Clinical trials: Musculoskeletal System
Axial Spondyloarthritis (axSPA)
Effects of Yoga Therapy in Rehabilitation Compared to Physiotherapy in Moderate Axial Spondyloarthritis (axSPA)
A few studies have evaluated the effectiveness of yoga therapy in patients with axial spondyloarthritis (axSPA). On the other hand, studies conducted in other chronic rheumatisms such as low back pain, rheumatoid arthritis or…
- Trial name
- YOKISPA (NCT06083090)
- Testing
- Yogatherapy, Physiotherapy
- Where
- 5 sites in France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoarthritis
A Prospective Randomized Trial Comparing Standard Ligament Reconstruction Tendon Interposition (LRTI) VS Ligament Reconstruction Tendon Interposition (LRTI) With an Interference Screw for Thumb Carpometacarpal Arthritis - Pilot Study
A Prospective Randomized Trial Comparing Standard Ligament Reconstruction Tendon Interposition (LRTI) VS Ligament Reconstruction Tendon Interposition (LRTI) with an interference screw for thumb carpometacarpal arthritis
- Trial name
- NCT02352610
- Testing
- LRTI, Biotenodesis Screw
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Andrew Trenholm
Contractures Resulting From Burn Scar Tissue
Joint Range of Motion in Burn Scars
The purpose of this study is to determine the relationship between cutaneous functional unit(CFU)recruitment throughout the available active range of motion of a prescribed joint in normal subjects and patients with burn scars.
- Trial name
- NCT01034813
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- United States Army Institute of Surgical Research
Idiopathic Short Stature
Growth Response in Short Children Suffering From a Disease With Growth Retardation and Treated With Somatropin
Growth hormone therapy will improve the height of short statured children with pathological conditions that lead to growth retardation.
- Trial name
- ISS (NCT00488124)
- Testing
- somatropin (Genotropin® treatment)
- Where
- 13 sites in Germany
- Volunteers
- 120 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
End Stage Liver Disease
Evaluation of Frailty and Functional Capacity in End-Stage Liver Disease
Development of fibrosis plays a main role in the pathophysiology of liver diseases. The rate of progression in fibrogenesis varies according to the type of underlying liver disease and varies with the environment and host-related…
- Trial name
- NCT04220723
- Testing
- Frailty Assessment, Functional Capacity Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Rheumatoid Arthritis, Rheumatic Diseases
Prediction of Methotrexate Response - A Pilot Study
The objective of this study is to identify genetic predictors of individual methotrexate (MTX) response in patients with rheumatic diseases by determining genetic and metabolomic factors related to nutrient metabolism and drug…
- Trial name
- MRS (NCT01726959)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Wake Forest University Health Sciences
Dialysis; Complications
Effect of Modifying Magnesium Concentration in Citrate-enriched Dialysate on Serum Magnesium Levels
Individuals with ESKD and treated with hemodialysis have a high mortality risk. Associative studies suggest a relationship between serum magnesium concentration and mortality risk.
- Trial name
- OMAGOD-1 (NCT07565779)
- Testing
- A - Dialysate magnesium 0.75, B - Dialysate magnesium 1.00 mmol/L
- Where
- 4 sites in Belgium
- Volunteers
- 54 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stroke; Sequelae
Postural Decoding for Post-Stroke Shoulder Pain: A RCT.
Brief Summary Purpose of the Study: This clinical trial aims to determine whether Postural Decryption Technique can effectively treat hemiplegic shoulder pain (HSP) in patients recovering from stroke.
- Trial name
- NCT06763796
- Testing
- Postural Decryption Technique, Traditional Chinese Medicine (TCM) Massage Therapy
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Shenzhen Baoan District Fuyong People's Hospital
Osteoarthritis of Knee
Clinical Efficacy and Safety of NEOIAL HC for Intra-articular Use in the Treatment of Severe Knee Osteoarthritis
Osteoarthritis (OA) is one of the most frequent causes of pain and disability in adults. According to the Osteoarthritis Research Society International (OARSI), at least 40% of people over the age of 65 suffer from symptomatic…
- Trial name
- NCT05936762
- Testing
- Neoial HC
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nextrasearch S.r.l.s.
Rheumatoid Arthritis
An Analysis of Peripheral Blood T Cell Subsets on Rheumatoid Arthritis
To study the effects of T cell in peripheral blood of patients with RA undergoing selective B cell depletion have not been studied.
- Trial name
- NCT00555542
- Testing
- rituximab
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Chinese University of Hong Kong
Rheumatoid Arthritis
Pictorial Representation of Illness and Self Measure
PRISM (Pictorial Representation of Illness and Self Measure) has been developed since the mid-1990s; the task was first developed as a simple measure of how a person was coping with his or her experience of illness.
- Trial name
- PRISM (NCT01707186)
- Where
- United Kingdom
- Volunteers
- 220 people
- Sponsor
- University of Oxford
Lateral Epicondylitis, (Tennis Elbow)
Dexamethasone Iontophoretic Patch for the Treatment of Pain Associated With Lateral Epicondylitis
The objective of this study is to determine the safety and efficacy of a dexamethasone iontophoretic transdermal patch for the treatment of pain associated with lateral epicondylitis (tennis elbow).
- Trial name
- NCT00794976
- Testing
- Dexamethasone Iontophoretic Patch (low dose), Dexamethasone Iontophoretic Patch (high dose), Dexamethasone Passive Patch
- Where
- 10 sites in United States
- Volunteers
- 216 people
- Sponsor
- Travanti Pharma Inc.
Lateral Epicondylitis, Tennis Elbow
Injection Therapy in Patients With Lateral Epicondylitis
Lateral epicondylitis is a painful enthesopathy of the common extensor tendon at the lateral part of the elbow, with a prevalence of 1-3 % in the general population.
- Trial name
- NCT04395417
- Testing
- Hyaluronic Acid, Prolotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Hacettepe University
Stroke, Osteoporosis
Osteoporosis After Stroke
The aim of this study was to investigate the clinical features affecting bone mineral density in plegic and non-plegic extremities in hemiplegic patients with stroke in the subacute and chronic phases.
- Trial name
- NCT07059468
- Testing
- Bone mineral density/ Bone mineral density (BMD) will be measured on the lumbar spine (L1-L4) and femoral neck by dual X-ray absorptiometry (DXA)
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Hallux Rigidus
Motion Analysis in Patients With Hallux Rigidus
The aim was to investigate with a multi-segmental foot model the kinetic and kinematic in patients with a hallux rigidus, before and after different type of surgery.
- Trial name
- NCT01804491
- Testing
- Motion Analysis
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Fibromyalgia Syndrome, Fibromyalgia Impact Questionnaire
Effects of Conscious Connected Breathing Exercises on Fibromyalgia
Our aim in this study is to investigate the effects of conscious connected breathing exercises on sexual function, sleep, and mood in fibromyalgia patients.
- Conditions
- Fibromyalgia Syndrome, Fibromyalgia Impact Questionnaire, Breathing Pattern Disorder, Female Sexual Dysfunction (FSD)
- Trial name
- NCT07030374
- Testing
- conscious connected breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Adana City Training and Research Hospital
Patellofemoral Pain Syndrome
Proprioceptive Training vs. Hip Abductor With External Rotator Strengthening in Patients With Patellofemoral Pain
Patellofemoral pain syndrome (PFPS) is a common musculoskeletal disorder characterized by an insidious onset of pain in the knee's anterior /retro-patellar / peripatellar region.
- Trial name
- NCT05698797
- Testing
- Hip strengthening exercises, Proprioceptive training, Conventional physical therapy
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- King Saud University
Ankylosing Spondylitis
Efficacy and Safety of Loxoprofen Hydrogel Patch in Patients With Ankylosing Spondylitis
To assess the efficacy and safety of loxoprofen sodium hydrogel patch (LX-P) versus loxoprofen sodium tablet (LX-T) in patients with active ankylosing spondylitis(AS).
- Trial name
- NCT03800797
- Testing
- Loxoprofen sodium hydrogel patch, Loxoprofen sodium tablet
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Sun Yat-sen University
Musculoskeletal Abnormality, Pediatric
Reliability and Acceptability of Real-time Virtual Video Pediatric Gait, Arms, Legs and Spine (V-pGALS)
The use of telemedicine in musculoskeletal assessment has been historically low. The current COVID 19 global pandemic has forced a paradigm shift with many centers rapidly adopting virtual visits to conduct care resulting in…
- Trial name
- NCT04668820
- Testing
- video Pediatric Gait, Arms, Legs and Spine (V-pGALS)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Marmara University
Osteosarcoma, Sarcoma
A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Advanced Bone and Soft Tissue Tumors
9 participants are expected to be enrolled for this open，Single-armed clinical trial to evaluate the safety and efficacy of the recombinant herpes simplex virus Ⅰ, R130 in patients with advanced bone and soft tissue tumors.
- Conditions
- Osteosarcoma, Sarcoma, Soft Tissue Sarcoma, Bone Tumor
- Trial name
- NCT06171282
- Testing
- Recombinant oncolytic herpes simplex virus type Ⅰ (R130)
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Shanghai Yunying Medical Technology