Clinical trials: Musculoskeletal Symptom
Postoperative Recovery, Lumbar Disc Herniation
Lower Back Muscle Size and Recovery After Lumbar Disc Herniation Surgery
Recovery after surgery for a herniated disc in the lower back differs from person to person. The size of the muscles around the lower spine may be related to recovery, but this relationship is not well understood.
- Trial name
- NCT07768241
- Testing
- Preoperative Psoas and Multifidus Muscle Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Fibromyalgia
Tailored Treatments of Fibromyalgia
This study will evaluate the effects of matching treatments to people with fibromyalgia syndrome (FMS) on the basis of their psychosocial and behavioral characteristics.
- Trial name
- NCT00000422
- Testing
- Cognitive-behavioral psychotherapy and physical exercise
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- University of Washington
Cerebral Palsy
Effects of Dynamic Flex Cast With Neurodevelopmental Treatment on Gross Motor Functions in Cerebral Palsy
The study aims to determine the effects of dynamic flex cast with neurodevelopmental treatment on gross motor functions and gait in children with cerebral palsy.
- Trial name
- NCT05751122
- Testing
- Dynamic flex cast with neurodevelopmental treatment, Rigid Ankle foot Orthosis with neurodevelopmental treatment
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Chronic Fatigue Syndrome, Fibromyalgia
Proteomics of Cerebrospinal Fluid in Chronic Fatigue Syndrome
The purpose of this study is: 1. To identify specific set of proteins in the cerebrospinal fluid (fluid surrounding the brain and the spinal cord), that are believed to be seen in Chronic fatigue syndrome (CFS) patients, but not…
- Conditions
- Chronic Fatigue Syndrome, Fibromyalgia, Gulf War Illness, Multiple Chemical Sensitivity
- Trial name
- NCT00810329
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Fatigue Syndrome, Chronic, Epstein-Barr Virus Infection
Mental Training for CFS Following EBV Infection in Adolescents
The general aim of this study is to investigate the effect of an individually tailored mental training program in adolescents developing chronic fatigue syndrome (CFS) after an acute Epstein Barr-virus (EBV) infection.
- Trial name
- NCT02499302
- Testing
- Mental training
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital, Akershus
Hip Osteoarthritis, Hip Arthroplasty Replacement
Virtual Reality for Intraoperative Anxiolysis and Postoperative Agitation in Elderely Hip Arthroplasty Patients
This study evaluates the effectiveness of Virtual Reality (VR) as a non-pharmacological intervention to reduce intraoperative anxiety and postoperative agitation in elderly patients undergoing elective hip arthroplasty under…
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Emergence Delirium, Anesthesia, Emergence Agitation
- Trial name
- VR (NCT07705451)
- Testing
- immersive virtual reality, standard sedation
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Autoimmune Pancytopenia, Autoimmune Lymphoproliferative Syndrome (ALPS)
Sirolimus for Autoimmune Disease of Blood Cells
Treatment for patients with autoimmune destruction of blood cells is poor. The part of the body that fights infections is called the immune system and white blood cells (WBCs) are part of the immune system.
- Conditions
- Autoimmune Pancytopenia, Autoimmune Lymphoproliferative Syndrome (ALPS), Evans Syndrome, Idiopathic Thrombocytopenic Purpura
- Trial name
- NCT00392951
- Testing
- sirolimus
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital of Philadelphia
Physical Activity, Muscle Recovery
Effect of NMN on Muscle Recovery and Physical Capacity in Healthy Volunteers With Moderate Physical Activity
The purpose of this study is to evaluate the effect of NMN supplementation (250 and 500 mg/day over 38 days) compared to placebo in healthy volunteers with moderate physical activity on muscle recovery, physical capacity…
- Trial name
- NCT04664361
- Testing
- Nicotinamide mononucleotide
- Where
- France
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Seneque SA
Chronic Fatigue Syndrome
Therapy for Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder
The purpose of this study is to determine whether therapy that has been shown to be beneficial for mitochondrial diseases is also beneficial for Chronic Fatigue Syndrome (CFS) patients.
- Trial name
- NCT01872351
- Testing
- Nutraceuticals
- Where
- United States
- Sponsor
- Columbia University
Temporomandibular Disorders (TMD), Functional Limitation
Functionality and Clinical Correlates in TMD
Temporomandibular disorders (TMD) are among the most common causes of orofacial pain and refer to structural and functional impairments related to the masticatory muscles, surrounding soft tissues, and/or the temporomandibular…
- Conditions
- Temporomandibular Disorders (TMD), Functional Limitation, Pain Severity, Neck Disability
- Trial name
- NCT06937502
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istinye University
Arthritis, Arthritis, Juvenile Idiopathic
Pain in Inflammatory Joint Diseases
Our primary objective is to better understand the etiology and consequences of chronic paint by using an explorative approach to identify phenotypes and endotypes of patients with inflammatory joint diseases, with a special focus…
- Conditions
- Arthritis, Arthritis, Juvenile Idiopathic, Arthritis,Rheumatoid, Arthritis, Reactive
- Trial name
- Nor-Pain (NCT06718569)
- Testing
- Biological or targeted synthetic DMARD
- Where
- Norway
- Volunteers
- 350 people
- Sponsor
- Diakonhjemmet Hospital
Muscle Spasticity, Cerebral Palsy
Radial Extracorporeal Shock Wave Therapy for Spastic Plantar Flexor Muscles in Young Children With Cerebral Palsy
The purpose of this study is to determine whether radial extracorporeal shock wave therapy in combination with traditional physical therapy is safe and effective for the management of spastic plantar flexor muscles in patients…
- Trial name
- NCT02719483
- Testing
- Swiss DolorClast, Traditional conservative therapy
- Volunteers
- 66 people
- Sponsor
- The First Hospital of Jilin University
Inflammation, Rheumatoid Arthritis
A Randomised, Double-blind, Placebo-controlled, Parallel-group Trial to Assess Clinical Efficacy of NNC0114-0006 in Subjects With Active Rheumatoid Arthritis
This trial is conducted in Europe. The aim of the trial is to evaluate the change in disease activity following intravenous (i.v.) administration of two doses of NNC0114-0006 compared to placebo in subjects with active rheumatoid…
- Trial name
- NCT01647451
- Testing
- NNC0114-0006
- Where
- 33 sites in Bulgaria, Hungary and 5 more
- Volunteers
- 62 people
- Sponsor
- Novo Nordisk A/S
Cerebral Palsy
Pully System Exercise Role in Management of Spasticity
The goal of this clinical trial is to investigate the effect of pully system exercise in in management of spasticity in cerebral palsy children Does pully system exercise has role in management of spasticity in cerebral palsy…
- Trial name
- NCT06927869
- Testing
- designed physical therapy , pully system exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kafrelsheikh University
Rheumatoid Arthritis
SonoElastography of Median Nerve in Rheumatoid Arthritis
To assess the role of ultrasonography and SE in detecting the median nerve changes before progression to CTS in patients with RA.
- Trial name
- NCT06135129
- Testing
- Sonoelastography
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Assiut University
Temporomandibular Disorder
Effect of Massage Therapy and Occlusal Splint Therapy on the Electromyographic Activity and Mandibular Range of Motion in Individuals With Temporomandibular Disorder
The objectives of this study were to investigate the effects of massage therapy and occlusal splint therapy in the electromyographic activity and mandibular range of motion (ROM) in individuals with temporomandibular disorder…
- Trial name
- NCT01874041
- Testing
- Massage, Occlusal splint
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Spasticity
Study of Intramuscular Injections of OnabotulinumtoxinA to Assess Change in Disease Activity in Pediatric Participants With Spasticity Associated With Cerebral Palsy
Spasticity is often observed as muscle tightness and stiffness in the upper and/or lower limbs. Upper limb spasticity can interfere with joint movement and its severity can range from mild to severe.
- Trial name
- NCT06150729
- Where
- 8 sites in Mexico
- Volunteers
- 107 people
- Sponsor
- AbbVie
Psoriatic Arthritis, Osteoarthitis
CARTIZ Registry: Cartilage, Arthropathy and Imaging Under Tirzepatide in Zone-stratified Cohorts - A Four-Institute Mexican Observational Registry
CARTIZ is a prospective observational clinical registry of adults in Mexico receiving tirzepatide (a dual GLP-1/GIP receptor agonist) under an independent clinical indication - typically type 2 diabetes, insulin resistance…
- Conditions
- Psoriatic Arthritis, Osteoarthitis, Knee, Diabetes (DM)
- Trial name
- CARTIZ (NCT07567378)
- Testing
- Tirzepatide
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- JULIO GRANADOS MONTIEL
Chronic Pain
VR for Patients With Chronic Pain (Wait & Work)
This cluster-RCT evaluates the effect of therapeutic virtual reality (VR) on patients with chronic musculoskeletal pain (CMP) who are on a waiting list to receive pain treatment.
- Trial name
- NCT06312735
- Testing
- VR (Reducept)
- Where
- 4 sites in Netherlands
- Volunteers
- 53 people
- Sponsor
- University of Twente
Degenerative Scoliosis
The Adult Degenerative Scoliosis Exercise Trial (Pilot Study)
Adult degenerative scoliosis is the most common spine deformity in adults. Patients present a lateral curvature of the spine and vertebra rotation.
- Trial name
- ADSET (NCT03862417)
- Testing
- Schroth exercises
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
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