Clinical trials: Musculoskeletal Symptom
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
28mm Ceramic-on-Ceramic Total Hip Replacement Study
This study is intended to gather medium (0-5 years) and long-term (6-10 years) information regarding the performance and safety of the commercially available Ceramax™ Ceramic on Ceramic Total Hip System.
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-traumatic Arthritis
- Trial name
- COC28 (NCT01657435)
- Testing
- Ceramax Acetabular System
- Where
- 13 sites in United States, Canada
- Volunteers
- 185 people
- Sponsor
- DePuy Orthopaedics
Labrum Injury of the Hip Joint, Hip Arthroscopy
Absorbable vs Non-Absorbable Sutures for Hip Capsular Closure
The study is to prospectively compare absorbable sutures with non-absorbable sutures used for capsular repair during hip arthroscopic procedures.
- Conditions
- Labrum Injury of the Hip Joint, Hip Arthroscopy, Femoroacetabular Impingement Syndrome
- Trial name
- NCT06845735
- Testing
- Non-Absorbable Sutures, Absorbable Suture
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Missouri-Columbia
Occupational Health, Posture
Experiential Learning vs Traditional Ergonomic Training in Logistics Workers
Background: Musculoskeletal disorders are common occupational health problems among industrial workers, particularly manual material handlers involved in repetitive lifting and physical tasks.
- Conditions
- Occupational Health, Posture, Work Related Musculoskeletal Disorders
- Trial name
- NCT07745400
- Testing
- Experiential Learning-Based Ergonomic Training Program, Traditional Ergonomic Seminar Education
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Okan University
Tennis Elbow Syndrome, Golfer's Elbow
Effects of Peripheral Repetitive Peripheral Magnetic Stimulation on Individuals With Elbow or Wrist Chronic Pain
This pilot, randomized, sham-controlled, single-blind study will evaluate the effectiveness of repetitive peripheral magnetic stimulation (rPMS) in reducing pain in adults with tennis/golfer's elbow or carpal tunnel syndrome.
- Conditions
- Tennis Elbow Syndrome, Golfer's Elbow, Carpal Tunnel Syndrome (CTS)
- Trial name
- rPMS (NCT07544914)
- Testing
- Two days Active rPMS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Neuropathic Pain
Neuropathic Pain Symptoms in Arthritis
It was aimed to compare neuropathic pain symptoms in hand osteoarthritis and rheumatoid arthritis.
- Trial name
- NCT05975281
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Inflammatory Arthritis, Rheumatoid Arthritis
The CCP Study: Coordinated Programme to Prevent Arthritis - Can We Identify Arthritis at a Pre-clinical Stage ?
This is a 12-month, prospective, observational cohort trial involving Primary Care Trusts (PCTs) wishing to take part in the study and the Early Arthritis Clinic (Anti-CCP sub-clinic) at Chapel Allerton Hospital.
- Trial name
- CCP (NCT02012764)
- Where
- United Kingdom
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Chronic Pain
Low Level Laser Therapy With Physical Therapy for Chronic Musculoskeletal Pain
1. Examine the use of low level therapeutic laser (LLLT) combined with physical therapy for improvements in pain, range of motion, and function in individuals with chronic pain from musculoskeletal conditions. 2.
- Trial name
- NCT02785432
- Testing
- Active low level laser
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Texas Southwestern Medical Center
Pain, Postoperative, Developmental Dysplasia of the Hip
Postoperative Analgesic Effect of Two Peripheral Nerve Blocks for Hip Surgery in Pediatrics
Hip joint surgery for developmental dysplasia of the hip (DDH) in children is extremely painful and associated with considerable postoperative pain despite the use of systemic opioids.
- Conditions
- Pain, Postoperative, Developmental Dysplasia of the Hip, Regional Anesthesia Morbidity
- Trial name
- NCT05348421
- Testing
- FTPB, PENG Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Breast Cancer
Clinical Trial Evaluating the Efficacy and Implementation of an Early Adapted Physical Activity to Prevent and Manage Aromatase Inhibitor-induced Musculoskeletal Pain in Breast Cancer (APIS)
Aromatase inhibitors (AI) are the standard adjuvant hormone therapy for postmenopausal women with hormone-sensitive breast cancer.
- Trial name
- APIS (NCT07295457)
- Testing
- Adapted Physical Activity started early, Adapted Physical Activity begins at the start of hormone therapy
- Where
- 2 sites in France
- Volunteers
- 182 people
- Sponsor
- Hospices Civils de Lyon
Osteoarthritis
Buprenorphine Transdermal Patches (BTDS) in Subjects With Osteoarthritis Pain. Includes a 52-week Extension Phase.
The original objective of this study was to demonstrate the effectiveness and tolerability of the buprenorphine transdermal system (BTDS) 20 micrograms (mcg)/hour (h) in comparison to the buprenorphine transdermal system 5 mcg/h…
- Trial name
- NCT00320801
- Testing
- Buprenorphine transdermal patch
- Where
- 66 sites in United States
- Volunteers
- 188 people
- Sponsor
- Purdue Pharma LP
Osteoarthritis, Avascular Necrosis
Cormet Post-PMA Study: New Enrollment
The primary objective of this study is to evaluate the performance of the Cormet Hip Resurfacing implant system in the post-approval environment.
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis
- Trial name
- PASNew (NCT00722007)
- Testing
- Cormet Hip Resurfacing
- Where
- 6 sites in United States
- Volunteers
- 147 people
- Sponsor
- Corin
Knee Osteoarthritis, Older Women
Adding Group-Based Pain Neuroscience Education to a Community Exercise Program for Older Women With Knee Osteoarthritis
This pilot trial aimed to estimate preliminary clinical effects and to assess the feasibility of adding group-based pain neuroscience education (PNE) to exercise in women aged ≥60 years with medically diagnosed knee…
- Conditions
- Knee Osteoarthritis, Older Women, Pain, Disability
- Trial name
- NCT07565298
- Testing
- Pain neuroscience education (PNE), Exercise program
- Where
- Chile
- Volunteers
- 19 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Osteo Arthritis of the Knee
Research Title: Long Term Functional Outcome of a Single Hyaluronic Acid Injection in Improving Symptoms and Function in Patients With Knee Osteoarthritis - A Single-Arm Open-Label Study (DIART ONE).
This study aims to evaluate the effectiveness of a single HA injection in improving pain, function, and quality of life in patients with knee OA over a 12-month period.
- Trial name
- NCT07736781
- Testing
- Hyaluronic Acid (HA)
- Where
- Malaysia
- Volunteers
- 62 people
- Sponsor
- Universiti Sains Malaysia
Psoriatic Arthritis, Psoriasis
Pain Mechanisms and Ultrasonographic Disease Activity in Psoriatic Arthritis
The objective of the study is to investigate pain mechanisms, comorbidity status, biomarkers, patient reported outcome measures, ultrasonographic (US) inflammatory activity and association between these features in patients with…
- Conditions
- Psoriatic Arthritis, Psoriasis, Healthy Controls
- Trial name
- PIPA (NCT02572700)
- Testing
- Clinical examination, blood sampling, ultrasonic assessment, and questionnaires
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Frederiksberg University Hospital
Cognitive Impairment, Dementia
Determinants of Cognitive Impairment Among Geriatrics
This study aims to explore the determinants of cognitive impairment among Indonesian geriatrics in an Old Age Home.
- Conditions
- Cognitive Impairment, Dementia, Hearing Impairment, Vision Impairment and Blindness
- Trial name
- NCT03669536
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Gout Attack
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Evaluation of RPH-104 Administered at Different Doses to Patients With Acute Gout Attack
The primary goal of the study was to evaluate the parameters of efficacy, pharmacokinetics, pharmacodynamics, safety and tolerability of a single dose of RPH-104 in adult patients with acute gout attack.
- Trial name
- NCT04067492
- Testing
- RPH - 104, Voltaren®
- Where
- 11 sites in Russia
- Volunteers
- 47 people
- Sponsor
- R-Pharm
Mitochondrial Encephalomyopathies, Hereditary Spastic Paraplegia
Natural History Study of Patients with HPDL Mutations
This study uses medical records that allow retrospective data extraction of clinical manifestation to assess the natural history of HPDL mutations
- Conditions
- Mitochondrial Encephalomyopathies, Hereditary Spastic Paraplegia, Spastic Paraplegia, White Matter Disease
- Trial name
- NCT05848271
- Testing
- Patient Registry, Dry blood spots sampling
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Frozen Shoulder, Shoulder Capsulitis
The Effects of Two Different Treatment Protocols on Shoulder Function, Quality of Life, and Ultrasound Parameters in Patients With Frozen Shoulder
The goal of this interventional study is to compare the outcomes of two different injection aprroaches in patients with frozen shoulder.
- Conditions
- Frozen Shoulder, Shoulder Capsulitis, Shoulder Pain
- Trial name
- NCT05956171
- Testing
- Intra-articular corticosteroid injection, Ultrasound Guided Hydrodilatation with corticosteroid injection
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Myopathy
Maintenance of Muscle Mass in Older People: the Negative Impact of Statin Therapy
A major contributor to frailty and immobility in the elderly is the age related loss of muscle mass (sarcopenia). Cardiovascular disease (CVD) is the leading cause of mortality in the elderly, with high blood cholesterol and…
- Trial name
- NCT01047163
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Fibromyalgia Syndrome
Assessing Efficacy and Safety of Lacosamide Compared to Placebo in Reducing Signs and Symptoms of Fibromyalgia Syndrome.
This trial investigated the efficacy and safety of 400mg/day of lacosamide as compared to placebo in reducing the signs and symptoms of fibromyalgia syndrome.
- Trial name
- NCT00401830
- Testing
- Lacosamide
- Where
- 25 sites in United States
- Volunteers
- 159 people
- Sponsor
- UCB Pharma
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