Clinical trials: Myocardial Ischemia
Acute Coronary Syndrome (ACS), Reactive Hyperemia
Effect of Olive Leaf Extracts on Endothelial Dysfunction in Patients With Acute Coronary Syndrome
the study aims to examine the short-term (30 days) effects of olive leaf extract on endothelial function in patients with acute coronary syndrome (ACS).
- Conditions
- Acute Coronary Syndrome (ACS), Reactive Hyperemia, Endothelial Dysfunction
- Trial name
- ACS_ATHEROLIV (NCT06723002)
- Testing
- Atherolive 500mg/day, Atherolive 1000/day, Placbo_Atherolive
- Volunteers
- 300 people
- Sponsor
- University of Monastir
Stent Thrombosis, Acute Coronary Syndrome
Stent Thrombosis In Acute Coronary Syndromes
The purpose of this study is to better understand what treatment methods result in the best outcomes for patients who have heart attacks due to blood clots forming within stents.
- Trial name
- NCT00931502
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of California, Davis
Acute Coronary Syndrome
Effect of CER-001 on Atherosclerosis in Acute Coronary Syndrome (ACS) Patients - Efficacy and Safety: The CHI SQUARE Trial
Cardiovascular disease remains the most pressing healthcare issue for developed countries and is becoming so for developing countries. There are a number of chronic therapies available for long-term management of risk.
- Trial name
- CHI SQUARE (NCT01201837)
- Testing
- CER-001
- Where
- 47 sites in United States, Canada and 2 more
- Volunteers
- 507 people
- Sponsor
- Cerenis Therapeutics, SA
Coronary Heart Disease and Stroke
A Comparison of the Estimates of Fuwai and Reynolds Risk Model
There are many risk prediction models. And their estimates are different. This study aimed to investigate the differences between the estimates of Fuwai and Reynolds risk model in Chinese, and investigate the reason for the…
- Trial name
- NCT02241239
- Where
- 2 sites in China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Wuhan Asia Heart Hospital
Coronary Microvascular Dysfunction, Myocardial Ischemia
Diagnostic and Prognostic Value of Angiography-derived IMR
The importance of the microvasculature in determining clinical outcomes has been highlighted in patients with coronary artery disease (CAD).
- Trial name
- CHART-MiCro (NCT04825028)
- Testing
- Angiography-drived Index of Microcirculatory Resistance
- Where
- China
- Volunteers
- 271 people
- Sponsor
- Shanghai Zhongshan Hospital
Coronary Artery Disease, Diabetes Mellitus Type 2
Effects of Hyperglycemia on Myocardial Perfusion in Humans With and Without Type 2 Diabetes
The overall goal of this proposal is to determine the effects of acute hyperglycemia and its modulation by Glucagon-like Peptide-1 (GLP-1) on myocardial perfusion in type 2 diabetes (DM).
- Trial name
- GLP-1 (NCT01021865)
- Testing
- Glucagon-Like-Peptide-1/Regadenoson/Perflutren Lipid Microsphere
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cardiovascular Diseases, Coronary Disease
Trends in Trans-Fatty Acid Intake Between 1980 and 1997
To examine trends in trans-fatty acid intake by using newly available nutrient data to recalculate 24 dietary recalls from the Minnesota Heart Survey.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases
- Trial name
- NCT00006500
- Sponsor
- University of Minnesota
Cardiovascular Diseases, Heart Diseases
Sex Steroid Hormones and Risk of CHD in Women
To investigate the relationship between endogenous estrogen and androgen levels and risk of coronary heart disease among postmenopausal women in the Women's Health Initiative-Observational Study (WHI-OS).
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Postmenopause
- Trial name
- NCT00006407
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Coronary Syndrome, Myocardial Infarction
Hepatocyte Growth Factor (HGF) Concentration in Myocardial Infarction
This is the continuation of previous study (registration number: NCT00844987) which revealed that hepatocyte growth factor (HGF) is a very early, good marker of myocardial injury and prognostic factor for post myocardial…
- Trial name
- NCT01233336
- Where
- Poland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Acute Coronary Syndrome
Increasing Exercise Adherence After Percutaneous Coronary Intervention With the Fitbit Charge HR Device
Design: Single center, prospective, randomized study that will compare activity levels in patients who complete cardiac rehabilitation after clinically indicated percutaneous coronary intervention with and without use of the…
- Trial name
- INCENTIVE (NCT02788929)
- Testing
- Fitbit Charge HR
- Volunteers
- 40 people
- Sponsor
- North Texas Veterans Healthcare System
Coronary Artery Disease
BIOFLOW-INDIA Safety and Clinical PerFormance of the Drug Eluting ORSIRO Stent in Single de Novo Coronary Artery Lesions
The objective of this clinical investigation is to assess the safety and clinical performance of the Orsiro Limus Eluting Stent System in Indian subjects with single de-novo coronary artery lesions.
