Disorders in Children
- Trial name
- NCT05464446
- Testing
- Baseline Bubble Inclinometer, Baseline Digital İnclinometer and Hoggan microFET2 devices
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Lokman Hekim University
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