Clinical trials: Myalgic Encephalomyelitis Chronic Fatigue Syndrome
Fatigue, Cancer
Patient-Centered Assessment of Symptoms and Outcomes
Background: The cause of fatigue is not well understood. It can be felt differently by different people. Some people think there are different types of fatigue, with different causes.
- Conditions
- Fatigue, Cancer, CFS, ME/CFS
- Trial name
- NCT03952624
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Post-Viral Fatigue Syndrome
Rehabilitation Robot in Patients With Post-Coronavirus Disease (COVID-19) Fatigue Syndrome
The aim of the study is to compare the effectiveness of two models of rehabilitation: traditional neurological rehabilitation, and neurological rehabilitation combined with a rehabilitation robot (Luna by EGZOTech).
- Trial name
- NCT05130736
- Testing
- Robot rehabilitation
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Poznan University of Medical Sciences
Chronic Fatigue Syndrome
Myalgic Encephalomyelitis Chronic Fatigue at the National Institutes of Health
Background: Post-Infectious Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (PI-ME/CFS) refers to long-lasting and disabling fatigue or malaise, inability to recover after exercise, and physical and emotional discomfort that…
- Trial name
- NCT02669212
- Testing
- Cardiopulmonary Exercise Test (CPET)
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Chronic Fatigue Syndrome
Patient-Partner Stress Management Effects on Chronic Fatigue Syndrome Symptoms and Neuroimmune Process
The purpose of this study is to test the effects of a videotelephone-delivered patient-partner dual-focused cognitive behavioral stress management intervention on chronic fatigue syndrome (CFS) symptoms and related psychosocial…
- Trial name
- NCT01650636
- Testing
- Patient-Partner Videotelephone-delivered Health Information (PP-T-HI), Patient-Partner Videotelephone-delivered Cognitive Behavioral Stress Management intervention (PP-T-CBSM)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Miami
Chronic Fatigue Syndrome, Idiopathic Chronic Fatigue
Investigator Initiated Clinical Study to Explore the Efficacy and Safety of Human Placenta Hydrolysate in the Chronic Fatigue Patients
GCJBP Laennec Injection contains a variety of cytokines derived from human placenta, amino acids, peptides, nucleobases, and carbohydrates. This product is approved for improving liver function.
- Trial name
- NCT01742013
- Testing
- GCJBP Laennec Inj.
- Where
- 2 sites in South Korea
- Volunteers
- 78 people
- Sponsor
- Ho Cheol Shin, M.D., Ph.D.
Post-COVID ME/CFS
Hyperbaric High Pressure Oxygen Therapy in Post-COVID Syndrome and ME/CFS
The objective of this observational study is to document symptom progression in 60 patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) who undergo Hyperbaric Oxygen Therapy (HBOT) following COVID or other…
- Trial name
- NCT06118138
- Testing
- Hyperbaric oxygen therapy (HBOT)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Chronic Fatigue Syndrome
Efficacy of Web-based Cognitive Behavioural Treatment for Adolescents With Chronic Fatigue Syndrome
The aim of this study is to determine the efficacy of FITNET (web-based cognitive behavioural treatment) for adolescents with Chronic Fatigue Syndrome (CFS) in The Netherlands.
- Trial name
- FitNet (NCT00893438)
- Testing
- FitNet treatment, Usual care
- Where
- 2 sites in Netherlands
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis
We are studying the effect of a mind-body treatment for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with or without Long COVID (LC).
- Trial name
- MILES (NCT06933173)
- Testing
- Dynamic neural retraining system
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University of Alberta
Myalgic Encephalomyelitis, Post-acute COVID-19 Syndrome
Inspiratory Muscle Training in ME/CFS and COVID-19 Survivors
Coronavirus-2019 (COVID-19) is a viral disease leading to respiratory dysfunction, but it may also affect the brain and result in the development of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
- Trial name
- Inspire ME (NCT05196529)
- Testing
- Inspiratory muscle training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- York University
Post-COVID-19 Syndrome, Post-COVID Syndrome
Post-COVID-19 Chronic Fatigue Syndrome
Fatigue is recognized as one of the most commonly presented long-term complaints in individuals previously infected with SARS-CoV-2.
