Clinical trials: Myelopathy, Compressive
Spinal Cord Neoplasms, Spinal Neoplasms
Intradurale Spinal Tumors: Management and Treatment
Intradurale spinal tumors are rare neoplastic lesions that involve the spinal cord and surrounding structures and may cause neurological symptoms such as pain, motor deficits, sensory disturbances, and sphincter dysfunction.
- Trial name
- GTTIR (NCT07488702)
- Testing
- Surgical Resection of Intradural Spinal Tumors
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Cancer, Hematologic Malignancies
Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma
The purpose of this study is to determine if denosumab is non-inferior to zoledronic acid in the treatment of bone disease from multiple myeloma.
- Conditions
- Cancer, Hematologic Malignancies, Multiple Myeloma, Oncology
- Trial name
- NCT01345019
- Testing
- Denosumab, Zoledronic acid, Denosumab (for the open-label treatment phase)
- Where
- 309 sites in United States, Australia and 27 more
- Volunteers
- 1,718 people
- Sponsor
- Amgen
Pain, Radiation Toxicity
Spinal Cord Compression Re-Treat Study
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Radiation therapy may be effective in treating malignant spinal cord compression in patients who have received previous radiation therapy to the spine.
- Conditions
- Pain, Radiation Toxicity, Spinal Cord Compression, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00974168
- Testing
- Cumulative BED ≤ 100, Cumulative BED ≤ 130 Gy2
- Where
- 2 sites in Ireland
- Volunteers
- 22 people
- Sponsor
- Cancer Trials Ireland
Cervical Spinal Cord Injury, Spinal Cord Injuries
Restoring Hand Function Utilizing Nerve Transfers in Persons With Cervical Spinal Cord Injuries
The primary objective of this study is to evaluate the safety and efficacy of nerve transfer surgery for restoring hand function as a therapy for patients with cervical spinal cord injury.
- Conditions
- Cervical Spinal Cord Injury, Spinal Cord Injuries, Traumatic Spinal Cord Compression
- Trial name
- NCT03451474
- Testing
- Upper extremity nerve transfer surgery
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Compression Due to Metastasis to Spine
RAdiotherapy for Metastatic Spinal Cord Compression with Increased Radiation DosES
This clinical study aims to investigate whether high-precision radiotherapy, as supposed, leads to a better control of the irradiated spinal cord metastases when compared to conventional radiotherapy.
- Trial name
- RAMSES-01 (NCT04043156)
- Testing
- High-precision RT
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- University Hospital Schleswig-Holstein