- Trial name
- NCT01426139
- Testing
- Percutaneous Coronary Intervention Biotronik Orsiro DES
- Where
- 4 sites in India
- Volunteers
- 120 people
- Sponsor
- Biotronik AG
Hypertension, Renovascular, Renal Artery Stenosis
Cardiovascular, Renal and Metabolic Profile in Patients With Acute Myocardial Infarction (REN-ACS)
Aims assessment of renal artery stenosis incidence in consecutive AMI patients included in the Romanian National Programme of Primary Percutaneous Revascularisation; generating a cardio-renal-metabolic profile in patients with…
- Conditions
- Hypertension, Renovascular, Renal Artery Stenosis, Myocardial Infarction
- Trial name
- REN-ACS (NCT02388139)
- Testing
- renal artery angiography, coronarography, coronary angioplasty
- Where
- Romania
- Volunteers
- 200 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
STEMI - ST Elevation Myocardial Infarction
Bivalirudin in Late PCI for Oatients With STEMI
Bivalirudin is recomended by guidelines during primary PCI procedure for patients with STEMI. However, there is a large number of STEMI patients who missed the primary PCI.
- Trial name
- BETTER (NCT04185077)
- Testing
- Bivalirudin, Heparin
- Volunteers
- 1,200 people
- Sponsor
- Second Xiangya Hospital of Central South University
Shock, Cardiogenic
A Study of the Safety and Efficacy of Nitric Oxide Reduction in Patients With Cardiogenic Shock After a Heart Attack
Tilarginine Acetate Injection is a new type of drug that temporarily stops the body from making a bodily substance called nitric oxide. The body may produce excess nitric oxide following severe heart damage leading to shock.
- Trial name
- NCT00112281
- Testing
- Tilarginine Acetate Injection intravenous infusion
- Where
- 102 sites in United States, Canada
- Volunteers
- 658 people
- Sponsor
- Arginox Pharmaceuticals
Coronary Artery Stenosis
Coronary Non-slip Balloon Catheter in Patients With Coronary Artery Stenosis(CREST)
This is a prospective, multicenter, randomized controlled clinical investigation aiming to evaluate the safety and effectiveness of non-slip balloon catheter for the treatment of patients with coronary artery stenosis.
- Trial name
- NCT05606367
- Testing
- Non-slip Balloon Catheter of Shanghai MicroPort Rhythm, NSE Coronary Dilatation Catheter
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai MicroPort Rhythm MedTech Co., Ltd.
Carotid Artery Diseases, Coronary Artery Disease
Outcome of LA Versus GA for Staged CEA Prior To CABG
A retrospective analysis of all patients that underwent carotid endarterectomy (CEA) for stenotic disease - diagnosed at pre-operative investigation - prior to CABG as staged operation within 6- months.
- Conditions
- Carotid Artery Diseases, Coronary Artery Disease, Stroke
- Trial name
- NCT04901000
- Testing
- Carotid endarterectomy
- Volunteers
- 44 people
- Sponsor
- Thomas Aherne
Ischemic Heart Disease, Angina Pectoris
Absorb GT1 Japan PMS
The purpose of the Surveillance is to know the frequency and status of adverse device effects and adverse events in order to assure the safety of the new medical device, and to collect efficacy and safety information for…
- Conditions
- Ischemic Heart Disease, Angina Pectoris, Coronary Artery Disease, Coronary Artery Occlusion
- Trial name
- NCT03409731
- Testing
- ABSORB GT1 BVS
- Where
- 15 sites in Japan
- Volunteers
- 135 people
- Sponsor
- Abbott Medical Devices
Coronary Artery Disease, Atherosclerotic Cardiovascular Disease
AI-CCTA for Predicting Cardiovascular Events in CAD
This multicenter, retrospective registry study aims to evaluate the value of artificial intelligence (AI)-derived coronary CT angiography (CCTA) parameters in predicting long-term cardiovascular events in patients with coronary…
- Trial name
- MAPLE (NCT07832175)
- Testing
- No intervention
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Acute Coronary Syndrome, Left Ventricle Remodeling
Predictive Value of Risk Scores in Acute Coronary Syndrome
role of different risk scores in acute coronary syndrome to predict left ventricular remodeling
- Conditions
- Acute Coronary Syndrome, Left Ventricle Remodeling, Risk Scores
- Trial name
- NCT03549481
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- shaimaa Mostafa
Non-ischemic Cardiomyopathy, Dilated Cardiomyopathy (DCM)
Multimodal and Multidisciplinary Approach to Optimize Diagnostic, Prognostic, and Therapeutic Management of Patients with Non-ischemic Cardiomyopathies and Arrhythmogenic-inflammatory Phenotypes: a Multicenter, Observational, Retrospective and Prospective Registry Study.
Non-ischemic cardiomyopathies (NICM) represent a heterogeneous group of pathologies characterized by absence of obstructive disease of the epicardial coronary vessels and distinct structural and functional changes of the…
- Conditions
- Non-ischemic Cardiomyopathy, Dilated Cardiomyopathy (DCM), Hypertrophic Cardiomyopathy (HCM), Restrictive Cardiomyopathy
- Trial name
- AINICM (NCT06607471)
- Testing
- Support treatment, cardiac medical treatment, aetiology-specific treatment, device implant, arrhythmia ablation, Support treatment, cardiac medical treatment, aetiology-specific treatment
- Where
- Italy
- Volunteers
- 15,000 people
- Sponsor
- Scientific Institute San Raffaele
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