Clinical trials: Myocardial Ischemia
Coronary Heart Disease, Stable Angina Pectoris
BuMA OCT Study(A Comparative Evaluation of the Extent of Neointima Formation at 3 Months After Implantation Using OCT)
The objective of this study is a comparative evaluation of BuMA stent and of EXCEL stent in terms of the extent of neointima formation at 3 months after implantation using OCT.
- Conditions
- Coronary Heart Disease, Stable Angina Pectoris, Unstable Angina Pectoris, Silent Myocardial Ischemia
- Trial name
- NCT01752582
- Testing
- BuMA stent, EXCEL stent
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sino Medical Sciences Technology Inc.
Myocardial Ischemia, CLOPIDOGREL, POOR METABOLISM of (Disorder)
Genotyping Influences Outcome of Coronary Artery Stenting
This study evaluated epidemiology and clinical outcome of clopidogrel related various genotyping in Korean patients who had undergone percutaneous coronary intervention as a all comer registry form.
- Trial name
- GENIUS (NCT02707445)
- Testing
- Clopidogrel
- Volunteers
- 5,000 people
- Sponsor
- Korea University Anam Hospital
Myocardial Ischemia, Coronary Artery Disease
Peripheral Endothelial Function Assessment of Patients on Ticagrelor vs. Clopidogrel Who Have Undergone PCI
Usage of antiplatelet agents and cardiac procedures such as coronary angioplasty has dramatically improved the morbidity and mortality associated with coronary artery disease.
- Conditions
- Myocardial Ischemia, Coronary Artery Disease, Endothelial Dysfunction
- Trial name
- NCT02469740
- Testing
- Ticagrelor, Clopidogrel
- Where
- Ireland
- Volunteers
- 61 people
- Sponsor
- University Hospital of Limerick
Myocardial Ischemia
Reassessment Strategy in the Diagnosis of Coronary Heart Disease in Elderly
Despite the effectiveness of beta-blockers and antiplatelet agents for secondary prevention of coronary heart disease, this treatments are underused in the elderly because of diagnosis uncertainty and underuse of efficient…
- Trial name
- IRIDIA (NCT00224575)
- Testing
- diagnosis reassessment, Diagnosis strategy and subsequent therapeutic reassessment
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocardial Ischemia, Ischemic Reperfusion Injury
Remote Ischemic Preconditioning in Elective Percutaneous Interventions
Myocardial injury occurs after percutaneous coronary intervention due to micro emboli, ischemia-reperfusion injury or side branch occlusion.
- Trial name
- NCT02581618
- Testing
- remote ischemic preconditioning
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Trakya University
Bone Diseases, Cardiovascular Diseases
CVD Risk and Health in Postmenopausal Phytoestrogen Users
To determine the acceptability and benefits of use of a dietary supplement of the phytoestrogen, genistein, versus placebo on heart disease risk factors, bone density, and psychosocial outcomes in postmenopausal women.
- Conditions
- Bone Diseases, Cardiovascular Diseases, Coronary Disease, Depression
- Trial name
- NCT00000613
- Testing
- dietary supplements, genistein, diet, soy proteins
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Multiple Risk Factor Intervention Trial for the Prevention of Coronary Heart Disease (MRFIT)
To determine for a group of men at high risk of death from coronary heart disease whether a special intervention program to lower serum cholesterol, reduce blood pressure, and eliminate cigarette smoking would result in a…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00000487
- Testing
- antihypertensive agents, smoking cessation, diet, fat-restricted
- Sponsor
- University of Minnesota
Cardiovascular Diseases, Coronary Disease
Program on Surgical Control of Hyperlipidemias (POSCH)
To determine whether a profound reduction in serum cholesterol level, induced and maintained by partial ileal bypass, would prevent a second heart attack among men and women who had one myocardial infarction and whose blood…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00000490
- Testing
- jejunoileal bypass, diet, fat-restricted
- Sponsor
- University of Minnesota
Myocardial Infarction, Ischemic Heart Disease
Half-Dose Radiopharmaceutical in Wide Beam Reconstruction
This study is recruiting patients already scheduled for a single photon emission computed tomography myocardial perfusion imaging (SPECT-MPI) test.
- Trial name
- REGA-1102 (NCT01499654)
- Testing
- Half-dose of the Tc99-m sestamibi (Cardiolite)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Edwin Wu
Cardiovascular Diseases, Coronary Disease
Emory Angioplasty Versus Surgery Trial (EAST)
To compare the efficacy of coronary artery bypass graft (CABG) surgery with percutaneous transluminal coronary angioplasty (PTCA) in patients with multiple vessel coronary heart disease.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00000465
- Testing
- angioplasty, transluminal, percutaneous coronary, coronary artery bypass
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Atherosclerosis, Cardiovascular Diseases
Cholesterol Reduction in Seniors Program (CRISP)
To conduct a pilot study to determine whether lowering elevated serum cholesterol levels with 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG CoA) reductase inhibitors reduced mortality due to the sequelae of atherosclerotic…
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Coronary Disease, Heart Diseases
- Trial name
- NCT00000477
- Testing
- lovastatin
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Coronary Artery Surgery Study (CASS)
To compare coronary artery surgery with medical management in patients with coronary artery disease and to maintain a registry on all patients undergoing coronary arteriography, whether operatively or medically managed.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00000489
- Testing
- coronary artery bypass
- Sponsor
- University of Washington
Cardiovascular Diseases, Coronary Arteriosclerosis
Estrogen and Graft Atherosclerosis Research Trial (EAGER)
To determine if postmenopausal hormone replacement therapy in women following coronary bypass surgery would reduce the occurrence of graft occlusion and delay the development of graft atherosclerosis.
- Conditions
- Cardiovascular Diseases, Coronary Arteriosclerosis, Coronary Disease, Heart Diseases
- Trial name
- NCT00000605
- Testing
- hormone replacement therapy, estrogens, medroxyprogesterone
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Ischemic Heart Disease Incidence and Indices of Body-fat Distribution
To determine the association between ischemic heart disease incidence and anthropometric indices of body-fat distribution.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00005255
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Hostility and Coronary Risk--Role of Weak Vagal Function
To determine whether deficient vagal antagonism of sympathetic nervous system (SNS) actions on the heart contributed to increased coronary heart disease risk in hostile persons.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00005337
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Heart Diseases, Cardiovascular Diseases
Acute Cardiac Ischemia in Women in the ACI/TIPI Trial
To conduct a series of five inter-related studies on acute cardiac ischemia (ACI) in women.
- Conditions
- Heart Diseases, Cardiovascular Diseases, Angina Pectoris, Myocardial Ischemia
- Trial name
- NCT00005701
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Intravenous Streptokinase in Acute Myocardial Infarction
To determine whether the administration of intravenous streptokinase (SK) early in the course of acute, transmural myocardial infarction would limit myocardial damage.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00000507
- Testing
- streptokinase
- Sponsor
- University of Washington
Cardiovascular Diseases, Coronary Disease
HDL-Atherosclerosis Treatment Study (HATS)
To measure the effects of lipid-lowering drugs and/or antioxidant vitamins on progression or regression of coronary heart disease as measured by quantitative angiography in patients with low high density lipoprotein (HDL)…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00000553
- Testing
- simvastatin, niacin, antioxidants
- Sponsor
- University of Washington
Cardiovascular Diseases, Coronary Disease
Myocardial Infarction Triage and Intervention Project (MITI)
To determine the practicality, benefit, and safety of paramedic administration of thrombolytic therapy for acute myocardial infarction.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00000468
- Testing
- tissue plasminogen activator
- Sponsor
- University of Washington
Cardiovascular Diseases, Heart Diseases
Community Structure and Cardiovascular Mortality Trends
To assess the relationship of community socioeconomic (SE) structure to cardiovascular disease and all-cause mortality trends in the United States.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Ischemia, Cerebrovascular Disorders
- Trial name
- NCT00005245
- Sponsor
- University of North Carolina, Chapel Hill