Clinical trials: Myocardial Infarct
Unstable Angina
Ischemia Driven Enoxaparin Therapy in ACS Presenting as Low Risk (IDEAL)
The purpose of this study is to determine whether enoxaparin (an anticoagulant) is effective in the treatment of patients presenting to the emergency room with chest pain and no electrocardiogram or bloodwork evidence of a heart…
- Trial name
- IDEAL (NCT00518245)
- Testing
- enoxaparin
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- Canadian Heart Research Centre
Acute Coronary Syndrome, Acute Myocardial Infarction
Sicilian Administrative Data Base Study in Acute Coronary Syndrome Patients
Thi is an observational, non interventional, cohort analysis by using administrative databases (drugs treatment, laboratory and diagnostic tests, specialist visits and hospitalizations) of Sicilia region to evaluate treatment…
- Trial name
- HEALTH-DB ACS (NCT01678339)
- Where
- Italy
- Sponsor
- AstraZeneca
Chest Pain, Acute Coronary Syndrome, Myocardial Infarction
Magnetocardiography in the Accurate Identification of Severe Coronary Lesions and Myocardial Necrosis
Magnetocardiography (MCG) is a promising noninvasive and accurate method for detecting myocardial ischemia. Although progress has been made in this area, there is a lack of studies using up-to-date examination instruments for the…
- Trial name
- NCT05392712
- Testing
- Magnetometer
- Where
- China
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Acute Myocardial Infarction
Phase II Clinical Trial to Evaluate the Benefits of Postconditioning in ST-Elevation Myocardial Infarction (STEMI)
This study will evaluate change in heart muscle function from baseline to three months and twelve months in participants who present with a heart attack and a completely occluded coronary artery.
- Trial name
- NCT01324453
- Testing
- Post Conditioning + Primary PCI, Standard Primary PCI
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Minneapolis Heart Institute Foundation
Acute Coronary Syndrome
Clinical Governance of Patients With Acute Coronary Syndrome in Italy
This is a prospective, observational, multicenter study that enroll consecutive and all-comers patients hospitalized with a diagnosis of Acute Coronary Syndrome (ACS) at admission.
- Trial name
- NCT04255537
- Where
- 9 sites in Italy
- Volunteers
- 3,000 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Heart Injuries
Subclinical Hypothyroidism and Acute Anterior Myocardial Infarction: Is it Cardio-protective or Not?
The study plans to investigate whether recovery of the heart function after acute anterior myocardial infarction is dependent upon improvement in thyroid gland functioning.
- Trial name
- NCT03017157
- Testing
- Echo-cardiogram, Blood test
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hillel Yaffe Medical Center
Myocardial Infarction
Effects of Recombinant Human Erythropoietin on Platelet Function in Patients With Acute Myocardial Infarction
The purpose of this study is to see if a naturally-occurring hormone called erythropoietin changes the action of platelets in the blood.
- Trial name
- NCT00367991
- Testing
- Recombinant human erythropoietin alfa (drug)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Yale University
Acute Myocardial Infarction, Acute Myocardial Ischemia
Study of Dutogliptin in Combination With Filgrastim in Post-Myocardial Infarction
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Safety and Efficacy Study of Dutogliptin in Combination with Filgrastim in Early Recovery Post-Myocardial Infarction
- Conditions
- Acute Myocardial Infarction, Acute Myocardial Ischemia, STEMI - ST Elevation Myocardial Infarction
- Trial name
- NCT03486080
- Testing
- Dutogliptin Tartrate, Filgrastim Injectable Product
- Where
- 12 sites in Austria, Belgium and 3 more
- Volunteers
- 49 people
- Sponsor
- Recardio, Inc.
Cardiogenic Shock
Study Comparing the Efficacy and Tolerability of Epinephrine and Norepinephrine in Cardiogenic Shock
The efficacy and tolerability of norepinephrine and epinephrine in cardiogenic shock after reperfused myocardial infarction will be compared, by following cardiac index evolution as main criteria.
- Trial name
- OptimaCC (NCT01367743)
- Testing
- epinephrine perfusion, norepinephrine perfusion
- Where
- 11 sites in France
- Volunteers
- 58 people
- Sponsor
- Central Hospital, Nancy, France
Coronary Angiography, Dipeptidyl Peptidase 4
Prognostic Value of Plasma DPP4 Activity in ST-elevation Myocardial Infarction Patients
Increased plasma DPP4 activity (DPP4a) could predict both subclinical and new-onset atherosclerosis, and our previous study has found that the DPP4a was significantly lower in MI patients compared with patients having chest pain…
- Trial name
- NCT03046576
- Testing
- plasma DPP4 activity
- Volunteers
- 625 people
- Sponsor
- Chinese PLA General Hospital
Myocardial Infarction (MI), Hypertrophic Cardiomyopathy (HCM)
The Application of T1 Mapping in Real-World
The goal of this observational study is to create a comprehensive real-world spectrum of T1 mapping measurements across different heart conditions.
- Conditions
- Myocardial Infarction (MI), Hypertrophic Cardiomyopathy (HCM), Dilated Cardiomyopathy (DCM), Arrhythmogenic Cardiomyopathy
- Trial name
- NCT07354646
- Testing
- Magnetic Resonance Imaging with Contrast
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Platelet Aggregation, Acute Myocardial Infarction
Effect of Exercise on Platelet Reactivity After Myocardial Infarction
This project aims to evaluate, in recent post-acute myocardial infarction (AMI) patients on dual antiplatelet therapy, the impact of regular exercise training on platelet aggregability and the correlation between the level of…
- Conditions
- Platelet Aggregation, Acute Myocardial Infarction, Exercise Training
- Trial name
- NCT02958657
- Testing
- Exercise Training
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
Heart Failure With Reduced Ejection Fraction, Cardiogenic Shock
Pulmonary Artery Catheterization and Carvedilol Early Initiation in Cardiogenic SHOCK Due to HFrEF
This study aims to compare the impact of hemodynamic monitoring using pulmonary artery catheter (PAC) on survival and inotropic agent reduction in patients with cardiogenic shock caused by heart failure with reduced ejection…
- Trial name
- PACE-SHOCK (NCT06078436)
- Testing
- Pulmonary artery catheter
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Min-Seok Kim
Cardiogenic Shock
Randomized Evaluation of Istaroxime for Stabilization in Acute Heart Failure-Cardiogenic Shock
The goal of this clinical trial is to learn if the drug istaroxime works to treat cardiogenic shock due to acute heart failure in adults. It will also learn about the safety of istaroxime.
- Trial name
- RESCUE HF-CS (NCT07583446)
- Testing
- istaroxime
- Where
- Armenia
- Volunteers
- 600 people
- Sponsor
- Seismic Pharmaceuticals Operations LLC
Infarction, Myocardial
Autonomic Regulation Trial (ART)
The purpose of this study was to develope and evaluate a new method for risk stratification which predicts high mortality risk in patients with cardiac disease based on simultateous examination of high resolution ECG, continuous…
- Trial name
- NCT00196274
- Where
- 2 sites in Germany
- Volunteers
- 1,000 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Myocardial Injury, Myocardial Infarction
Prevention of Myocardial Injury in Non-cardiac Surgery
Worldwide, more than 200 million patients have major non-cardiac surgery annually and a significant proportion of these patients suffer major cardiovascular complications (e.g.
- Trial name
- PIXIE (NCT02344797)
- Testing
- Remote ischemic preconditioning
- Where
- 3 sites in Denmark
- Volunteers
- 573 people
- Sponsor
- Zealand University Hospital
Myocardial Infarction
Evaluation of the Predictive Effect of Inflammatory Markers in MI Patients
Acute myocardial infarction (AMI), triggered by myocardial ischemia and reperfusion injury, is a disease with high morbidity and mortality, and there is a tendency for its incidence to increase at younger ages.
- Trial name
- NCT05479838
- Testing
- Percutaneous coronary intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Abant Izzet Baysal University
Chronic Ischemic Left Ventricular Dysfunction, Myocardial Infarction
The Transendocardial Autologous Cells (hMSC) or (hMSC) and (hCSC) in Ischemic Heart Failure Trial.
Before initiating the full randomized study, a Pilot Safety Phase will be performed. In this phase the composition of cells administered via the Biosense Webster MyoStar NOGA Injection Catheter System will be tested.
- Trial name
- TAC-HFT-II (NCT02503280)
- Testing
- Autologous hMSCs, Autologous Human C-Kit CSCs II, Biosense Webster MyoStar NOGA Injection Catheter System
- Where
- United States
- Sponsor
- Joshua M Hare
Perioperative Bleeding, Venous Thrombosis
PeriOperative ISchemic Evaluation-3 Trial
This study is a multicentre, international, randomized controlled trial of tranexamic acid (TXA) versus placebo and, using a partial factorial design, of a perioperative hypotension-avoidance versus hypertension-avoidance…
- Conditions
- Perioperative Bleeding, Venous Thrombosis, Arterial Thrombosis
- Trial name
- POISE-3 (NCT03505723)
- Testing
- Tranexamic Acid, Perioperative hypotension-avoidance strategy, Perioperative hypertension-avoidance strategy
- Where
- 114 sites in United States, Australia and 21 more
- Volunteers
- 9,535 people, healthy volunteers welcome
- Sponsor
- Population Health Research Institute
ST Elevation Myocardial Infarction
MGuard™ Prime Embolic Protection Stent in Patients With Acute ST Elevation Myocardial Infarction
Prospective, non-randomized, single arm, multicenter observational study. The objective is to evaluate the safety and efficacy of the MGuard™ Prime stent in the treatment of de novo stenotic lesions in coronary arteries in…
- Trial name
- e-MASTER (NCT02292823)
- Testing
- MGuard™ Prime Embolic Protection Stent System
- Where
- Netherlands
- Volunteers
- 63 people
- Sponsor
- InspireMD