- Trial name
- NCT05642923
- Testing
- Synthetic Vitamin B1
- Where
- Egypt
- Volunteers
- 528 people
- Sponsor
- ClinAmygate
Multicausal Fatigue, Fatigue
Micro-choice-based Intervention for Multicausal Fatigue
This proof-of-concept study aims to evaluate the feasibility, acceptability, and potential benefits of a novel multimodal approach: the micro-choice-based intervention.
- Conditions
- Multicausal Fatigue, Fatigue, Post COVID Condition, Long COVID Syndrome
- Trial name
- CHOOSE-POC (NCT07726082)
- Testing
- Micro-choice-based intervention
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University Hospital, Basel, Switzerland
Chronic Fatigue Syndrome
Drug Intervention in Chronic Fatigue Syndrome
Based on pilot patient observations,the investigators anticipate that chronic fatigue syndrome (CFS) patients may benefit from B-cell depletion therapy.
- Trial name
- KTS-1-2008 (NCT00848692)
- Testing
- Rituximab
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Haukeland University Hospital
Long COVID, Chronic Fatigue Syndrome
Telerehabilitation for Post COVID-19 Condition
Telerehabilitation is a great alternative to offering care during a global pandemic. 85% of patients with COVID-19 report persistent symptoms up to 8 months after the infection.
- Trial name
- Telecovie (NCT05973136)
- Testing
- Telerehabilitation program based on cardiorespiratory principles
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- Université de Sherbrooke
Chronic Fatigue Syndrome, Intensive Care Unit
Chronic Fatigue Etiology and Recovery in Covid-19 Patients: the Role of Fatigability
Chronic fatigue is the most common and debilitating symptom in intensive care unit (ICU) survivors. Indeed, it has been widely reported that patients who stayed in ICU for prolonged periods report a feeling of tiredness for…
- Conditions
- Chronic Fatigue Syndrome, Intensive Care Unit, Muscle
- Trial name
- FatCovid-19 (NCT04363606)
- Testing
- Questionnaires, blood test, Maximal effort test
- Where
- 8 sites in France
- Volunteers
- 69 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Chronic Fatigue Syndrome, Behavioral Therapy Targeted to Sleep Problems
Behavioral Insomnia Therapy With Chronic Fatigue Syndrome
The purpose of this study is to determine how best to manage the sleep problems of people with Chronic Fatigue Syndrome. This study is being conducted to determine how improvements in sleep affect other Chronic Fatigue symptoms…
- Trial name
- NCT00540254
- Testing
- Cognitive Behavioral Therapy, Usual Care for Chronic Fatigue Syndrome (Active Control Group)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (ICD-10 G93.3)
Investigating the Effects of Intermittent Hypoxia-Hyperoxia Treatment (IHHT) in People With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) to Improve Fatigue, Pain, and Quality of Life by Targeting Mitochondrial Dysfunction and Autonomic Nervous System Impairment
This study is testing a new treatment for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and long-term symptoms after COVID-19.
- Trial name
- REenergizeME (NCT07317401)
- Testing
- Intermittent hypoxia-hyperoxia treatment (IHHT)
- Where
- Denmark
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Melatonin and Zinc Administration on Cardinal Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
The aim of the study is to investigate the effects of oral melatonin and zinc supplementation on core features in individuals with ME/CFS
- Trial name
- MelatoZincME (NCT05454683)
- Testing
- melatonin plus zinc, isomaltose and magnesium stearate
- Where
- Spain
- Volunteers
- 106 people
- Sponsor
- Laboratorios Viñas, S.A.
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Chronic Infections and Inflammation in ME/CFS: An Observational Study
CHIIME is a study of people who have myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). People who do not have this condition will also be enrolled.
- Trial name
- CHIIME (NCT07227441)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Fibromyalgia, Chronic Fatigue Syndrome
Tracking Peripheral Immune Cell Infiltration of the Brain in Central Inflammatory Disorders Using [Zr-89]Oxinate-4-labeled Leukocytes.
This study will use brain Positron Emission Tomography/ Magnetic Resonance Imaging (PET/MRI) and an investigational radioactive drug called [Zr-89]oxine to track the location of white blood cells (also called leukocytes) in the…
- Conditions
- Fibromyalgia, Chronic Fatigue Syndrome, Multiple Sclerosis, Healthy
- Trial name
- NCT03807973
- Testing
- [Zr-89]Oxine-labeled leukocytes PET/MRI
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham