Clinical trials: Myocardial Deformation, open to volunteers
Heart Disease
Assessment of Cardiac Function and Anesthesia Depth in Patients Undergoing Cardiac Surgery
The SHAPE study is a prospective, randomized study evaluating changes in cardiac function in adult patients undergoing cardiac surgery with cardiopulmonary bypass.
- Trial name
- SHAPE (NCT07770269)
- Testing
- BIS-guided anesthesia: BIS 45-55, BIS-guided anesthesia: BIS 30-35
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- AHEPA University Hospital
Healthy Participants, Reference Values
Cardiac Normal Values Assessed by Magnetic Resonance Imaging
This study carried out a study enrolled healthy volunteers to comprehensively provide age and sex specific reference values of the normal cardiac structure and function of Chinese adults, using the steady-state free precession…
- Trial name
- NCT05346094
- Testing
- No intervention
- Where
- China
- Volunteers
- 938 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Smoking Cessation, Arterial Stiffness
The Effect of Cytisine Treatment for Smoking Cessation on Cardiovascular Function in Adult Smokers
Introduction: Pharmacological interventions can enhance smoking cessation success and long-term abstinence. Cytisine, a plant derived alkaloid, is a selective partial agonist at alpha-4 beta-2 nicotinic acetylcholine receptors…
- Conditions
- Smoking Cessation, Arterial Stiffness, Endothelial Dysfunction
- Trial name
- Cytisin-angio (NCT06885970)
- Testing
- Cytisinicline administration
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- University of Athens
Myocardial Infarction (MI), Diabete Type 2
The Effect of Sodium Glucose Co-trnasportert Type 2 Inhibitors on Arterial Stiffness, Endothelial Glycocalyx Thickness and Cardiac Deformation After Acute Myocardial Infarction
Acute myocardial infarction (MI) remains one of the leading causes of cardiovascular morbidity and mortality worldwide. It most commonly occurs due to acute coronary artery occlusion following rupture or erosion of an…
- Trial name
- SGLT2i-MI-glyc (NCT07469943)
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- University of Athens
Peripheral Artery Disease, Heart Failure
Myocardial Dysfunction Evaluation in Lower Extremity Arterial Disease Patients With Deformation Analysis
Single centre observational study to assess lower extremity arterial disease (LEAD) patients' cardiac dysfunction with strain analyses and to assess connections between cardiac dysfunction, metabolomic changes and target organ…
- Trial name
- MEDAL (NCT06215248)
- Where
- Estonia
- Volunteers
- 162 people
- Sponsor
- Tartu University Hospital
Lipoprotein Disorder, Arterial Stiffness
The Effect of Lipoprotein (a) on Arterial Stiffness, Endothelial Function and Myocardial Deformation
1. Introduction Lipoprotein(a), or Lp(a), is a type of lipoprotein that is structurally similar to LDL (low-density lipoprotein) but carries an additional protein called apolipoprotein (a). 2.
- Conditions
- Lipoprotein Disorder, Arterial Stiffness, Endothelial Dysfunction
- Trial name
- Lpa_endo (NCT07324902)
- Where
- 2 sites in Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Athens
Myocardial Infarction, Acute, Myocardial Strain
Assessment of the Effects of Long-term Lipid-lowering Therapy in Patients With Primary STEMI or NSTEMI
In a single-center, open-label, prospective, controlled, clinical study, it is planned to include 300 patients hospitalized in the cardiology department of SBHI Penza regional clinical hospital n.a. N.N. Burdenko.
- Conditions
- Myocardial Infarction, Acute, Myocardial Strain, Arterial Stiffness, Quality of Life
- Trial name
- CONTRAST-2 (NCT04347434)
- Testing
- Atorvastatin 80mg
- Where
- Russia
- Volunteers
- 300 people
- Sponsor
- Penza State University
Cardiovascular Diseases, Ischaemic Heart Disease
Machine Learning in Quantitative Stress Echocardiography
Greater diagnostic accuracy is required to find out who is at risk of a heart attack as this can reduce the requirement of more invasive downstream tests and thereby improve the patient experience and also reduce their exposure…
- Trial name
- MLQSE (NCT04193475)
- Testing
- Analysis
- Where
- United Kingdom
- Volunteers
- 1,250 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust