Clinical trials: Musculoskeletal Symptom
Ischemic Brain
Immediate Effect of Laser on Spasticity
The poor eating habits and sedentary lifestyle of young people can reflect on structural changes in adult life, leading to vascular brain diseases.
- Trial name
- NCT02014935
- Testing
- Low intensity laser
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Laboratório de Engenharia de Reabilitação Sensorio Motora
Arthritis, Arthralgia
Immune-Mediated Pathophysiology And Clinical Triage Program
Many people develop joint pain, stiffness and swelling due to their cancer treatment that targets the immune system. The severity of symptoms ranges from mild to debilitating and sometimes requires delaying or stopping cancer…
- Trial name
- IMPACT 2 (NCT04354649)
- Testing
- Hydroxychloroquine
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- AHS Cancer Control Alberta
Fatigue, Juvenile Idiopathic Arthritis
Fatigue and Sleep in Children and Adolescents With Juvenile Idiopathic Arthritis: A Cross-Sectional Study
The aims of this study is to primarily investigate fatigue and sleep and to secondarily examine possible relationships between disease activity, pain and functional ability in Turkish children and adolescents with Juvenile…
- Trial name
- NCT03618680
- Volunteers
- 96 people
- Sponsor
- Istanbul University
Chronic Conditions, Multiple, Diseases of the Circulatory System
National Institute for Health and Care Research Global Health Research Centre for Multiple Long-Term Conditions
Multiple Long-Term Conditions (MLTC), defined as the coexistence of two or more chronic conditions, is increasingly prevalent in India.
- Conditions
- Chronic Conditions, Multiple, Diseases of the Circulatory System, Diseases of the Respiratory System, Endocrine, Nutritional and Metabolic Diseases
- Trial name
- NIHR-GHRC MLTC (NCT07582380)
- Testing
- Electronic Decision Support System (EDSS), Assisted Telemedicine, Patient-facing app for self-management, supported by care coordination through Community Champions and Care Coordinators.
- Where
- 120 sites in India, Nepal
- Volunteers
- 3,600 people
- Sponsor
- Centre for Chronic Disease Control, India
Osteoarthritis, Peripheral
Innovative Device for Pain Management by Millimeter Band Radiation : Electronic-Pain Killer.
In this study, in addition of conventional treatment, the efficacy of the medical device, Remedee One, in medical care of patients with peripheral osteoarthritis pain is evaluated.
- Conditions
- Osteoarthritis, Peripheral, Pain
- Trial name
- Epikarthrose (NCT04590079)
- Testing
- Conventional pain treatment with daily sessions with innovative medical device, Remedee One, for pain management by Millimeter Band Radiation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Inflammation, Oxidative Stress
Antioxidants Combined With Cryotherapy on Inflammatory Response After Resistance Exercise in Untrained Volunteers
Acutely resistance exercise induces inflammatory responses and leukocytosis arising of oxidative stress, that clinically manifested by pain and/or delayed onset muscle soreness (DOMS).
- Conditions
- Inflammation, Oxidative Stress, Pain
- Trial name
- NCT02902315
- Testing
- Cryotherapy, Vitamins C and E, Vitamins C and E associated with cryotherapy
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Depressive Disorder, Fatigue Syndrome, Chronic
Glucocorticoid Effects on Cellular Cytokine Release
A variety of hormones and immune system processes are responsible for how the body responds to illness. This study concentrates on how the hormone cortisol effects the release of immune system factors called cytokines.
- Conditions
- Depressive Disorder, Fatigue Syndrome, Chronic, Fibromyalgia, Healthy
- Trial name
- NCT00001415
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Back Pain, Neck Pain
Cross-Disciplinary Workplace Intervention Strategy for Chronic Musculoskeletal Disorders
Sickness absenteeism caused by MSDs is a persistent and expensive health challenge in all industrial countries including Switzerland.
- Conditions
- Back Pain, Neck Pain, Musculoskeletal Abnormalities
- Trial name
- NCT00369135
- Testing
- combined intervention
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Institut Universitaire Romand de Sante au Travail
Osteonecrosis of the Jaw, Bisphosphonate Induced, Osteonecrosis of the Jaw, Bisphosphonate Related
Initial Management of MRONJ Stages I and II, a Clinical Trial With Detection of Salivary Biomarkers
Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication in patients receiving antiresorptive therapies, such as Bisphosphonates and Denosumab.
- Trial name
- NCT04584840
- Testing
- Surgical treatment
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Weakness, Muscle, Muscle Tightness
Pilates Exercises v/s Yoga on Rounded Shoulders
To Compare the effects of Pilates exercises an yoga on rounded shoulders
- Conditions
- Weakness, Muscle, Muscle Tightness, Range of Motion, Pain
- Trial name
- NCT05876650
- Testing
- Pilates exercises, Yoga
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pelvic Girdle Pain
Effects of Muscle Energy Techniques Versus Core Stability Exercises in Pelvic Girdle Pain
PGP is referred to as a specific form of LBP which occurs isolatedly as well as in combination with lumbar back pain. PGP localized to the anterior or posterior pelvis, most commonly located between the posterior iliac crest and…
- Trial name
- NCT05787158
- Testing
- Muscle energy techniques
- Where
- Pakistan
- Volunteers
- 57 people
- Sponsor
- Riphah International University
Shoulder Pain, Shoulder Impingement Syndrome
Performance and Safety of LightForce® Therapy Lasers on Shoulder Soft Tissue Inflammation Pain Reduction
DJO UK Ltd (ENOVIS) is conducting this study to assess the effectiveness of LightForce® Therapy Lasers on pain reduction in shoulder soft tissue inflammation.
- Conditions
- Shoulder Pain, Shoulder Impingement Syndrome, Rotator Cuff Tendinitis
- Trial name
- SHINE (NCT06759935)
- Testing
- Laser therapy, physiotherapy/exercise protocol
- Where
- 10 sites in France, Italy and 1 more
- Volunteers
- 104 people
- Sponsor
- DJO UK Ltd
Sjögren Syndrome
Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjogren's Syndrome
This study was to evaluate the safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of multiple doses of CFZ533 (iscalimab) in patients with Sjögren's Syndrome (SjS).
- Trial name
- TWINSS (NCT03905525)
- Testing
- CFZ533
- Where
- 71 sites in United States, Argentina and 21 more
- Volunteers
- 273 people
- Sponsor
- Novartis Pharmaceuticals
Osteoarthritis, Arthritis
Efficacy And Safety Study Of Tanezumab Subcutaneous Administration In Osteoarthritis - A Subcutaneous/Intravenous Bridging Study
This is an efficacy and safety study of 3 doses (2.5 mg, 5 mg and 10mg) of tanezumab administered subcutaneously versus placebo.
- Conditions
- Osteoarthritis, Arthritis, Pain
- Trial name
- NCT01089725
- Testing
- Tanezumab SC, Tanezumab IV
- Where
- 91 sites in United States
- Volunteers
- 385 people
- Sponsor
- Pfizer
Stroke
TENS Effect on Gait and QoL in Stroke.
A study was conducted to investigate the additional effect of TENS applied to acupuncture points to the physical therapy program on gait and quality of life in stroke patients.
- Trial name
- NCT06673940
- Testing
- Transcutaneous electrical nerve stimulation (TENS), Physical Therapy program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Fibromyalgia, Sleep Disorders
Effects Of Pregabalin (Lyrica) On Sleep Maintenance In Subjects With Fibromyalgia
The purpose of the study is to demonstrate the effect of Lyrica on Wake after sleep onset in subjects with fibromyalgia with sleep maintenance disturbance (on polysomnogram)
- Trial name
- NCT00883740
- Testing
- Pregabalin
- Where
- 50 sites in United States, Canada and 1 more
- Volunteers
- 119 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Adhesive Capsulitis
Comparison of Capsular Stretching and Passive Joint Mobilization in Idiopathic Adhesive Capsulitis
The aim of this research is to determine the effects of capsular stretching versus passive joint mobilization on Pain, range of motion and Quality of life in patients with Idiopathic Adhesive capsulitis.
- Trial name
- NCT05903768
- Testing
- Mobilization, Cyriax capsular stretching
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Primary Osteoarthritis, Post-traumatic Osteoarthritis of Hip Nos
Observational Study Evaluating Outcomes of Hip Arthroplasty Using Tornier Dual Mobility Acetabular Cup
The purpose of this study is to demonstrate the performance and reliability of Tornier "Dual Mobility Cup" used during primary total hip replacement or hip replacement revision surgery at least 24 months post-insertion.
- Conditions
- Primary Osteoarthritis, Post-traumatic Osteoarthritis of Hip Nos, Femur Head Necrosis, Femur Neck Fracture
- Trial name
- NCT02062450
- Testing
- Primary surgery with Dual Mobility Cup, Revision surgery with Dual Mobility Cup
- Volunteers
- 379 people
- Sponsor
- Stryker Trauma and Extremities
Pelvic Girdle Pain
Comparing Effects of Kinesio and Dynamic Tapings in Postpartum Women With Pelvic Girdle Pain
About 45% of pregnant women and 25% of women postpartum suffer from Pelvic girdle pain. Pain is often reported to be localized between costal margin and gluteal fold with or without radiation to lower limb or symphysis pubic.
- Trial name
- NCT04873778
- Testing
- Kinesio taping, Dynamic taping
- Where
- Taiwan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Stroke Gait Rehabilitation
The Effect of Whole-Body Vibration Therapy Following Botulinum Toxin A Injection on Spasticity and Balance in Stroke Patients
The purpose of this clinical study is to evaluate the effect of Whole Body Vibration (WBV) therapy, applied two weeks after botulinum toxin type A (BoNT-A) injection, on spasticity and balance parameters in individuals with…
- Trial name
- NCT07286435
- Testing
- Whole body vibration therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Uludag University
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